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Hnub Kev Tsim: 20 Lub Cuaj Hli Ntuj 2021
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How Ritonavir acts as booster drug
Daim Duab: How Ritonavir acts as booster drug

Zoo Siab

Noj ritonavir nrog rau lwm cov tshuaj muaj peev xwm ua rau muaj kev phom sij txaus ntshai lossis txo sia. Qhia rau koj tus kws kho mob yog tias koj noj ib qho tshuaj hauv qab no: cov tshuaj ergot xws li dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, hauv Cafergot, hauv Migergot), ergonovine, thiab methylergonovine (Methergine); cov tshuaj rau lub plawv dhia tsis xwm yeem xws li amiodarone (Cordarone, Nexterone, Pacerone), flecainide, propafenone (Rhythmol), thiab quinidine (hauv Nuedexta); thiab sedatives lossis pw tsaug zog tshuaj xws li midazolam (Versed) thiab triazolam (Halcion). Koj tus kws kho mob yuav qhia koj kom tsis txhob noj ritonavir yog tias koj noj ib qho ntawm cov tshuaj no.

Ritonavir yog siv nrog rau lwm cov tshuaj los kho tib neeg cov tshuaj tiv thaiv tus kabmob HIV (HIV). Ritonavir yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua protease inhibitors. Nws ua haujlwm los ntawm kev txo qis hauv cov HIV hauv cov ntshav. Txawm hais tias ritonavir tsis kho HIV, nws yuav txo koj txoj hmoo los ntawm kev tiv thaiv kab mob (AIDS) thiab mob HIV-mob xws li muaj mob hnyav lossis mob cancer. Siv cov tshuaj no nrog rau kev xyaum pw ua ke kom nyab xeeb thiab hloov pauv lwm yam hauv lub neej yuav txo qhov kev pheej hmoo kis tus mob HIV mus rau lwm tus neeg.


Ritonavir los ua tshuaj ntsiav, ntsiav tshuaj, thiab tov (kua) los noj ntawm qhov ncauj. Nws feem ntau yog noj ob zaug ib hnub nrog zaub mov. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj ritonavir raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Koj tus kws kho mob tej zaum yuav pib koj noj tsawg kawg ntawm ritonavir thiab maj mam nce koj cov koob tshuaj, tsis yog ntau tshaj ib zaug txhua 2 rau 3 hnub. Ua raws li cov lus qhia no kom zoo.

Nqos ritonavir ntsiav tshuaj tag nrho. Tsis txhob sib faib, zom, lossis tsoo lawv.

Yog tias koj tab tom noj cov tshuaj ntawm qhov ncauj, siv ib rab koob ntsuas qhov ntsuas, rab koob tshuaj, lossis lub khob los ntsuas qhov tseeb cov kua uas tsim nyog rau txhua koob. Tsis txhob siv cov khoom noj li qub. Koj tuaj yeem siv txoj kev daws teeb meem los ntawm nws tus kheej, lossis koj tuaj yeem txhim kho cov saj los ntawm kev sib xyaw nws nrog 8 ooj mis chocolate lossis xyuas kom meej los yog Advera cov khoom noj muaj txiaj ntsig zoo. Yog tias koj sib tov cov tshuaj nrog ib qho ntawm cov dej no, koj yuav tsum haus cov dej sib tov tsis pub dhau 1 teev tom qab koj sib tov.


Yog tias koj tus kws kho mob qhia koj kom tsis txhob noj ritonavir tsiav tshuaj thiab pib noj cov tshuaj noj, koj yuav muaj kev phiv ntau dua xws li xeev ntuav, ntuav, mob plab, thiab zawv plab sai tom qab koj hloov. Cov tsos mob no yuav zoo tuaj thaum koj lub cev kho rau cov ntsiav tshuaj.

Txuas ntxiv noj ritonavir txawm tias koj xis neej. Tsis txhob tsum tseg ritonavir tsis tas tham nrog koj tus kws kho mob. Yog tias koj tsis nco qab noj ntau dua, noj tsawg tshaj li qhov tau hais tseg, lossis tsum tsis noj tshuaj ritonavir, koj tus mob yuav nyuaj kho.

Cov tshuaj no tuaj yeem siv tshuaj rau lwm yam kev siv. Nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj ritonavir,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau ritonavir, lwm yam tshuaj noj, lossis lwm yam tshuaj hauv ritonavir ntsiav tshuaj, tshuaj ntsiav, lossis tov. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
  • qhia rau koj tus kws kho mob yog tias koj tau noj ib qho ntawm cov tshuaj hauv ntu tseem ceeb lossis ib qho hauv qab no: alfuzosin (Uroxatral), apalutamide (Erleada), cisapride (Propulsid) (tsis muaj nyob hauv Asmeskas), colchicine (Colcrys, Mitigare) hauv cov neeg muaj lub raum lossis daim siab mob, dronedarone (Multaq), lomitapide (Juxtapid), lovastatin (Altoprev), lurasidone (Latuda), pimozide (Orap), ranolazine (Ranexa), sildenafil (tsuas yog Revatio lub npe siv rau kev mob ntsws), simvastatin ( Zocor, hauv Vytorin), St. John lub wort, lossis voriconazole (Vfend). Koj tus kws kho mob yuav qhia koj kom tsis txhob noj ritonavir yog tias koj noj ib lossis ntau dua ntawm cov tshuaj no.
  • thiab qhia koj tus kws kho mob thiab tus kws muag tshuaj tias lwm yam tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj noj vitamins, thiab khoom noj muaj txiaj ntsig koj noj lossis npaj noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: anticoagulants ('ntshav thinners') xws li warfarin (Coumadin, Jantoven) thiab rivaroxaban (Xarelto); cov tshuaj tiv thaiv kab mob xws li amitriptyline, bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban, lwm tus), desipramine (Norpramin), fluoxetine (Prozac), nefazodone, nortriptyline, paroxetine (Paxil), thiab trazodone; atovaquone (Mepron, hauv Malarone); bedaquiline (Sirturo); beta-blockers xws li metoprolol (Lopressor, Toprol XL, hauv Dutoprol, hauv Lopressor HCT) thiab timolol; bosentan (Tracleer); buspirone; calcium channel blockers xws li diltiazem (Cardizem, Cartia, Tiazac, lwm tus), nifedipine (Adalat, Afeditab CR, Procardia), thiab verapamil (Calan, Covera, Verelan, hauv Tarka); cov roj uas txhaws tej tshuaj xws li atorvastatin (Lipitor, hauv Caduet) thiab rosuvastatin (Crestor); clarithromycin (Biaxin, hauv PrevPac); clorazepate (Gen-Xene, Tranxene); colchicine (Colcrys, Mitigare); qee yam tshuaj rau mob qog noj ntshav xws li abemaciclib (Verzenio), dasatinib (Sprycel), encorafenib (Braftovi), ibrutinib (Imbruvica), ivosidenib (Tibsovo), neratinib (Nerlynx), nilotinib (Tasigna), venetoclax (Venclexta), ; dexamethasone; diazepam (Diastat, Valium); digoxin (Lanoxin); dronabinol (Marinol); elagolix (Orilissa); estazolam; fentanyl (Duragesic, Subsys), fostamatinib (Tavalisse), qee yam tshuaj rau kab mob siab C (HCV) xws li boceprevir (tsis muaj nyob hauv Asmeskas; Victrelis), glecaprevir thiab pibrentasvir (Mavyret), thiab simeprevir (tsis muaj nyob hauv Asmeskas; ; Olysio); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); lidocaine (Lidoderm; hauv Xylocaine nrog Epinephrine); lwm cov tshuaj rau tus kab mob HIV xws li atazanavir (Reyataz, hauv Evotaz), darunavir (Prezista, hauv Prezcobix), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), maraviroc (Selzentry), saquinavir (Invirase), Aptivus); tshuaj rau kev ua kom tiav xws li avanafil (Stendra), sildenafil (Viagra), tadalafil (Adcirca, Cialis), thiab vardenafil (Levitra); cov tshuaj noj uas txhawb lub cev tiv thaiv kab mob xws li cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) thiab tacrolimus (Astagraf XL, Prograf); qee cov tshuaj rau qhov chua leeg xws li carbamazepine (Epitol, Equetro, Tegretol, lwm tus), clonazepam (Klonopin), divalproex (Depakote), ethosuximide (Zarontin), lamotrigine (Lamictal), thiab phenytoin (Dilantin, Phenytek); meperidine (Demerol); tshuaj txiav yeeb (Dolophine, Methadose); methamphetamine (Desoxyn); mexiletine; perphenazine; quetiapine (Seroquel); quinine (Qualaquin); rifabutin (Mycobutin); phom phom (Rifadin, Rimactane, hauv Rifamate, hauv Rifater); risperidone; salmeterol (Serevent, hauv Advair); qhov ncauj los yog nqus tshuaj steroids xws li betamethasone, budesonide (Pulmicort), ciclesonide (Alvesco, Omnaris), dexamethasone, fluticasone (Flonase, Flovent, hauv Advair), methylprednisolone (Medrol). mometasone (hauv Dulera). prednisone, thiab triamcinolone; theophylline (Theo 24, Uniphyl, lwm tus); thioridazine; thiab zolpidem (Ambien, Edluar, Intermezzo, lwm tus). Ntau lwm yam tshuaj kuj tseem tuaj yeem cuam tshuam nrog ritonavir, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • yog tias koj noj ritonavir qhov ncauj tawm, kuj qhia rau koj tus kws kho mob yog tias koj noj disulfiram (Antabuse) lossis metronidazole (Flagyl, Nuvessa, Vandazole).
  • qhia rau koj tus kws kho mob yog tias koj tau lossis puas tau muaj lub sijhawm QT ntev (qhov teeb meem tsis tshua muaj lub plawv uas yuav ua rau lub plawv dhia tsis xwm yeem, tsaus muag, lossis cia li tuag kiag), mob ntshav qab zib, hemophilia, ntshav siab lossis triglycerides (rog) hauv cov ntshav, lossis plawv lossis mob rau daim siab, nrog rau tus kab mob siab B lossis C.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj ritonavir, hu rau koj tus kws kho mob tam sim ntawd. Koj yuav tsum tsis txhob noj niam mis yog tias koj kis nrog HIV lossis yog tias koj noj ritonavir.
  • koj yuav tsum paub tias ritonavir tuaj yeem txo qhov kev muaj txiaj ntsig zoo ntawm kev tswj kom tsis txhob muaj menyuam (kev tswj kom tsis muaj menyuam, tshuaj pleev ib ce, lub nplhaib lossis txhaj tshuaj). Tham nrog koj tus kws kho mob txog kev siv lwm txoj kev tswj tsis pub muaj menyuam.
  • koj yuav tsum paub tias koj lub cev rog tuaj yeem nce lossis txav mus rau thaj chaw ntawm koj lub cev, xws li koj sab nraub qaum, caj dab ('' twm hump ''), ob lub mis, thiab ib puag ncig koj lub plab. Koj tuaj yeem pom ib qho ploj ntawm lub cev rog ntawm koj lub ntsej muag, ceg thiab caj npab.
  • koj yuav tsum paub tias koj tuaj yeem ntsib hyperglycemia (nce hauv koj cov piam thaj hauv ntshav) thaum koj tseem noj cov tshuaj no, txawm tias koj tsis tau muaj ntshav qab zib. Qhia rau koj tus kws kho mob tam sim ntawd yog tias koj muaj ib qho ntawm cov tsos mob hauv qab no thaum koj noj ritonavir: nqhis dej heev, tso zis heev, tshaib plab heev, plooj tsis pom kev, lossis tsis muaj zog. Nws yog ib qho tseem ceeb heev uas yuav tau hu rau koj tus kws kho mob sai li sai tau uas koj muaj cov tsos mob no, vim tias cov ntshav qab zib uas tsis tau kho nws tuaj yeem ua rau mob hnyav hu ua ketoacidosis. Ketoacidosis tuaj yeem dhau los ua neeg muaj sia nyob yog tias tsis kho thaum ntxov. Cov tsos mob ntawm ketoacidosis suav nrog qhov ncauj qhuav, xeev siab thiab ntuav, ua pa luv, ua pa uas hnov ​​tsw thiab tsis nco qab.
  • koj yuav tsum paub tias thaum koj tab tom noj tshuaj los kho kab mob HIV, koj lub cev tiv thaiv kab mob yuav muaj zog thiab pib tawm tsam lwm yam kev mob uas twb muaj hauv koj lub cev lawm. Qhov no tuaj yeem ua rau koj tsim cov tsos mob ntawm cov mob ntawd. Yog tias koj muaj cov tsos mob tshiab lossis mob hnyav tom qab pib kho nrog ritonavir, nco ntsoov qhia koj tus kws kho mob.

Tshwj tsis yog koj tus kws kho mob qhia lwm yam, noj koj cov zaub mov ib txwm muaj.


Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Ritonavir yuav ua rau muaj kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • tsaug zog
  • zawv plab
  • roj
  • Kev mob siab
  • hloov lub peev xwm los saj cov khoom noj
  • mob taub hau
  • loog, hlawv, lossis tingling ntawm txhais tes, taw, lossis thaj tsam ncig lub qhov ncauj
  • leeg mob lossis mob pob qij txha
  • mob plab, xeev siab thiab ntuav

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob hauv qab no, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

  • blistering lossis tev ntawm daim tawv nqaij
  • ua pob
  • khaus
  • o ntawm lub qhov muag, ntsej muag, nplaig, daim di ncauj, lossis caj pas
  • nruj ntawm lub caj pas
  • ua pa nyuaj lossis nqos
  • xeev siab
  • ntuav
  • mob plab
  • nkees dhau heev lawm
  • tsis muaj lub zog
  • tsis qab los noj mov
  • mob hauv sab saud hauv plab
  • daj ntawm daim tawv nqaij lossis qhov muag
  • kiv taub hau
  • lub teeb ci ntsa iab
  • tsis nco qab
  • lub plawv dhia tsis xwm yeem

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Ritonavir yuav ua rau muaj kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum koj tseem noj cov tshuaj no.

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws cov ntsiav tshuaj thiab daws hauv chav sov. Tsis txhob muab cov tshuaj tov thiab tsis txhob cia kom kub dhau lossis txias heev. Nws yog qhov zoo tshaj plaws hauv tub yees ritonavir tsiav tshuaj, tab sis koj tuaj yeem khaws cia hauv chav tsev ntev txog 30 hnub.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Nws yog ib qho tseem ceeb kom tau txais kev pab kho mob sai li sai tau yog tias tus menyuam haus ntau tshaj li qhov ib txwm siv ntawm cov tshuaj. Txoj kev hais daws no haus cawv ntau ntau uas yuav tsim kev puas tsuaj rau ib tug menyuam.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

  • loog, hlawv, lossis tingling ntawm txhais tes lossis taw

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee qhov kuaj sim kuaj xyuas koj cov lus teb rau ritonavir.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Norvir®
  • RTV
Kawg Kho - 01/15/2021

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