Tus Sau: John Stephens
Hnub Kev Tsim: 25 Lub Ib Hli Ntuj 2021
Hloov Hnub: 6 Lub Kaum Ib Hli Ntuj 2024
Anonim
Mang Vang - pom koj lub neej zoo ( Official Audio )
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Zoo Siab

Tus mob migraine yog ib qho mob neurological uas cuam tshuam ze li 40 lab tus tib neeg hauv Asmeskas.

Mob taub hau ntau zaus tshwm sim rau ntawm ib sab ntawm lub taub hau. Tej zaum lawv yuav dhau los lossis muaj cov suab nkauj lossis lub ntsej muag txawv uas paub zoo li aura.

Lwm cov tsos mob, xws li xeev ntuav, ntuav, thiab lub teeb rhiab, tuaj yeem tshwm sim thaum lub sij hawm mob taub hau.

Thaum tsis paub meej tias mob migraine tsis paub meej, nws ntseeg tau tias ob qho tib si ib puag ncig thiab caj ces ua si lub luag haujlwm. Hauv qab no, peb yuav los saib ze dua txog kev sib txuas ntawm kev mob taub hau thiab noob caj noob ces.

Mob taub hau tuaj yeem yog caj?

Koj cov DNA, uas muaj koj cov noob, yog ntim rau hauv 23 khub ntawm chromosomes. Koj qub txeeg qub teg ib txheej dhau ntawm koj niam thiab lwm qhov los ntawm koj txiv.


Lub gene yog ib feem ntawm DNA uas muab cov ntaub ntawv qhia yuav ua li cas ua cov protein ntau hauv koj lub cev.

Qee zaum cov noob caj noob ceg tuaj yeem hloov pauv tau, thiab cov kev hloov pauv no yuav ua rau lossis tiv thaiv ib tus neeg rau qee yam mob. Cov kev pauv no muaj peev xwm kis tau los ntawm niam txiv mus rau menyuam.

Hloov pauv lossis caj ces muaj feem tau txuam nrog migraine. Qhov tseeb, tau kwv yees tias ntau dua ib nrab ntawm cov neeg uas muaj mob migraine tsawg kawg yog ib leeg ntawm tsev neeg uas muaj tus mob no.

Tshawb fawb zoo li cas?

Cia mus ntxaum kom tob rau hauv dab tsi cov kws tshawb nrhiav tau kawm txog kev mob caj ces thiab mob taub hau.

Cov noob hloov txuas txuam nrog migraine

Koj yuav tau hnov ​​txog qee qhov kev tshawb fawb hauv xov xwm hais txog cov kev sib txawv ntawm cov noob hloov txuas nrog kev mob taub hau. Qee cov qauv suav nrog:

  • KCNK18. Lub noob no cim tau cov protein hu ua TRESK, uas cuam tshuam nrog cov kev mob thiab muaj nyob hauv thaj chaw mob ntsig txog migraine. Ib qho hloov hauv KCNK18 tau cuam tshuam nrog migraine nrog aura.
  • CKIdelta. Cov gene no nthuav tawm ib qho enzyme uas muaj ntau lub zog hauv lub cev, ib qho yog cuam tshuam nrog koj kev rov mus pw. Raws li kev tshawb nrhiav xyoo 2013, kev hloov pauv tshwj xeeb hauv CKIdelta tau cuam tshuam nrog kev mob taub hau.

Noob variations txuam nrog migraine

Nws yog ib qho tseem ceeb kom taw tes tias feem ntau ntawm kev mob taub hau ntseeg tau tias yog polygenic. Qhov no txhais tau hais tias ntau cov noob caj noob ces ua rau mob. Qhov no tshwm sim vim yog kev hloov caj ces me hu ua ib leeg-nucleotide polymorphisms (SNPs).


Kev tshawb fawb caj ces tau txheeb xyuas ntau dua 40 qhov chaw nyob nrog kev hloov pauv uas cuam tshuam nrog cov hom mob qog ib ce. Cov chaw no feem ntau cuam tshuam nrog rau tej yam xws li ntawm cev thiab cov hlab ntsha qhia txog lossis vascular (hlab ntsha) kev ua haujlwm.

Ib leeg, cov kev txawv txav no yuav muaj cov qauv tsawg. Txawm li cas los xij, thaum ntau ntawm lawv ntau ntau, nws tuaj yeem pab txhawb kev txhim kho kev mob taub hau.

Kev tshawb fawb xyoo 2018 ntawm 1,589 tsev neeg nrog migraine pom ib qho kev nce ntxiv "load" ntawm cov kev hloov hauv noob caj noob ceg piv rau cov pej xeem.

Ntau yam keeb caj ces kuj tshwm sim los txiav txim siab kev tshwj xeeb ntawm migraine. Muaj tsev neeg muaj keeb kwm mob taub hau heev yuav ua rau kom koj muaj:

  • mob taub hau nrog aura
  • muaj kev mob taub hau ntau zuj zus tuaj
  • lub hnub nyoog ua ntej ntawm migraine pib
  • ntau hnub thaum koj yuav tsum siv tshuaj migraine

Puas yog qee hom kev mob taub hau muaj cov caj ces sib zog dua li lwm tus?

Qee hom migraine muaj koom nrog kev paub txog caj ces. Ib qho piv txwv ntawm qhov no yog tsev neeg mob hemiplegic migraine (FHM). Vim tias cov koom haum uas paub, FHM tau kawm ntau yam hauv kev piv rau cov noob caj noob ces ntawm migraine.


FHM yog ib hom mob migraine nrog aura uas ib txwm muaj ua ntej lub hnub nyoog pib dua li lwm hom migraine. Nrog rau lwm cov tsos mob aura tshwm sim, cov neeg uas muaj FHM kuj tseem muaj loog lossis tsis muaj zog ntawm ib sab ntawm lub cev.

Muaj peb lub noob sib txawv uas tau paub los txuam nrog FHM. Lawv yog:

  • CACNA1A
  • ATP1A2
  • SCN1A

Ib qho hloov pauv hauv ib ntawm cov noob caj noob ces tuaj yeem cuam tshuam txog cov xovtooj ntawm lub paj hlwb, uas tuaj yeem tsim kev mob taub hau.

FHM yog pub los ntawm ib tug neeg dhau ntawm nws tus kheej kev ncaj ncees. Qhov no txhais tau tias koj tsuas xav tau ib daim qauv ntawm cov noob sib hloov kom muaj tus mob.

Kev muaj txoj caj ces txuas rau migraine yuav pab tau koj li cas?

Nws yuav zoo li tsis tuaj yeem cuam tshuam, tab sis muaj caj ces txuas rau migraine tuaj yeem yog qhov muaj txiaj ntsig. Qhov ntawd yog vim tias koj tuaj yeem tau txais cov ntaub ntawv tseem ceeb thiab kev txhawb nqa los ntawm koj cov neeg hauv tsev neeg uas nkag siab qhov mob.

Cov ntaub ntawv los ntawm koj tsev neeg cov neeg uas tej zaum yuav pab tau rau koj tus kheej kev paub txog mob taub hau xws li:

  • dab tsi lawv kev mob taub rau taub
  • cov kev mob tshwj xeeb uas lawv tau ntsib dhau los
  • cov kev kho mob lossis tshuaj noj uas pab tswj tau zoo mob taub hau
  • seb lawv tej kev mob taub hau tau hloov pauv ntau zaus, siv mus, lossis lwm yam hauv lawv lub neej
  • lub hnub nyoog uas lawv tau ntsib tus mob taub hau tshiab

Thaum mus ntsib kws kho mob

Yog tias koj muaj cov tsos mob zoo ib yam li kev mob taub hau, teem caij nrog koj tus kws kho mob. Cov tsos mob hauv lub taub hau tuaj yeem suav nrog:

  • mob ib ce lossis caj pas, feem ntau nyob rau ib sab ntawm koj lub taub hau
  • xeev siab thiab ntuav
  • lub teeb rhiab
  • suab rhiab
  • Cov tsos mob aura, uas tuaj yeem yog ua ntej mob taub hau thiab tuaj yeem suav nrog:
    • pom kev pom kev ci ntsa iab ntawm lub teeb
    • hais nyuaj
    • txoj kev xav ua kom tsis muaj zog los yog loog ntawm ib sab ntawm koj lub ntsej muag lossis hauv tes

Qee zaum mob taub hau tuaj yeem yog cov cim ntawm kev mob kub ntxhov. Tau txais kev kho mob sai sai rau mob taub hau uas:

  • los txog tam sim ntawd thiab yog mob hnyav
  • tshwm sim tom qab raug mob rau koj lub taub hau
  • muaj cov tsos mob zoo li txhav txhav, tsis meej pem, lossis loog
  • ntev ntev thiab mob heev dua tom qab siv koj tus kheej

Cov kev kho muaj feem ntau yog dab tsi?

Mob taub hau feem ntau kho nrog tshuaj kho. Muaj ob yam kev siv tshuaj migraine:

  • cov uas yooj yim mob taub mob tuaj
  • cov uas pab tiv thaiv kom txhob mob taub hau los ntawm tshwm sim

Nws kuj muaj qee qhov kev sib txuam uas yuav siv tau. Peb yuav tshawb txhua hom kev kho mob hauv ntau yam hauv qab no.

Cov tshuaj noj rau mob taub hau mob huam tuaj

Koj ib txwm noj cov tshuaj no sai li sai tau thaum koj pib hnov ​​mob zoo li mob hawb pob lossis mob taub hau. Piv txwv li:

  • Tus tshuaj yuav tom tsev muag tshuaj. Cov no suav nrog NSAIDs zoo li ibuprofen (Advil, Motrin), naproxen (Aleve), thiab tshuaj aspirin. Acetaminophen (Tylenol) kuj tseem siv tau.
  • Peb Leeg. Muaj ntau ntau yam ntawm triptans. Cov tshuaj no pab thaiv kev o thiab txwv cov hlab ntshav, txo qhov mob. Qee qhov piv txwv suav nrog sumatriptan (Imitrex), eletriptan (Relax), thiab rizatriptan (Maxalt).
  • Ergot alkaloids. Cov tshuaj no ua haujlwm zoo ib yam li triptans. Lawv yuav raug muab yog tias kho nrog triptans tsis muaj txiaj ntsig. Ib qho piv txwv yog dihydroergotamine (Migranal).
  • Gepants. Nthwv dej tshiab ntawm cov tshuaj migraine thaiv cov peptide uas daws qhov mob.
  • Ditans. Tsev neeg tshiab ntawm cov tshuaj cawm, ditans zoo ib yam li triptans tab sis tuaj yeem siv rau hauv cov neeg uas muaj keeb kwm ntawm lub plawv thiab mob hlab ntsha tawg, vim tias triptans yuav ua rau muaj kev pheej hmoo ntawm teeb meem plawv.

Cov tshuaj uas tiv thaiv kev mob taub hau

Koj tus kws kho mob tuaj yeem sau ntawv rau ib qho ntawm cov tshuaj no yog tias koj muaj kev tawm tsam heev lossis heev kawg kev mob taub hau. Qee cov qauv yog:

  • Anticonvulsants. Cov tshuaj no tau tsim tawm los pab kho qhov qaug dab peg. Piv txwv li suav nrog topiramate (Topamax) thiab txiaj ntsig.
  • Cov tshuaj ntshav siab. Cov no tuaj yeem suav nrog beta-blockers lossis calcium channel blockers.
  • Cov tshuaj tiv thaiv kev ntxhov siab. Amitriptyline, ib qho tshuaj tricyclic antidepressant, yuav siv tau.
  • CGRP inhibitors. Cov no yog hom tshiab uas muab los ntawm kev txhaj tshuaj. Lawv yog cov tshuaj tiv thaiv kab mob uas khi rau qhov chaw txais ntshav hauv lub hlwb uas txhawb nqa vasodilation (nthuav dav cov hlab ntsha).
  • Botox txhaj. Tau txais kev txhaj tshuaj Botox txhua 12 asthiv yuav pab tiv thaiv kev mob taub hau rau qee tus neeg laus.

Kev kho mob sib txuam

Nws kuj muaj ntau yam kev kho mob ua ke uas yuav siv tau rau kev mob taub hau, xws li:

  • Kev qha kuas nyob dleb. Kev ntxhov siab yog ib hom kev mob taub hau heev. Cov kev so kom nyob taus yuav pab koj kom tswj tau koj cov kev ntxhov siab kom nyob qib. Xws li kev ua yoga, kev xav, kev ua pa, thiab ua kom cov leeg mob.
  • Kev Siv Tshuaj Tua Tsiaj. Acupuncture koom nrog tso cov koob txhaj tshuaj rau hauv cov ntsiab lus ntawm daim tawv nqaij. Qhov kev xav no los pab kho qhov kev khiav hluav taws xob hauv lub cev. Nws yuav muaj txiaj ntsig pab txo kev mob taub hau.
  • Tshuaj ntsuab, vitamins, thiab lwm yam minerals. Qee cov tshuaj ntsuab thiab tshuaj ntsuab pab tau nrog cov tsos mob migraine. Qee qhov piv txwv suav nrog butterbur, magnesium, thiab vitamin B-2.

Hauv qab kab

Txawm hais tias cov kws tshawb nrhiav tau txheeb xyuas qhov ua tau rau mob taub hau, tseem muaj ntau yam uas tsis tau paub.

Txawm li cas los xij, los ntawm kev tshawb fawb uas tau ua tiav, nws zoo li muaj kev sib xyaw ua ke ntawm ib puag ncig thiab caj ces ua rau tus mob no.

Kev hloov pauv hauv cov caj ces tshwj xeeb yog txuam nrog qee yam kev mob taub hau, xws li tus neeg mob hemiplegic migraine. Txawm li cas los xij, feem ntau ntawm cov mob migraine feem ntau yuav yog polygenic, lub ntsiab lus hloov hauv ntau caj ces ua rau nws.

Muaj keeb kwm tsev neeg mob taub hau tuaj yeem pab tau rau qhov koj tuaj yeem tau txais cov ntaub ntawv tseem ceeb los ntawm cov neeg hauv tsev neeg uas muaj tus mob tib yam. Koj yuav txawm teb rau cov kev kho mob uas zoo sib xws.

Yog tias koj muaj mob pob txha taub hau uas ua rau nws tuaj yeem nyuaj siab dhau ib hnub, mus ntsib koj tus kws kho mob los tham txog koj cov kev kho mob.

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