Isoniazid nrog Rifampicin: mechanism ntawm kev coj ua thiab phiv
Zoo Siab
Isoniazid nrog rifampicin yog cov tshuaj siv rau kev kho mob thiab tiv thaiv kab mob ntsws, thiab tuaj yeem cuam tshuam nrog lwm cov tshuaj.
Qhov kev hais daws no muaj nyob hauv cov khw muag tshuaj tab sis tsuas yog muab tau los ntawm kev qhia txog cov tshuaj kho mob thiab yuav tsum tau siv nrog kev ceev faj, vim yog cov lus tsis sib haum thiab cov kev mob tshwm sim uas nws nthuav qhia.
Yuav siv li cas
Hauv txhua txhua daim ntawv ntsig txog mob ntsws thiab mob ntsws, tsuas yog ua rau mob rau daim npog thiab cov neeg mob ntau tshaj 20 kg hauv qhov hnyav, lawv yuav tsum noj, txhua hnub, cov koob tshuaj uas qhia hauv qab no:
| Nyhav | Isoniazid | Rifampicin | Cov tshuaj ntsiav |
| 21 - 35 Kg | 200 mg | 300 mg | 1 tshuaj ntsiav ntawm 200 + 300 |
| 36 - 45 Kg | 300 mg | 450 mg | 1 tshuaj ntsiav ntawm 200 + 300 thiab lwm ntawm 100 + 150 |
| Ntau tshaj 45 Kg | 400 mg | 600 mg | 2 tsiav tshuaj ntawm 200 + 300 |
Qhov tshuaj yuav tsum tau muab rau hauv ib qho tshuaj noj, nyiam dua thaum sawv ntxov nyob rau ntawm lub plab khoob, lossis ob teev tom qab noj mov. Txoj kev kho yuav tsum tau nqa tawm mus 6 lub hlis, txawm li cas los xij tus kws kho mob yuav hloov qhov ntau npaum li cas.
Mechanism ntawm kev ua
Isoniazid thiab rifampicin yog cov tshuaj uas tawm tsam cov kab mob uas ua rau mob ntsws, hu ua Mycobacterium tuberculosis.
Isoniazid yog ib yam khoom uas inhibits kev faib tawm sai thiab ua rau muaj kev tuag ntawm mycobacteria, uas ua rau mob ntsws, thiab rifampicin yog cov tshuaj tua kab mob uas tiv thaiv qhov ntau ntau ntawm cov kab mob rhiab thiab txawm hais tias nws muaj kev tiv thaiv rau ntau yam kab mob, nws yog tshwj xeeb tshaj yog siv rau kev kho mob ruas thiab tuberculosis.
Leej twg yuav tsum tsis txhob siv
Cov tshuaj no yuav tsum tsis txhob siv rau hauv cov neeg uas muaj kev fab tshuaj rau ib qho twg hauv cov qauv, cov neeg muaj teeb meem mob siab lossis raum lossis cov neeg uas tab tom noj tshuaj uas tuaj yeem ua rau hloov pauv hauv daim siab.
Tsis tas li ntawd, nws tsis pom zoo rau siv rau cov menyuam yaus qis dua 20 kg ntawm lub cev nyhav, cov poj niam cev xeeb tub lossis cov neeg uas pub mis.
Muaj kev phiv ntau
Cov kev mob tshwm sim feem ntau tuaj yeem tshwm sim nrog kev siv cov tshuaj no yog qhov tsis hnov qab hauv qhov kawg xws li taw thiab txhais tes thiab hloov pauv hauv daim siab, tshwj xeeb tshaj yog rau cov neeg muaj hnub nyoog 35 xyoos.Neuropathy, feem ntau thim rov qab, yog tshwm sim feem ntau ntawm cov neeg tsis muaj zaub mov, haus dej cawv lossis cov neeg uas twb muaj teeb meem mob siab thiab thaum lawv tau txais tshuaj ntau ntawm isoniazid.
Ib qho ntxiv, vim tias muaj rab phom ravicin, tsis qab los, xeev siab, ntuav, raws plab thiab mob hnyuv kuj tuaj yeem tshwm sim.
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