Tus Sau: Randy Alexander
Hnub Kev Tsim: 27 Lub Plaub Hlis Ntuj 2021
Hloov Hnub: 15 Lub Kaum Ib Hli Ntuj 2024
Anonim
Pharmacology - ANTICHOLINERGIC & NEUROMUSCULAR BLOCKING AGENTS (MADE EASY)
Daim Duab: Pharmacology - ANTICHOLINERGIC & NEUROMUSCULAR BLOCKING AGENTS (MADE EASY)

Zoo Siab

Txog anticholinergics

Anticholinergics yog cov tshuaj uas thaiv qhov kev txiav txim ntawm. Acetylcholine yog ib tug neurotransmitter, lossis tus neeg xa tshuaj lom neeg. Nws hloov cov cim ntawm qee lub hlwb kom cuam tshuam koj lub cev ua haujlwm li cas.

Anticholinergics tuaj yeem kho ntau yam mob, suav nrog:

  • kev tso zis tsis tu ncua
  • zais zis plooj (OAB)
  • Teeb meem mob ntsws ob leeg tsis txawj zoo (COPD)
  • tej yam lom

Lawv kuj tseem tuaj yeem pab txhawm rau hloov cov leeg tsis tuaj yeem txuam nrog qee yam kab mob xws li Parkinson's kab mob. Qee zaum, lawv tau siv ua ntej kev phais mob los pab tswj lub cev kom ua haujlwm thaum tus neeg kho nrog ua kom tsaug zog.

Nyeem rau:

  • ib daim ntawv teev cov tshuaj anticholinergic
  • ntaub ntawv hais txog lawv ua haujlwm li cas
  • dab tsi koj yuav tsum paub txog lawv cov kev pheej hmoo thiab phiv

Sau cov tshuaj anticholinergics

Anticholinergics tsuas yog muaj nrog cov kws kho mob lub hwj tshuaj. Cov ua piv txwv ntawm cov tshuaj no suav nrog:


  • atropine (Atropen)
  • tswbadonna alkaloids
  • benztropine mesylate (Cogentin)
  • clidinium
  • cyclopentolate (Cyclogyl)
  • darifenacin (Enablex)
  • dicylomine
  • fesoterodine (Toviaz)
  • flavoxate (Urispas)
  • glycopyrrolate
  • homatropine hydrobromide
  • hyoscyamine (Levsinex)
  • ipratropium (Atrovent)
  • orphenadrine
  • oxygenbutynin (Ditropan XL)
  • propantheline (Pro-banthine)
  • scopolamine
  • methscopolamine
  • solifenacin (VESIcare)
  • Tiotropium (Spiriva)
  • tolterodine (Detrol)
  • trihexyphenidyl
  • trospium

Txawm hais tias ua pawg raws li cov tshuaj antihistamine kom noj rau kev ua xua thiab ua chaw pabcuam tsaug zog, diphenhydramine (Benadryl) kuj muaj cov teebmeem anticholinergic.

Txhua yam ntawm cov tshuaj no ua haujlwm los kho cov kev mob tshwj xeeb. Koj tus kws kho mob yuav xaiv cov tshuaj uas zoo tshaj plaws rau koj tus mob.

KOJ PUAS PAUB?

Qee cov tshuaj anticholinergics yog muab los ntawm cov nroj tsuag ntawm lub tsev neeg tuag thaum tsaus ntuj hu ua Solanaceae. Hlawv cov hauv paus hniav, cov cag ntoo, thiab cov noob ntawm cov nroj tsuag no tso cov tshuaj anticholinergics.Inhalation ntawm cov pa luam yeeb tau siv rau ntau pua xyoo los kho kev tiv thaiv ua pa ua pa.


Anticholinergics ua haujlwm li cas

Anticholinergics thaiv cov tshuaj acetylcholine los ntawm qhov khi rau nws cov receptors ntawm qee cov kab mob hlwb. Lawv inhibit kev ua hu ua parasympathetic paj impulses.

Cov leeg kev tsaj lub luag haujlwm yog lub luag haujlwm rau cov leeg tsis tuaj yeem nyob hauv:

  • lub plab zom mov
  • ntsws
  • mob txeeb zig
  • lwm qhov ntawm koj lub cev

Lub paj ua rau lub zog pab tswj cov haujlwm xws li:

  • salivation
  • kev zom plab
  • tso zis
  • tso quav tso zis

Kev thaiv cov kab mob acetylcholine tuaj yeem txo qis:

  • tsis tuaj yeem txav cov leeg
  • kev zom plab
  • tso quav tso zis

Yog li ntawv cov tshuaj no tuaj yeem tsim kev mob tshwm sim, xws li:

  • ceev cov zis
  • muaj lub qhov ncauj qhuav

Kev Siv

Anticholinergics yog siv los kho ntau yam mob. Cov no suav nrog:

  • Mob Hlwb Mob Hlwb Ntev (COPD)
  • overactive zais zis thiab tus kheej
  • lub plab zom zaws, xws li raws plab
  • hawb pob
  • kiv taub hau thiab mob taub hau
  • kev lom los ntawm cov co toxins xws li organophosphates lossis muscarine, uas tuaj yeem pom hauv qee cov tshuaj tua kab thiab cov nceb lom.
  • Cov tsos mob ntawm tus kab mob Parkinson, xws li ua tej leeg txawv txav

Anticholinergics tseem tuaj yeem raug siv ua cov leeg ua kom so ntswg thaum phais mob los pab rau tshuaj loog. Lawv pab:


  • ua kom lub plawv dhia zoo li qub
  • so tus neeg
  • txo cov qaub ncaug kom muaj kua qaub ncaug

Qee tus kws kho mob tau sau ntawv tawm tshuaj anticholinergics rau kev siv daim ntawv lo pab tshem tawm hws ntau dhau. Anticholinergics siv feem ntau rau kev kho mob no yog:

  • glycopyrrolate qab zib
  • oxybutynin qhov ncauj tshuaj

Lus ceebtoom

Raws li tau ua ntau yam tshuaj, anticholinergics tuaj nrog ntau cov lus ceeb toom.

Kev tso cua sov thiab mob stroke tshav kub

Anticholinergics txo qis npaum li cas koj hws, uas tuaj yeem ua rau koj lub cev kub. Thaum tab tom noj ib yam ntawm cov tshuaj no, ceev faj tshwj xeeb kom tsis txhob overheated thaum lub sij hawm:

  • kev tawm dag zog
  • da dej kub
  • huab cua sov

Kev tawm hws tsawg tuaj yeem ua rau koj muaj kev pheej hmoo ntawm mob stroke tshav kub.

Ntau dhau thiab haus dej cawv

Siv ntau dhau ntawm cov tshuaj anticholinergic tuaj yeem ua rau tsis nco qab lossis tuag taus. Cov teebmeem no kuj tseem tuaj yeem yog tias koj noj tshuaj anticholinergics nrog cawv. Cov tsos mob ntawm kev noj ntau dhau muaj xws li:

  • kiv taub hau
  • nkees nkees heev
  • ua npaws
  • mob nyhav
  • tsis meej pem
  • teeb meem ua pa
  • clumsiness thiab hais lus tsis meej
  • lub plawv dhia ceev
  • yaug thiab ua kom sov ntawm daim tawv nqaij

Yog tias koj xav tias koj lossis ib tus neeg koj paub tau noj ntau dhau ntawm cov tshuaj no, hu rau koj tus kws kho mob lossis nrhiav kev qhia los ntawm American Association of Poison Control Center ntawm 1-800-222-1222 lossis hla lawv cov twj online.

Yog tias koj cov tsos mob hnyav, hu 911 lossis mus rau chav kho mob maj nrawm ze tshaj plaws tam sim ntawd.

Cov xwm txheej tsis sib haum xeeb

Anticholinergics tuaj yeem siv los kho ntau yam mob, tab sis nws tsis yog rau txhua tus neeg. Piv txwv li, cov tshuaj no tsis feem ntau siv rau cov neeg laus.

Anticholinergics paub txog ua rau muaj kev kub ntxhov, nco qab, thiab ua kom lub hlwb ua haujlwm hauv cov neeg laus dua 65 xyoos. Qhov tseeb, tsis ntev los no tau txuas siv cov tshuaj tiv thaiv anticholinergics nrog kev pheej hmoo ntawm kev dementia.

Tsis tas li, cov neeg uas muaj cov xwm txheej hauv qab no yuav tsum tsis txhob siv tshuaj anticholinergics:

  • myasthenia gravis
  • hyperthyroidism
  • mob ntsws
  • tsam prostate
  • tawg (ntshav siab)
  • urinary tus mob txhaws
  • lub plawv dhia (tachycardia)
  • lub plawv tsis ua hauj lwm
  • qhov ncauj qhuav
  • hiatal hernia
  • cem quav loj
  • daim siab mob
  • Mob ntsws qis

Qhia koj tus kws kho mob yog tias koj muaj ib qho ntawm cov mob no. Tsis tas li, qhia koj tus kws kho mob yog tias koj muaj keeb kwm ua xua rau anticholinergics.

TSIS TXHOB SIV RAU HAUV COV LAUS

Lub koom haum American Geriatrics Society tau xav kom tsis txhob siv cov tshuaj anticholinergic rau cov laus. Qhov no vim tias cov neeg laus yuav yog cov nyiam cov kev mob tshwm sim ntau dua li cov hluas.

Sab sij huam

Txawm tias thaum siv cov tshuaj no kom tsim nyog, cov kev mob tshwm sim tuaj yeem tshwm sim. Qhov tshwm sim zoo los ntawm cov tshuaj anticholinergics yog nyob ntawm cov tshuaj thiab qhov koj noj.

Cov kev mob tshwm sim tuaj yeem suav nrog:

  • qhov ncauj qhuav
  • qhov muag plooj
  • cem quav
  • tsaug zog
  • Kev ua kom loog
  • lus txhais
  • teeb meem nco
  • teeb meem tso zis
  • tsis meej pem
  • delirium
  • tawm hws tsawg
  • tsis muaj qaub ncaug
DEMENTIA CEEB TOOM

ntawm anticholinergics, nrog rau kev siv cov tshuaj no nyob rau hauv, tau cuam tshuam nrog kev pheej hmoo ntawm dementia. Yog tias koj tau raug noj ib yam ntawm cov tshuaj no thiab muaj kev txhawj xeeb txog qhov kev pheej hmoo no, nco ntsoov nrog koj tus kws kho mob tham.

Tham nrog koj tus kws kho mob

Anticholinergics tuaj yeem siv los kho ntau yam mob. Yog koj xav tias ib cov tshuaj yuav pab tau koj, tham nrog koj tus kws kho mob.

Koj tus kws kho mob tuaj yeem txiav txim siab yog tias kev kho mob nrog tshuaj tiv thaiv mob vichyl tuaj yeem yog qhov kev xaiv zoo rau koj. Lawv kuj tuaj yeem teb cov lus nug uas koj muaj txog:

  • txaus ntshai
  • phiv
  • dab tsi xav kom ua nrog kev kho mob

Hauv qab kab

Anticholinergic tshuaj thaiv qhov kev txiav txim ntawm cov neurotransmitter hu ua acetylcholine. Qhov no inhibits cov leeg leeg lub luag haujlwm rau cov leeg tsis tuaj yeem txav thiab ntau yam ntawm lub cev.

Cov tshuaj no tuaj yeem kho ntau yam kev mob, los ntawm kev ua haujlwm ntau ntxiv rau lub zais zis mus rau lub ntsws muaj mob tsis zoo.

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