Acromegaly thiab gigantism: cov tsos mob, ua rau thiab kho

Zoo Siab

• Cov tsos mob tseem ceeb
• Dab tsi yog cov nyom
• Yuav ua li cas kom paub meej tias kuaj mob
• Yuav kho tus mob li cas

Gigantism yog ib qho mob tsis tshua muaj tsawg hauv lub cev tsim tawm ntau dhau ntawm kev loj hlob hormone, uas feem ntau yog vim muaj cov qog nqaij hlav ua paug hauv lub caj pas pituitary, paub tias pituitary adenoma, ua rau cov kabmob thiab qhov chaw ntawm lub cev loj dua li ib txwm muaj.

Thaum tus kab mob tshwm sim thaum yug los, nws yog lub npe hu ua gigantism, txawm li cas los xij, yog tias tus kabmob tshwm sim rau cov neeg laus, feem ntau ncig ntawm lub hnub nyoog 30 lossis 50 xyoo, nws yog lub npe hu ua acromegaly.

Hauv ob qho tib si, tus kab mob no tshwm sim los ntawm qhov hloov pauv ntawm lub qog pituitary, qhov chaw nyob ntawm lub hlwb uas ua rau kev loj hlob hormone, thiab yog li kev kho mob yog ua kom txo qis cov tshuaj hormone ntau lawm, uas tuaj yeem ua los ntawm kev phais, kev siv tshuaj kho mob lossis hluav taws xob, muab ua piv txwv.

Cov tsos mob tseem ceeb

Cov neeg laus uas muaj acromegaly lossis cov menyuam yaus gigantism feem ntau muaj qhov loj dua li cov tes, taw thiab daim di ncauj, nrog rau lub ntsej muag zoo nkauj. Ib qho ntxiv, kev loj hlob loj dhau los kuj tseem tuaj yeem ua rau:

• Tawv lossis hlawv rau hauv tes thiab taw;
• Qabzib ntau dhau hauv cov ntshav;
• Kev kub siab;
• Mob thiab o ntawm cov pob qij txha;
• Ob lub zeem muag;
• Txhawb nqa;
• Hloov pauv chaw;
• Cov lus hais kev loj hlob;
• Ntxaib Ntxub;
• Kev coj khaub ncaws tsis xwm yeem;
• Nkees dhau heev lawm.

Tsis tas li ntawd, raws li muaj qhov ua tau tias kev loj hlob hormone ntau dhau los yog tsim los ntawm qog benign nyob rau hauv lub caj pas pituitary, lwm cov tsos mob xws li mob taub hau tsis tu ncua, teeb meem tsis pom kev lossis txo qis kev sib deev, piv txwv li, kuj tseem yuav tshwm sim.

Dab tsi yog cov nyom

Qee qhov teeb meem uas qhov kev hloov kho no tuaj yeem nqa mus rau tus neeg mob yog:

• Ntshav Qab Zib;
• Pw tsaug zog apnea;
• Pluag tsis pom kev;
• Nce lub plawv loj;

Vim tias qhov txaus ntshai ntawm cov teeb meem no, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib kws kho mob yog tias koj xav tias muaj tus kab mob no lossis hloov pauv.

Yuav ua li cas kom paub meej tias kuaj mob

Thaum muaj kev xoom xaim ntawm kev xav gigantism, yuav tsum kuaj ntshav ntsuam xyuas qib IGF-1, muaj protein ntau ntxiv thaum cov qib kev loj hlob hormone tseem siab dua qub, qhia tias acromegaly lossis gigantism.

Tom qab kuaj mob, tshwj xeeb tshaj yog hais rau cov neeg loj, kuaj CT kuj tseem yuav raug txiav txim, piv txwv li, txhawm rau txheeb xyuas yog tias muaj qog nyob hauv lub caj pas pituitary uas tuaj yeem hloov nws txoj haujlwm. Hauv qee kis, tus kws kho mob tuaj yeem xaj ntsuas qhov ntsuas ntawm kev loj hlob hormone ntau.

Yuav kho tus mob li cas

Kev kho ntawm gigantism nws txawv raws li dab tsi yog ua rau kev loj hlob ntau dhau lawm. Yog li, yog tias muaj cov qog ntshav hauv lub caj pas pituitary, feem ntau nws pom zoo kom muaj kev phais kom tshem tawm cov qog thiab rov qab tsim cov tshuaj hormones kom yog.

Txawm li cas los xij, yog tias tsis muaj lub laj thawj rau kev hloov pauv hloov los sis yog tias qhov phais tsis ua haujlwm, tus kws kho mob tsuas yog qhia txog kev siv hluav taws xob lossis tshuaj noj, xws li somatostatin analogs lossis dopamine agonists, piv txwv li, uas yuav tsum tau siv thaum lub sijhawm muaj sia nyob ntev. txhawm rau kom tswj kev sib deev theem.