Idiopathic Autoimmune Hemolytic Anemia

Zoo Siab

• Leej twg yuav muaj kev pheej hmoo?
• Cov tsos mob ntawm idiopathic AIHA
• Kev kuaj mob idiopathic AIHA
• Cov kev kho mob rau IAIHA
• Steroids
• Kev phais mob
• Kev tiv thaiv tshuaj
• Lub hom phiaj ncua ntev

Dab tsi yog idiopathic autoimmune hemolytic anemia?

Idiopathic autoimmune hemolytic anemia yog ib daim ntawv ntawm autoimmune hemolytic anemia. Autoimmune hemolytic anemia (AIHA) yog ib pab pawg tsis tshua muaj mob tab sis muaj ntshav tsis zoo. Lawv tshwm sim thaum lub cev rhuav cov qe ntshav liab sai dua li uas tsim tawm los. Ib tug mob raug suav tias yog idiopathic thaum nws qhov ua tsis paub.

Cov kab mob autoimmune tua lub cev nws tus kheej. Koj lub cev tiv thaiv kab mob ua rau cov tshuaj tiv thaiv txhawm rau pab lub hom phiaj txawv teb chaws ntxeem tau xws li cov kab mob thiab kab mob. Tus mob autoimmune tsis zoo, koj lub cev ua yuam kev los tsim cov tshuaj ua kom lub cev tua nws tus kheej. Hauv AIHA, koj lub cev tsim cov tshuaj tiv thaiv uas ua rau cov ntshav liab.

Idiopathic AIHA tuaj yeem txo txoj sia vim tias nws qhov pib sai. Nws yuav tsum tau txais kev kho mob sai thiab pw hauv tsev kho mob.

Leej twg yuav muaj kev pheej hmoo?

Hais txog ntawm tag nrho cov mob AIHA yog idiopathic. AIHA tuaj yeem tshwm sim thaum twg los tau hauv lub neej thiab tuaj yeem tsim dheev lossis maj mam. Nws raug ntau rau cov poj niam.

Yog tias AIHA tsis yog idiopathic, nws yog vim nws tau tshwm sim los ntawm tus kab mob tseem ceeb lossis tshuaj noj. Txawm li cas los xij, idiopathic AIHA tsis muaj qhov ua rau pom tseeb. Cov neeg uas muaj tus kabmob idiopathic AIHA tsuas yog kuaj cov ntshav tsis raug thiab tsis muaj tsos mob dab tsi.

Cov tsos mob ntawm idiopathic AIHA

Tej zaum koj yuav qaug zog thiab ua tsis taus pa yog tias koj pib mob ib ce sai ntawm idiopathic AIHA. Hauv lwm qhov xwm txheej, qhov mob no mob ntev thiab nthuav dav, yog li ntawd cov tsos mob tsis tshua pom tseeb. Hauv ob kis, cov tsos mob yuav suav nrog ib lossis ntau yam hauv qab no:

• nce qaug zog
• txog siav
• lub plawv dhia sai
• tawv nqaij daj ntseg lossis daj-xim
• mob leeg
• xeev siab
• ntuav
• cov zis tsaus nti
• mob taub hau
• tsam plab tsis xis nyob
• tsam plab
• zawv plab

Kev kuaj mob idiopathic AIHA

Koj tus kws kho mob yuav nrog koj tham txog koj cov tsos mob tshwj xeeb yog tias lawv xav tias koj muaj kabmob AIHA. Lawv yuav tsum kuaj koj los ntawm AIHA thiab txiav txim siab tawm cov tshuaj kho mob lossis lwm qhov tsis txaus ntseeg raws li qhov ua rau ntawm AIHA ua ntej kuaj mob koj nrog hom idiopathic.

Ua ntej, koj tus kws kho mob yuav nug koj txog koj li keeb kwm kev kho mob. Nws zoo li yuav lees paub koj mus cuag tsev kho mob kom paub sai thiab soj ntsuam yog tias koj tus mob hnyav heev. Cov piv txwv ntawm cov teeb meem loj muaj xws li ua kom tawv nqaij lossis tso zis ntshav lossis ntshav khov heev. Lawv yuav xa koj mus cuag kws kho mob hauv ntshav, lossis hematologist.

Koj yuav tsum tau muaj kev ntsuas ntshav ntau ntau kom paub meej txog AIHA. Qee qhov kev ntsuas yuav ntsuas qhov ntsuas lub cev cov ntshav liab lub cev. Yog tias koj muaj AIHA, koj tus lej ntshav liab yuav tsawg. Lwm txoj kev kuaj yuav nrhiav qee yam ntawm cov ntshav. Kev kuaj ntshav uas qhia pom qhov tsis zoo ntawm lub cev tsis txaus ntawm lub qe ntshav liab uas siv tau yog qhia tias AIHA. Cov qe ntshav liab tsis txaus qhia tau hais tias lub cev tab tom sim them nyiaj rau cov qe ntshav liab uas tau ua tiav tab tom ua sai sai.

Lwm qhov kev ntsuam xyuas ntshav muaj xws li qib bilirubin ntau dua thiab ib qib qis dua ntawm cov protein hu ua haptoglobin. Bilirubin yog lub ntuj tsim los ntawm kev ua haujlwm ntawm cov ntshav liab. Cov qib no tau nce siab thaum ntau ntawm cov ntshav liab tau raug rhuav tshem. Kev kuaj ntshav haptoglobin tuaj yeem pab tau tshwj xeeb rau kev kuaj mob AIHA. Nrog rau lwm txoj kev kuaj ntshav, nws qhia tau hais tias cov protein raug rhuav tshem nrog rau cov qe ntshav liab txaus.

Muaj qee kis, cov kev ntsuas raug sim rau kev kuaj ntshav no yuav tsis txaus tshawb nrhiav kabmob AIHA, yog li koj tus kws khomob yuav tsum tau kuaj ntau dua. Lwm qhov kev ntsuam xyuas, suav nrog kev sim ncaj qha thiab tsis ncaj Coombs, tuaj yeem tshawb pom cov tshuaj tiv thaiv muaj zog hauv cov ntshav. Urinalysis thiab kev tso zis 24 teev yuav qhia cov ntshav tsis txaus hauv lub cev, xws li muaj protein ntau.

Cov kev kho mob rau IAIHA

Cov tib neeg xav tias tsam muaj mob sai sai tam sim ntawd AIHA feem ntau yuav tau mus pw hauv tsev kho mob vim nws mob siab ceev. Cov tsos mob pheej yuav tuaj yeem mus thiab tsis muaj lus piav qhia. Nws muaj peev xwm ua kom tus mob tau zoo tuaj yam tsis tau kho.

Koj tus kws kho mob yuav saib xyuas koj cov ntshav qabzib kom siab yog tias koj muaj ntshav qab zib. Mob ntshav qab zib yog qhov ua rau muaj kev phom sij txaus ntshai ntau tus neeg tuag los ntawm kev kis los ntawm kev kho mob.

Steroids

Qhov kev kho thawj zaug yog feem ntau cov tshuaj steroids xws li prednisone. Lawv yuav pab txhim kho kev suav cov qe ntshav liab. Koj tus kws kho mob yuav saib xyuas koj zoo kom saib seb cov tshuaj steriods kho tau haujlwm lawm. Thaum koj tus mob mus rau hauv kev so siab, koj tus kws kho mob yuav sim ua rau koj txiav tawm ntawm koj cov tshuaj steroids maj mam. Cov neeg mob AIHA kev kho steroid tuaj yeem xav tau cov tshuaj ntxiv thaum kho. Cov no tuaj yeem suav nrog:

• bisphosphonates
• Vitamin D
• calcium
• folic acid

Kev phais mob

Koj tus kws kho mob yuav tawm tswv yim muab tshem tawm tus po yog tias cov tshuaj steroids ua tsis tiav. Kev tshem tawm ntawm tus po tawm tuaj yeem rov qab rhuav tshem cov ntshav liab. Qhov kev phais mob no paub tias yog kev phais plab. ntawm cov neeg uas yauv mus ua txij nkawm muaj ib feem lossis tag nrho kev zam txim los ntawm lawv cov AIHA, thiab cov neeg uas muaj hom idiopathic zoo li muaj cov txiaj ntsig tau zoo tshaj plaws.

Kev tiv thaiv tshuaj

Lwm txoj kev kho mob yog cov tshuaj tiv thaiv kab mob, xws li azathioprine thiab cyclophosphamide. Cov no tuaj yeem yog cov tshuaj zoo rau cov neeg uas tsis ua tiav kev kho mob nrog cov tshuaj steroids lossis tus neeg tsis yog tus xaiv rau kev phais mob.

Qee qhov xwm txheej, cov tshuaj rituximab tuaj yeem nyiam tshaj li cov tshuaj ib txwm muaj tshuaj tiv thaiv kab mob. Rituximab yog ib qho tshuaj tiv thaiv kab mob ncaj qha tawm tsam qee cov roj ntsha muaj tseeb hauv qee cov kab mob tiv thaiv kab mob hauv lub cev.

Lub hom phiaj ncua ntev

Nws tuaj yeem nyuaj kom tau txais kev kuaj mob sai sai ntawm qhov xwm txheej no qhov tsis muaj tus yam ntxwv. Kev kho mob qee zaum qeeb nyob rau hauv cov mob no. Idiopathic AIHA tuaj yeem ua rau tuag taus yog tias tsis kho.

Idiopathic AIHA rau cov menyuam yaus yog lub sijhawm luv luv. Tus mob feem ntau mob siab rau cov neeg laus, thiab tuaj yeem flare lossis rov qab nws tus kheej yam tsis tau piav qhia. AIHA muaj kev kho tau zoo heev hauv cov neeg laus thiab menyuam yaus. Cov neeg feem coob ua kom rov zoo tag nrho.