Metabolic Alkalosis

Zoo Siab

• Dab tsi yog cov metabolic alkalosis?
• Kev kho mob ntawm metabolic alkalosis
• Chloride-teb
• Chloride-tiv taus
• Cov tsos mob ntawm metabolic alkalosis
• Yuav ua li cas lub cev them nyiaj rau cov metabolic alkalosis
• Lub ntsws raug mob
• Nyiaj them raum
• Ua rau cov metabolic alkalosis
• Kev kuaj mob ntawm metabolic alkalosis
• Nkag siab txog pH qib
• Kev tsom xam cov zis
• Cov kab mob alkalosis nrog hypochloremia
• Outlook ntawm metabolic alkalosis

Dab tsi yog cov metabolic alkalosis?

Kev zom zaub mov yog cov mob uas tshwm sim thaum koj cov ntshav hnyav dhau lawm alkaline. Alkaline yog rov qab ntawm acidic.

Peb lub cev ua haujlwm tau zoo tshaj plaws thaum cov acidic-alkaline sib npaug ntawm peb cov ntshav tsuas yog me ntsis qaij mus rau alkaline.

Alkalosis tshwm sim thaum koj lub cev muaj:

• ntau dhau alkali-ua bicarbonate ions
• dhau ob peb cov kua qaub ua cov pa hydrogen ions

Ntau tus neeg tsis hnov ​​cov tsos mob tshwm sim ntawm metabolic alkalosis, yog li koj yuav tsis paub tias koj muaj tus mob no.

Cov kab mob alkalosis yog ib ntawm plaub hom loj ntawm alkalosis. Nws muaj ob hom kev mob plab metabolic:

• Chloride-teb alkalosis tshwm sim los ntawm poob ntawm hydrogen ions, feem ntau los ntawm ntuav lossis lub cev qhuav dej.
• Chloride-resistant alkalosis cov txiaj ntsig thaum koj lub cev khaws cov bicarbonate (alkaline) ntau dhau los, lossis thaum muaj hydrogen ions pauv ntawm koj cov ntshav mus rau koj cov ntshav.

Nws tseem muaj qhov mob hu ua metabolic acidosis uas tau tshwm sim thaum koj cov ntshav lossis kua dej dhau mus ua kua qaub.

Koj lub cev them nyiaj rau ob qho tib si alkalosis thiab acidosis los ntawm koj lub ntsws. Lub ntsws hloov lub siab ntawm koj cov ntshav los ntawm kev tso cai ntau los yog tsawg carbon dioxide kom dim thaum koj ua pa. Lub raum tseem ua lub luag haujlwm los ntawm kev tswj hwm kev tshem tawm ntawm bicarbonate ions.

Xav tau kev kho mob thaum twg cov kev pab them nqi ua tsis txaus.

Kev kho mob ntawm metabolic alkalosis

Kev kho mob rau cov teeb meem metabolic yog nyob ntawm seb koj lub cev muaj teeb meem dab tsi
chloride-teb los yog chloride-resistant. Nws kuj yog nyob ntawm qhov pib ua ntawm alkalosis.

Chloride-teb

Yog tias koj muaj tsuas yog muaj cov tshuaj chloride me-tiv thaiv cov alkalosis, koj tsuas yog xav tau hloov kho hauv koj cov zaub mov noj, xws li nce koj cov ntsev ntxiv (sodium chloride). Cov chloride ions yuav ua rau koj cov ntshav muaj acidic thiab txo cov alkalosis.

Yog tias koj tus kws kho mob txiav txim siab koj lub alkalosis xav tau kev pab sai sai, lawv yuav muab ib qho tshuaj IV rau koj (tso kua dej) uas muaj cov tshuaj ntsev (sodium chloride).

Qhov IV yog tus txheej txheem yuav luag tsis mob. Nws cuam tshuam nrog ntxig ib rab koob me me rau hauv cov hlab ntsha hauv koj txhais caj npab. Lub koob txuas los ntawm lub raj xa mus rau lub hnab ntim tsis huv uas muaj ntsev yaj nyob rau hauv dej. Qhov no ib txwm ua nyob hauv tsev kho mob.

Chloride-tiv taus

Yog hais tias koj muaj chloride-resistant alkalosis, koj lub cev yuav ploj mus ntawm potassium. Cov tshuaj sodium chloride yuav pab tsis tau koj thiab tuaj yeem tsim cov teeb meem tsis zoo. Koj tus kws kho mob yuav saib xyuas cov hauv kev kom nce poov tshuaj.

Koj tuaj yeem nce koj cov poov tshuaj ntau ntxiv los ntawm:

• noj tshuaj uas muaj poov tshuaj chloride ob mus rau plaub zaug hauv ib hnub (raws li kws kho mob tau qhia)
• tau txais cov tshuaj potassium chloride ua ke kom zoo

Cov tsos mob ntawm metabolic alkalosis

Cov kab mob metabolic alkalosis yuav tsis pom muaj tsos mob dab tsi. Cov neeg muaj hom alkalosis no pheej yws yws ntawm cov cag pwm hauv qab uas ua rau nws. Cov no tuaj yeem suav nrog:

• ntuav
• zawv plab
• o hauv ob txhais ceg qis (ntu ntu)
• nkees

Cov mob hnyav ntawm lub cev metabolic alkalosis tuaj yeem ua rau:

• ntxhov siab
• kev tsis zoo
• qaug dab peg
• coma

Cov tsos mob hnyav feem ntau tshwm sim thaum cov alkalosis tshwm sim los ntawm daim siab mob siab ntev.

Yuav ua li cas lub cev them nyiaj rau cov metabolic alkalosis

Ob lub plab hnyuv siab raum pab txhawm rau los pab them rau metabolic alkalosis - peb lub ntsws thiab lub raum.

Lub ntsws raug mob

Peb lub cev tsim cov pa roj carbon dioxide thaum peb hloov cov zaub mov uas peb noj mus rau lub zog hauv peb lub hlwb. Cov ntshav liab nyob rau hauv peb cov leeg txais txoj pa roj carbon dioxide thiab nqa mus rau peb lub ntsws kom ua pa tawm.

Thaum cov pa roj carbon dioxide sib xyaw nrog cov dej hauv cov ntshav, nws tsim cov kua qaub, hu ua carbonic acid. Cov carbonic acid ces tawg tawm mus rau bicarbonate ion thiab hydrogen. Bicarbonate ions yog alkaline.

Los ntawm kev hloov tus nqi ntawm kev ua pa, peb tuaj yeem tsa lossis txo qis qhov kev txiav txim siab ntawm alkaline bicarbonate ions uas tau khaws cia hauv peb cov ntshav. Lub cev ua qhov no cia li nyob rau hauv tus txheej txheem hu ua kev them nyiaj ua pa. Nov yog lub cev thawj zaug thiab teb tau sai tshaj plaws.

Txhawm rau them rau alkalosis, cov cim raug xa mus qeeb rau tus nqi ntawm kev ua pa.

Nyiaj them raum

Lub raum tuaj yeem pab tua cov alkalosis los ntawm kev ua kom muaj qhov quav ntxiv ntawm bicarbonate ions los ntawm kev tso zis. Qhov no kuj tseem yog tus txheej txheem tsis siv neeg, tab sis nws qeeb qeeb dua li kev them nyiaj ua pa.

Ua rau cov metabolic alkalosis

Ntau qhov sib txawv ua rau muaj peev xwm ua rau cov plab hnyuv taum pauv. Cov no suav nrog:

Poob plab zom mov. Qhov no yog qhov teeb meem feem ntau ua rau kev mob plab hnyuv taum alkalosis. Feem ntau nws ntuav ntuav los yog nqus tau los ntawm txoj hlab muab qhov ntswg.

Lub plab zom zaws muaj cov ntsiab lus siab ntawm hydrochloric acid, muaj zog acid.Nws poob ua rau nce ntau ntxiv nyob hauv lub alkalinity ntawm cov ntshav.

Qhov ntuav tuaj yeem tshwm sim los ntawm ntau qhov ntawm lub plab tsis zoo. Los ntawm kev xam thiab kev kho qhov ua rau ntuav, koj tus kws kho mob yuav kho tus metabolic alkalosis.

Tshaj ntawm antacids. Antacid kev siv yuav tsis nquag ua rau lub plab zom mov coj mus ua haujlwm. Tab sis yog tias koj muaj lub raum tsis ua haujlwm lossis tsis ua haujlwm thiab siv lub tshuaj tsis haum tshuaj, nws tuaj yeem nqa ntawm alkalosis. Cov tshuaj tsis haum rau lub cev muaj cov txhuas hydroxide lossis magnesium hydroxide.

Kev tshuaj ntsuab. Qee qhov diuretics (dej tshuaj) feem ntau siv rau cov ntshav siab tuaj yeem ua rau tso zis ntau ntxiv urinary acid. Kev ua kom muaj kua qaub ntau ntxiv rau hauv cov zis tuaj yeem ua rau koj cov ntshav muaj roj ntau.

Yog hais tias alkalosis pom tshwm thaum koj tab tom noj tshuaj xws li thiazide lossis voj diuretics, koj tus kws kho mob yuav hais kom koj tsum.

Cov poov tshuaj tsis muaj zog (hypokalemia). Kev tsis muaj cov poov tshuaj tuaj yeem ua rau cov hydrogen ions ib txwm muaj nyob hauv cov kua dej nyob ib ncig ntawm koj lub hlwb hloov mus rau sab hauv lub hlwb. Qhov tsis muaj cov acidic hydrogen ions ua rau koj cov dej thiab ntshav ntau ua alkaline.

Txo cov ntshav ntau hauv cov hlab ntsha (EABV). Qhov no tuaj yeem los ntawm ob lub siab tsis muaj zog thiab los ntawm kev mob ntsws. Kev txo ntshav txaus ua rau koj lub cev tsis muaj peev xwm tshem tawm cov alkaline bicarbonate ions.

Lub plawv, raum, lossis lub siab ua haujlwm poob. Cov kab mob ua rau lub cev muaj txiaj ntsig tuaj yeem tshwm sim los ntawm qhov tsis ua haujlwm ntawm lub cev loj, xws li koj lub plawv, raum, lossis nplooj siab. Qhov no ua rau cov poov tshuaj depletion.

Ib qho kev daws teeb meem ntsev (sodium chloride) tuaj yeem ua rau ntau yam tsis zoo los ntawm kev ua rau koj lub cev khaws cov dej uas tsis tas yuav ua rau cov bicarbonate ions uas ua rau muaj cov alkalosis.

Cov noob caj noob ces. Tsis tshua muaj qee qhov, cov kab mob muaj caj ces tuaj yeem yog qhov ua kom muaj cov metabolic alkalosis. Tsib kab mob qub txeeg qub teg uas tuaj yeem ua rau metabolic alkalosis yog:

• Bartter mob
• Gitelman syndrome
• Mob pob ntseg
• glucocorticoid daws tau aldosteronism
• pom meej mineralocorticoid ntau heev

Kev kuaj mob ntawm metabolic alkalosis

Txhawm rau pib kuaj mob, koj tus kws kho mob yuav siv koj li keeb kwm kho mob thiab muab tshuaj xyuas lub cev.

Yog tias lawv xav tias yog alkalosis, lawv yuav kuaj koj cov ntshav thiab zis. Lawv yuav xyuas qib uas qhia txog oxygen thiab carbon dioxide nyob hauv koj cov hlab ntsha thiab ntsuas cov acidity thiab alkalinity ntawm koj cov ntshav.

Nkag siab txog pH qib

Kev acidity los yog alkalinity ntawm kua yog ntsuas ntawm lub nplai hu ua pH. Hauv metabolic alkalosis, pH ntawm koj cov ntshav siab.

Qhov feem ntau tsis sib haum xeeb, dej, muaj ib qho pH ntawm 7. Thaum lub pH ntawm cov kua dej ntog hauv qab 7, nws ua kua qaub. Thaum nws nce siab dua 7, nws yog alkaline.

Koj cov ntshav ib txwm muaj pH los ntawm 7.35 rau 7.45, lossis me ntsis alkaline. Thaum cov pH nce siab siab dua tus lej no, koj muaj cov metabolic alkalosis.

Kev tsom xam cov zis

Koj tus kws kho mob yuav kuaj ntsuas cov tshuaj chloride thiab potassium ions ntau nyob hauv koj cov zis.

Thaum cov tshuaj chloride theem qis, nws qhia tau tias koj tuaj yeem kho kev kho mob nrog cov tshuaj qab ntsev Kev noj cov poov tshuaj tsawg yuav qhia tau cov poov tshuaj tsis haum lossis siv cov tshuaj tso quav ntau dhau.

Cov kab mob alkalosis nrog hypochloremia

Kev ua tshuaj Hypochloremia txhais tau hais tias koj muaj cov tshuaj chloride ion me me rau hauv koj cov ntshav.

Mob Hypochloremic alkalosis yog ib qho mob hnyav uas tuaj yeem ua rau koj poob siab. Nws tuaj yeem tshwm sim los ntawm lub cev qhuav dej thiab lwm cov laj thawj.

Qhov zoo, nws tuaj yeem kho los ntawm kev ua tiav ntsev (ntsev) tshuaj. Qhov no tuaj yeem xa los ntawm IV yog tias koj muaj mob hnyav, lossis los ntawm kev kho rau koj cov zaub mov noj hauv qee kis mob me.

Outlook ntawm metabolic alkalosis

Kev zom zaub mov hauv plab feem ntau tshwm sim los ntawm kev ntuav ntau ntuav uas ua rau koj poob kua tej kua qaub hauv koj lub plab. Qhov no feem ntau yuav rov qab los ntawm kev kho nrog dej qab ntsev.

Nws tuaj yeem yog qhov txiaj ntsig ntawm cov poov tshuaj tsis muaj zog lossis chloride tsis muaj. Qhov tsis zoo no tuaj yeem kho nrog kua dej los yog, ntawm qee qhov xwm txheej me, nrog kev noj zaub mov noj kom haum.

Qee qhov xwm txheej ntawm alkalosis tshwm sim los ntawm mob hnyav lub plawv, raum, lossis mob siab. Thaum lub sij hawm alkalosis feem ntau tuaj yeem thim rov qab rau hauv lub sijhawm luv luv, qhov mob hauv qab yuav tsum tau kho rau qhov kho tau ntev.

Ntsib koj tus kws kho mob yog tias koj tau pom muaj cov tsos mob tshiab lossis ntev kawg.