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How Methylnaltrexone (Relistor) Works
Daim Duab: How Methylnaltrexone (Relistor) Works

Zoo Siab

Methylnaltrexone yog siv los kho kev cem quav los ntawm kev siv tshuaj opioid (narcotic) mob rau cov neeg muaj mob ntev (tsis tu ncua) uas tsis yog mob qog nqaij hlav tab sis kuj yuav cuam tshuam nrog kev mob qog noj ntshav lossis kev kho mob qog noj ntshav yav dhau los. Methylnaltrexone nyob hauv chav kawm ntawm cov tshuaj hu ua peripherally acting mu-opioid receptor antagonists. Nws ua haujlwm los ntawm kev tiv thaiv lub plab hnyuv los ntawm cov teebmeem ntawm kev siv tshuaj opioid (narcotic).

Methylnaltrexone los ua ib ntsiav tshuaj los noj ntawm qhov ncauj. Nws feem ntau noj ib hnub ib zaug nrog dej, tsawg kawg 30 feeb ua ntej noj mov thawj hnub. Siv tshuaj methylnaltrexone nyob rau tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj tshuaj methylnaltrexone raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Methylnaltrexone yuav tsum tau noj los ntawm cov neeg uas noj tshuaj opioid (narcotic). Tham nrog koj tus kws kho mob yog tias koj hloov pauv ntau npaum li cas lossis pes tsawg zaus koj noj koj cov tshuaj opioid. Yog tias koj tsum tsis noj tshuaj opioid, koj yuav tsum tsis txhob siv tshuaj methylnaltrexone ib yam nkaus.


Koj yuav tsum tsis txhob noj lwm yam tshuaj laxative thaum koj pib noj cov tshuaj methylnaltrexone. Txawm li cas los xij, nco ntsoov qhia koj tus kws kho mob paub yog tias methylnaltrexone tsis ua haujlwm rau koj tom qab noj nws rau 3 hnub. Koj tus kws kho mob yuav hais kom koj noj lwm cov tshuaj laxative.

Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia txog cov neeg mob rau koj (Kev Qhia Tshuaj Kho Mob) thaum koj pib kho nrog methylnaltrexone thiab txhua zaus koj rov ntim tshuaj rau koj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib zaub mov thiab Tshuaj (FDA) lub vev xaib (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kom tau Phau Ntawv Qhia Tshuaj.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj cov tshuaj methylnaltrexone,

  • qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau methylnaltrexone, lwm yam tshuaj noj, lossis lwm yam tshuaj hauv methylnaltrexone ntsiav tshuaj. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: alvimopan (Entereg), naldemedine (Symproic), naloxegol (Movantik), naloxone (Evzio, Narcan, hauv Bunavail, Suboxone, Zubsolv), lossis naltrexone (Vivitrol, hauv Contrave, Embeda). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • qhia rau koj tus kws kho mob yog tias koj tau ua lossis tau muaj mob plab hnyuv txhaws (txhaws hauv koj txoj hnyuv). Tej zaum koj tus kws khomob yuav qhia koj kom tsis txhob haus tshuaj methylnaltrexone.
  • qhia rau koj tus kws kho mob yog tias koj muaj lossis puas tau muaj teeb meem lub plab lossis lub plab zom mov nrog rau lub plab ua kiav txhab (ua mob rau hauv plab sab hauv), mob cancer ntawm lub plab lossis lub plab hnyuv, Crohn's mob (mob uas lub cev tawm tsam rau lub plab zom mov , ua rau mob, raws plab, poob phaus, thiab kub taub hau), diverticulitis (mob me me hauv ob sab phlu txoj hnyuv uas tuaj yeem ua rau mob), Ogilvie's syndrome (mob uas muaj mob hauv plab), lossis lub raum lossis mob siab kab mob.
  • qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav ua kom cev xeeb tub.Yog hais tias koj cev xeeb tub thaum siv methylnaltrexone, hu rau koj tus kws kho mob. Yog tias koj siv tshuaj methylnaltrexone thaum koj cev xeeb tub, koj tus menyuam yuav muaj tsos mob opioid tshem tawm.
  • qhia rau koj tus kws kho mob yog tias koj pub mis niam rau menyuam. Tsis txhob pub mis rau menyuam mos thaum koj tab tom noj tshuaj methylnaltrexone.
  • koj yuav tsum paub tias neeg feem coob mob plab hnyuv nyob hauv ob peb feeb txog rau ob peb teev tom qab siv tshuaj methylnaltrexone. Nco ntsoov tias koj nyob ze chav dej thaum koj noj cov tshuaj no.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.


Hla lub tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Methylnaltrexone tuaj yeem tshwm sim phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • ntuav
  • hws
  • ua daus no
  • ntxhov siab
  • yaw
  • mob taub hau
  • mob plab thiab o
  • mob leeg pob txha
  • los ntswg

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no, tsum tsis txhob siv tshuaj methylnaltrexone thiab hu rau koj tus kws kho mob tam sim ntawd:

  • raws plab heev
  • mob plab heev

Methylnaltrexone tuaj yeem ua rau muaj kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).


Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej). Yog tias koj cov tshuaj tuaj nrog desiccant canister (cov canister me me uas muaj cov tshuaj uas nqus cov dej noo kom cov tshuaj kom qhuav), tawm hauv lub pas dej mus rau hauv lub raj mis.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

  • kiv kiv, kiv taub hau, thiab tsaus muag thaum koj sawv nrawm dua los ntawm ib txoj hauj lwm dag
  • ua daus no
  • hws
  • los ntswg
  • zawv plab
  • mob plab
  • ntxhov siab
  • yaw
  • txo qis hauv kev mob txo qis mob los ntawm kev siv tshuaj opioid

Khaws tag nrho cov kev teem caij ntsib nrog koj tus kws kho mob.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Ntsig®
Kawg Kho - 05/15/2018

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