DAO yog dab tsi? Pob zeb diamond Oxidase Pab Qhia Piav Qhia

Zoo Siab

• DAO yog dab tsi?
• DAO Kev Tsis Txaus Siab thiab Kev Tsim Yeeb Tshuaj Keeb Kwm
• Muaj txiaj ntsig zoo ntawm DAO Cov Khoom Noj Ntxiv
• Digestive Cov tsos mob
• Kev Tiv Thaiv Mob Qhuas Qhuas thiab Mob taub Hau
• Daim tawv nqaij sawv pob
• Tsis Kho
• Muab Kev Noj Qab Nyob Zoo rau DAO Daj Tsis Txaus
• Txhim kho DAO Muaj nuj nqi
• Cov Khoom Noj Kom Tsis Zam Txim
• Kev Nyab Xeeb Txog Kev Nyab Xeeb thiab Ua Xyuas Cov Lus Qhia
• Rau hauv qab Kab

Diamine oxidase (DAO) yog ib qho enzyme thiab kev noj haus zoo uas nquag siv los kho cov tsos mob ntawm histamine tsis raug.

Kev txhawb nqa ntxiv nrog DAO tej zaum yuav muaj qee qhov txiaj ntsig, tab sis kev tshawb fawb muaj tsawg.

Tsab xov xwm no xyuas DAO cov tshuaj pabcuam, nrog rau lawv cov txiaj ntsig, kev siv, thiab kev nyab xeeb.

DAO yog dab tsi?

Diamine oxidase (DAO) yog cov enzyme zom ua hauv koj ob lub raum, thymus, thiab txoj hnyuv hauv koj cov plab zom mov.

Nws lub luag haujlwm tseem ceeb yog zom cov tshuaj histamine ntau nyob hauv koj lub cev (1).

Histamine yog ib txwm muaj tshwm sim los ua ke uas pab tswj cov haujlwm tshwj xeeb ntawm koj lub plab zom mov, tshee, thiab lub cev tsis muaj zog.

Yog tias koj tsis tau muaj qhov tsis haum tshuaj dua, koj yuav tau paub txog cov tsos mob tshwm sim nrog rau theem ntawm cov tshuaj histamine ntau, xws li txhaws ntswg, tawv nqaij ua pob khaus, mob taub hau, thiab txham.

Koj tuaj yeem noj cov tshuaj histamine dhau los ntawm koj cov khoom noj. Nws ib txwm muaj tshwm sim hauv qee yam zaub mov - tshwj xeeb tshaj yog cov uas muaj hnub nyoog, kho, lossis fermented zoo li cheese, cawv, kua qaub, thiab nqaij uas tau haus (1).

DAO khaws cov tshuaj histamine ntau ntau hauv kev noj qab haus huv kom tsis txhob ua rau cov tsos mob tsis txaus ntseeg.

Diamine oxidase (DAO) yog ib qho enzyme uas pab rhuav tshem cov histamine ntau hauv koj lub cev, yog li tshem tawm cov tsos mob tsis xis nyob, xws li txhaws ntswg, khaus tawv, mob taub hau, thiab txham.

DAO Kev Tsis Txaus Siab thiab Kev Tsim Yeeb Tshuaj Keeb Kwm

Histamine intolerance yog ib qho kev mob uas tshwm sim vim tias ua rau kom nce siab txog qib histamine.

Ib qho tsis ntseeg tias yog vim li cas tshuaj histamine tsis kam ua yog DAO deficiency ().

Thaum koj cov DAO theem qis dhau lawm, nws nyuaj rau koj lub cev ua kom cov tshuaj lom neeg lub cev tsis muaj zog thiab ua rau muaj cov histamine ntau dhau. Raws li qhov tshwm sim, cov histamine theem nce ntxiv, uas ua rau ntau cov tsos mob ntawm lub cev.

Cov tsos mob ntawm kev tsis haum tshuaj histamine feem ntau zoo li cov ntawm kev tsis haum tshuaj. Lawv tuaj yeem muaj los ntawm mob me rau mob hnyav thiab suav nrog ():

• ntswg ntswg
• mob taub hau
• khaus tawv, ua pob thiab khaus
• txham
• hawb pob thiab ua pa nyuaj
• lub plawv dhia tsis xwm yeem (arrhythmia)
• raws plab, mob plab, thiab lub plab zom mov
• xeev siab thiab ntuav
• ntshav siab (hypotension)

Ntau yam ua rau ua rau DAO kev ua haujlwm tsawg dua lossis kev tsim cov tshuaj histamine, suav nrog kev hloov caj ces, kev haus cawv, qee yam tshuaj noj, tshuaj tua kab mob hauv plab hnyuv, thiab noj loj ntawm cov khoom muaj histamine ().

Kev tsis quav tshuaj histamine tuaj yeem nyuaj rau kev kuaj mob, vim nws cov tsos mob tsis meej xwm thiab zoo li cov ntawm lwm yam mob (1,).

Yog li, yog tias koj xav tias koj muaj kev tsis txaus siab txog tshuaj histamine tsis haum, sab laj tus kws saib xyuas kev noj qab haus huv kom paub meej cov hauv kev ua rau koj cov tsos mob ua ntej sim kuaj lossis kho koj tus kheej.

Kev tsis quav tshuaj histamine tuaj yeem tshwm sim los ntawm DAO lub cev tsis txaus thiab ua rau muaj ntau cov tsos mob tsis xis nyob uas feem ntau ua rau muaj kev tsis haum.

Muaj txiaj ntsig zoo ntawm DAO Cov Khoom Noj Ntxiv

DAO tsis muaj peev xwm thiab keeb kwm tsis txaus ntseeg tuaj yeem kho ua ke sib txawv, suav nrog los ntawm kev ntxiv nrog DAO.

Cov kev tshawb fawb thaum ntxov qhia tias DAO cov tshuaj pab tuaj yeem txo qee cov tsos mob ntawm kev tsis haum tshuaj histamine, xws li mob taub hau, tawm pob ntawm daim tawv nqaij, thiab kev nyuaj siab.

Digestive Cov tsos mob

Hauv kev tshawb nrhiav 2 lub lis piam hauv 14 tus neeg uas muaj histamine ua tsis taus pa thiab cov tsos mob uas suav nrog mob plab, tsam plab, lossis zawv plab, 93% ntawm cov neeg koom qhia txog kev daws teebmeem tsawg kawg ntawm ib qhov kev mob plab tom qab noj 4.2 mg ntawm DAO ob zaug ib hnub ().

Kev Tiv Thaiv Mob Qhuas Qhuas thiab Mob taub Hau

Kev tshawb nrhiav 1 lub hlis hauv 100 cov neeg uas tau tshawb pom DAO yav dhau los pom tias cov neeg koom nrog kev ua haujlwm txhua hnub nrog DAO muaj 23% txo qis dua lub sijhawm ntawm kev mob taub hau, piv rau cov placebo pawg ().

Daim tawv nqaij sawv pob

Kev tshawb 30-hnub hauv 20 tus neeg muaj tus mob ntev ntev (ua pob khaus raws daim tawv) thiab DAO tsis pom tias cov neeg tuaj koom uas tau txais cov tshuaj ntxiv ob zaug ib hnub muaj kev nyuaj siab ntau ntxiv hauv cov tsos mob thiab yuav tsum tau siv tshuaj tsawg dua los tiv thaiv tshuaj ().

Txawm hais tias cov kev tshawb fawb no qhia tias ntxiv nrog DAO yuav tshem tawm lossis txhim kho cov tsos mob ntawm qhov tsis muaj peev xwm, tsis muaj kev lees paub tias nws ua tau zoo rau txhua tus neeg.

Thaum kawg, xav tau kev tshawb fawb ntxiv los tsim cov ntsiab lus xaus.

Cov kev tshawb fawb thaum ntxov qhia tias DAO cov tshuaj yuav txhim kho qee cov tsos mob cuam tshuam nrog DAO tsis muaj peev xwm thiab histamine tsis raug, nrog rau kev tawm tsam mob, tawm pob ntawm daim tawv nqaij, thiab teeb meem ntawm lub plab. Tseem, yuav tsum muaj kev tshawb fawb ntxiv.

Tsis Kho

Kev nkag siab zoo ntawm keeb kwm tsis txaus ntseeg thiab DAO tsis muaj peev xwm tseem nyob rau theem ntxov.

Ntau yam tuaj yeem cuam tshuam rau kev tsim cov tshuaj DAO thiab histamine hauv ntau qhov chaw ntawm koj lub cev. Hais txog lub hauv paus cag ntawm cov teeb meem no tsis yog yooj yim li hloov DAO nrog kev ntxiv (1,).

DAO pab ua haujlwm kom zom cov tshuaj histamine uas nkag rau hauv koj lub cev sab nraud, xws li los ntawm cov khoom noj lossis dej haus.

Noj cov tshuaj no yuav tsis cuam tshuam rau theem ntawm cov tshuaj histamine uas tsim nyob sab hauv, vim tias hom histamine no tau tawg los ntawm cov enzyme sib txawv hu ua N-methyltransferase ().

Txawm hais tias DAO pab ntxiv tuaj yeem txo cov tsos mob los ntawm kev txo cov tshuaj histamine sab nraud, kev tshawb fawb qhia tau tias lawv tuaj yeem kho cov tshuaj histamine tsis haum lossis DAO tsis muaj peev xwm.

Yog tias koj raug kuaj mob nrog histamine tsis kam lees lossis koj xav tias koj muaj tus mob no, sab laj tus kws kho mob tsim nyog los tsim kho tus kheej raws li koj cov kev xav tau thiab lub hom phiaj kev noj qab haus huv.

Txog rau hnub no, tsis muaj kev tshawb fawb tshawb fawb qhia tau hais tias DAO cov tshuaj pab tuaj yeem kho DAO deficiency lossis histamine ua tsis tau zoo.

Muab Kev Noj Qab Nyob Zoo rau DAO Daj Tsis Txaus

Kev tsis txaus siab rau keeb kwm thiab DAO yog cov xwm txheej nyuaj uas muaj ntau yam cuam tshuam loj rau cov tsos mob tshwm sim.

Tam sim no, ib qho ntawm txoj hauv kev los kho cov mob no yog los ntawm kev noj haus.

Vim tias qee yam khoom noj uas paub tias muaj qib sib txawv ntawm histamine, kev hloov kev noj haus tshwj xeeb tuaj yeem txhim kho cov tsos mob ntawm kev tsis haum xeeb ntawm histamine los ntawm kev txo qis rau cov khoom noj histamine thiab kev noj cov zaub mov uas tuaj yeem ua rau DAO kev ua haujlwm.

Txhim kho DAO Muaj nuj nqi

Kev noj zaub mov zoo tsim los txhim kho histamine ua siab ntev thiab DAO ua haujlwm nrhiav kom tau txais cov khoom noj muaj txiaj ntsig zoo uas koom nrog kev rhuav tshem cov tshuaj histamine, suav nrog tooj liab thiab vitamins B6 thiab C ().

Qee qhov kev tshawb fawb tseem qhia tau tias kev noj cov zaub mov kom muaj txiaj ntsig zoo thiab lwm yam khoom noj muaj txiaj ntsig - zoo li phosphorus, zinc, magnesium, hlau, thiab vitamin B12 - yuav ua lub luag haujlwm hauv kev txhim kho DAO kev ua si ().

Noj cov zaub mov uas tsis muaj cov histamine tsawg yuav txo cov tshuaj histamine thiab txo nws cov khoom ntau hauv koj lub cev. Cov khoom noj muaj keeb kwm tsawg muaj xws li:

• cov nqaij tshiab thiab ntses
• qe
• feem ntau cov zaub tshiab - tshwj tsis yog zaub ntsuab, txiv lws suav, avocado, thiab txaij
• feem ntau cov txiv hmab txiv ntoo tshiab - tshwj tsis yog citrus thiab qee cov txiv ntoo
• roj zoo li txiv maj phaub thiab roj txiv roj
• nplej, suav nrog mov, quinoa, pob kws, teff, thiab millet

Cov Khoom Noj Kom Tsis Zam Txim

Txo lossis tshem tawm cov zaub mov muaj ntau nyob rau hauv histamine lossis cov uas ua rau cov neeg histamine tsim tawm yog lwm txoj hauv kev rau kev tswj cov tsos mob ntawm histamine tsis raug thiab tsawg DAO ntau lawm.

Qee cov khoom noj uas muaj cov tshuaj histamine ntau heev thiab yuav ua rau cov neeg tso cov histamine tso tawm xws li ():

• dej cawv, xws li npias, cawv, thiab cawv
• cov khoom noj muab haus, xws li sauerkraut, pickles, yogurt, thiab kimchi
• ntsuas ntses
• chaw yuj nyuj
• Cov khoom noj uas muaj hnub nyoog, xws li cov chees thiab haus thiab nqaij me me
• nplej
• ceev, xws li txiv laum huab xeeb thiab txiv ntoo
• qee cov txiv hmab txiv ntoo, suav nrog cov txiv hmab txiv ntoo hauv cov txiv ntoo, txiv tsawb, txiv ntaub ntoo, thiab txiv pos nphuab
• qee cov zaub, suav nrog txiv lws suav, spinach, lws suav, thiab avocado
• qee yam khoom noj ntxiv, xim, thiab khaws cia

Vim tias cov zaub mov xaiv noj rau cov khoom noj muaj keeb kwm tsawg tsawg yuav ua rau muaj kev txwv tsawg, koj tuaj yeem muaj kev pheej hmoo ntawm zaub mov tsis zoo thiab txo lub neej zoo (1,).

Yog li, kev noj zaub mov kom tsis tshua muaj histamine tsawg yuav tsum siv ib ntus xwb txhawm rau tshuaj xyuas qhov tsis zoo rau cov zaub mov tshwj xeeb.

Qee tus neeg uas siv tshuaj histamine tsis tuaj yeem tiv taus me me ntawm cov khoom noj muaj protein ntau.

Kev noj zaubmov tshem tawm tuaj yeem pab txheeb xyuas yam khoom noj twg ua rau muaj kev mob tshwm sim ntau tshaj plaws thiab yuav tsum zam kom tsis txhob pub dhau sijhawm thiab cov uas koj tuaj yeem muaj kev noj zaub mov kom tsawg.

Qhov tsim nyog, txoj kev no tau ua tiav nyob rau hauv kev qhia ntawm tus kws kho mob tsim nyog los tiv thaiv teeb meem.

Kev noj zaub mov zoo los pab txhawb DAO ua haujlwm thiab txo cov tshuaj histamine muaj xws li kev tshem tawm cov khoom noj muaj txiaj ntsig thiab kev noj zaub mov kom tsawg ntawm cov khoom noj tshwj xeeb kom paub ntxiv txhim kho DAO muaj nuj nqi.

Kev Nyab Xeeb Txog Kev Nyab Xeeb thiab Ua Xyuas Cov Lus Qhia

Tsis muaj qhov tshwm sim zoo rau kev noj qab haus huv tau tshaj tawm hauv kev tshawb fawb txog DAO pab ntxiv.

Txawm li cas los xij, kev tshawb fawb tseem tsis tshua muaj, yog li kev pom zoo txaus txog kev noj tshuaj rau qhov tshuaj ntxiv no tseem tsis tau tsim.

Feem ntau cov kev tshawb fawb muaj siv koob tshuaj 4.2 mg ntawm DAO ntawm ib lub sijhawm txog 2-3 zaug txhua hnub ua ntej noj mov (,,).

Yog li, qhov tshuaj zoo sib xws yuav zoo rau cov neeg feem ntau - tab sis qhov ntawd tsis txhais tau tias nws tsis muaj kev pheej hmoo 100%.

Qee lub tebchaws zoo li Tebchaws Meskas tsis tswj hwm kev noj zaub mov zoo. Yog li, nws yog lub tswv yim zoo kom ntseeg tau tias koj cov khoom raug xaiv tau raug kuaj rau kev coj dawb huv thiab zoo los ntawm lwm tus neeg sab nrauv, xws li Tebchaws Asmeskas Tshuaj (Pharmacopeia Convention) (USP).

Nco ntsoov tham nrog koj tus kws saib xyuas kev noj qab haus huv ua ntej qhia ib qho ntxiv tshiab rau hauv koj cov zaub mov noj.

Cov koob tshuaj ntawm 4.2 mg ntawm DAO 2-3 lub sijhawm txhua hnub ua ntej noj mov tau tshawb fawb nrog tsis muaj kev qhia txog kev phiv tshuaj. Txawm li cas los xij, kev pom zoo meej rau DAO qhov koob tshuaj tsis tau tsim.

Rau hauv qab Kab

Cov tshuaj DAO tsis tuaj yeem kho cov tshuaj histamine ua tsis tau lossis DAO tsis muaj peev xwm tab sis tuaj yeem txo cov tsos mob los ntawm kev rhuav tshem cov keeb kwm sab nraud ntawm histamine zoo li cov uas los ntawm cov khoom noj thiab dej haus.

Cov kev tshawb fawb ntxiv xav tau los tsim lawv qhov kev ua tau zoo, kev nyab xeeb, thiab ntau npaum li cas, txawm hais tias cov kev tshawb fawb tam sim no tsis muaj kev cuam tshuam loj.

Nco ntsoov sab laj nrog cov kws kho mob paub ua ntej ntxiv cov tshuaj tshiab lossis cov tshuaj noj rau koj cov kev noj qab haus huv.