Dab Tsi Koj Yuav Tsum Paub Txog MTHFR Cov Noob

Zoo Siab

• Lwm yam hloov ntawm MTHFR hloov pauv
• Cov tsos mob ntawm MTHFR hloov pauv
• Kev xeem rau MTHFR hloov pauv
• Kev khomob rau kev txhawj xeeb txog kev noj qab haus huv
• Lwm yam mob hauv plab
• Muaj peev xwm txhawb ntxiv
• Kev txiav txim siab ntawm kev noj haus
• Cov nqa mus

Peb suav nrog cov khoom uas peb xav tias tseem ceeb rau peb cov nyeem. Yog tias koj yuav los ntawm cov txuas hauv nplooj ntawv no, peb yuav khwv tau nyiaj me me. Ntawm no yog peb cov txheej txheem.

MTHFR yog dab tsi?

Koj yuav pom cov ntawv luv hais “MTHFR” tshwm sim nyob rau hauv xov xwm kev noj qab haus huv tsis ntev los no. Tej zaum nws yuav zoo li yog cov lus foom thaum xub thawj siab, tab sis nws yeej hais txog qhov muaj caj ces cuam tshuam.

MTHFR sawv methylenetetrahydrofolate reductaseCov. Nws tau txais kev saib xyuas vim muaj kev hloov caj ces uas yuav ua rau muaj ntau homocysteine ​​hauv cov ntshav thiab cov qib folate thiab lwm yam vitamins.

Muaj kev txhawj xeeb tias qee qhov teeb meem kev noj qab haus huv cuam tshuam nrog MTHFR kev sib txheeb, yog li kev sim tau dhau los ua lub hauv paus ntau xyoo dhau los.

Lwm yam hloov ntawm MTHFR hloov pauv

Koj tuaj yeem muaj ib lossis ob qho kev sib hloov - lossis tsis - ntawm MTHFR noob. Cov kev sib hloov no feem ntau hu ua variants. Ib qho sib txawv yog ib feem ntawm cov DNA ntawm cov gene uas sib txawv, lossis txawv, ntawm ib tug neeg mus rau lwm tus.

Muaj ib qho txawv - heterozygous - yog qhov tsawg dua uas yuav pab txhawb rau kev noj qab haus huv. Qee tus neeg ntseeg tias muaj ob qho kev sib hloov - homozygous - tuaj yeem ua rau muaj teeb meem loj dua. Muaj ob qho sib txawv, lossis cov foos, ntawm kev hloov pauv uas tuaj yeem tshwm sim rau MTHFR gene.

Cov kev hloov tshwj xeeb yog:

• C677T. Txog 30 txog 40 feem pua ​​ntawm cov neeg Asmeskas yuav muaj qhov hloov ntawm noob C677T. Kwv yees li 25 feem pua ​​ntawm cov neeg ntawm haiv neeg Hispanic, thiab 10 rau 15 feem pua ​​ntawm Caucasian qhovntsej, yog homozygous rau qhov sib txawv no.
• A1298C. Tsuas muaj kev tshawb nrhiav tsawg tsawg txog cov kev sib txawv no. Cov kev tshawb fawb muaj feem ntau yog thaj chaw lossis haiv neeg pawg. Piv txwv li, ib qho kev tshawb fawb xyoo 2004 tsom rau 120 cov ntshav pub dawb ntawm Irish cov cuab yeej cuab tam. Ntawm cov neeg pub nyiaj, 56, lossis 46.7 feem pua, tau hais txog hom kabmob no, thiab 11, lossis 14,2 feem pua, tau homozygous.
• Nws kuj tseem tuaj yeem tau txais ob qho C677T thiab A1298C kev hloov pauv, uas yog ib daim ntawv luam ntawm txhua.

Cov noob caj noob ces yog xeeb leej xeeb ntxwv, uas txhais tau tias koj tau lawv los ntawm koj niam koj txiv. Thaum xeeb tub, koj tau txais ib daim ntawv theej ntawm MTHFR gene los ntawm niam txiv. Yog tias ob qho tib si muaj kev sib hloov, koj qhov kev pheej hmoo ntawm kev muaj homozygous hloov dua siab dua.

Cov tsos mob ntawm MTHFR hloov pauv

Cov tsos mob txawv ntawm ib tug neeg mus rau lwm tus thiab ntawm txawv rau yam ntxwv. Yog tias koj ua qhov kev tshawb nrhiav hauv online ceev, koj yuav pom ntau lub vev xaib thov MTHFR ncaj qha ua rau ntau cov xwm txheej.

Nco ntsoov tias kev tshawb nrhiav puag ncig MTHFR thiab nws cov kev cuam tshuam tseem hloov zuj zus. Cov pov thawj txuas nrog feem ntau ntawm cov mob no rau MTHFR tab tom muaj tsis txaus los yog ua tsis ncaj.

Ntau dua li, tshwj tsis yog koj muaj teeb meem lossis kev sim ua tiav, koj yuav tsis paub txog koj li MTHFR kev hloov pauv.

Cov xwm txheej uas tau thov tawm los txuam nrog MTHFR suav nrog:

• mob plawv thiab cov ntshav hlab plawv (tshwj xeeb cov ntshav txhaws, mob stroke, embolism, thiab mob plawv)
• kev nyuaj siab
• ntxhov siab
• kev puas siab puas ntsws bipolar
• mob schizophrenia
• mob hnyuv
• mob leukemia
• mob mob thiab qaug zog
• leeg mob
• yastes yastaw
• rov muaj dua me nyuam hauv cov poj niam hnub nyoog muaj menyuam
• cev xeeb tub nrog cov leeg neural tsis xws luag, zoo li spina bifida thiab anencephaly

Kawm ntxiv txog kev muaj cev xeeb tub nrog MTHFR.

Txoj kev pheej hmoo yuav muaj nce ntxiv yog tias ib tus neeg muaj ob lub noob hloov pauv lossis yog homozygous rau kev hloov pauv MTHFR.

Kev xeem rau MTHFR hloov pauv

Muaj ntau lub koomhaum saib xyuas kev noj qab haus huv - suav nrog American College ntawm Obstetricians thiab Gynecologist, Tsev Kawm Qib Siab American Pathologist, American College of Medical Genetics, thiab American Heart Association - tsis xav kom kuaj cov kabmob sib txawv tshwj tsis yog tias ib tus neeg muaj ntau homocysteine ​​qib lossis lwm yam kev qhia txog kev noj qab haus huv.

Tseem, koj yuav xav paub los nrhiav koj tus kheej MTHFR xwm txheej. Txiav txim siab mus ntsib koj tus kws kho mob thiab sib tham txog qhov zoo thiab qhov zoo ntawm kev sim.

Nco ntsoov tias kev tshuaj ntsuam caj ces tej zaum yuav tsis tiv thaiv los ntawm koj cov nyiaj pov hwm. Hu rau koj tus cab kuj yog tias koj xav tias yuav mus kuaj kom nug txog cov nqi.

Qee cov khoom siv sim tshuaj tua kab mob hauv tsev muaj kev ntsuam xyuas rau MTHFR thiab. Piv txwv li:

• 23andMe yog qhov kev xaiv nrov uas muab cov ntaub ntawv hauv keeb kwm thiab kev noj qab haus huv. Nws tseem pheej yig ($ 200). Txhawm rau ntsuas qhov no, koj tso cov qaub ncaug rau hauv ib lub raj thiab xa nws los ntawm kev xa ntawv mus rau qhov chaw kuaj ntshav. Cov txiaj ntsig siv mus rau rau yim lub lis piam.
• Kuv Lub Tsev MTHFR ($ 150) yog lwm txoj kev xaiv hais tshwj xeeb hauv kev hloov pauv. Qhov kev ntsuam xyuas yog ua los ntawm kev khaws DNA ntawm sab hauv ntawm koj sab plhu nrog swabs. Tom qab xa cov hnoos qeev, cov txiaj ntsig yuav siv li ib mus rau ob lis piam.

Kev khomob rau kev txhawj xeeb txog kev noj qab haus huv

Muaj MTHFR kev hloov pauv tsis tau txhais tau tias koj xav tau kev kho mob. Nws tsuas txhais tau tias koj yuav tsum noj tshuaj vitamin B pab ntxiv.

Kev kho yog ib txwm yuav tsum tau ua thaum koj muaj homocysteine ​​ntau ntau, yuav luag ib txwm nyob siab tshaj qhov qib tau los ntawm feem ntau MTHFR hloov. Koj tus kws kho mob yuav tsum txiav txim siab tawm lwm qhov peev xwm ua kom muaj ntau homocysteine, uas tuaj yeem tshwm sim nrog lossis tsis muaj MTHFR hloov pauv.

Lwm qhov ua rau siab homocysteine ​​suav nrog:

• hypothyroidism
• cov mob xws li ntshav qab zib, ntshav siab, thiab ntshav siab
• kev rog dhau thiab kev tsis dhau kev ua haujlwm
• qee cov tshuaj, xws li atorvastatin, fenofibrate, methotrexate, thiab nicotinic acid

Los ntawm qhov ntawd, txoj kev kho yuav nyob ntawm qhov laj thawj thiab tsis tas yuav yog tus saib xyuas MTHFR. Muaj kev zam tau yog thaum koj tau kuaj pom koj tus mob nrog txhua yam mob ntawm lub sijhawm no:

• siab homocysteine ​​ntau ntau
• MTHFR hloov pauv kom paub meej
• cov vitamins tsis muaj zog hauv cov folate, choline, lossis vitamins B-12, B-6, lossis riboflavin

Hauv cov rooj plaub no, koj tus kws kho mob tuaj yeem hais qhia ntxiv kom daws cov teeb meem tsis txaus nrog rau cov tshuaj lossis kev kho mob los kho cov kev mob tshwj xeeb.

Cov neeg uas muaj MTHFR kev hloov pauv yuav tseem xav kom ua cov kev tiv thaiv los txo lawv tus kheej homocysteine. Ib qho kev tiv thaiv yog hloov qee yam kev xaiv ua neej, uas tuaj yeem pab yam tsis muaj kev siv tshuaj. Piv txwv li:

• txiav kev haus luam yeeb, yog koj haus luam yeeb
• ua kom tawm dag zog txaus
• noj zaub mov kom zoo rau lub cev, sib npaug

Lwm yam mob hauv plab

Rov ua dua tshiab cov leeg tsis zoo thiab cov leeg hlab ntshav muaj teeb meem muaj feem nrog MTHFR. Lub chaw Genetic thiab Rare Cov Ntaub Ntawv Qhia Txog Kev Tshawb Fawb tau hais tias kev tshawb fawb qhia tias cov poj niam uas muaj ob hom C677T muaj qhov tsis zoo yog muaj kev pheej hmoo ntawm menyuam muaj lub cev tsis zoo.

Qhov kev tshawb nrhiav xyoo 2006 tau saib rau cov poj niam uas muaj keeb kwm txog kev rov ua menyuam yaus. Nws pom tias 59 feem pua ​​ntawm lawv muaj ntau homozygous hloov kev sib raug zoo, suav nrog MTHFR, cuam tshuam nrog ntshav txhaws, piv rau tsuas yog 10 feem pua ​​ntawm cov poj niam hauv pawg tswj hwm.

Tham nrog koj tus kws kho mob txog kev sim yog tias ib qho ntawm cov xwm txheej hauv qab no siv rau koj:

• Koj tau ntsib ntau txoj kev nchuav me me uas tsis tau piav qhia.
• Koj muaj menyuam yaus tsis muaj hlab hlab neural.
• Koj paub tias koj muaj MTHFR kev hloov pauv, thiab koj cev xeeb tub.

Txawm hais tias tsis muaj pov thawj los txhawb nws, qee cov kws kho mob pom zoo kom noj cov ntshav txhaws. Tseem yuav muaj cov tshuaj folate ntxiv thiab.

Muaj peev xwm txhawb ntxiv

Lub MTHFR noob hloov pauv tau txoj hauv kev lub cev ua cov txheej txheem folic acid thiab lwm yam tseem ceeb B vitamins. Hloov cov lus ntxiv ntawm cov khoom noj haus no yog qhov ua kom pom tseeb hauv kev tawm tsam nws cov teebmeem.

Folic acid yog qhov tseeb tias yog neeg tsim cov folate, ib yam khoom noj muaj nyob hauv cov zaub mov. Kev noj cov faus muaj nyob hauv cov folate - methylated folate - tej zaum yuav pab koj lub cev nqus tau nws yooj yim.

Cov neeg feem coob raug txhawb kom noj cov tshuaj multivitamin uas muaj tsawg kawg 0.4 milligrams ntawm folic acid nyob rau txhua hnub.

Cov poj niam cev xeeb tub tsis raug txhawb kom hloov cov tshuaj muaj hnub yug los yog kev saib xyuas raws li lawv MTHFR ib leeg. Qhov no txhais tau tias noj cov koob tshuaj ib txwm ntawm 0.6 milligrams ntawm folic acid txhua hnub.

Cov poj niam muaj keeb kwm mob hlab ntsha tsis zoo yuav tsum tham nrog lawv tus kws kho mob txog qee qhov kev pom zoo.

Multivitamins muaj methylated folate suav nrog:

• Thorne Cov Khoom Siv Tsis Zoo 2 / Hnub
• Smarty Cov Laus Txom Nyem Ua tiav
• Mama Cov Menyuam Lub Cev Prenatal Vitamins

Tham nrog koj tus kws kho mob ua ntej pauv cov vitamins thiab cov tshuaj ntxiv. Qee yam yuav cuam tshuam nrog lwm cov tshuaj lossis kev kho koj tus mob uas koj tau txais.

Koj tus kws kho mob tseem yuav hais qhia cov vitamins uas muaj folate thiab folic acid. Nyob ntawm koj qhov kev pov hwm, cov nqi ntawm cov kev xaiv no tuaj yeem sib txawv hauv qhov sib piv rau ntau yam tsis sib xws.

Kev txiav txim siab ntawm kev noj haus

Noj cov zaub mov uas muaj folate ntau dua tuaj yeem pab txhawb koj lub cev kom ntau ntau ntawm cov vitamin tseem ceeb no. Txawm li cas los xij, kev txhawb nqa tseem yuav tsim nyog.

Cov kev xaiv zaub mov zoo muaj xws li:

• cov nqaijrog zoo li taum pauv, taum pauv, thiab lentils
• veggies xws li zaub ntsuab, zaub ntsuab, zaub xas lav, beets, zaub cob pob, pob kws, Zaub pob, thiab bok choy
• txiv ntoo zoo li cantaloupe, zib ntab, txiv tsawb, txiv pos, txiv kab ntxwv qaub, thiab txiv pos nphuab
• kua txiv xws li txiv kab ntxwv, txiv tsawb ntoo txiv ntoo, txiv kab ntxwv qaub, lws suav, lossis lwm yam kua zaub
• txiv laum huab xeeb
• paj noob hlis noob

Cov neeg uas muaj MTHFR hloov tau yuav xav kom tsis txhob noj zaub mov uas muaj cov faus faus, folic acid - tab sis cov pov thawj tsis meej tias qhov tsim nyog lossis muaj txiaj ntsig zoo.

Nco ntsoov tshawb xyuas cov ntawv cim, vim tias cov vitamins no tau ntxiv rau ntau cov noob nplej, xws li nplej zom, cereals, qhob cij, thiab cov lag luam muag tau cov hmoov nplej.

Kawm paub ntau ntxiv txog qhov sib txawv ntawm cov folate thiab folic acid.

Cov nqa mus

Koj li kev muaj mob ntawm MTHFR yuav yog lossis tsis cuam tshuam rau koj kev noj qab haus huv. Cov kev tshawb fawb ntxiv yog xav tau los txiav txim siab qhov muaj tseeb tiag, yog tias muaj, cuam tshuam nrog cov txawv.

Ib zaug ntxiv, ntau lub koom haum saib xyuas kev noj qab haus huv tsis pom zoo kom kuaj cov kev hloov no, tshwj xeeb yog tsis muaj lwm yam cim qhia txog kev kho mob. Tham nrog koj tus kws kho mob txog cov txiaj ntsig thiab qhov pheej hmoo ntawm kev xeem ntawv, nrog rau lwm qhov kev txhawj xeeb uas koj yuav muaj.

Txuas noj kom zoo, tawm dag zog, thiab xyaum ua lwm yam kev noj qab haus huv niaj hnub los txhawb koj txoj kev noj qab nyob zoo.