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PULMOZYME® (dornase alfa) Mechanism of Action for Cystic Fibrosis
Daim Duab: PULMOZYME® (dornase alfa) Mechanism of Action for Cystic Fibrosis

Zoo Siab

Dornase alfa yog siv los txo cov neeg muaj mob ntsws thiab txhim kho kev mob ntsws hauv cov neeg mob cystic fibrosis. Nws rhuav tshem cov tuab ntawm cov hlab cua, ua rau huab cua ntws zoo dua thiab tiv thaiv cov kab mob los ntawm kev tsim tsa.

Cov tshuaj no qee zaum sau tseg rau lwm qhov kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Dornase alfa los ua kev daws teeb meem rau kev nqus pa ntawm qhov ncauj. Nws feem ntau yog noj ib lossis ob zaug hauv ib hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Siv dornase alfa raws nraim li qhia. Tsis txhob siv ntau dua los yog tsawg dua ntawm nws lossis siv ntau dua li uas koj tus kws kho mob pom zoo.

Dornase alfa yog siv los kho cystic fibrosis tab sis nws tsis kho nws. Siv txuas ntxiv siv dornase alfa txawm hais tias koj xis nyob. Tsis txhob tso tseg siv cov dornase alfa yam tsis tau tham nrog koj tus kws kho mob.

Ua ntej koj siv dornase alfa thawj zaug, nyeem cov ntawv sau sau tseg uas tuaj nrog nws. Nug koj tus kws kho mob, kws tshuaj, lossis kws kho pa kom paub siv cov txheej txheem kom yog. Xyaum siv lub tshuaj tua hluav taws thaum nws nyob hauv nws qhov chaw nyob. Tsuas yog siv cov tshuaj tua hluav taws uas tau pom zoo los ntawm koj tus kws kho mob.


Ua ntej siv dornase alfa,

  • qhia rau koj tus kws kho mob thiab kws tshuaj yog tias koj ua xua rau dornase alfa lossis lwm yam tshuaj.
  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj uas siv tshuaj thiab cov ntawv uas tsis yog kws kho mob koj noj, suav nrog cov vitamins.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum siv dornase alfa, hu rau koj tus kws kho mob.

Siv cov tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob siv ob koob tshuaj los ua rau qhov ploj lawm.

Dornase alfa yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus.

  • lub suab hloov
  • mob caj pas
  • txhaws qa
  • qhov muag voos
  • ua pob

Yog tias koj muaj cov tsos mob li nram no, hu rau koj tus kws kho mob tam sim ntawd.

  • nce ua pa nyuaj
  • mob hauv siab

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).


Khaws cov tshuaj no rau hauv lub thauv nws tuaj nrog hauv, kaw kom nruj thiab ncav cuag cov menyuam yaus. Khaws nws hauv lub tub yees thiab tiv thaiv nws los ntawm tshav ntuj. Tsis txhob nthuav tawm cov tshuaj rau qhov sov tshaj 24 teev. Tej ampule uas tau qhib rau ntau dua 24 teev yuav tsum tau muab pov tseg. Muab cov ampules pov tseg yog tias cov tshuaj zoo li huab lossis discolored.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.


Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj yam kuaj sim koj cov lus teb rau dornase alfa.

Tsis txhob dilute los yog sib tov dornase alfa nrog lwm cov tshuaj hauv lub khob haus dej.

Inhalation khoom siv yuav tsum tau tu. Ua raws li cov lus qhia sau ntawm tus neeg tsim khoom los saib xyuas lub tshuab pa.

Tsis txhob cia lwm tus siv koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Pulmozyme®
  • DNase
  • recombinant tib neeg deoxyribonuclease
Kawg Kho - 11/15/2017

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