Tus Sau: Gregory Harris
Hnub Kev Tsim: 7 Lub Plaub Hlis Ntuj 2021
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Letermovir as CMV Prophylaxis in HSCT Patients
Daim Duab: Letermovir as CMV Prophylaxis in HSCT Patients

Zoo Siab

Letermovir yog siv los pab tiv thaiv cytomegalovirus (CMV) kev kis kab mob thiab kab mob hauv qee cov neeg uas tau txais hematopoietic qia-cell hloov (HSCT; tus txheej txheem uas hloov cov hlwb pob txha muaj mob hlwb pob txha zoo) thiab muaj kev pheej hmoo ntawm kev tsim kab mob CMV Cov. Letermovir yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua antivirals. Nws ua haujlwm los ntawm kev maj mam loj hlob ntawm CMV.

Letermovir los ua ib ntsiav tshuaj los noj ntawm qhov ncauj. Feem ntau nws noj nrog lossis tsis noj ib zaug ib hnub. Koj tus kws kho mob tej zaum yuav qhia koj kom pib noj cov tshuaj letermovir tom qab koj tau hloov ntshav thiab kom tsis txhob noj tshuaj 100 hnub tom qab hloov ntshav. Siv letermovir nyob ib ncig ntawm tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj letermovir raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Nqos cov ntsiav tshuaj tag nrho; tsis txhob sib faib, zom, lossis tsoo lawv.


Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj cov letermovir,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau letermovir, lwm yam tshuaj noj, lossis lwm yam tshuaj hauv cov ntsiav tshuaj letermovir. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
  • qhia rau koj tus kws kho mob yog tias koj noj cov tshuaj ergot alkaloids xws li ergotamine (Ergomar, hauv Cafergot, Migergot), thiab dihydroergotamine (D.H.E. 45, Migranal), thiab pimozide (Orap). Koj tus kws kho mob yuav qhia koj kom tsis txhob noj cov tshuaj no yog tias koj noj cov tshuaj letermovir. Kuj qhia koj tus kws kho mob yog tias koj noj tshuaj cyclosporine nrog rau simvastatin lossis pitavastatin. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj cov tshuaj sib xyaw ntawm cov tshuaj nrog letermovir.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txhua yam ntawm cov hauv qab no: amiodarone (Nexterone, Pacerone); cyclosporine (Gengraf, Neoral, Sandimmune); fentanyl (Actiq, Duragesic, Subsys, lwm tus); glyburide (Diabeta, Glynase); HMG-CoA reductase inhibitors xws li atorvastatin (Lipitor, hauv Caduet), fluvastatin (Lescol), lovastatin (Altoprev), pitavastatin (Livalo, Zypitamag), pravastatin (Pravachol), rosuvastatin (Crestor), thiab simvastatin (Flolipid, Zocor) Vytorin); omeprazole (Prilosec, hauv Yosprala, Zegerid); pantoprazole (Protonix); phenytoin (Dilantin, Phenytek); sirolimus (Rapamune); quinidine (hauv Nuedexta); repaglinide (Prandin); rifampin (Rifadin, Rimactane, hauv Rfater, Rifamate), rosiglitazone (Avandia); tacrolimus (Astagraf, Envarsus, Prograf); voriconazole (Vfend); thiab warfarin (Coumadin, Jantoven). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm yam tshuaj kuj tuaj yeem cuam tshuam nrog letermovir, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob rau hauv daim ntawv no.
  • qhia rau koj tus kws kho mob yog tias koj tau lossis tau muaj mob raum lossis mob siab.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj cov tshuaj letermovir, hu rau koj tus kws kho mob.
  • yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws khomob lossis kws kho hniav tias koj noj cov tshuaj letermovir.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.


Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Letermovir yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • xeev siab
  • ntuav
  • zawv plab
  • mob plab
  • o ntawm koj txhais caj npab lossis ceg
  • mob taub hau
  • nkees heev

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no hu rau koj tus kws kho mob:

  • lub plawv dhia nrawm lossis ceev; zoo li tsis muaj zog lossis kiv taub hau, txog siav siav, mob hauv siab

Letermovir tuaj yeem tsim kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).


Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj yam kuaj sim koj lub cev lus teb rau letermovir.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Prevymis®
Kawg Kho - 02/15/2018

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