Latuda (lurasidone): nws yog dab tsi rau, yuav ua li cas coj nws thiab phiv

Zoo Siab

• Dab tsi yog nws rau
• Yuav noj li cas
• Muaj kev phiv ntau
• Leej twg yuav tsum tsis txhob coj

Lurasidone, paub los ntawm kev lag luam lub npe Latuda, yog cov tshuaj hauv chav kawm tiv thaiv kev puas hlwb, siv los kho cov tsos mob ntawm tus mob schizophrenia thiab kev nyuaj siab tshwm sim los ntawm kev puas siab puas ntsws bipolar.

Cov tshuaj no tau txais kev pom zoo tsis ntev los no Anvisa coj mus muag hauv cov chaw muag tshuaj hauv Brazil, hauv 20mg, 40mg thiab 80mg ntsiav tshuaj, hauv pob 7, 14, 30 lossis 60 ntsiav tshuaj, thiab tuaj yeem nrhiav lossis txiav txim siab hauv cov chaw muag tshuaj loj. Raws li nws yog ib qho tshuaj tiv thaiv kev ntxhov siab, Lurasidone yog ib feem ntawm cov qeb ntawm cov tshuaj tswj tau thiab muag tsuas yog muaj cov tshuaj tshwj xeeb hauv ob daim ntawv luam.

Dab tsi yog nws rau

Lurasidone yog siv los kho:

• Schizophrenia, rau cov neeg laus thiab cov hluas uas muaj hnub nyoog 13 txog 18 xyoo;
• Kev nyuaj siab cuam tshuam nrog kev puas siab puas ntsws bipolar, rau cov neeg laus, raws li kev noj tshuaj ib leeg lossis koom nrog lwm tus, xws li lithium lossis valproate.

Cov tshuaj no yog cov tshuaj tiv thaiv kev tawm tsam, uas ua haujlwm zoo rau kev tiv thaiv kev tiv thaiv ntawm kev cuam tshuam ntawm dopamine thiab monoamine, uas yog lub hlwb cov hlwb ua haujlwm, tseem ceeb rau kev txhim kho cov tsos mob.

Txawm li cas los xij, nws ua haujlwm nrog qee qhov kev txhim kho hauv kev piv rau cov laus tiv thaiv kev tiv thaiv, xws li kev hloov pauv me me hauv cov metabolism, muaj kev cuam tshuam tsawg dua rau qhov hnyav nce thiab kev hloov hauv lub cev rog thiab cov ntshav qab zib.

Yuav noj li cas

Lurasidone ntsiav tshuaj yuav tsum tau noj qhov ncauj, ib zaug ib hnub, ua ke nrog pluas noj, thiab nws raug nquahu kom noj thaum tib lub sijhawm txhua hnub. Ntxiv rau, cov ntsiav tshuaj yuav tsum nqos tag nrho, kom tsis txhob muaj lawv iab iab.

Muaj kev phiv ntau

Qee qhov kev mob tshwm sim feem ntau ntawm Lurasidone yog kev tsaug zog, nyob tsis tswm, kiv taub hau, qoj ib ce tsiv, pw tsis tsaug zog, ntxhov siab, ntxhov siab lossis hnyav nce.

Lwm yam ua tau tshwm sim yog qaug dab peg, tsis qab los, nqhis dej, pom kev plooj plooj, tachycardia, hloov ntshav siab, kiv taub hau lossis hloov ntshav suav, piv txwv.

Leej twg yuav tsum tsis txhob coj

Lurasidone yog contraindicated nyob rau hauv lub xub ntiag ntawm:

• Hypersensitivity rau cov nquag khoom lossis rau ib yam ntawm cov excipients hauv ntsiav tshuaj;
• Siv cov tshuaj CYP3A4 inhibitory muaj zog, xws li Boceprevir, Clarithromycin, Voriconazole, Indinavir, Itraconazole lossis Ketoconazole, piv txwv;
• Kev siv cov tshuaj CYP3A4 tsim muaj zog, xws li Carbamazepine, Phenobarbital, Phenytoin, Rifampicin lossis St. John's wort, piv txwv.

Vim tias muaj kev cuam tshuam nrog cov txiaj ntsig ntawm cov tshuaj no, cov npe siv tshuaj yuav tsum tau qhia tas li rau tus kws kho mob nrog.

Lurasidone yuav tsum tau siv nrog kev ceev faj los ntawm cov neeg muaj mob raum los sis mob me mus rau mob siab rau daim siab, Parkinson tus kab mob, kev txav mus los, mob plawv lossis lwm cov kab mob paj hlwb. Ntxiv rau, cov tshuaj no tseem tsis tau sim rau cov neeg laus laus uas muaj dementia lossis hauv menyuam yaus, yog li kev siv yuav tsum zam nyob rau hauv cov teeb meem no.