Mob Myeloid Mob Ntshav Qab Zib (AML)

Zoo Siab

• Cov tsos mob ntawm AML zoo li cas?
• Dab tsi ua rau AML?
• Dab tsi ua rau koj txoj kev pheej hmoo ntawm AML?
• AML muab faib li cas?
• Yuav kuaj li cas thiaj paub AML?
• Cov kev kho mob rau AML yog dab tsi?
• Kev tshem tawm txoj kev kho induction
• Kev pom zoo los kho
• Qhov kev xav kom ntev li cas rau cov neeg uas muaj AML?
• Koj tuaj yeem tiv thaiv AML li cas?

Tus mob hu ua myeloid leukemia (AML) yog dab tsi?

Mob myeloid mob ntshav dawb (AML) yog mob qog noj ntshav uas tshwm sim hauv koj cov ntshav thiab pob txha pob txha.

AML tshwj xeeb cuam tshuam rau cov qe ntshav dawb (WBCs) ntawm koj lub cev, ua rau lawv tsim cov kev tsis xwm yeem. Hauv cov qog nqaij hlav siab, muaj pes tsawg tus qog ua hlav sai sai.

Tus mob no tseem paub los ntawm cov npe hauv qab no:

• mob myelocytic mob leukemia
• mob myelogenous mob ntshav dawb
• mob ntshav nquam ntshav ntau
• mob tsis haum lymphocytic rau mob leukemia

Muaj kwv yees li 19,520 yam mob tshiab ntawm AML nyob rau txhua xyoo hauv Asmeskas, raws li National Cancer Institute (NCI).

Cov tsos mob ntawm AML zoo li cas?

Hauv nws cov theem thaum ntxov, cov tsos mob ntawm AML yuav zoo li mob khaub thuas thiab koj yuav kub taub hau thiab qaug zog.

Lwm cov tsos mob tuaj yeem suav nrog:

• mob pob txha
• nquag los ntswg
• los ntshav thiab o tuaj pos
• doog yooj yim
• tawm hws ntau heev (tshwj xeeb yog thaum tsaus ntuj)
• txog siav
• piav tsis hnyav poob
• hnyav dua qhov qub sijhawm ntawm poj niam

Dab tsi ua rau AML?

AML tshwm sim los ntawm kev txawv txav hauv DNA uas tswj kev tsim cov hlwb hauv koj cov pob txha pob txha.

Yog tias koj muaj AML, koj cov hlwb pob txha tsim muaj ntau yam WBCs uas tsis paub qab hau. Cov hlwb tsis zoo no nws thiaj li dhau los ua mob rau WBCs hu ua myeloblasts.

Cov qog ua haujlwm tsis zoo no tsim tsa thiab hloov cov hlwb noj qab haus huv. Qhov no ua rau koj cov leeg pob txha nres kev ua haujlwm kom zoo, ua rau koj lub cev txhawm rau tiv thaiv kev kis mob.

Nws tsis paub meej meej tias ua li cas rau qhov kev hloov DNA. Qee cov kws kho mob ntseeg tias nws yuav cuam tshuam nrog qee qhov tshuaj lom neeg, tshuaj tua hluav taws xob, thiab txawm tias siv tshuaj kho mob.

Dab tsi ua rau koj txoj kev pheej hmoo ntawm AML?

Koj qhov kev pheej hmoo ntawm kev tsim muaj AML nce nrog lub hnub nyoog. Cov hnub nyoog nruab nrab rau ib tus neeg kuaj mob AML yog muaj txog 68, thiab qhov mob no tsis tshua pom muaj rau menyuam yaus.

AML tseem muaj ntau yam hauv cov txiv neej dua li poj niam, txawm hais tias nws cuam tshuam rau cov tub thiab ntxhais ntawm cov nqi sib npaug.

Kev haus luam yeeb yog xav kom koj txoj kev pheej hmoo ntawm kev tsim muaj AML. Yog tias koj ua haujlwm hauv ib qho kev lag luam uas koj yuav tsum tau nthuav tawm cov tshuaj xws li benzene, koj tseem yuav muaj kev pheej hmoo siab dua.

Koj qhov kev pheej hmoo tseem yuav nce ntxiv yog tias koj muaj kev mob ntshav xws li myelodysplastic syndromes (MDS) lossis kev mob caj ces xws li Down syndrome.

Cov kev pheej hmoo no tsis txhais tau tias koj yuav tsis tsim cov AML. Tib lub sijhawm, nws yuav ua rau koj tsim AML yam tsis tas yuav muaj cov phom sij no.

AML muab faib li cas?

Cov Txheej Txheem Kev Noj Qab Haus Huv Hauv Ntiaj Teb (WHO) muaj cov AML sib txawv:

• AML nrog kev rov qab tshwm sim raws caj ces, xws li kev hloov chromosomal
• AML nrog kev hloov pauv ntawm myelodysplasia
• kev kho mob ntsig txog myeloid neoplasms, uas tuaj yeem tshwm sim los ntawm hluav taws xob lossis tshuaj tua hluav taws xob
• AML, tsis muaj lwm yam teev
• myeloid sarcoma
• myeloid proliferations ntawm Down mob ntsws
• mob leukemia tsis meej xwm ntawm qhov tsis meej xwm los ntawm caj ces

Cov laus ntawm AML kuj tseem muaj nyob hauv cov pawg no. Cov npe ntawm cov subtypes no tuaj yeem qhia cov chromosomal hloov lossis caj ces hloov uas tshwm sim los ntawm AML.

Ib qho piv txwv zoo li no yog AML nrog t (8; 21), qhov twg hloov pauv tshwm sim ntawm chromosomes 8 thiab 21.

Tsis zoo li feem ntau ntawm lwm cov qog nqaij hlav, AML tsis tau muab faib ua hom mob cancer ib txwm muaj.

Yuav kuaj li cas thiaj paub AML?

Koj tus kws kho mob yuav kuaj lub cev thiab kuaj xyuas koj lub siab, cov qog ntshav, thiab nti. Koj tus kws kho mob tseem tuaj yeem xaj cov ntshav mus kuaj xyuas ntshav thiab ntsuas seb koj lub cev muaj WBC li cas.

Thaum kuaj ntshav yuav pab koj tus kws kho mob txiav txim siab seb puas muaj teeb meem, kuaj pob txha pob txha los yog kuaj ib ce los mus kuaj mob rau AML.

Ib qho qauv ntawm cov hlwb pob txha yog noj los ntawm kev ntxig ib rab koob ntev rau hauv koj lub pob txha duav. Qee zaum qog lub caj dab yog qhov chaw me me. Cov qauv yog xa mus rau chav kuaj sim.

Koj tus kws kho mob kuj tseem tuaj yeem hlais pob txha caj qaum, lossis txhaws ua pob qij txha, uas yuav tsum tau thim tawm cov kua hauv koj lub nqaj qaum nrog rab koob me. Cov kua dej txhawm rau kuaj pom muaj cov qe ntshav tsis muaj ntshav.

Cov kev kho mob rau AML yog dab tsi?

Kev kho mob rau AML muaj ob ntu:

Kev tshem tawm txoj kev kho induction

Kev tshem tawm kho induction siv txoj kev kho mob tua cov qog ntshav hauv koj lub cev.

Feem ntau cov neeg nyob hauv tsev kho mob thaum kho vim tias kev siv tshuaj kho mob kuj tseem tua tau cov kab mob hlwb zoo, ua rau koj muaj kev pheej hmoo kis mob thiab los ntshav txawv txav.

Hauv daim ntawv tsis tshua meej txog AML hu ua mob siab promyelocytic leukemia (APL), cov tshuaj anticancer xws li arsenic trioxide lossis tagnrho trans-retinoic acid yuav raug siv los tua cov kev hloov pauv tshwj xeeb hauv cov ntshav qog ntshav. Cov tshuaj no tua cov kab mob qog ntshav thiab ua kom cov ntshav tsis zoo ntawm faib mus.

Kev pom zoo los kho

Kev kho kev pom zoo, uas tseem hu ua kev kho mob tom qab dhau los, yog qhov tseem ceeb heev rau kev ua kom AML tshem tawm thiab tiv thaiv kom rov mob. Lub hom phiaj ntawm kev kho mob zoo tshaj plaws yog los rhuav tshem cov qog ntshav uas tseem tshuav.

Tej zaum koj yuav xav kom hloov qia ntawm tes rau kho cov nyom. Qia hlwb feem ntau siv los pab koj lub cev tsim cov hlwb pob txha tshiab thiab noj qab nyob zoo.

Cov qia hlwb yuav los ntawm tus neeg pub dawb. Yog tias yav dhau los koj tau mob qog ntshav uas tau ploj mus rau hauv kev so, koj tus kws kho mob yuav tshem tawm thiab khaws koj cov qia hlwb tshiab rau kev hloov ntshav yav tom ntej, uas yog hu ua kev hloov kho hlwb qog nqaij hlav.

Txais cov qia hlwb los ntawm tus neeg pub ntshav muaj kev pheej hmoo ntau dua qhov kev hloov ntshav los ntawm koj tus kheej qia hlwb. Hloov ntshav ntawm koj tus kheej qia hlwb, txawm li cas los xij, cuam tshuam txog kev pheej hmoo siab dua rau qee tus neeg vim tias qee cov kab mob qog ntshav tawm tuaj hauv qhov qauv coj los ntawm koj lub cev.

Qhov kev xav kom ntev li cas rau cov neeg uas muaj AML?

Thaum nws los txog rau ntau hom AML, nyob ib ncig ntawm ob feem peb ntawm cov neeg muaj peev xwm ua tiav kev zam txim, raws li American Cancer Society (ACS).

Tus nqi them rov qab nce mus txog yuav luag 90 feem pua ​​rau cov neeg nrog APL. Kev zam txim yuav nyob ntawm ntau yam, xws li tus neeg lub hnub nyoog.

Feem tsib xyoos kom muaj sia nyob rau cov neeg Asmeskas nrog AML yog 27.4 feem pua. Tus nqi tsib xyoo muaj sia nyob rau cov menyuam yaus uas muaj AML yog li ntawm 60 thiab 70 feem pua.

Nrog rau kev txiav txim siab thaum ntxov-sijhawm thiab kev kho mob sai, kev zam txim feem ntau yuav luag txhua tus neeg. Thaum tag nrho cov cim thiab cov tsos mob ntawm AML tau ploj mus, koj yuav suav hais tias nyob hauv kev zam txim. Yog tias koj tau nyob hauv kev zam ntau dua tsib xyoos, koj tau pom tias yuav kho AML.

Yog tias koj pom tias koj muaj cov tsos mob ntawm AML, teem sijhawm nrog koj tus kws kho mob tham txog lawv. Koj yuav tsum tau nrhiav kev kho mob sai sai yog tias koj muaj tsos mob ntawm tus mob los yog kub cev tsis tu ncua.

Koj tuaj yeem tiv thaiv AML li cas?

Yog tias koj ua haujlwm nyob ib puag ncig cov tshuaj phem lossis tshuaj tua hluav taws xob, nco ntsoov hnav ib qho thiab txhua qhov muaj thaiv thaiv kom tsis txhob raug koj.

Nco ntsoov ntsib kws kho mob yog tias koj muaj cov tsos mob uas koj txhawj xeeb txog.