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INH and Rifapentine Treatment for LTBI
Daim Duab: INH and Rifapentine Treatment for LTBI

Zoo Siab

Rifapentine yog siv nrog lwm cov tshuaj los kho tus mob ntsws (active TB uas ua rau mob ntsws thiab qee zaum lwm qhov hauv lub cev) hauv cov neeg laus thiab cov menyuam hnub nyoog 12 xyoos thiab laus dua. Rifapentine tseem tseem siv nrog isoniazid (Laniazid) los kho cov neeg laus thiab menyuam yaus hnub nyoog 2 xyoos thiab laus dua nrog mob latent (so lossis nongrowing) TB, suav nrog cov neeg nyob ze nrog cov neeg uas muaj tus kab mob TB, kev sim tshuaj tuberculin ntawm daim tawv nqaij, tib neeg tus kab mob (HIV), lossis cov neeg muaj mob ntsws ntsig (txoj hlab ntsws ntawm lub ntsws tsis paub meej). Rifapentine yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua antimycobacterials. Nws ua haujlwm los ntawm tua cov kab mob uas ua rau kis tus kab mob.

Cov tshuaj tua kab mob xws li rifapentine yuav tsis ua haujlwm rau khaub thuas, mob khaub thuas, lossis lwm yam kis mob. Siv tshuaj tua kab mob thaum tsis siv tshuaj tiv thaiv kab mob ntxiv ua rau muaj kev pheej hmoo kis tus kab mob tuaj tom qab uas tiv thaiv kev kho mob tshuaj tua kab mob.

Rifapentine los ua ib ntsiav tshuaj noj ntawm qhov ncauj. Thaum rifapentine yog siv los kho tus mob active TB, feem ntau nws noj nrog zaub mov ob zaug ib asthiv, nrog koob tshuaj tsawg kawg 3 hnub sib nrug, rau thawj 2 hlis thiab tom qab ntawd ib zaug ib asthiv rau 4 hlis. Thaum rifapentine raug siv los kho kev mob ntsws latent, nws yuav tsum nrog zaub mov noj ib zaug txhua lub lim tiam. Siv phom phom nyob ib ncig ntawm tib lub sijhawm txhua hnub teem cia. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj phom ntev raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.


Yog tias koj tsis tuaj yeem nqos cov ntsiav tshuaj, koj tuaj yeem tsoo lawv thiab sib tov cov tshuaj hauv me me ntawm cov zaub mov semisolid xws li paj npleg lossis txiv apples. Nqos cov khoom sib tov tam sim ntawd; tsis txhob muab nws rau tom qab siv.

Txuas ntxiv noj cov tshuaj rifapentine kom txog thaum koj ua tiav cov tshuaj txawm tias koj xis neej dua, thiab ceev faj kom tsis txhob noj cov koob tshuaj. Yog tias koj tsum tsis txhob noj rifapentine sai sai, koj tus kab mob yuav kho tsis tau thiab tus kab mob yuav tiv taus tshuaj tua kab mob. Yog tias koj tsis nco qab cov tshuaj rifapentine, koj yuav muaj qhov tsis xis nyob lossis mob hnyav thaum koj pib rov qab noj tshuaj dua.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj cov tshuaj rifapentine,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau rifapentine, rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, hauv Rifamate, hauv Rifater), rifaximin (Xifaxan), lwm yam tshuaj noj, lossis lwm yam tshuaj hauv rifapentine ntsiav tshuaj. Nug koj tus kws muag tshuaj lossis tshawb xyuas Phau Ntawv Qhia Tshuaj Kho Mob rau cov npe ntawm cov khoom siv.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: cov tshuaj tua kab mob xws li chloramphenicol, ciprofloxacin (Cipro), clarithromycin (Biaxin, hauv Prevpac), dapsone, thiab doxycycline (Doryx, Monodox, Vibramycin, lwm tus); anticoagulants ('ntshav thinners') xws li warfarin (Coumadin, Jantoven); antifungals xws li fluconazole (Diflucan), itraconazole (Onmel, Sporanox), thiab ketoconazole; calcium channel blockers xws li diltiazem (Cardizem, Taztia, Tiazac, lwm tus), nifedipine (Adalat, Afeditab, Procardia), thiab verapamil (Calan, Covera, Verelan); clofibrate (Atromid-S; tsis muaj nyob hauv Asmeskas); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); digoxin (Lanoxin); disopyramide (Norpace); glyburide (Diabeta, Glynase); glipizide (Glucotrol); haloperidol (Haldol); Cov tshuaj tiv thaiv kab mob HIV; levothyroxine (Levoxyl, Synthroid, Tirosint); tshuaj txiav yeeb (Dolophine, Methadose); mexiletine, phenobarbital; phenytoin (Dilantin, Phenytek); prednisone (Rayos); propranolol (Hemangeol, Inderal, InnoPran); quinidine (hauv Nuedexta), quinine (Qualaquin); sildenafil (Revatio, Viagra); tacrolimus (Astagraf, Envarsus, Prograf); theophylline (Elixophyllin, Theochron, Uniphyl); tocainide (Tonocard; tsis muaj nyob hauv Asmeskas); thiab tricyclic cov tshuaj tiv thaiv kev ntxhov siab xws li amitriptyline thiab nortriptyline (Pamelor). Ntau lwm cov tshuaj tuaj yeem cuam tshuam nrog rifapentine, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • qhia rau koj tus kws kho mob yog tias koj noj lossis siv tshuaj tiv thaiv tshuaj hormonal (tshuaj muaj menyuam me, tshuaj pleev ib ce, ib ncig, pleev ib ce, thiab txhaj). Rifapentine tuaj yeem txo qis kev ua haujlwm ntawm kev sib deev hormonal. Koj yuav tsum siv lwm txoj kev tswj tsis pub muaj menyuam thaum siv cov tshuaj no. Tham nrog koj tus kws kho mob txog kev tswj tsis pub muaj menyuam thaum noj rifapentine.
  • qhia rau koj tus kws kho mob yog tias koj muaj tus kab mob TB nquag lossis koj tsis quav ntsej rau lwm cov tshuaj tua kab mob TB lossis yog tias koj muaj lossis tau muaj kab mob siab (mob rau qee yam khoom hauv nruab nrog cev tsim hauv lub cev thiab yuav ua rau mob plab, hloov kev xav thiab tus cwj pwm, lossis lwm yam tsos mob), tus kabmob HIV, lossis kab mob siab.
  • qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Yog tias koj xeeb tub thaum siv tshuaj rifapentine, hu rau koj tus kws kho mob.
  • tsis txhob pub mis noj thaum siv tshuaj rifapentine. Rifapentine yuav ua rau lub mis hloov mus ua xim liab-txiv kab ntxwv.
  • qhia koj tus kws kho mob yog tias koj coj tsom iav muag lossis lo hniav looj. Rifapentine yuav ua rau muaj xim liab nyob rau ntawm koj qhov chaw looj lossis lo hniav looj tas li.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.


Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Rifapentine yuav ua rau muaj kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • tawv nqaij ib ntus (xim daj, xim liab-txiv kab ntxwv, los yog xim av) ntawm koj cov tawv nqaij, hniav, qaub ncaug, zis, tso quav, tawm hws, thiab kua muag
  • kiv taub hau
  • tsaus muag
  • nce hws

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no, hu rau koj tus kws kho mob:

  • raws plab (txog li 2 hlis tom qab kho koj tus mob)
  • ua pob
  • khaus
  • khaus
  • hnoos nrog hawb pob
  • ua pa nyuaj
  • qhov muag liab, khaus, lossis khaus
  • ua npaws
  • hlwv
  • hloov kev xav thiab tus cwj pwm
  • o ntawm lub qhov muag, ntsej muag, daim di ncauj, tus nplaig, caj pas, caj npab, tes, taw, pob taws, lossis ceg qis
  • lub plawv dhia ceev lossis ceev
  • xeev siab
  • ntuav
  • mob hauv siab
  • cov tsos mob khaub thuas xws li ua npaws, ua daus no, mob ib ce, mob nqaij, nkees, thiab mob tob hau
  • mob plab
  • tsis qab los noj mov
  • tsaus zis
  • mob pob qij txha los yog o
  • daj ntawm daim tawv nqaij lossis qhov muag

Rifapentine tuaj yeem ua rau lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.


Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

  • ntshav hauv zis
  • khaus
  • lub cev mob los yog txhav

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj yam kuaj sim koj lub cev teb rau rifapentine.

Ua ntej muaj kev sim ntsuas, qhia rau koj tus kws kho mob thiab cov neeg ua haujlwm hauv chav kuaj pom tias koj noj tshuaj phom.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Txiv plig®
Kawg Kho - 04/15/2019

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