Cov Kev Kho Mob RA: DMARDs thiab TNF-Alpha Tus Neeg Tiv Thaiv

Zoo Siab

• Taw qhia
• DMARDs: Qhov tseem ceeb hauv kev kho thaum ntxov
• DMARDs nrog cov tshuaj pleev xim
• Corticosteroids
• Cov NSAIDs Tuaj Muag
• Tshuaj NSAIDs
• DMARDs thiab kis tau tus mob
• TNF-alpha inhibitors
• Tham nrog koj tus kws kho mob
• Q:
• A:

Taw qhia

Mob caj dab mob ntsws (RA) yog ib qho kev kho mob autoimmune ntev. Nws ua rau koj lub cev tiv thaiv tsis zoo rau cov nqaij noj qab nyob zoo hauv koj cov pob qij txha, ua rau mob, o, thiab txhav. Tsis zoo li osteoarthritis, uas tshwm sim los ntawm kev coj thiab kua muag thaum koj hnub nyoog, RA tuaj yeem cuam tshuam leej twg thaum muaj hnub nyoog li cas. Tsis muaj leej twg paub tseeb tias dab tsi ua rau nws.

RA tsis muaj tshuaj kho tau, tab sis tshuaj muaj peev xwm pab txo kev mob tshwm sim. Cov tshuaj no suav nrog kev siv tshuaj tiv thaiv, corticosteroids, thiab cov tshuaj uas tiv thaiv lub cev tsis muaj zog. Qee qhov zoo tshaj plaws ntawm kev siv tshuaj kho mob yog kev hloov kho kab mob los tiv thaiv rheumatic (DMARDs), uas suav nrog TNF-alpha inhibitors.

DMARDs: Qhov tseem ceeb hauv kev kho thaum ntxov

DMARDs yog cov tshuaj uas kws kho mob rheumatologist feem ntau muab tshuaj tom qab kev kuaj mob ntawm RA. Ntau yam kev puas tsuaj sib koom tes los ntawm RA tshwm sim hauv thawj ob xyoos, yog li cov tshuaj no tuaj yeem ua rau muaj kev cuam tshuam loj thaum ntxov nyob rau hauv chav kawm ntawm tus mob.

DMARD ua haujlwm los ntawm kev ua kom tsis muaj zog ntawm koj lub cev. Qhov kev txiav txim no txo ​​RA qhov kev tawm tsam ntawm koj cov pob qij txha txhawm rau kom tsawg dua qhov kev puas tsuaj tag nrho.

Piv txwv ntawm DMARDs suav nrog:

• methotrexate (Otrexup)
• hydroxychloroquine (Plaquenil)
• leflunomide (Arava)

DMARDs nrog cov tshuaj pleev xim

Qhov poob qis hauv kev siv DMARDs yog qhov lawv qeeb qeeb ua. Nws tuaj yeem siv sij hawm ntau lub hlis kom hnov ​​mob hnov ​​mob los ntawm DMARD. Vim li no, tus kws kho mob rheumatologist feem ntau hais kom ua kom sai li sai tau xws li corticosteroids lossis nonsteroidal anti-inflammatory tshuaj (NSAIDs) noj tib lub sijhawm. Cov tshuaj no tuaj yeem pab txo qhov mob thaum koj tseem tos DMARD kom siv tau.

Piv txwv ntawm corticosteroids lossis NSAIDs uas yuav siv nrog DMARDs suav nrog:

Corticosteroids

• prednisone (Rayos)
• methylprednisolone (Depo-Medrol)
• triamcinolone (Aristospan)

Cov NSAIDs Tuaj Muag

• tshuaj aspirin
• ibuprofen
• naproxen sodium

Tshuaj NSAIDs

• nabumetone
• celecoxib (Celebrex)
• piroxicam (Feldene)

DMARDs thiab kis tau tus mob

DMARDs cuam tshuam koj tag nrho kev tiv thaiv kab mob. Qhov no txhais tau tias lawv ua rau koj muaj kev pheej hmoo kis tus mob tsawg dua.

Feem ntau kev kis mob uas cov neeg mob RA muaj:

• tawv nqaij kis kab mob
• sab saud mob ntsws
• mob ntsws o
• mob txeeb zig

Txhawm rau pab tiv thaiv kev kis mob, koj yuav tsum xyaum tu cev kom huv si, suav nrog kev ntxuav tes txhua zaus thiab da dej txhua hnub lossis txhua hnub. Koj kuj yuav tsum nyob nrug ntawm cov neeg muaj mob.

TNF-alpha inhibitors

Tumor necrosis factor alpha, lossis TNF alpha, yog ib yam khoom uas tshwm sim hauv koj lub cev. Hauv RA, lub nruab zog tiv thaiv kabmob hlwb uas tawm tsam cov pob qij txha tsim cov theem siab dua ntawm TNF alpha. Cov qib siab no ua rau mob thiab o. Thaum ob peb lwm yam ntxiv rau RA kev puas tsuaj nyob rau hauv cov pob qij txha, TNF alpha yog tus neeg ua haujlwm tseem ceeb hauv cov txheej txheem.

Vim tias TNF alpha yog qhov teeb meem zoo li no hauv RA, TNF-alpha inhibitors yog ib qho tseem ceeb ntawm DMARDs ntawm cov lag luam tam sim no.

Muaj tsib hom TNF-alpha inhibitors:

• adalimumab (Humira)
• etanercept (Enbrel)
• certolizumab pegol (Cimzia)
• golimumab (Simponi)
• infliximab (Nco)

Cov tshuaj no tseem hu ua TNF-alpha blockers vim tias lawv thaiv kev ua haujlwm ntawm TNF alpha. Lawv txo TNF alpha ntau ntau hauv koj lub cev los pab txo cov tsos mob RA. Lawv kuj tseem yuav pib ua haujlwm nrawm dua li lwm lub DMARD. Lawv pib siv tau li ob lub hlis mus rau ib hlis.

Tham nrog koj tus kws kho mob

Feem ntau cov neeg muaj RA teb zoo rau TNF-alpha inhibitors thiab lwm yam DMARDs, tab sis rau qee tus neeg, cov kev xaiv no yuav tsis ua haujlwm txhua. Yog tias lawv tsis ua haujlwm rau koj, qhia koj tus kws kho mob Rheumatologist. Lawv yuav yuav sau ntawv sib txawv TNF-alpha inhibitor raws li kauj ruam tom ntej, lossis lawv yuav hais tawm ntau yam sib txawv ntawm DMARD zoo rau nws.

Nco ntsoov hloov kho tus kws kho mob Rheumatologist txog koj lub siab thiab koj xav tias koj cov tshuaj ua haujlwm zoo li cas. Ua ke, koj thiab koj tus kws kho mob tuaj yeem nrhiav txoj kev npaj RA kho mob uas yuav ua haujlwm rau koj.

Q:

Kuv cov khoom noj puas tuaj yeem cuam tshuam rau kuv RA?

A:

Yog lawm. Muaj ntau yam khoom noj uas tuaj yeem pab txo qhov mob hauv koj lub cev. Yog tias koj xav sim hloov kev noj zaub mov kom txhim kho koj cov tsos mob RA, pib los ntawm kev noj zaub mov ntau dua uas muaj omega-3 fatty acids, antioxidant, thiab fiber, xws li txiv ntoo, ntses, txiv ntseej, zaub, thiab ntsuab tshuaj yej. Ib txoj hauv kev zoo los nqa cov zaub mov no rau hauv koj txoj kev ua noj txhua hnub yog ua raws li kev noj haus ntawm Mediterranean. Yog xav paub ntxiv txog kev noj zaub mov noj no thiab lwm yam zaub mov uas yuav pab txo cov tsos mob RA kom yooj yim, mus saib cov kev tiv thaiv kev tiv thaiv rau RA.

Pab Pawg Kho Mob Kev Noj Qab Haus Huv Cov lus teb sawv cev rau kev xav ntawm peb cov kws paub khomob. Txhua cov ntsiab lus yog cov ntaub ntawv nruj me ntsis thiab yuav tsum tsis txhob txiav txim siab cov lus ntuas kho mob.