Tus Sau: Peter Berry
Hnub Kev Tsim: 12 Lub Xya Hli Ntuj 2021
Hloov Hnub: 12 Lub Kawm Ob Hlis Ntuj 2024
Anonim
Ajovy (fremanezumab-vfrm)
Daim Duab: Ajovy (fremanezumab-vfrm)

Zoo Siab

Ajovy yog dab tsi?

Ajovy yog ib lub npe tshuaj muaj npe tshuaj uas siv los tiv thaiv mob taub hau rau cov neeg laus. Nws los ua tus koob txhaj tshuaj ua ntej. Koj tuaj yeem siv tshuaj txhaj rau Ajovy, lossis tau txais kev txhaj tshuaj Ajovy los ntawm tus kws khomob hauv koj tus kws khomob. Ajovy tuaj yeem raug txhaj tshuaj ib hlis ib zaug lossis ib hlis (ib zaug txhua peb lub hlis).

Ajovy muaj cov tshuaj fremanezumab, uas yog lub cev tshuaj monoclonal. Ib qho tshuaj monoclonal yog ib yam tshuaj uas tsim los ntawm cov tshuaj tiv thaiv kab mob. Nws ua haujlwm los ntawm kev tiv thaiv qee yam ntawm koj lub cev cov protein los ntawm kev ua haujlwm. Ajovy tuaj yeem siv los txhawm rau txhawm rau txhawm rau mob tob tob thiab mob tob hau mob taub hau.

Ib yam tshiab ntawm cov tshuaj

Ajovy yog ib feem ntawm cov chav kawm tshiab ntawm cov tshuaj uas hu ua calcitonin cov noob ntsig txog peptide (CGRP) antagonists. Cov tshuaj no yog thawj cov tshuaj tsim los tiv thaiv mob taub hau.

Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) tau pom zoo Ajovy thaum lub Cuaj Hlis 2018. Ajovy yog qhov tshuaj thib ob hauv CGRP chav thaiv kev tsis zoo uas FDA tau pom zoo los pab tiv thaiv kev mob taub hau.


Nws tseem muaj ob lwm CGRP kev thaiv kev muaj. Cov tshuaj no yog hu ua Emgality (galcanezumab) thiab Aimovig (erenumab). Muaj plaub tus CGRP kev thaiv kev hu ua eptinezumab uas tseem tabtom kawm. Nws yuav tsum pom zoo los ntawm FDA yav tom ntej.

Txij nkawm

Txhawm rau kom paub txog qhov ua tau zoo ntawm Ajovy, saib tshooj "Ajovy siv" hauv qab no.

Ajovy xaj

Ajovy tsuas muaj tsuas yog ua hom tshuaj muaj npe kev lag luam. Tamsis no nws tsis muaj cov ntawv ua tsis raug.

Ajovy muaj cov tshuaj fremanezumab, uas tseem hu ua fremanezumab-vfrm. Qhov laj thawj "-vfrm" tshwm ntawm qhov kawg ntawm lub npe yog los qhia tias cov tshuaj nws txawv ntawm cov tshuaj zoo sib xws uas yuav tsim nyob rau yav tom ntej. Lwm cov tshuaj tiv thaiv monoclonal muaj npe nyob rau qhov sib xws.

Ajovy siv

Tsoom Fwv Tebchaws Asmeskas Khoom Noj thiab Tshuaj (FDA) tau pom zoo rau cov tshuaj xws li Ajovy kho lossis tiv thaiv qee yam mob.

Ajovy rau mob taub hau mob taub hau

FDA tau pom zoo Ajovy txhawm rau pab tiv thaiv kev mob taub hau rau cov neeg laus. Cov mob taub hau no mob hnyav. Lawv tseem yog lub cim tseem ceeb ntawm kev mob taub hau, uas yog kev mob neurological. Hnov mus rau lub teeb thiab suab, xeev siab, ntuav, thiab hais lus nyuaj yog lwm cov tsos mob uas tuaj yeem tshwm sim nrog mob taub hau migraine.


Ajovy tau txais kev pom zoo txhawm rau tiv thaiv ob leeg kev mob taub hau thiab mob taub hau mob taub hau mob ib ce. Lub koom haum International Headache hais tias cov neeg uas mob taub hau mob taub hau tsawg dua 15 mob taub hau lossis mob taub hau txhua lub hlis. Cov neeg uas muaj mob tob hau mob taub hau, ntawm qhov tod tes, hnov ​​15 lossis ntau dua mob taub hau txhua lub hlis nyob li 3 hlis. Thiab tsawg kawg 8 ntawm cov hnub yog hnub migraine.

Ua hauj lwm zoo rau migraine mob taub hau

Ajovy tau pom muaj txiaj ntsig zoo rau kev tiv thaiv kev mob taub hau. Yog xav paub txog kev yuav ua li cas Ajovy ua rau hauv kev tshawb fawb, saib cov tshuaj noj tshuaj cov ntaub ntawv.

American mob taub hau haiv neeg pom zoo siv Ajovy txhawm rau tiv thaiv kev mob taub hau rau cov neeg laus uas tsis muaj peev xwm txo lawv tus naj npawb hnub so txaus nrog rau lwm cov tshuaj. Nws kuj tseem pom zoo kom Ajovy rau cov neeg uas tsis tuaj yeem noj lwm yam tshuaj tiv thaiv kev mob taub hau vim muaj kev phiv lossis tshuaj sib cuam tshuam.

Ajovy phiv

Ajovy tuaj yeem ua rau mob hnyav lossis mob loj. Cov npe hauv qab no muaj qee qhov kev mob tshwm sim thaum yuav noj Ajovy. Daim ntawv teev npe no tsis suav tag nrho cov kev mob tshwm sim.


Yog xav paub ntxiv txog cov kev mob tshwm sim ntawm Ajovy, lossis cov lus qhia txog kev yuav ua li cas nrog cov kev mob tshwm sim uas tsis zoo, tham nrog koj tus kws kho mob lossis kws muag tshuaj.

Ntau cov kev mob tshwm sim

Cov kev mob tshwm sim ntau ntawm Ajovy yog kev txhaj tshuaj ntawm thaj chaw. Qhov no tuaj yeem suav cov kev mob tshwm sim tom qab ntawm qhov chaw uas koj txhaj tshuaj:

  • liab
  • khaus
  • kev mob
  • rhiab

Kev txhaj tshuaj ntawm thaj chaw feem ntau tsis hnyav lossis kav ntev. Ntau cov kev mob tshwm sim no yuav ploj mus li ob peb hnub lossis ob peb lim piam. Tham nrog koj tus kws kho mob lossis kws muag tshuaj yog tias koj cov kev mob tshwm sim loj dua lossis lawv tsis ploj mus.

Cov kev mob tshwm sim hnyav heev

Nws tsis nquag muaj kev phiv tshuaj los ntawm Ajovy, tab sis nws yog qhov ua tau. Cov kev mob tshwm sim loj ntawm Ajovy yog ib qho kev txhaum fab hnyav rau cov tshuaj. Saib hauv qab cov ncauj lus kom ntxaws.

Kev fab tshuaj tiv thaiv

Ib yam li nrog rau cov tshuaj feem ntau, qee cov neeg tuaj yeem muaj kev tsis haum tshuaj tom qab lawv noj Ajovy. Cov tsos mob ntawm kev txhaum fab hnyav tuaj yeem suav nrog:

  • khaus
  • daim tawv nqaij ua pob
  • tso tawm (sov thiab liab nyob hauv koj cov tawv nqaij)

Kev tsis haum tshuaj rau Ajovy yog muaj tsawg. Cov tshwm sim muaj kev txhaum fab hnyav muaj xws li:

  • o ntawm koj tus nplaig, qhov ncauj, lossis caj pas
  • Mob hlwb (o rau hauv koj daim tawv nqaij, feem ntau hauv koj daim tawv muag, daim di ncauj, tes, lossis ko taw)
  • teeb meem ua pa

Yog tias koj muaj qhov tsis haum nrog Ajovy, hu rau koj tus kws kho mob tam sim ntawd. Yog tias koj cov tsos mob zoo li yuav txo tau txoj sia lossis yog koj xav tias koj muaj mob ceev, hu rau 911.

Ntev phiv

Ajovy yog kev pom zoo tsis ntev los no cov tshuaj hauv chav kawm tshiab ntawm cov tshuaj. Raws li qhov tshwm sim, muaj kev tshawb nrhiav lub sijhawm ntev ntev txog Ajovy qhov kev nyab xeeb, thiab paub me ntsis txog nws cov teebmeem ntev mus. Kev tshawb nrhiav ntev tshaj plaws (PS30) ntawm Ajovy kav ntev li ib xyoos, thiab cov neeg nyob hauv txoj kev tshawb no tsis tshaj tawm cov kev mob tshwm sim loj heev.

Qhov chaw txhaj tshuaj tiv thaiv yog qhov tshwm sim feem ntau tshwm sim nyob rau hauv kev tshawb fawb xyoo-xyoo. Cov neeg tshaj tawm cov teebmeem hauv qab no hauv thaj chaw uas tau txhaj tshuaj:

  • kev mob
  • liab
  • los ntshav
  • khaus
  • ua pob lossis sawv tawv

Xaiv rau Ajovy

Muaj lwm yam tshuaj ntxiv uas tuaj yeem pab tiv thaiv mob tob hau. Qee qhov kuj yuav zoo dua rau koj dua lwm tus. Yog tias koj xav nrhiav lwm txoj hauv kev Ajovy, tham nrog koj tus kws kho mob. Lawv tuaj yeem pab koj kawm txog lwm cov tshuaj uas yuav zoo rau koj.

Nov yog qee qhov piv txwv ntawm lwm cov tshuaj uas FDA tau pom zoo los pab tiv thaiv kev mob taub hau:

  • cov beta-blocker propranolol (Inderal, Inderal LA)
  • cov neurotoxin onabotulinumtoxinA (Botox)
  • qee cov tshuaj chua leeg, xws li divalproex sodium (Depakote) lossis topiramate (Topamax, Trokendi XR)
  • lwm cov calcitonin gene-ntsig txog peptide (CGRP) cov thaiv kev tawm tsam: erenumab-aooe (Aimovig) thiab galcanezumab-gnlm (Emgality)

Nov yog qee qhov piv txwv ntawm lwm yam tshuaj uas tuaj yeem siv cov ntawv cim rau kev mob taub hau kev tiv thaiv:

  • qee yam tshuaj chua leeg, xws li tshuaj ntsev kom tsim nyog
  • qee yam tshuaj tiv thaiv kev kub ntxhov, xws li amitriptyline lossis venlafaxine (Effexor XR)
  • qee qhov beta-blockers, xws li metoprolol (Lopressor, Toprol XL) lossis atenolol (Tenormin)

CGRP cov thaiv kev

Ajovy yog ib hom tshuaj tshiab uas hu ua calcitonin gene-ntsig txog peptide (CGRP) antagonist. Xyoo 2018, FDA tau pom zoo Ajovy txhawm rau tiv thaiv mob taub hau, nrog rau ob tug lwm tus neeg lub cev tiv thaiv CGRP: Emgality thiab Aimovig. Plaub qhov tshuaj (eptinezumab) yuav tsum pom zoo sai sai.

Lawv ua haujlwm li cas

Qhov peb CGRP kev thaiv kev uas tam sim no muaj haujlwm ua haujlwm sib txawv me ntsis los pab tiv thaiv kev mob taub hau rau lwm tus.

CGRP yog protein nyob hauv koj lub cev. Nws tau txuas nrog vasodilation (nthuav dav hlab ntsha) thiab mob rau hauv cov hlwb, uas yuav ua rau mob taub hau mob taub hau. Txhawm rau ua rau cov teebmeem no hauv lub hlwb, CGRP xav kom khi (txuas) rau nws cov receptors. Receptors yog cov molecules rau ntawm cov phab ntsa ntawm koj lub hlwb.

Ajovy thiab Emgality ua haujlwm los ntawm kev ua haujlwm rau CGRP. Qhov no txwv tsis pub lub CGRP los txuas rau nws cov neeg txais. Aimovig, ntawm qhov tod tes, ua haujlwm los ntawm kev txuas rau cov receptors lawv tus kheej. Qhov no ua rau CGRP tsis pom zoo rau lawv.

Los ntawm kev tiv thaiv CGRP los ntawm txuas mus rau nws cov receptor, peb yam tshuaj no pab tiv thaiv kom tsis txhob muaj vasodilation thiab o. Vim li ntawd, lawv tuaj yeem pab tiv thaiv mob tob hau.

Sab ua ke

Daim duab qhia piv rau qee cov ntaub ntawv hais txog Aimovig, Ajovy, thiab Emgality. Cov tshuaj no yog peb tus yeeb yam tshuaj tiv thaiv mob CGRP uas tam sim no pom zoo los pab tiv thaiv mob taub hau. (Yog xav paub ntxiv txog yuav ua li cas Ajovy piv nrog cov tshuaj no, saib nqe lus "Ajovy vs. lwm yam tshuaj" hauv qab no.)

AjovyAimovigTxij Nkawm
Pom zoo hnub rau kev mob taub hau kev tiv thaivLub Cuaj Hli 14, 2018Lub 5 Hlis 17, 2018Lub Cuaj Hli 27, 2018
Tshuaj muaj yeesFremanezumab-vfrmErenumab-aooeGalcanezumab-gnlm
Nws yuav siv li casKev txhaj tshuaj rau tus kheej uas yog siv koob txhaj tshuajSiv tshuaj tua tus kheej nrog lwm tus neeg tsav tshebMuab tshuaj tua tus kheej nrog siv tus cwj mem los yog tshuaj txhaj rau qhov mob
Cov tshuaj nojTxhua hli lossis txhua peb lub hlisHliHli
Yuav ua li cas nws ua haujlwmTiv thaiv qhov cuam tshuam ntawm CGRP los ntawm khi rau CGRP, uas txwv tsis pub nws los ntawm khi rau CGRP receptorTiv thaiv qhov cuam tshuam ntawm CGRP los ntawm thaiv cov CGRP receptor, uas tiv thaiv CGRP los ntawm khi rau nwsTiv thaiv qhov cuam tshuam ntawm CGRP los ntawm khi rau CGRP, uas txwv tsis pub nws los ntawm khi rau CGRP receptor
Nqi *$ 575 / hli lossis $ 1,725 ​​/ peb lub hlis twg$ 575 / hli$ 575 / hli

* Cov nqi tuaj yeem sib txawv raws li koj qhov chaw nyob, lub tsev muag tshuaj tau siv, koj cov nyiaj pov hwm kev nyab xeeb, thiab cov phiaj xwm kev pab tsim khoom.

Ajovy vs lwm yam tshuaj

Tej zaum koj yuav xav paub yuav ua li cas Ajovy piv rau lwm cov tshuaj uas tau sau tseg rau kev siv zoo sib xws. Hauv qab no yog cov kev sib piv ntawm Ajovy thiab ntau yam tshuaj noj.

Ajovy vs Aimovig

Ajovy muaj cov tshuaj fremanezumab, uas yog lub cev tshuaj monoclonal. Aimovig muaj erenumab, uas tseem yog lub npe tshuaj monoclonal. Cov tshuaj tiv thaiv monoclonal yog cov tshuaj uas tau tsim los ntawm cov kab mob hauv lub cev. Lawv nres qhov kev ua ntawm qee cov protein nyob hauv koj lub cev.

Ajovy thiab Aimovig ua haujlwm sib txawv me ntsis. Txawm li cas los xij, lawv ob leeg nres qhov kev ua haujlwm ntawm cov protein hu ua calcitonin gene-ntsig txog peptide (CGRP). CGRP ua rau vasodilation (nthuav dav ntawm cov hlab ntsha) thiab mob hauv cov hlwb. Cov teebmeem no yuav ua rau mob tob hau.

Los ntawm kev thaiv CGRP, Ajovy thiab Aimovig pab tiv thaiv kom tsis txhob muaj pa thiab muaj pa. Qhov no tuaj yeem pab tiv thaiv mob tob hau.

Kev Siv

Ajovy thiab Aimovig yog ob leeg tau txais FDA-pom zoo los tiv thaiv kev mob taub hau rau cov neeg laus.

Cov ntawv thiab cov thawj coj

Cov tshuaj Ajovy thiab Aimovig ob qho tib si los ntawm kev txhaj tshuaj uas tau muab nyob hauv qab koj cov tawv nqaij (subcutaneous). Koj tuaj yeem txhaj tshuaj rau koj tus kheej hauv tsev. Ob qho tshuaj no tuaj yeem txhaj tshuaj rau peb tus kheej mus rau hauv peb qho chaw: hauv ntej ntawm koj tus ncej puab, sab nraub qaum koj sab caj npab, lossis plab.

Ajovy los ua ib tus koob txhaj uas tau ntxiv nrog ib koob. Ajovy tuaj yeem muab ua ib koob nrog 225 mg ib hlis ib zaug. Raws li kev hloov pauv, nws tuaj yeem muab ua peb koob ntawm 675 mg uas tau tswj kav peb lub hlis twg (ib hlis ib zaug).

Aimovig yog los ntawm tus kws kho tsheb uas tau pib nrog ib koob tshuaj. Feem ntau nws muab 70-mg txhaj ib hlis ib zaug. Tab sis noj 140-mg ib hlis ib zaug yuav zoo dua rau qee cov neeg.

Phiv thiab txaus ntshai

Ajovy thiab Aimovig ua haujlwm ntawm txoj kev zoo sib xws thiab yog li ntawd ua rau qee qhov kev cuam tshuam zoo tib yam. Lawv kuj ua rau muaj qee qhov kev mob tshwm sim txawv.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim ntau uas tuaj yeem tshwm sim nrog Ajovy, nrog Aimovig, lossis nrog ob qho tshuaj (thaum noj ib leeg).

  • Yuav tshwm sim nrog Ajovy:
    • tsis muaj cov kev mob tshwm sim tshwj xeeb
  • Yuav tshwm sim nrog Aimovig:
    • cem quav
    • mob pob ntseg los yog txha nqaj qaum
    • cov kab mob sab saud xws li mob khaub thuas lossis mob ntswg
    • cov tsos mob khaub thuas zoo li
    • rov qab mob
  • Yuav tshwm sim nrog ob Ajovy thiab Aimovig:
    • Kev txhaj tshuaj ntawm thaj chaw xws li mob, khaus, lossis liab

Cov kev mob tshwm sim hnyav heev

Qhov tshwm sim thawj qhov loj rau ob qho Ajovy thiab Aimovig yog kev fab tshuaj tsis haum. Qhov kev tawm tsam no tsis yog ib txwm muaj, tab sis nws muaj peev xwm ua tau. (Yog xav paub ntxiv, saib "Kev tsis haum tshuaj" nyob rau ntu "Ajovy phiv" saum toj saud).

Kev siv tshuaj tiv thaiv

Hauv kev sim tshuaj rau ob qho tshuaj, feem pua ​​me ntawm cov tib neeg muaj kev tawm tsam tsis haum. Qhov kev tawm tsam no ua rau lawv lub cev tsim cov tshuaj tiv thaiv tawm tsam Ajovy lossis Aimovig.

Cov tshuaj tua kab mob yog cov protein nyob hauv lub cev tiv thaiv kab mob uas tawm tsam cov tshuaj txawv teb chaws hauv koj lub cev. Koj lub cev tuaj yeem tsim cov tshuaj tiv thaiv rau ib qho teeb meem txawv teb chaws twg. Qhov no suav nrog cov tshuaj tiv thaiv monoclonal. Yog tias koj lub cev tsim cov tshuaj tiv thaiv rau Ajovy lossis Aimovig, cov tshuaj yuav tsis ua haujlwm rau koj ntxiv lawm. Tab sis nco ntsoov tias vim Ajovy thiab Aimovig tau pom zoo rau xyoo 2018, nws tseem tseem ntxov dhau los paub txog tias cov nyhuv no yuav zoo li cas thiab nws yuav cuam tshuam li cas rau tib neeg siv cov tshuaj no rau yav tom ntej.

Txij nkawm

Cov tshuaj tsis tau muab piv rau qhov kev sim tshuaj. Txawm li cas los xij, kev tshawb fawb pom ob Ajovy thiab Aimovig ua haujlwm zoo rau kev tiv thaiv ob leeg mob sib txawv thiab mob taub hau mob taub hau ntev.

Ib qho ntxiv, cov lus qhia kho kev mob taub hau pom zoo kom haus ib hom tshuaj uas yog ib txoj kev xaiv rau qee tus neeg. Cov no suav nrog cov neeg uas tsis tuaj yeem txo lawv cov hnub mob taub hau ntau txaus nrog lwm cov tshuaj. Lawv kuj suav nrog cov neeg uas tsis tuaj yeem zam lwm cov tshuaj vim muaj kev phiv los sis cuam tshuam nrog kev siv yeeb tshuaj.

Cov nqi

Tus nqi ntawm Ajovy lossis Aimovig tuaj yeem sib txawv raws li koj txoj kev npaj kho mob. Txhawm rau sib piv cov nqi rau cov tshuaj no, tshawb xyuas GoodRx.com. Tus nqi tiag uas koj yuav them rau cov tshuaj no nyob ntawm koj qhov kev tuav pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj koj tau siv.

Ajovy vs Emgality

Ajovy muaj cov tshuaj fremanezumab, uas yog ib qho kev tiv thaiv monoclonal. Emgality muaj galcanezumab, uas tseem yog lub npe tshuaj monoclonal. Ib qho tshuaj tiv thaiv monoclonal yog ib hom tshuaj tsim los ntawm cov tshuaj tiv thaiv kab mob hauv lub cev. Nws nres qhov kev ua ntawm qee cov protein hauv koj lub cev.

Ajovy thiab Emgality ob leeg nres qhov cov kev ua ntawm calcitonin gene-ntsig txog peptide (CGRP). CGRP yog protein nyob hauv koj lub cev. Nws ua rau vasodilation (nthuav dav ntawm cov hlab ntsha) thiab mob rau cov hlwb, uas yuav ua rau mob taub hau mob taub hau.

Los ntawm kev nres CGRP los ntawm kev ua haujlwm, Ajovy thiab Emgality pab tiv thaiv kom tsis txhob muaj vasodilation thiab mob hauv hlwb. Qhov no tuaj yeem pab tiv thaiv mob tob hau.

Kev Siv

Ajovy thiab Emgality yog ob leeg FDA-tau pom zoo tiv thaiv kev mob taub hau rau cov neeg laus.

Cov ntawv thiab cov thawj coj

Ajovy los ua ib tus koob txhaj uas tau ntxiv nrog ib koob. Emgality los hauv txoj kev tsim ib koob txhaj tshuaj yeeb yaj kiab lossis ib qho xaum.

Tag nrho ob qho ntawm cov tshuaj tau txhaj rau hauv qab koj cov tawv nqaij (subcutaneous). Koj tuaj yeem nqa tus kheej Ajovy thiab Emgality hauv tsev.

Ajovy tuaj yeem siv tus kheej ntawm tus kheej siv ib qhov ntawm ob daim ntawv teem sijhawm sib txawv. Nws tuaj yeem raug muab txhaj ib zaug nrog 225 mg ib hlis ib zaug, lossis ua peb koob sib ntxiv (rau tag nrho ntawm 675 mg) ib zaug txhua peb lub hlis. Koj tus kws kho mob yuav xaiv lub sijhawm zoo rau koj.

Emgality raug muab raws li kev txhaj tshuaj ib zaug ntawm 120 mg, ib hlis ib zaug. (Thawj koob lub hli thawj zaug yog ob koob tshuaj txhaj tag nrho 240 mg.)

Ob leeg Ajovy thiab Emgality tuaj yeem raug txhaj rau hauv peb qhov chaw ua tau: pem hauv ntej ntawm koj tus ncej puab, sab nraub qaum ntawm koj sab caj npab, lossis koj lub plab. Ib qho ntxiv, Emgality tuaj yeem raug txhaj rau hauv koj lub pob tw.

Phiv thiab txaus ntshai

Ajovy thiab Emgality yog cov tshuaj zoo heev thiab ua rau muaj kev cuam tshuam zoo ib yam thiab muaj kev phiv loj heev.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim ntau dua uas tuaj yeem tshwm sim nrog Ajovy, nrog Emgality, lossis nrog ob qho tshuaj (thaum noj ib leeg).

  • Yuav tshwm sim nrog Ajovy:
    • tsis muaj cov kev mob tshwm sim tshwj xeeb
  • Yuav tshwm sim nrog Emgality:
    • rov qab mob
    • ua pa tau kab mob
    • mob caj pas
    • mob sinus tau
  • Yuav tshwm sim nrog ob Ajovy thiab Emgality:
    • Kev txhaj tshuaj ntawm thaj chaw xws li mob, khaus, lossis liab

Cov kev mob tshwm sim hnyav heev

Qhov kev tsis haum tshuaj yog qhov tshwm sim loj rau Ajovy thiab Emgality. Nws tsis nquag muaj qhov tshwm sim zoo li no, tab sis nws muaj peev xwm ua tau. (Yog xav paub ntxiv, saib "Kev tsis haum tshuaj" nyob rau ntu "Ajovy phiv" saum toj saud).

Kev siv tshuaj tiv thaiv

Hauv cov chaw kuaj mob cais rau cov tshuaj Ajovy thiab Emgality, feem pua ​​me me ntawm cov tib neeg muaj kev tiv thaiv kab mob. Qhov kev tiv thaiv kab mob hauv lub cev no ua rau lawv lub cev tsim cov tshuaj tiv thaiv tawm tsam cov tshuaj.

Tshuaj tua kab mob yog cov tshuaj tiv thaiv kab mob hauv lub cev uas tawm tsam cov teeb meem txawv teb chaws hauv koj lub cev. Koj lub cev tuaj yeem tsim cov tshuaj tiv thaiv rau ib yam khoom txawv teb chaws. Qhov no suav nrog cov tshuaj tiv thaiv monoclonal xws li Ajovy thiab Emgality.

Yog tias koj lub cev tsim cov tshuaj tiv thaiv rau Ajovy lossis Emgality, cov tshuaj ntawd yuav tsis ua haujlwm rau koj ntxiv lawm.

Txawm li cas los xij, nws tseem sai dhau los kom paub tias qhov ua tau zoo li cas yuav yog vim tias Ajovy thiab Emgality tau pom zoo rau xyoo 2018. Nws tseem sai dhau los paub txog tias nws yuav cuam tshuam li cas tib neeg siv ob hom tshuaj no rau yav tom ntej.

Txij nkawm

Cov tshuaj tsis tau muab piv rau qhov kev sim tshuaj. Txawm li cas los xij, kev tshawb nrhiav pom ob Ajovy thiab Emgality ua haujlwm zoo rau kev tiv thaiv ob leeg mob sib txawv thiab mob taub hau mob taub hau ntev.

Ib qho ntxiv, ob Ajovy thiab Emgality raug pom zoo los ntawm cov lus qhia kho mob rau cov neeg uas tsis tuaj yeem siv lwm cov tshuaj vim tias muaj kev phiv lossis tshuaj sib cuam tshuam. Lawv kuj tseem pom zoo rau cov neeg uas tsis tuaj yeem txo lawv tus naj npawb ntawm mob taub hau ib hlis ib zaug txaus nrog lwm cov tshuaj.

Cov nqi

Tus nqi rau Ajovy lossis Emgality kuj yuav txawv nyob ntawm koj phiaj xwm kho mob. Txhawm rau sib piv cov nqi rau cov tshuaj no, tshawb xyuas GoodRx.com. Tus nqi tiag uas koj yuav them rau cov tshuaj no nyob ntawm koj qhov kev tuav pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj koj tau siv.

Ajovy vs Botox

Ajovy muaj cov tshuaj fremanezumab, uas yog ib qho kev tiv thaiv monoclonal. Ib qho tshuaj tiv thaiv monoclonal yog ib hom tshuaj tsim los ntawm cov tshuaj tiv thaiv kab mob hauv lub cev. Ajovy pab tiv thaiv kev mob taub hau los ntawm kev txwv tsis pub ua haujlwm ntawm qee yam protein uas ua rau mob migraines.

Lub ntsiab tshuaj tseem ceeb hauv Botox yog onabotulinumtoxinA. Cov tshuaj no yog ib feem ntawm ib chav kawm ntawm cov tshuaj hu ua neurotoxins. Botox ua haujlwm los txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau qhov uas nws tau txhaj. Qhov no ua rau cov leeg ua kom cov phiajcim mob los ntawm qhov hloov. Nws tau xav tias qhov kev ua no pab tiv thaiv kev mob taub hau ua ntej lawv pib.

Kev Siv

FDA tau pom zoo Ajovy txhawm rau tiv thaiv mob tob hau lossis mob tob hau mob taub hau rau cov neeg laus.

Botox tau txais kev pom zoo los tiv thaiv mob tob hau mob taub hau rau cov neeg laus. Botox kuj tseem tau txais kev pom zoo los kho ntau yam mob, suav nrog:

  • leeg txha caj
  • qhov muag tsis pom tseeb
  • tawm hws ntau dhau
  • ncauj tsev menyuam dystonia (mob caj dab sib heev)
  • daim tawv muag daj sib deev

Cov ntawv thiab cov thawj coj

Ajovy ua tau los ua tus muab tshuaj ib zaug xwb. Nws tau muab tshuaj rau hauv qab koj cov tawv nqaij (subcutaneous) uas koj tuaj yeem muab rau koj tus kheej hauv tsev, lossis kom tus kws kho mob muab rau koj ntawm koj tus kws kho mob lub chaw haujlwm.

Ajovy tuaj yeem muab rau ib qho ntawm ob qho kev sib txawv: ib qho 225-mg txhaj ib hlis ib zaug, lossis peb koob sib txawv (tag nrho ntawm 675 mg) ib zaug txhua peb lub hlis. Koj tus kws kho mob yuav xaiv lub sijhawm zoo rau koj.

Ajovy tuaj yeem raug txhaj rau hauv peb qhov chaw tau txais: hauv ntej ntawm koj tus ncej puab, sab nraub qaum koj sab caj npab, lossis lub plab.

Botox kuj tseem raug txhaj tshuaj, tab sis nws ib txwm muab tso hauv kws kho mob lub chaw haujlwm. Nws tau txhaj tshuaj rau hauv cov leeg nqaij (intramuscular), feem ntau txhua 12 asthiv.

Cov chaw uas Botox tau txhaj ib txwm muaj xws li ntawm koj lub hauv pliaj, sab saud thiab ze koj lub pob ntseg, ze rau koj cov plaub hau hauv qab ntawm koj lub caj dab, thiab sab nraum koj lub caj dab thiab xwb pwg. Txhua zaus mus ntsib, koj tus kws kho mob feem ntau yuav muab 31 qhov kev txhaj tshuaj me rau cov chaw no.

Phiv thiab txaus ntshai

Ajovy thiab Botox yog ob qho tib si siv los tiv thaiv kev mob taub hau, tab sis lawv ua haujlwm sib txawv hauv lub cev. Yog li ntawd, lawv muaj qee qhov tshwm sim zoo sib xws, thiab qee qhov sib txawv.

Ntau cov kev mob tshwm sim

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim loj uas tuaj yeem tshwm sim nrog Ajovy, nrog Botox, lossis nrog ob qho tshuaj (thaum noj ib leeg).

  • Yuav tshwm sim nrog Ajovy:
    • ob peb yam cov kev mob tshwm sim
  • Muaj peev xwm tshwm sim nrog Botox:
    • cov tsos mob khaub thuas zoo li
    • mob taub hau lossis zus ua rau mob tob hau mob taub hau
    • tawv muag droop
    • lub ntsej muag cov leeg tuag tes tuag taw
    • caj dab mob
    • leeg khov kho
    • leeg mob thiab tsis muaj zog
  • Yuav tshwm sim nrog ob Ajovy thiab Botox:
    • qhov chaw txhaj tshuaj tiv thaiv

Cov kev mob tshwm sim hnyav heev

Cov npe no muaj cov piv txwv ntawm cov kev mob tshwm sim loj uas tuaj yeem tshwm sim nrog Ajovy, nrog Xultophy, lossis nrog ob qho tshuaj (thaum noj ib leeg).

  • Yuav tshwm sim nrog Ajovy:
    • ob peb yam kev phiv loj heev
  • Muaj peev xwm tshwm sim nrog Botox:
    • kis tuag tes tuag taw rau cov leeg ze ze *
    • muaj teeb meem nqos thiab ua pa
    • loj kis kab mob
  • Yuav tshwm sim nrog ob Ajovy thiab Botox:
    • kev fab tshuaj hnyav heev

* Botox muaj lub thawv ceeb toom los ntawm FDA rau kev kis mob tuag tes tuag taw rau cov leeg ze ze tom qab txhaj tshuaj. Lub thawv ceeb toom yog qhov kev ceeb toom zoo tshaj plaws ntawm FDA tau hais. Nws ceeb toom cov kws kho mob thiab cov neeg mob txog tshuaj phiv uas tuaj yeem tsim kev puas tsuaj.

Txij nkawm

Mob taub hau ntev mob taub hau yog ib qho mob uas ob qho Ajovy thiab Botox siv los tiv thaiv.

Cov txheej txheem kev kho mob pom zoo Ajovy yog ib txoj kev xaiv rau cov neeg uas tuaj yeem tsis tuaj yeem txo lawv tus lej mob taub hau txaus nrog lwm cov tshuaj. Ajovy kuj tseem pom zoo rau cov neeg uas tsis tuaj yeem tiv thaiv lwm yam tshuaj vim tias lawv phiv los sis cuam tshuam nrog tshuaj.

Cov American Academy of Neurology xav pom Botox yog ib txoj kev kho mob rau cov neeg muaj mob tob hau ntev mob taub hau.

Cov kev tshawb fawb soj ntsuam tsis tau ncaj qha piv rau cov txiaj ntsig ntawm Ajovy thiab Botox. Tab sis cais kev tshawb fawb qhia Ajovy thiab Botox ua hauj lwm zoo pab tiv thaiv mob taub hau mob taub hau ntev.

Cov nqi

Tus nqi ntawm Ajovy lossis Botox tuaj yeem sib txawv raws li koj txoj kev npaj khomob. Txhawm rau sib piv cov nqi rau cov tshuaj no, tshawb xyuas GoodRx.com. Tus nqi tiag uas koj yuav them rau cov tshuaj no nyob ntawm koj qhov kev tuav pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj koj tau siv.

Ajovy raug nqi

Ib yam li txhua yam tshuaj, cov nqi rau Ajovy tuaj yeem sib txawv.

Koj tus nqi yuav yog nyob ntawm koj cov nyiaj pov hwm, koj qhov chaw nyob, thiab lub tsev muag tshuaj uas koj tau siv.

Kev pab nyiaj txiag

Yog tias koj xav tau kev txhawb nqa nyiaj txiag los them rau Ajovy, kev pabcuam yeej muaj.

Teva Tshuaj, tus tsim cov khoom lag luam ntawm Ajovy, muaj kev tso nyiaj ua haujlwm uas tuaj yeem pab koj them tsawg dua rau Ajovy. Yog xav paub cov ntaub ntawv ntau ntxiv thiab nrhiav seb koj puas tsim nyog tau txais, mus saib lub vev xaib website.

Ajovy dosv

Cov ntaub ntawv hauv qab no qhia txog kev siv li niaj zaus noj rau Ajovy. Txawm li cas los xij, nco ntsoov siv qhov ntau npaum koj tus kws kho mob sau rau koj. Koj tus kws kho mob yuav txiav txim lub sijhawm noj tshuaj zoo tshaj plaws rau koj.

Cov ntaub ntawv tshuaj thiab qhov ua tau zoo

Ajovy los ua ib koob kom muab cov koob txhaj tshuaj ua ntej. Txhua tus koob txhaj tshuaj muaj 225 mg ntawm fremanezumab hauv 1.5 mL ntawm kev daws.

Ajovy raug muab raws li kev txhaj tshuaj hauv qab koj cov tawv nqaij (subcutaneous). Koj tuaj yeem hno koj tus kheej cov tshuaj hauv tsev, lossis tus kws khomob tuaj yeem muab tshuaj rau koj nyob hauv kws kho mob lub chaw haujlwm.

Koob tshuaj rau migraine tiv thaiv mob taub hau

Muaj ob qho kev pom zoo muab tshuaj rau lub sijhawm:

  • ib qho 225-mg subcutaneous txhaj tshuaj txhua lub hlis, lossis
  • peb 225-mg subcutaneous kev txhaj tshuaj muab ua ke (ib qho dhau ib qho) ib zaug txhua peb lub hlis

Koj thiab koj tus kws kho mob yuav txiav txim lub sijhawm muab tshuaj zoo tshaj rau koj, raws li koj nyiam thiab kev ua neej.

Yog tias kuv plam koob tshuaj?

Yog tias koj tsis nco qab lossis tsis nco qab noj ib qho tshuaj, tswj kev noj tshuaj kom sai li sai raws li koj nco qab.Tom qab ntawv, rov ua dua li ib txwm tau teem tseg.

Piv txwv li, yog tias koj nyob rau ib qho khoom noj txhua lub hlis, npaj koob tshuaj rau plaub lub lim tiam tom qab koj pleev qhov pleev. Yog tias koj nyob rau ntawm ib lub sijhawm plaub hlis, muab cov tshuaj rau 12 lub lis piam tom qab koj cov tshuaj pleev.

Kuv puas yuav tau siv cov tshuaj no ntev?

Yog tias koj thiab koj tus kws kho mob txiav txim siab tias Ajovy muaj kev nyab xeeb thiab ua haujlwm zoo rau koj, koj yuav siv cov tshuaj mus ntev kom tiv thaiv mob taub hau.

Yuav ua li cas noj Ajovy

Ajovy yog kev txhaj tshuaj uas tau muab nyob hauv qab ntawm daim tawv nqaij (subcutaneous) ib hlis ib zaug lossis ib hlis txhua peb lub hlis. Koj tuaj yeem muab cov tshuaj txhaj rau koj tus kheej hauv tsev, lossis kom tus kws kho mob muab cov tshuaj rau koj tom koj tus kws kho mob lub chaw haujlwm. Thawj zaug koj tau txais tshuaj rau Ajovy, koj tus neeg saib xyuas kev noj qab haus huv tuaj yeem piav qhia txog kev txhaj tshuaj rau koj tus kheej li cas.

Ajovy tawm los ua ib qho-koob, 225-mg prefilled syringe. Txhua tus koob txhaj tshuaj tsuas muaj ib zaug tshuaj thiab raug siv kom siv ib zaug thiab ces muab pov tseg.

Hauv qab no yog cov lus qhia txog yuav ua li cas siv cov koob txhaj kom tau npaj. Txog lwm yam ntaub ntawv, vis dis aus, thiab cov duab ntawm cov lus qhia txhaj tshuaj, saib cov kws tsim khoom lub vev xaib.

Yuav txhaj li cas

Koj tus kws kho mob yuav sau tshuaj rau 225 mg ib hlis ib zaug, lossis 675 mg ib hlis ib zaug hauv peb lub hlis (peb hlis twg). Yog tias koj tau raug noj tshuaj 225 mg ib hlis twg, koj yuav muab koj tus kheej txhaj ib zaug. Yog tias koj tau noj tshuaj 675 mg peb hlis twg ib zaug, koj yuav muab koj tus kheej peb koob ntxiv ib koob ntxiv ib zaug.

Npaj mus txhaj

  • Peb caug feeb ua ntej txhaj cov tshuaj, tshem cov koob txhaj tshuaj ntawm lub tub yees. Qhov no tso cai rau cov tshuaj kom sov thiab tuaj rau hauv chav tsev kub. Khaws lub hau rau ntawm daim phwj kom txog thaum koj npaj txhij siv cov koob txhaj tshuaj. (Ajovy tuaj yeem khaws cia rau hauv chav tsev kub txog 24 teev. Yog tias Ajovy muab tso rau sab nraum lub tub yees rau 24 teev yam tsis siv, tsis txhob muab tso rau hauv tub yees. Muab pov tseg hauv koj lub ntim ntim ntse ntse.)
  • Tsis txhob sim kom cov phwj ntub sov kom ceev dua los ntawm kev ua microwaving lossis tso dej kub rau nws. Ib qho ntxiv, tsis txhob co lub taub hau. Ua cov haujlwm no tuaj yeem ua rau Ajovy tsis muaj kev nyab xeeb thiab muaj txiaj ntsig zoo.
  • Thaum koj hle cov phwj tawm ntawm nws lub ntim, nco ntsoov tiv thaiv nws los ntawm lub teeb.
  • Thaum koj tos kom lub koob txhaj tshuaj kom sov txog sov li chav nyob, muab ntaub nplaum lossis paj rwb, cawv cawv, thiab koj lub khob ntim khoom pov tseg. Tsis tas li, nco ntsoov tias koj muaj cov naj npawb tseeb ntawm cov koob txhaj tshuaj rau koj li koob tshuaj.
  • Saib ntawm rab koob tshuaj kom paub tseeb tias cov tshuaj tsis muaj pos huab los yog tas sij hawm. Cov kua yuav tsum tau meej rau me ntsis daj. Nws tsis ua li cas yog tias muaj npuas. Tab sis yog tias cov kua tso tawm los yog muaj huab, lossis yog tias muaj cov khoom me me hauv nws, tsis txhob siv nws. Thiab yog tias muaj cov kab nrib pleb los sis dej xau hauv lub phwj hauv, tsis txhob siv nws. Yog tias xav tau, hu rau koj tus kws kho mob txog kev txais ib qho tshiab.
  • Siv xab npum thiab dej los ntxuav koj ob txhais tes, thiab tom qab ntawd xaiv qhov chaw rau koj txhaj tshuaj. Koj tuaj yeem hno hauv koj daim tawv nqaij rau hauv peb qhov chaw no:
    • sab xub ntiag ntawm koj ob txhais ncej puab (tsawg kawg ob nti saum koj lub hauv caug lossis ob nti hauv qab koj lub puab tais)
    • sab nraub qaum koj sab caj npab
    • koj lub plab (tsawg kawg ob ntiv tawm los ntawm koj lub plab khawm)
  • Yog tias koj xav txhaj cov tshuaj mus rau sab tom qab koj sab npab, qee leej yuav xav tau cov tshuaj rau koj.
  • Siv cov cawv cuaj caum los ntxuav qhov chaw txhaj tshuaj uas koj tau xaiv. Nco ntsoov tias cov cawv tau qhuav ua ntej koj txhaj cov tshuaj.
  • Yog tias koj tau txhaj peb tus kheej rau koj tus kheej, tsis txhob muab koj tus kheej cov kev txhaj tshuaj rau tib qhov chaw. Thiab tsis txhob txhaj rau tej qhov chaw uas nqaij ntuag, liab, caws pliav, tawv nqaij, lossis tawv rau tus kov.

Txhaj Ajovy prefilled cov koob txhaj tshuaj

  1. Hle lub koob txhaj ntawm lub koob txhaj tshuaj thiab muab pov tseg rau hauv thoob khib nyiab.
  2. Maj mam muab txiav tsawg kawg yog ib nti ntawm daim tawv nqaij uas koj xav tso.
  3. Ntxig lub koob txhaj rau hauv daim tawv nqaij pinched ntawm kaum ntawm 45 txog 90 degrees.
  4. Thaum tau muab cov koob tso ua ntej lawm, siv koj tus ntiv tes xoo kom maj mam muab lub taub hau tsaws kom nrawm li mus.
  5. Tom qab txhaj Ajovy, rub rab koob ncaj tawm ntawm daim tawv nqaij thiab tso cov quav. Txhawm rau zam koj tus kheej, tsis txhob rov rab koob.
  6. Maj mam nias lub paj rwb los yog ntaub qhwv rau hauv qhov chaw txhaj tshuaj rau ob peb feeb. Tsis txhob txhuam thaj tsam.
  7. Muab cov koob txhaj tshuaj thiab siv rab koob tso rau hauv koj lub ntim ntim pov tseg tam sim ntawd.

Sijhawm

Ajovy yuav tsum noj ib hlis ib zaug lossis ib hlis txhua peb lub hlis (peb hlis twg), nyob ntawm seb koj tus kws kho mob sau ntawv yuav li cas. Nws tuaj yeem siv tau thaum twg los tau nruab hnub.

Yog tias koj tsis nco qab noj ib zaug, noj Ajovy kom sai li sai tau koj nco qab. Cov koob tshuaj ntxiv yuav tsum yog ib hlis lossis peb hlis tom qab koj noj qhov tshuaj ntawd, nce raws li koj cov kev pom zoo noj tshuaj. Ib qho cuab yeej ceeb toom tshuaj tuaj yeem pab koj nco qab kom coj Ajovy raws sij hawm.

Noj Ajovy nrog zaub mov

Ajovy tuaj yeem noj nrog lossis tsis muaj zaub mov noj.

Ajovy ua haujlwm li cas

Ajovy yog tshuaj tua kab monoclonal. Hom tshuaj no yog cov protein tiv thaiv kab mob tshwj xeeb uas tau tsim hauv chav sim. Ajovy ua haujlwm los ntawm kev txwv cov kev ua haujlwm ntawm cov protein hu ua calcitonin gene-ntsig txog peptide (CGRP). CGRP tau koom nrog hauv vasodilation (nthuav dav ntawm cov hlab ntsha) thiab mob hauv koj lub hlwb.

CGRP ntseeg tau tias yuav ua lub luag haujlwm tseem ceeb ua rau mob taub hau me. Qhov tseeb, thaum tib neeg pib mob taub hau mob taub hau, lawv tau muaj kev ntseeg ntau heev ntawm CGRP nyob rau hauv lawv cov hlab ntshav. Ajovy pab ua kom mob taub hau mob taub hau los ntawm pib los ntawm kev ua kom tsis txhob muaj yam haujlwm ntawm CGRP.

Feem ntau cov tshuaj tsom (ua rau) muaj tshuaj lom neeg ntau yam los sis qhov chaw hauv koj lub cev muaj mob. Tab sis Ajovy thiab lwm yam tshuaj monoclonal tsuas yog tsom ib qho tshuaj hauv lub cev. Raws li qhov tshwm sim, tej zaum yuav muaj tsawg dua kev sib txuam nrog yeeb tshuaj thiab phiv nrog Ajovy. Qhov no yuav ua rau nws yog qhov kev xaiv zoo rau cov neeg uas tsis tuaj yeem siv lwm cov tshuaj vim tias muaj kev phiv lossis tshuaj sib cuam tshuam.

Ajovy kuj tseem yuav yog qhov kev xaiv zoo rau cov neeg uas tau sim sim lwm cov tshuaj, tab sis cov tshuaj tsis ua tsis txaus los txo lawv cov hnub so migraine.

Yuav siv sijhawm ntev npaum li cas ua haujlwm?

Tej zaum nws yuav siv li ob peb lub lis piam rau ib qho kev hloov pauv twg uas Ajovy ua rau pom kev. Thiab nws yuav siv li ob peb lub hlis rau Ajovy kom ua tiav.

Cov txiaj ntsig ntawm kev tshawb fawb pom tau hais tias ntau tus neeg uas tau noj Ajovy tsis tshua pom kev mob taub hau tsawg dua li ib hlis tom qab noj thawj koob. Tau ntau lub hlis, tus naj npawb ntawm migraine hnub txuas ntxiv mus rau cov neeg nyob rau hauv txoj kev tshawb no.

Ajovy thiab cawv

Tsis muaj kev cuam tshuam los ntawm Ajovy thiab cawv.

Txawm li cas los xij, rau qee cov neeg, haus cawv thaum noj cov tshuaj Ajovy yuav zoo li ua rau cov tshuaj tsis muaj zog. Qhov no yog vim cawv yog ib tus mob taub hau rau tib neeg coob, thiab tseem haus cawv ntau yuav ua rau mob taub hau rau lawv.

Yog tias koj pom tias cov cawv ua rau mob tob hau lossis mob taub hau ntau dua, koj yuav tsum zam cov dej haus uas muaj cawv.

Ajovy sib cuam tshuam

Ajovy tsis tau pom tias cuam tshuam nrog lwm yam tshuaj. Txawm li cas los xij, nws tseem tseem ceeb nrog koj tus kws kho mob lossis kws muag tshuaj txog txhua yam tshuaj noj, cov vitamins, tshuaj noj, thiab cov tsis yuav tshuaj uas koj noj ua ntej pib Ajovy.

Ajovy thiab cev xeeb tub

Nws tsis paub yog tias Ajovy muaj kev nyab xeeb siv thaum cev xeeb tub. Thaum Ajovy tau muab rau cov poj niam cev xeeb tub hauv cov tsiaj tshawb fawb, tsis muaj kev pheej hmoo rau kev xeeb tub. Tab sis cov txiaj ntsig ntawm kev tshawb nrhiav tsiaj tsis tau tas li twv seb qhov tshuaj yuav cuam tshuam rau tib neeg li cas.

Yog tias koj xeeb tub los yog xav txog kev xeeb tub, tham nrog koj tus kws kho mob. Lawv tuaj yeem pab txiav txim siab yog tias Ajovy yog qhov kev xaiv zoo rau koj. Koj yuav tsum tau tos siv Ajovy txog thaum koj tsis xeeb tub lawm.

Ajovy thiab pub niam mis

Nws tsis paub meej tias Ajovy hla mus rau tib neeg niam cov kua mis. Yog li, nws tsis paub meej tias Ajovy muaj kev nyab xeeb zoo siv thaum pub niam mis.

Yog tias koj tab tom xav txog kev kho Ajovy thaum koj tseem tab tom pub niam mis, tham nrog koj tus kws kho mob txog cov txiaj ntsig thiab kev pheej hmoo. Yog tias koj pib noj cov tshuaj Ajovy, koj yuav tsum txwv tsis pub mis niam.

Cov lus nug uas nquag muaj txog Ajovy

Nov yog cov lus teb rau qee cov lus nug nquag txog Ajovy.

Yuav Ajovy siv los kho kev mob taub hau mob taub hau tau li cas?

Tsis yog, Ajovy tsis yog kev kho mob rau mob taub hau Ajovy pab tiv thaiv kev mob taub hau ua ntej lawv pib.

Ajovy txawv li cas ntawm lwm cov tshuaj migraine?

Ajovy txawv ntawm ntau lwm cov tshuaj migraine vim tias nws yog ib qho ntawm cov tshuaj thawj tsim los pab tiv thaiv kev mob taub hau. Ajovy yog ib feem ntawm chav kawm tshiab ntawm cov tshuaj hu ua calcitonin gene-ntsig txog peptide (CGRP) antagonists.

Feem ntau lwm yam tshuaj siv los tiv thaiv mob taub hau tau tsim rau ntau lub hom phiaj, xws li kev kho mob qaug dab peg, kev nyuaj siab lossis ntshav siab. Ntau ntawm cov tshuaj no siv tawm-daim ntawv lo txhawm rau pab tiv thaiv mob tob hau.

Ajovy kuj txawv ntawm lwm cov tshuaj migraine ntau yam hauv nws tau txhaj ib hlis ib zaug lossis ib hlis txhua peb lub hlis. Feem ntau lwm yam tshuaj siv los tiv thaiv mob taub hau tuaj ua ntsiav tshuaj uas koj yuav tsum tau noj ib hnub ib zaug.

Lwm txoj kev siv tshuaj yog Botox. Botox kuj tseem yog ib qho kev txhaj tshuaj, tab sis koj tau txais nws ib hlis ib zaug hauv koj tus kws kho mob lub chaw haujlwm. Koj tuaj yeem hno Ajovy rau koj tus kheej hauv tsev lossis kom tus kws kho mob muab kev txhaj tshuaj rau koj tus kws kho mob lub chaw haujlwm.

Tsis tas li, Ajovy yog ib qho tshuaj monoclonal antibody, uas yog hom tshuaj uas tsim los ntawm cov kab mob tiv thaiv kab mob hauv lub cev. Lub siab tsis rhuav tshem cov tshuaj no, zoo ib yam li lwm cov tshuaj feem ntau siv los tiv thaiv mob taub hau. Qhov no txhais tau tias Ajovy thiab lwm cov tshuaj monoclonal muaj tsawg kev sib cuam tshuam yeeb tshuaj dua li lwm cov tshuaj uas pab tiv thaiv kev mob taub hau.

Ajovy puas mob taub hau mob taub hau?

Tsis yog, Ajovy tsis pab kho kev mob taub hau mob taub hau. Tam sim no, tsis muaj tshuaj muaj peev xwm kho kev mob taub hau mob taub hau. Cov tshuaj migraine muaj pab tuaj yeem tiv thaiv lossis kho mob taub hau mob taub hau.

Yog tias kuv noj Ajovy, Kuv puas tuaj yeem tsum tsis noj kuv cov tshuaj tiv thaiv lwm tus?

Qhov ntawd nyob ntawm. Txhua tus neeg teb rau Ajovy sib txawv. Yog tias cov tshuaj txo tus naj npawb ntawm koj lub taub hau mob taub hau kom tsawg rau kev tswj hwm, nws yog tias koj tuaj yeem tso tseg tsis siv lwm cov tshuaj tiv thaiv. Tab sis thaum koj pib noj cov tshuaj Ajovy, koj tus kws kho mob yuav pom zoo muab nws ua ke nrog lwm cov tshuaj tiv thaiv.

Ib qho kev tshawb nrhiav pom tias Ajovy muaj kev nyab xeeb thiab siv tau zoo nrog rau lwm cov tshuaj tiv thaiv kab mob. Lwm yam tshuaj uas koj tus kws kho mob yuav muab nrog Ajovy suav nrog cov tshuaj topiramate (Topamax), propranolol (Inderal), thiab qee yam tshuaj tiv thaiv kev mob nkeeg. Ajovy kuj tseem siv tau nrog onabotulinumtoxinA (Botox).

Tom qab koj sim Ajovy li ob rau peb hlis, koj tus kws kho mob yuav zaum tham nrog koj kom pom seb qhov tshuaj ntawd ua haujlwm zoo li cas rau koj. Thaum lub sijhawm ntawd, neb ob leeg yuav txiav txim siab tias koj yuav tsum tsis noj lwm yam tshuaj tiv thaiv, lossis koj yuav tsum txo koj cov tshuaj rau cov tshuaj no.

Ajovy ov twv

Txhaj tshuaj ntau ntawm Ajovy tuaj yeem ua rau koj muaj feem ntau nrog kev txhaj tshuaj ntawm thaj chaw. Yog tias koj muaj qhov tsis haum lossis hypersensitive rau Ajovy, koj yuav muaj kev pheej hmoo rau kev fab hnyav dua.

Tshuav cov tsos mob

Cov tsos mob ntawm kev noj haus ntau dhau muaj xws li:

  • mob hnyav, khaus, lossis liab ntawm thaj chaw ze ntawm kev txhaj tshuaj
  • yaug
  • khaus
  • angioedema (o hauv qab tawv nqaij)
  • o ntawm tus nplaig, caj pas, lossis qhov ncauj
  • teeb meem ua pa

Dab tsi yog qhov ua txhaum cai dhau

Yog koj xav tias koj tau noj ntau dhau ntawm cov tshuaj no, hu rau koj tus kws kho mob lossis nrhiav kev qhia los ntawm American Association of Poison Control Center ntawm 800-222-1222 lossis hauv lawv cov twj online. Tab sis yog tias koj cov tsos mob hnyav, hu 911 lossis mus rau chav kho mob ze tshaj plaws tam sim ntawd.

Ajovy cov lus ceeb toom

Ua ntej noj Ajovy, nrog koj tus kws kho mob tham txog koj li kev noj qab haus huv keeb kwm. Koj yuav tsum tsis txhob noj Ajovy yog tias koj muaj keeb kwm ntawm kev muaj qhov tsis haum ntshav ntau ntawm Ajovy lossis ib qho twg ntawm cov khoom xyaw. Ib qho kev tsis haum dab tsi tshwm sim tuaj yeem ua rau mob xws li:

  • daim tawv nqaij ua pob
  • khaus
  • teeb meem ua pa
  • angioedema (o hauv qab tawv nqaij)
  • o ntawm tus nplaig, qhov ncauj, thiab qa

Ajovy tas sijhawm

Thaum Ajovy raug tso tawm los ntawm lub tsev muag tshuaj, tus kws muag tshuaj yuav ntxiv hnub tas sijhawm rau cov npe ntawm lub khob. Hnub no ib txwm muaj ib xyoos suav txij hnub pib muab tshuaj rau.

Lub hom phiaj ntawm cov hnub tas sij hawm no yog kom tau txais txiaj ntsig zoo ntawm kev noj tshuaj nyob rau lub sijhawm no. Txoj cai tam sim no ntawm Lub Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) yog kom tsis txhob siv cov tshuaj uas tas sij hawm.

Kev noj tshuaj ntev npaum li cas tuaj yeem nyob ntawm ntau yam, nrog rau seb yuav khaws cia cov tshuaj thiab cia.

Ajovy koob txhaj tshuaj yuav tsum muab cia rau hauv tub yees hauv lub thawv qub los tiv thaiv lawv los ntawm lub teeb. Lawv tuaj yeem muab tso rau hauv lub tub yees kom ruaj khov ntev txog 24 lub hlis, lossis kom txog thaum hnub tas sij hawm uas teev rau hauv lub thawv. Thaum muab tawm hauv lub tub yees, txhua rab koob yuav tsum tau siv li ntawm 24 teev.

Yog tias koj tsis tau siv cov tshuaj uas dhau lub caij nyoog tas sijhawm, tham nrog koj tus kws muag tshuaj txog seb koj puas tseem tuaj yeem siv ntxiv.

Tsis lees paub:Xov Xwm Kho Mob Niaj Hnub No tau ua txhua yam kom paub tseeb tias txhua cov ntaub ntawv yog qhov tseeb, qhov muaj txhij txhua, thiab hloov tshiab cov ntaub ntawv. Txawm li cas los xij, cov kab lus no yuav tsum tsis txhob siv los hloov chaw rau qhov kev paub thiab kev paub ntawm tus neeg muaj ntawv tso cai kho mob. Koj yuav tsum tau sab laj nrog koj tus kws kho mob lossis lwm tus kws saib xyuas kev noj qab haus huv ua ntej noj tshuaj. Cov ntaub ntawv tshuaj muaj nyob ntawm no yuav raug hloov thiab tsis yog npaj rau txhua txoj kev siv, cov lus qhia, kev ceev faj, ceeb toom, kev cuam tshuam nrog tshuaj, kev fab tshuaj, lossis muaj kev cuam tshuam tsis zoo. Qhov tsis muaj lus ceeb toom lossis lwm cov ntaub ntawv rau kev muab tshuaj tsis qhia tias kev sib txuam tshuaj lossis tshuaj muaj kev nyab xeeb, siv tau, lossis tsim nyog rau txhua tus neeg mob lossis txhua qhov siv tshwj xeeb.

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