Hypoparathyroidism: nws yog dab tsi, cov tsos mob thiab kev kho mob

Zoo Siab

• Cov tsos mob tseem ceeb
• Yuav kho tus mob li cas
• Muaj peev xwm ua rau hypoparathyroidism
• Ua rau ntawm thawj hom hypoparathyroidism
• Ua rau theem nrab hypoparathyroidism
• Ua rau pseudohypoparathyroidism

Hypoparathyroidism yog hais txog cov teeb meem ntawm cov kabmob, lossis xwm txheej, uas ua rau txo qis hauv kev nqis tes ntawm cov tshuaj HTH, tseem hu ua parathormone.

Qhov cov tshuaj hormones no yog tsim los ntawm cov roj ntsha parathyroid, uas yog 4 caj pas me me nyob tom qab cov thyroid thiab yog ib qho tseem ceeb hormone uas, ua ke nrog cov vitamin D, tswj kom muaj cov calcium nyob rau hauv cov ntshav.

Yog li, thaum tsis muaj PTH hauv lub cev, nws yog ib qho muaj los soj ntsuam qhov txo qis hauv cov calcium nyob rau hauv cov ntshav, paub hu ua hypocalcemia, uas tuaj yeem ua rau cov tsos mob xws li tsis muaj zog, mob pob txha, hloov pob txha, teeb meem mob hlwb lossis teeb meem lub siab. Kawm paub ntxiv txog hypocalcemia thiab dab tsi nws tuaj yeem ua.

Cov tsos mob tseem ceeb

Cov tsos mob ntawm hypoparathyroidism yog feem ntau cuam tshuam rau cov teeb meem uas qhov tsis ua haujlwm ntawm PTH ua rau. Yog li, qee qhov cim thiab tsos mob uas tuaj yeem tshwm sim suav nrog:

• Kev muaj zog rau cov leeg mob;
• Mob leeg pob txha;
• Nqaij tsis muaj zog lossis mob;
• General qaug dab peg;
• Lub plawv palpitations

Txij li PTH yog qhov tshuaj calcium-tswj kev ua haujlwm, thaum tsis muaj PTH txaus, calcium tsis tuaj yeem nqus mus rau hauv plab hnyuv thiab tseem muaj tshem tawm hauv cov zis, uas ua rau muaj cov calcium nyob rau hauv cov ntshav lossis hypocalcemia.

Qhov kev siv ntawm cov tsos mob yog nyob ntawm qhov mob hnyav thiab nrawm ntawm qhov poob ntawm cov calcium. Ntau tus neeg mob hypoparathyroidism yog asymptomatic, thiab tsuas yog muaj cov tsos mob thaum muaj qhov xav tau calcium ntau ntxiv hauv lub cev, xws li thaum cev xeeb tub, pub mis niam lossis siv cov tshuaj uas txo cov calcium.

Hauv ntau cov kev mob nyhav thiab mob me, kuj tseem tsis muaj tsos mob tshwm sim, thiab tus kab mob tsuas yog kuaj hauv cov kev kuaj ib txwm muaj, lossis tej zaum yuav muaj cov tsos mob me me xws li tingling thiab tsis hnov ​​nyob hauv taw, tes lossis ib ncig ntawm lub qhov ncauj.

Yuav kho tus mob li cas

Kev kho mob ntawm hypoparathyroidism muaj lub hom phiaj tseem ceeb ntawm kev tswj hwm qhov kev txo qis hauv calcium hauv lub cev, thiab yuav tsum coj los ntawm tus kws endocrinologist raws li nws qhov ua rau, mob hnyav, cov tsos mob thiab cov ntshav calcium calcium ntau ntau.

Thaum cov calcium qib qis heev, qis dua 7.5mg / dl, cov mob ntshav qab zib ntau heev tshwm sim thiab, hauv cov xwm txheej no, kev kho mob hauv tsev kho mob yog qhov tsim nyog, nrog calcium hloov ncaj qha rau hauv cov hlab ntsha, nrog calcium gluconate.

Thaum hypocalcemia yog mob me thiab mob ntev, kev kho mob yog hloov hloov calcium thiab vitamin D ntawm qhov ncauj. Magnesium yuav pab txhawb qhov tsim tawm ntawm PTH thiab, yog li ntawd, tuaj yeem pab tau, tshwj xeeb tshaj yog thaum nws qib qis kuj tsawg. Lwm txoj kev kho mob, xws li thiazide diuretics los yog hloov pauv ntawm PTH pom zoo, yuav qhia los ntawm tus kws endocrinologist, nyob ntawm txhua kis.

Muaj peev xwm ua rau hypoparathyroidism

Hypoparathyroidism tuaj yeem faib ua 2 hom loj, nyob ntawm cov laj thawj uas ua rau kom tsis muaj qhov cuam tshuam ntawm PTH:

• Thawj hypoparathyroidism: tshwm sim thaum tsim ntawm PTH raug cuam tshuam vim tias cov qog muaj teeb meem lossis tau raug tshem tawm.
• Thib ob hypoparathyroidism: yog thaum muaj qee qhov kev tawm dag zog, xws li cov tshuaj magnesium tsawg, ua rau cov qog ua PTH tsawg dua yam tsis muaj teeb meem hauv lawv.

Kuj tseem muaj qhov xwm txheej thib peb, uas yog hu ua pseudo-hypoparathyroidism, uas tshwm sim hauv cov kab mob muaj keeb, uas yog, uas dhau los ntawm tsev neeg caj ces, los ntawm niam txiv mus rau menyuam, thiab uas nce tsis kam rau hauv cov kabmob uas cov tshuaj hormones yuav tsum ua. Yog li, qhov tshuaj hormones tsis tuaj yeem ua nws txoj haujlwm txawm tias nws tau tsim nyob rau hauv ntau ntau los ntawm cov qog parathyroid.

Ua rau ntawm thawj hom hypoparathyroidism

Hom no tshwm sim feem ntau vim yog kev tshem tawm cov qog ua kab mob parathyroid, piv txwv li kev kho mob hyperparathyroidism, piv txwv li, tab sis nws kuj tuaj yeem tshwm sim vim kev raug mob los ntawm qog parathyroid qog. Qhov xwm txheej no tshwm sim thaum kev phais mob raug ua tiav ntawm caj dab thaj tsam, uas yog lub qog, rau mob qog nqaij hlav lossis pob taub. Raws li cov qauv tau ze heev thiab cov qog tau me me heev, qee zaum nws nyuaj rau kev txheeb xyuas thiab cais lawv los ntawm lwm cov qauv. Kuaj xyuas thaum koj tshem tawm cov qog tsim nyog thiab qhov ua kom rov zoo li cas.

Ua rau theem nrab hypoparathyroidism

Hom hypoparathyroidism no feem ntau ua rau muaj kev tsis haum lub zog magnesium tsis tu ncua.

Txawm hais tias lub cev tsis muaj zog magnesium tuaj yeem txhawb qhov tsim tau ntawm PTH, thaum lub magnesium qis heev, thiab tau ntev, nws xa xov mus rau parathyroid kom tsis tsim PTH ntau dua thiab tseem ua rau cov kabmob ua rau lub cev tsis txaus siab rau qhov tshuaj hormones, yog li nws tsis tuaj yeem ua, ua rau hypoparathyroidism.

Ua rau pseudohypoparathyroidism

Pseudo-hypoparathyroidism yog hais txog cov kab mob uas hloov caj ces, feem ntau los ntawm caj ces, ua rau lub cev nqaij mos ua rau tsis txaus ntseeg ntawm PTH. Muaj 3 hom pseudohypoparathyroidism, nyob ntawm seb lawv puas cuam tshuam nrog cov kab mob uas tsis tshua muaj npe hu ua Albright cov keeb tiv thaiv osteodystrophy thiab hom PTH tsis kam uas yog tshwm sim los.

Kev teb rau qhov tsis muaj kev ua ntawm PTH, cov qog nce ntau thiab sim ua PTH ntau, nrog PTH ib txwm los sis siab tshaj nyob rau hauv cov ntshav, tab sis PTH no tsis tuaj yeem ua. Yog li no, cov duab kho mob yog tib yam li ntawm hypoparathyroidism, nws zoo li yog tias yam tshuaj no tsis muaj nyob. Yog li, nws tsis tuaj yeem hu ua hypoparathyroidism ib txwm, vim tias hauv kev muaj tiag cov qib PTH khiav ceev yog ib txwm lossis nce dua, raug hu ua pseudo-hypoparathyroidism, uas txhais tau tias "zoo ib yam li hypoparathyroidism".