Glucagonoma

Zoo Siab

• Cov tsos mob ntawm Glucagonoma yog dab tsi?
• Cov Kab Mob Glucagonoma Yog Dab Tsi?
• Yuav kuaj li cas thiaj paub hais tias Cov Mob Hlob Glucagonoma?
• Muaj Tshuaj Dab Tsi Kho Rau Glucagonoma?
• Cov Teeb Meem Ntawm Glucagonoma Yog Dab Tsi?
• Kuv tuaj yeem cia siab dab tsi hauv Lub Sijhawm Ntev?

Glucagonoma yog dab tsi?

Glucagonoma yog ib qho mob qog ua hlav nrog rau tus txiav. Glucagon yog yam tshuaj tsim los ntawm cov txiav ua haujlwm nrog insulin los tswj cov piam thaj hauv koj cov ntshav. Glucagonoma qog cov hlwb ua cov ntau ntawm glucagon, thiab cov qib siab no tsim cov tsos mob hnyav, mob, thiab ua rau muaj sia nyob. Li thaj tsam 5 txog 10 feem pua ​​ntawm cov hlav hlav neuroendocrine uas tshwm sim hauv lub qog nqaij hlav yog glucagonomas.

Cov tsos mob ntawm Glucagonoma yog dab tsi?

Yog tias koj muaj cov qog ntshav uas ua rau ntau ntau ntawm glucagon, nws yuav cuam tshuam rau ntau yam ntawm koj lub cev. Glucagon sib npaug rau cov teebmeem ntawm insulin los ntawm kev tswj hwm cov piam thaj hauv koj cov ntshav. Yog tias koj muaj cov piam thaj ntau dhau, koj lub hlwb tsis tso cov piam thaj thiab tso cov piam thaj hauv koj cov hlab ntshav.

Glucagonoma ua rau cov tsos mob zoo li ntshav qab zib thiab lwm cov tsos mob uas txaus ntshai thiab txaus ntshai, suav nrog:

• ntshav qab zib kom ntau
• ntev li ntawm nqhis dej thiab kev tshaib nqhis vim muaj ntshav qab zib
• nquag waking thaum hmo ntuj tso zis
• zawv plab
• xoo pob khaus tawv nqaij, los yog ua pob khaus rau ntawm lub ntsej muag, plab, pob tw, thiab ko taw uas feem ntau sawv los yog muaj kua paug
• tsis poob ceeb thawj phaus
• ntshav txhaws nyob rau hauv ob txhais ceg, uas kuj hu ua kev sib zog ua leeg ntshav txhaws

Cov Kab Mob Glucagonoma Yog Dab Tsi?

Tsis muaj qhov paub tias yog vim li cas ntawm glucagonoma. Yog tias koj muaj tsev neeg muaj keeb kwm muaj mob hu ua endocrine neoplasia type 1 (MEN1) koj muaj feem ntau yuav muaj mob glucagonoma. Txawm li cas los xij, cov uas tsis muaj lwm yam kev phom sij tuaj yeem tsim cov qog no.

Glucagonomas yog mob qog noj ntshav, lossis mob siab, txog lub sijhawm. Malignant glucagonomas kis mus rau lwm cov ntaub so ntswg, feem ntau yog lub siab, thiab pib cuam tshuam nrog kev ua haujlwm ntawm lwm yam kabmob.

Yuav kuaj li cas thiaj paub hais tias Cov Mob Hlob Glucagonoma?

Nws tuaj yeem nyuaj rau kev kuaj ntshav qab zib. Feem ntau, cov tsos mob tshwm sim los ntawm lwm qhov mob, thiab nws yuav yog ntau xyoo ua ntej kev kuaj mob raug kuaj pom.

Kev kuaj mob yog pib ua nrog ntau qhov kev kuaj ntshav. Cov qib glucagon nce siab yog qhov pom ntawm tus mob no. Lwm yam cim muaj xws li cov ntshav qab zib, cov ntshav siab ntau ntawm chromogranin A, uas yog cov protein feem ntau pom muaj nyob hauv qog carcinoid, thiab ntshav liab, uas yog ib yam mob uas koj muaj cov ntshav liab tsawg.

Koj tus kws kho mob yuav ua raws li cov kev kuaj mob no nrog CT scan ntawm lub plab mog txhawm rau saib seb puas muaj cov qog.

Ob feem peb ntawm tag nrho cov glucagonomas yog malignant. Cov hlav no yuav kis thoob plaws lub cev thiab yuav ua rau lwm cov plab hnyuv siab raum. Cov qog feem ntau loj thiab tuaj yeem yog 4 rau 6 centimeters dav thaum lawv nrhiav tau. Tus mob khees xaws no feem ntau tsis pom txog thaum nws kis mus rau nplooj siab.

Muaj Tshuaj Dab Tsi Kho Rau Glucagonoma?

Kev kho glucagonoma cuam tshuam txog kev tshem tawm cov qog thiab kho cov kev cuam tshuam ntawm kev tshaj tawm ntawm glucagon rau koj lub cev.

Nws yog qhov zoo tshaj los pib kho los ntawm kev ua kom lub zog ntawm cov piam thaj ntau dhau. Qhov no feem ntau koom nrog kev noj tshuaj somatostatin analog tshuaj, xws li kev txhaj tshuaj octreotide (Sandostatin). Octreotide pab tawm tsam cov teebmeem ntawm glucagon rau koj cov tawv nqaij thiab txhim kho pob khaus tawv nqaij.

Yog tias koj tau poob qhov hnyav lawm, koj yuav tsum tau tso ib txoj IV mus pab koj lub cev hnyav. Mob ntshav qab zib tuaj yeem kho tau los ntawm cov tshuaj insulin thiab kev saib xyuas koj cov ntshav qabzib kom ntau.

Koj tuaj yeem yuav muab cov tshuaj tiv thaiv kev tsis haum tshuaj, lossis ua kom ntshav txawv. Qhov no txwv tsis pub tsim cov ntshav txhaws hauv koj ob txhais ceg, tseem paub tus mob ntshav thim ntshav. Rau cov tib neeg muaj kev pheej hmoo ntawm txoj hlab ntsws sib sib zog nqus, lim yuav tso rau hauv ib qho ntawm koj cov leeg ntshav loj, qis qis ntshav qab ntsev, txhawm rau txhawm rau txhawm rau tiv thaiv cov ntshav txhaws kom mus txog koj lub ntsws.

Thaum koj muaj kev noj qab nyob zoo, lub qog yuav raug phais. Hom qog no tsis tshua pom zoo rau kev siv tshuaj kho. Kev phais mob ua tau zoo tshaj yog tias lub qog raug ntes thaum nws tseem ua kom txiav siab mob rau txiav.

Kev phais mob ntawm lub plab yuav ua tau laparoscopically, nrog rau kev txiav me me kom pom zoo rau cov koob yees duab, cov teeb, thiab cov cuab yeej, lossis los ntawm kev tsim cov kev qhib loj dua.

Feem ntau cov glucagonomas tshwm sim nyob rau sab laug los yog tw ntawm qhov txiav ua ke. Kev tshem tawm ntawm ntu no yog hu ua distal pancreatectomy. Hauv qee cov neeg, tus po kuj raug tshem tawm thiab. Thaum kuaj cov qog nqaij hlav tawm hauv qab lub tshuab tsom kab, nws yog qhov nyuaj rau qhia seb nws puas muaj mob qog nqaij hlav. Yog tias nws mob qog nqaij hlav, koj tus kws phais yuav tshem tawm cov qog ntau npaum li uas tiv thaiv kom nws mus tsis tau ntxiv. Qhov no tuaj yeem suav nrog qee feem ntawm tus txiav ua kab mob ntshav ntswg, ntshav nyob hauv lub zos, thiab qee lub siab.

Cov Teeb Meem Ntawm Glucagonoma Yog Dab Tsi?

Ntau dhau glucagon ua rau cov tsos mob zoo li ntshav qab zib. Ntshav qab zib siab tuaj yeem ua rau:

• leeg puas tsuaj
• dig muag
• teeb meem metabolic
• mob hlwb

Txoj hlab ntsws sib sib zog nqus tuaj yeem ua rau cov ntshav txhaws mus rau hauv lub ntsws, thiab nws tseem tuaj yeem ua rau tuag taus.

Yog tias cov qog tawm tsam lub siab, thaum kawg nws tuaj yeem ua rau lub siab ua haujlwm.

Kuv tuaj yeem cia siab dab tsi hauv Lub Sijhawm Ntev?

Feem ntau, los ntawm lub sijhawm kuaj glucagonoma kuaj, tus mob cancer tau kis mus rau lwm yam kabmob, xws li daim siab. Feem ntau, kev phais mob pab tsis tau vim hais tias nws nyuaj rau tshawb nrhiav tau ntxov.

Thaum ib lub qog tshem tawm, cov nyhuv ntawm cov ntau tshaj glucagon txo qis sai li sai tau. Yog hais tias cov qog tsuas txwv cov leeg nqaij hlav xwb, tsib xyoos kev muaj sia nyob yog, txhais tau tias 55 feem pua ​​ntawm tib neeg nyob rau tsib xyoos tom qab kev phais mob.Muaj li tsib xyoo ntawm kev muaj sia nyob yog tias cov qog ntshav tsis tuaj yeem raug tshem tawm los ntawm kev phais mob.