Enbrel vs. Humira rau Mob Pob Kws Ntaus: Sab Nraum Los Sib Piv
Zoo Siab
- Txheej txheem cej luam
- Cov hauv paus ntawm Enbrel thiab Humira
- Tshuaj yeeb tshuaj ib sab
- Tshuaj cia
- Tus nqi, muaj, thiab kev tuav pov hwm
- Sab sij huam
- Cov tshuaj sib cuam tshuam
- Siv nrog lwm yam mob
- Tham nrog koj tus kws kho mob
Txheej txheem cej luam
Yog tias koj muaj mob pob qij txha (RA), koj txhua tus yuav tsum paub txog qhov mob thiab mob caj dab uas tuaj yeem ua rau tuaj yeem sawv saum txaj thaum sawv ntxov.
Enbrel thiab Humira yog ob yam tshuaj uas yuav pab tau. Saib nrog rau cov tshuaj no ua li cas thiab seb lawv khaws khoom sib txawv li cas.
Cov hauv paus ntawm Enbrel thiab Humira
Enbrel thiab Humira yog cov tshuaj uas siv los kho RA.
Ob qho tshuaj no yog cov kabmob necrosis factor (TNF) alpha inhibitors. TNF alpha yog protein ua los ntawm koj lub cev tiv thaiv kab mob. Nws muaj feem xyuam rau o thiab kev sib koom ua ke.
Enbrel thiab Humira thaiv qhov kev txiav txim ntawm TNF alpha uas ua rau kev puas tsuaj los ntawm cov leeg tsis zoo.
Cov lus qhia tam sim no tsis pom zoo kom TNF inhibitors yog thawj txoj kev kho rau RA. Hloov chaw, lawv pom zoo kom kho nrog DMARD (xws li methotrexate).
Dhau li RA, ob Enbrel thiab Humira kuj kho:
- raws li cov leeg mob ntsws (JIA)
- mob caj dab psoriatic (PsA)
- ankylosing spondylitis
- cov quav hniav psoriasis
Tsis tas li ntawd, Humira tseem kho:
- Crohn tus kab mob
- mob ncauj plab (UC)
- hidradenitis suppurativa, tawv nqaij mob
- uveitis, mob hauv qhov muag
Tshuaj yeeb tshuaj ib sab
Enbrel thiab Humira ua haujlwm zoo ib yam rau kev kho RA, thiab ntau yam ntawm lawv lub ntsej muag zoo ib yam.
Cov lus qhia tsis txhob hais qhia qhov kev nyiam rau TNF inhibitor tshaj lwm tus, vim yog tsis muaj pov thawj txaus ntseeg tias ib qho muaj txiaj ntsig dua qhov tsis zoo.
Qee tus neeg tau txais txiaj ntsig los ntawm kev hloov mus rau lwm qhov tshuaj tiv thaiv TNF yog tias thawj zaug tsis ua haujlwm, tab sis feem ntau tus kws kho mob xav kom hloov mus rau lwm cov tshuaj RA sib txawv.
Cov lus hauv qab no yog cov ntsiab lus ntawm ob hom tshuaj no:
Enbrel | Humira | |
Lub npe li cas ntawm cov tshuaj no? | etanercept | adalimumab |
Puas yog ib txwm muaj? | tsis muaj | tsis muaj |
Daim ntawv no cov tshuaj twg tuaj? | txhaj tshuaj | txhaj tshuaj |
Cov tshuaj no dab tsi muaj zog? | • 50-mg / mL ib leeg-siv prefilled koob txhaj tshuaj • 50-mg / mL ib zaug-cov tshuaj noj ua ntej SureClick Autoinjector • 50-mg / mL ib leeg-muab tshuaj lub taub hau cartridge rau kev siv nrog AutoTouch autoinjector • 25-mg / 0.5 mL ib leeg-siv prefilled koob txhaj tshuaj • 25-mg ntau-koob vial | • 80-mg / 0.8 mL ib-xaum siv los ua tus cwj mem • 80-mg / 0.8 mL ib leeg-siv prefilled koob txhaj tshuaj • 40-mg / 0.8 mL ib-xaum siv los ua tus cwj mem • 40-mg / 0.8 mL ib leeg-siv prefilled koob txhaj tshuaj • 40-mg / 0.8 mL ib leeg-siv vial (siv tsev kho mob nkaus xwb) • 40-mg / 0.4 mL ib-xaum siv los ua tus cwj mem • 40-mg / 0.4 mL ib leeg-siv prefilled koob txhaj tshuaj • 20-mg / 0.4 mL ib leeg-siv prefilled koob txhaj tshuaj • 20-mg / 0.2 mL ib leeg-siv prefilled koob txhaj tshuaj • 10-mg / 0.2 mL ib leeg-siv prefilled koob txhaj tshuaj • 10-mg / 0.1 mL ib leeg-siv prefilled koob txhaj tshuaj |
Cov tshuaj no ib txwm muaj npaum li cas? | ib zaug ib as thiv | ib zaug ib as thiv twg lossis ib zaug txhua lwm lub lim tiam |
Koj tuaj yeem pom tias Enbrel SureClick Autoinjector thiab Humira prefilled cwjmem yog qhov yooj yim dua thiab siv tau yooj yim dua li lub koob txhaj tshuaj tiv thaiv kab mob. Lawv yuav tsum muaj ob peb kauj ruam.
Cov neeg feem ntau yuav pom qee cov txiaj ntsig ntawm kev siv tshuaj tom qab 2 rau 3 koob tshuaj, tab sis kev sim txaus ntawm cov tshuaj muaj li 3 hlis pom lawv cov txiaj ntsig tag nrho.
Yuav ua li cas txhua tus neeg teb rau ib qho yeeb tshuaj yuav sib txawv.
Tshuaj cia
Enbrel thiab Humira muab khaws cia zoo ib yam nkaus.
Ob qho tib si yuav tsum khaws cia rau hauv daim ntawv me me kom tiv thaiv teeb meem lossis teeb meem lub cev. Lwm cov lus qhia cia yog pom hauv qab no:
- Khaws cov tshuaj hauv lub tub yees rau qhov txias li 36 ° F thiab 46 ° F (2 ° C thiab 8 ° C).
- Yog hais tias mus ncig, khaws cov tshuaj nyob rau hauv chav tsev kub (68-77 ° F lossis 20-25 ° C) mus txog 14 hnub.
- Tiv thaiv cov tshuaj ntawm lub teeb thiab vaum.
- Tom qab 14 hnub ntawm chav sov, muab cov tshuaj pov tseg. Tsis txhob muab tso rau hauv tub yees.
- Tsis txhob tso cov tshuaj lossis siv yog tias nws tau khov thiab tom qab yaj.
Tus nqi, muaj, thiab kev tuav pov hwm
Enbrel thiab Humira tsuas muaj raws li muaj koob npe tshuaj, tsis muaj cov tshuaj tua kab mob, thiab lawv raug nqi txog ib yam.
Lub vev xaib GoodRx tuaj yeem muab koj ib lub tswv yim xav paub ntxiv txog lawv cov nqi tam sim no, tus nqi pes tsawg.
Ntau lub chaw fajseeb khomob yuavtsum tau kev tsocai uantej los ntawm koj tus kws khomob uantej lawv yuav them thiab them rau yam tshuaj no ib yam nkaus. Txheeb xyuas koj lub tuam txhab kev pov hwm lossis tsev muag tshuaj seb koj puas xav tau ntawv tso cai ua ntej rau Enbrel lossis Humira.
Koj lub tsev muag tshuaj tuaj yeem pab koj rau cov ntawv yog tias xav tau kev tso cai.
Feem ntau cov chaw muag tshuaj nqa ob qho tag nrho Enbrel thiab Humira. Txawm li cas los xij, nws yog ib lub tswv yim zoo hu rau koj lub chaw muag tshuaj ua ntej kom paub tseeb tias koj cov tshuaj yog hauv Tshuag.
Biosimilars muaj rau ob qho tshuaj. Thaum lawv dhau los ua muaj, biosimilars yuav tuaj yeem pheej yig dua li cov tshuaj lag luam tshuaj lub npe.
Lub biosimilar ntawm Enbrel yog Erelzi.
Ob lub biosimilars ntawm Humira, Amjevita thiab Cyltezo, tau pom zoo los ntawm U.S. Food and Drug Administration (FDA). Txawm li cas los xij, tsis muaj tam sim no rau kev yuav khoom hauv Tebchaws Meskas.
Amjevita tau dhau los ua lag luam nyob hauv Europe xyoo 2018, tab sis nws tsis xav tias yuav ntaus lub Tebchaws Asmeskas cov lag luam kom txog thaum 2023.
Sab sij huam
Enbrel thiab Humira koom nrog tib chav kawm tshuaj. Vim li ntawd, lawv muaj kev phiv zoo sib xws.
Qee qhov kev phiv ntau tshaj suav nrog:
- cov tshuaj tiv thaiv ntawm qhov chaw txhaj tshuaj
- mob sinus tau
- mob taub hau
- ua pob
Cov kev mob tshwm sim hnyav heev tuaj yeem suav nrog:
- muaj feem yuav mob qog noj ntshav
- cov teeb meem hlab ntsha hlwb
- ntshav muaj teeb meem
- tshiab lossis ua tsis zoo rau lub plawv tsis ua haujlwm
- psoriasis tshiab lossis ntog tsis zoo
- kev fab tshuaj tsis haum
- autoimmune kev tsis haum
- mob hnyav
- kev tiv thaiv ntawm lub cev tsis muaj zog
Ib ntawm 177 tus neeg tau pom tias adalimumab, lossis Humira, cov neeg siv tau tshaj li peb zaug xws li tshaj tawm tias qhov kev txhaj tshuaj / infusion-site hlawv thiab ua plev tom qab rau lub hlis ntawm kev kho mob.
Cov tshuaj sib cuam tshuam
Nco ntsoov qhia koj tus kws kho mob paub txog txhua yam tshuaj, vitamins lossis tshuaj ntsuab uas koj tau noj. Qhov no tuaj yeem pab koj tus kws kho mob tiv thaiv kev sib txuam tshuaj, uas tuaj yeem hloov txoj kev ua haujlwm ntawm koj cov tshuaj.
Kev sib cuam tshuam tuaj yeem tsim kev puas tsuaj lossis tiv thaiv cov tshuaj ua haujlwm tau zoo.
Enbrel thiab Humira cuam tshuam nrog qee cov tshuaj qub. Siv Enbrel lossis Humira nrog cov tshuaj tiv thaiv thiab tshuaj hauv qab no ua rau koj muaj feem kis mob yooj yim dua:
- Nyob txhaj tshuaj tiv thaiv, xws li:
- varicella thiab varicella zoster (qhua dej qhua qaib) cov tshuaj tiv thaiv
- Tshuaj tiv thaiv herpes zoster (shingles) tshuaj tiv thaiv
- FluMist, ib qho tshuaj tsuag rau qhov ua npaws
- Tshuaj tiv thaiv qhua pias, mob pob qog, thiab rubella (MMR)
- tshuaj siv los txhawm rau tiv thaiv koj lub cev tiv thaiv kab mob xws li anakinra (Kineret) lossis abatacept (Orencia)
- Qee yam tshuaj tua kab mob cancer, xws li cyclophosphamide thiab methotrexate
- Qee lwm lwm yam tshuaj RA xws li sulfasalazine
- Qee cov tshuaj uas ua los ntawm cov protein hu ua cytochrome p450, suav nrog:
- warfarin (Coumadin)
- cyclosporine (Neoral, Sandimmune)
- theophylline
Siv nrog lwm yam mob
Yog tias koj muaj kab mob siab hom B, noj Enbrel lossis Humira tuaj yeem ua kom koj kis tau. Qhov no txhais tau tias koj yuav pib muaj cov tsos mob siab B, xws li:
- nkees
- tsis qab los noj mov
- Qhov muag daj ntawm koj cov tawv nqaij lossis ntsiab muag ntawm koj lub qhov muag
- mob sab xis xis koj lub plab
Kev kis tus mob tseem tuaj yeem ua rau daim siab ua tsis tau thiab tuag. Koj tus kws kho mob yuav kuaj koj cov ntshav kom ntseeg tau tias koj tsis muaj kab mob siab B ua ntej koj tau txais ib yam ntawm cov tshuaj no.
Tham nrog koj tus kws kho mob
Enbrel thiab Humira yog cov tshuaj zoo heev. Lawv tau zoo tib yam nkaus ntawm kev txo cov tsos mob ntawm RA.
Txawm li cas los xij, muaj qee qhov sib txawv me ntsis, qee qhov yuav ua rau ib qho yooj yim dua rau koj siv.
Piv txwv li, Humira tuaj yeem noj txhua lwm lub lim tiam lossis txhua asthiv, thaum Enbrel tsuas tuaj yeem noj ib asthiv.Koj kuj tseem yuav pom tias koj nyiam qee tus neeg thov nkag ua haujlwm, xws li cwjmem lossis kho tsheb. Qhov kev xaiv ua ntej ntawd yuav txiav txim siab saib koj xaiv hom tshuaj twg.
Paub me ntsis ntxiv txog ob yam tshuaj no tuaj yeem pab koj tham nrog koj tus kws kho mob kom paub seb ob leeg puas yog qhov kev xaiv rau koj.