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Dupilumab Txhaj Tshuaj - Tshuaj Kho Mob
Dupilumab Txhaj Tshuaj - Tshuaj Kho Mob

Zoo Siab

Dupilumab txhaj tshuaj yog siv los kho cov tsos mob ntawm daim tawv nqaij mob (atopic dermatitis; yog ib daim tawv nqaij ua rau daim tawv nqaij qhuav thiab khaus thiab qee zaum muaj liab, ua pob liab vog rau cov laus thiab cov menyuam 6 xyoo thiab laus dua uas tsis tuaj yeem siv lwm yam tshuaj rau lawv mob lossis nws qhov mob eczema tsis tau teb rau lwm yam tshuaj. Nws kuj tseem siv nrog rau lwm cov tshuaj los tiv thaiv hawb pob, ua pa luv, hnoos, thiab lub hauv siab nruj vim qee yam mob hawb pob hauv cov neeg laus thiab cov menyuam 12 xyoo thiab laus dua uas nws cov tsos mob tsis tswj nrog lwm cov tshuaj. Dupilumab txhaj tshuaj tseem siv nrog rau lwm cov tshuaj los kho tus mob rhinosinusitis nrog rau lub qhov ntswg polyposis (tsis tu ncua lub qhov ntswg, mob ntshav ntswg thiab / lossis qhov ntswg txhaws, nrog lossis tsis txo qhov hnov ​​tsw lossis hnov ​​mob thiab mob rau lub ntsej muag) hauv cov neeg laus uas muaj cov tsos mob tsis tswj nrog lwm cov tshuaj. Dupilumab txhaj tshuaj yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua monoclonal tiv thaiv kab mob. Nws ua haujlwm los ntawm kev txiav tseg qhov kev nqis tes ua ntawm qee yam tshuaj hauv lub cev uas ua rau cov tsos mob ntawm daim tawv nqaij.


Dupilumab txhaj tshuaj tuaj tau los ua koob tshuaj ua kom zoo thiab lub npiv nkag los txhaj tshuaj subcutaneously (hauv qab daim tawv nqaij). Txog kev kho tus mob eczema rau cov laus, feem ntau yog txhaj ob koob (txhaj) rau thawj koob tshuaj, tom qab ntawv txhaj ib 2 zaug ib lub lis piam. Txog kev kho mob eczema rau cov menyuam muaj hnub nyoog 6 txog 17 xyoo, feem ntau yog txhaj ob koob rau thawj koob tshuaj, tom qab ntawd yuav hno ib zaug 2 mus rau 4 asthiv nyob ntawm tus menyuam qhov hnyav. Txog kev kho mob hawb pob hauv cov neeg laus thiab menyuam yaus 12 xyoos thiab laus dua, feem ntau yog txhaj ob koob tshuaj rau thawj koob tshuaj, tom qab ntawv txhaj ib 2 zaug ib lub lis piam. Txog kev kho mob ntawm tus mob rhinosinusitis nrog rau lub qhov ntswg polyposis hauv cov neeg laus, nws ib txwm txhaj ib koob txhua 2 lis piam. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Siv dupilumab txhaj tshuaj raws nraim li qhia. Tsis txhob txhaj ntau dua lossis ntau dua lossis txhaj nws ntau dua li cov kws khomob tau txib.


Yog tias koj siv dupilumab thiab mob hawb pob, txuas ntxiv noj lossis siv lwm yam tshuaj uas koj tus kws kho mob tau hais txog los kho koj tus mob hawb pob. Tsis txhob tsum tsis txhob noj koj cov tshuaj lossis hloov cov tshuaj ntawm ib qho ntawm koj cov tshuaj tshwj tsis yog koj tus kws kho mob hais kom koj yuav tsum. Dupilumab txhaj tshuaj yuav pab tiv thaiv kom txhob muaj mob hawb pob tab sis yuav tsis nres hawb pob uas twb tau pib mob lawm. Tsis txhob siv tshuaj dupilumab thaum lub sijhawm mob hawb pob. Koj tus kws kho mob yuav sau ntawv tawm lub tshuaj txau siv thaum lub caij muaj mob hawb pob.

Tej zaum koj yuav tau txais koj thawj koob tshuaj dupilumab hauv koj tus kws kho mob lub chaw haujlwm. Tom qab ntawd, koj tus kws kho mob yuav cia koj lossis tus neeg saib xyuas ua qhov kev txhaj tshuaj nyob hauv tsev. Ua ntej koj siv cov tshuaj dupilumab txhaj tshuaj rau koj tus kheej thawj zaug, nyeem cov lus ntawm cov kws tsim khoom rau tus neeg mob uas tuaj nrog cov tshuaj. Nug koj tus kws kho mob lossis kws muag tshuaj kom qhia koj lossis tus neeg uas yuav muab tshuaj rau yuav muab tshuaj li cas.

Siv ib leeg thiab xaum ib zaug xwb. Muab cov phwj uas siv coj los pov rau hauv lub khob uas muaj cov tshuaj tiv thaiv. Tham nrog koj tus kws kho mob lossis kws muag tshuaj txog yuav ua li cas pov tseg cov thawv ntim tshuaj tiv thaiv.


Yog tias koj tab tom siv cov koob txhaj tshuaj los yog tshuaj txhuam uas tau muab tso hauv tub yees, muab cov kua muag tso rau ib qho chaw tiaj tus uas tsis tshem lub koob txhaj thiab cia nws sov rau hauv chav kub (30 feeb rau 200 mg prefilled koob txhaj tshuaj thiab 45 feeb rau 300 mg prefilled syringe lossis prefilled pen) ua ntej koj npaj txhij yuav hno cov tshuaj. Tsis txhob sim kom sov cov tshuaj los ntawm kev ua kom sov hauv microwave, tso nws rau hauv dej kub, lossis lwm txoj hau kev.

Tsis txhob muab rab koob xaum los yog ib tug cwj mem uas muaj cov tshuaj dupilumab.

Txhua zaus saib cov tshuaj dupilumab ua ntej txhaj tshuaj. Txheeb xyuas tias lub hnub tas sij hawm tsis dhau thiab cov kua muaj tseeb thiab tsis muaj kob lossis daj me ntsis. Cov kua yuav tsum tsis muaj cov pom tawm. Tsis txhob siv rab koob xaum los yog xaum yog tias nws tawg lossis tawg, yog tias nws tas sij hawm lossis khov, lossis yog tias cov kua tau huab lossis muaj cov khoom me me.

Koj tuaj yeem hno cov tshuaj txhaj dupilumab nyob txhua qhov chaw ntawm sab xub ntiag ntawm koj tus ncej (ceg sab qaum) lossis plab (plab) tshwj tsis yog koj lub pij ntaws thiab thaj chaw 2 ntiv (5 centimeters) nyob ib ncig ntawm nws. Yog tias cov neeg zov me nyuam txhaj tshuaj, cov nraub qaum sab tes kuj tseem siv tau. Txo txoj kev pheej hmoo ntawm qhov mob lossis liab lossis khaus, siv qhov chaw sib txawv rau txhua qhov kev txhaj tshuaj. Tsis txhob txhaj rau thaj chaw uas tawv nqaij tawv nqaij, nqaij tawv, liab, lossis tawv lossis qhov uas koj muaj nti lossis ncab.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej siv cov tshuaj dupilumab,

  • qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau dupilumab, lwm yam tshuaj noj, lossis ib qho twg hauv kev txhaj tshuaj dupilumab. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais ib yam ntawm cov lus hauv qab no: qhov ncauj los yog nqus tau cov tshuaj corticosteroid xws li dexamethasone, methylprednisolone (Medrol), thiab prednisone (Rayos). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • qhia rau koj tus kws kho mob yog tias koj muaj lossis puas tau muaj teeb meem qhov muag, lossis yog tias koj muaj viav vias, cua nab, cua daj cua dub, lossis hlab pas (kis nrog cov cua nab uas nyob hauv lub cev).Yog tias koj tau txais kev mob dupilumab rau kev kho mob ntawm atropic dermatitis, qhia koj tus kws kho mob yog tias koj tseem muaj mob hawb pob.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj xeeb tub thaum siv cov tshuaj txhaj dupilumab, hu rau koj tus kws kho mob.
  • Nug koj tus kws kho mob seb koj puas yuav tsum tau txhaj tshuaj tiv thaiv kab mob. Tsis txhob txhaj tshuaj tiv thaiv kab mob thaum lub sijhawm kho koj tus mob yam tsis tas tham nrog koj tus kws kho mob.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Yog tias koj tsis nco qab txhaj koob tshuaj dupilumab, hno koj cov koob tshuaj sai li sai tau thaum koj nco qab nws thiab rov pib dua koj lub sijhawm. Txawm li cas los xij, yog tias nws tshaj 7 hnub tom qab koj tsis nco qab noj lawm, hla ncua lub koob tshuaj uas tsis nco qab lawm thiab txuas ntxiv rau koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob siv ob koob tshuaj los ua rau qhov ploj lawm. Hu rau koj tus kws kho mob yog tias koj tsis nco qab noj tshuaj thiab muaj lus nug txog yuav ua li cas.

Dupilumab txhaj tshuaj tuaj yeem ua rau phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • liab lossis mob ntawm thaj chaw txhaj tshuaj
  • caj pas mob
  • qhov ncauj lossis qhov ncauj tawm

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:

  • cov teeb meem tshiab lossis qhov muag tsis zoo, suav nrog qhov mob qhov muag, qhov muag plooj, liab lossis liab qhov muag, liab daim tawv muag liab lossis o, lossis hloov lub zeem muag
  • xoo pob, ua pa luv, kub ib ce, mob hauv siab, hnov ​​pins thiab koob, lossis qog ntawm caj npab lossis txhais ceg

Yog tias koj muaj cov tsos mob no, tsum tsis txhob siv tshuaj dupilumab thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

  • o ntawm lub ntsej muag, tawv muag, nplaig, lossis caj pas
  • o cov qog ntshav o
  • teeb meem nqos lossis ua pa
  • nruj hauv siab hauv siab lossis caj pas
  • khaus
  • ua pob
  • khaus
  • tsaus muag, kiv taub hau, lossis hnov ​​mob taub hau
  • mob tej pob txha
  • tiaj, ruaj, kub, liab thiab mob tawv nqaij qog
  • ua npaws

Dupilumab txhaj tshuaj tuaj yeem ua lwm cov phiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum siv cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub thauv ntim nws tau nkag hauv, kaw lub taub hau, thiab ncav tsis cuag cov menyuam. Khaws cov tshuaj txhaj rau dupilumab tso rau hauv tub yees lossis hauv chav sov txog li 14 hnub. Tsis khov. Khaws cov phwj tshuaj thiab cov xaum rau hauv lawv cov thawv qub los tiv thaiv lawv ntawm lub teeb.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij ntsib nrog koj tus kws kho mob.

Tsis txhob cia lwm tus siv koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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