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Sulphasalazine (DMARD) - Pharmacology, mechanism of action, metabolism, side effects
Daim Duab: Sulphasalazine (DMARD) - Pharmacology, mechanism of action, metabolism, side effects

Zoo Siab

Sulfasalazine siv rau kev kho mob hauv plab hnyuv, mob raws plab (tso zis tawm ntau zaus), tso ntshav tawm ntawm lub qhov txhab, thiab mob plab hauv cov neeg mob ulcerative colitis, qhov mob uas yog txoj hnyuv mob. Sulfasalazine qeeb-tso tawm (Azulfidine EN-tabs) kuj tseem siv los kho kev mob caj dab hauv cov neeg laus thiab cov menyuam yaus uas nws tus mob tsis tau teb zoo rau lwm cov tshuaj. Sulfasalazine nyob hauv chav kawm ntawm cov tshuaj hu ua tshuaj los tiv thaiv. Nws ua haujlwm los ntawm kev txo qhov o (o) hauv lub cev.

Sulfasalazine los ua cov haujlwm tsis tu ncua thiab ncua-tso tawm (tso tawm cov tshuaj hauv txoj hnyuv kom tiv thaiv kev ua haujlwm rau lub plab thiab tso cai rau cov tshuaj ua haujlwm hauv txoj hnyuv uas nws qhov xav tau) cov ntsiav tshuaj. Feem ntau nws yuav noj plaub zaug nyob rau ib hnub hauv kev muab faib kom sib npaug ib hnub dhau li kom tsis pub ntau tshaj 8 teev cais tawm ob zaug twg, yog tias ua tau. Noj sulfasalazine tom qab noj mov lossis nrog lub teeb txom ncauj, tom qab ntawd haus ib khob dej. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj sulfasalazine raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.


Nqos cov ntsiav tshuaj tag nrho; tsis txhob zawm thiab zom lawv.

Haus dej kom ntau (yam tsawg rau mus rau yim khob dej los yog lwm yam dej haus rau ib hnub) thaum noj sulfasalazine.

Txuas ntxiv noj sulfasalazine txawm hais tias koj xis nyob. Tsis txhob tsum tsis txhob noj cov tshuaj sulfasalazine tsis tham nrog koj tus kws kho mob.

Sulfasalazine tseem siv rau kev kho mob hauv plab hnyuv, mob raws plab (nquag tso quav), tawm ntawm lub qhov quav, thiab mob plab hauv Crohn's kab mob. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo uas yuav siv cov tshuaj no rau koj tus mob.

Ua ntej noj sulfasalazine,

  • qhia rau koj tus kws kho mob yog tias koj muaj kev fab tshuaj rau sulfasalazine, sulfapyridine, aspirin, choline magnesium trisalicylate (Triosal, Trilisate), choline salicylate (Arthropan), mesalamine (Asacol, Pentasa, Rowasa), salsalate (Argesic-SA, Disalcid, Salgesic, lwm tus) , tshuaj sulfa, trisalicylate (Tricosal, Trilisate), lossis lwm yam tshuaj.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov ntawv uas tsis yog kws kho mob koj noj, tshwj xeeb yog digoxin (Lanoxin), folic acid, thiab vitamins.
  • qhia rau koj tus kws kho mob yog tias koj tau lossis muaj mob hawb pob, lub raum lossis mob siab, mob hnyuv, mob ntshav, lossis txhaws hauv txoj hnyuv lossis lub plab.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj sulfasalazine, hu rau koj tus kws kho mob.
  • npaj ua kom tsis txhob muaj qhov phom sij lossis tsis haum rau lub hnub ci thiab hnav khaub ncaws tiv thaiv, tsom iav, thiab tshuaj pleev thaiv hnub. Sulfasalazine yuav ua rau koj cov tawv nqaij tiv tshav ntuj.

Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav txog sijhawm rau koj cov tshuaj txuas ntxiv, hla cov koob tshuaj ploj thiab txuas ntxiv koj cov sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.


Sulfasalazine tuaj yeem ua rau phiv. Sulfasalazine ua rau cov me nyuam tsis muaj peev xwm ib ntus. Kev tsuj ntxiv rov qab thaum cov tshuaj raug tso tseg. Nws kuj tseem tuaj yeem ua rau koj cov zis lossis tawv nqaij ua rau daj ntseg txiv kab ntxwv; cov nyhuv no yog tsis muaj mob.

Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • zawv plab
  • mob taub hau
  • tsis qab los noj mov
  • mob plab
  • ntuav
  • mob plab

Yog tias koj muaj ib qho ntawm cov tsos mob hauv qab no, tsum tsis txhob noj sulfasalazine thiab hu rau koj tus kws kho mob tam sim ntawd:

  • daim tawv nqaij ua pob
  • khaus
  • khaus
  • o tuaj
  • mob caj pas
  • ua npaws
  • sib koom ua ke los yog mob leeg ib leeg
  • tawv nqaij daj lossis daj
  • teeb meem nqos
  • nkees nkees
  • ntshav txawv lossis doog ntshav
  • tsis muaj zog

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).


Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob tuaj yeem xaj yam kev kuaj ntshav kuaj xyuas koj cov lus teb rau sulfasalazine.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Azulfidine®
  • Azulfidine® EN-tabs®
Kawg Siv - 05/15/2017

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