Ibuprofen puas tuaj yeem hnyav ntxiv rau cov tsos mob ntawm COVID-19?

Zoo Siab

• Vim li cas ibuprofen paug tau tus kab mob?
• Dab tsi yog paub
• Yuav ua li cas yog tias koj muaj cov tsos mob

Kev siv Ibuprofen thiab lwm yam tshuaj tsis raws li cov tshuaj tiv thaiv kab mob (NSAIDs) thaum muaj tus mob SARS-CoV-2 yog suav tias muaj kev nyab xeeb, vim nws tsis tuaj yeem lees paub qhov kev sib raug zoo ntawm kev siv cov tshuaj no thiab kev ua tsis zoo ntawm cov pa ntawm tus mob COV KEV PAB THEM KEV THEM NTIAJ YEEM 19.

Tsis tas li ntawd, kev tshawb fawb nqa tawm hauv Ixayees ^[1] saib xyuas cov neeg mob uas siv ibuprofen rau ib lub lis piam ua ntej kuaj mob COVID-19 thiab thaum kho cov tsos mob kom zoo nrog rau cov tshuaj paracetamol thiab pom tias kev siv ibuprofen tsis cuam tshuam rau qhov mob hnyav ntxiv ntawm cov neeg mob lub chaw kho mob.

Yog li, tsis muaj pov thawj qhia tias kev siv ibuprofen tuaj yeem ua rau ntau qhov kev puas tsuaj thiab kev tuag ntawm COVID-19 thiab, yog li, kev siv cov tshuaj no yog qhia los ntawm kev noj qab haus huv, thiab yuav tsum tau siv raws li kev pom zoo los ntawm kev kho mob.

Vim li cas ibuprofen paug tau tus kab mob?

Kev tshawb fawb luam tawm hauv phau ntawv ceev xwm txheej Lancet Tshuaj Kho Mob ^[2] hais tias ibuprofen tuaj yeem ua rau cov tsos mob ntawm cov neeg muaj mob voos ua pa nyuaj, vim tias cov tshuaj no yuav ua rau muaj kev nce ntxiv ntawm ACE, uas yog cov receptor tam sim no hauv tib neeg lub hlwb thiab uas tseem khi rau tus kabmob tshiab. Cov lus tshaj tawm no yog ua raws li qhov tseeb tias cov neeg mob ntshav qab zib thiab mob ntshav siab tau ntau dua ntawm cov neeg tau txais ACE cov neeg txais, siv ibuprofen thiab lwm yam NSAIDs thiab tsim muaj COVID-19 loj.

Lwm txoj kev tshawb nrhiav nqa tawm nrog cov nas ntshav muaj zog^[3], txhawb kev siv ntawm ibuprofen rau 8 lub lis piam hauv kev noj tshuaj tsawg dua li kev pom zoo, uas ua rau muaj kev hais tawm ntau ntxiv ntawm cov leeg mob angiotensin-hloov pauv enzyme 2 (ACE2) hauv kev mob plawv.

Qhov tib yam enzyme, ACE2, zoo li yog ib qho kev nkag kis rau cov kab mob ntawm tsev neeg tus mob coronavirus hauv hlwb, thiab vim li no, qee cov kws tshawb fawb xav tias yog tias tseem muaj qhov nce ntawm cov enzyme no rau tib neeg, tshwj xeeb tshaj yog ntsws, nws muaj peev xwm hais tias tus kabmob muaj peev xwm nce sai dua, ua rau muaj cov tsos mob hnyav heev.

Dab tsi yog paub

Txawm hais tias cov kev tshawb fawb tshaj tawm txog kev sib raug zoo tsis zoo ntawm ibuprofen thiab COVID-19, Lub Koom Haum World Health thiab lwm tus neeg saib xyuas kev noj qab haus huv tau qhia tias tsis muaj pov thawj tshawb pom tias kev siv ibuprofen yuav tsis muaj kev nyab xeeb, vim tias cov txiaj ntsig tau nthuav tawm yog ua raws li kev xav thiab tsis muaj kev tshawb nrhiav tib neeg tau ua tiav lawm. Tsis tas li ntawd, qee qhov kev tshawb fawb tau taw qhia tias ^[4]:

• Tsis muaj pov thawj ncaj qha tias ibuprofen tuaj yeem cuam tshuam nrog SARS-CoV-2;
• Tsis muaj pov thawj qhia tias ibuprofen yog lub luag haujlwm rau kev ua kom qhov kev qhia tawm ntawm cov enzyme angiotensin-hloov;
• Qee qhov kev tshawb fawb hauv vitro tau qhia tias ibuprofen tuaj yeem "rhuav" ACE receptor, ua rau lub ntsej muag nyuaj ntawm cov xovtooj ntawm cov leeg-tus kab mob sib kis thiab txo qis kev pheej hmoo ntawm tus kab mob nkag mus hauv lub xov tooj ntawm txoj kev no;
• Tsis muaj pov thawj qhia tias kev siv ibuprofen tuaj yeem ua rau ntxiv lossis ua rau muaj kev pheej hmoo kis mob.

Txawm li cas los xij, kev tshawb fawb txuas ntxiv tseem xav tau kom paub tseeb tias tsis muaj kev sib raug zoo ntawm SARS-CoV-2 thiab kev siv ntawm ibuprofen lossis lwm yam NSAIDs thiab kom ntseeg tau tias kev siv zoo ntawm cov tshuaj no.

Yuav ua li cas yog tias koj muaj cov tsos mob

Yog tias muaj cov tsos mob me ntawm COVID-19, xws li ua npaws, mob hnyav hnoos thiab mob taub hau, piv txwv li, ntxiv rau kev rho tawm, nws raug nquahu kom sab laj nrog tus kws kho mob thiaj li tau txais kev qhia raws li kev siv tshuaj los kho kom rov zoo. cov tsos mob, kev siv cov paracetamol lossis ibuprofen tej zaum yuav qhia tau, uas yuav tsum tau siv raws li cov lus qhia kho mob.

Txawm li cas los xij, thaum cov tsos mob hnyav dua, thiab tej zaum yuav ua pa nyuaj thiab mob hauv siab, qhov zoo tshaj yog tus neeg mus rau hauv tsev kho mob yog li kev kuaj mob COVID-19 tuaj yeem lees paub thiab ntau yam kev kho mob tuaj yeem pib nrog lub hom phiaj los tiv thaiv lwm cov kev cuam tshuam thiab txhawb tus neeg lub neej kom zoo. Nkag siab txog kev kho mob li cas rau COVID-19.