Tshuaj Romidepsin

Zoo Siab

• Ua ntej tau txais kev txhaj tshuaj romidepsin,
• Romidepsin txhaj tshuaj tuaj yeem tsim cov kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no, hu rau koj tus kws kho mob:

Romidepsin txhaj tshuaj yog siv los kho qhov mob cutaneous T-cell lymphoma (CTCL; ib pawg ntawm cov qog nqaij hlav ntawm lub cev tiv thaiv kab mob uas tshwm sim ua pob khaus tawv nqaij) hauv cov neeg uas twb tau kho nrog tsawg kawg ib yam tshuaj noj. Romidepsin txhaj tshuaj tseem yog siv los kho mob peripheral T-cell lymphoma (PTCL; ib hom ntawm tsis-Hodgkin's lymphoma) hauv cov neeg uas twb tau kho nrog tsawg kawg yog lwm yam tshuaj. Romidepsin txhaj tshuaj yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua histone deacetylase (HDAC) inhibitors. Nws ua haujlwm los ntawm kev ua kom qeeb qeeb ntawm kev mob hlwb.

Romidepsin txhaj tshuaj los ua cov hmoov los tov nrog kua los txhaj rau ntshav (rau hauv cov leeg ntshav) ntev li 4 teev los ntawm tus kws kho mob lossis kws saib xyuas neeg mob. Feem ntau nws muab rau hnub 1, 8, thiab 15 ntawm 28-hnub voj voog. Lub voj voog no yuav rov ua dua yog tias cov tshuaj tseem ua haujlwm thiab tsis ua rau muaj kev phiv loj.

Tham nrog koj tus kws kho mob txog cov kev mob tshwm sim thaum koj mus kho mob nrog tshuaj romidepsin. Yog tias koj muaj tej kev mob tshwm sim loj heev, koj tus kws kho mob yuav txiav koj txoj kev kho mob mus tas ib txhis lossis ib ntus thiab / lossis tej zaum yuav txo qhov koj cov koob tshuaj.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej tau txais kev txhaj tshuaj romidepsin,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau kev txhaj tshuaj romidepsin, lwm yam tshuaj noj, lossis ib qho twg ntawm kev txhaj tshuaj romidepsin. Nug koj tus kws muag tshuaj lossis tshawb xyuas cov ntaub ntawv ntawm tus neeg mob rau cov npe ntawm cov khoom sib xyaw.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: qee yam tshuaj tua kab mob xws li clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Erythrocin), moxifloxacin (Avelox), thiab telithromycin (Ketek); anticoagulants (cov ntshav ua haujlwm txawv) xws li warfarin (Coumadin, Jantoven); antifungals xws li itraconazole (Sporanox), ketoconazole (Nizoral), thiab voriconazole (Vfend); cisapride (Propulsid) (tsis muaj nyob hauv Asmeskas); dexamethasone; cov tshuaj rau tib neeg cov tshuaj tiv thaiv kab mob (HIV) xws li atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (hauv Kaletra, Norvir), thiab saquinavir (Invirase); cov tshuaj noj rau lub plawv tsis xwm yeem xws li amiodarone (Cordarone), disopyramide (Norpace), dofetilide (Tikosyn), procainamide (Procanbid, Pronestyl), quinidine (Quinidex), thiab sotalol (Betapace, Betapace AF); qee yam tshuaj rau qaug dab peg xws li carbamazepine (Epitol, Equetro, Tegretol), phenobarbital, thiab phenytoin (Dilantin); nefazodone; pimozide (Orap); rifabutin (Mycobutin); rifampin (Rifadin, hauv Rifamate, hauv Rifater, Rimactane); rab phom loj (Priftin); sparfloxacin (Zagam); lossis thioridazine (Mellaril). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm cov tshuaj yuav tuaj yeem cuam tshuam nrog kev txhaj tshuaj romidepsin, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob rau hauv daim ntawv no.
• qhia koj tus kws kho mob tias yam tshuaj ntsuab koj noj, tshwj xeeb tshaj yog St. John wort.
• qhia rau koj tus kws kho mob yog tias koj muaj xeev ntuav, ntuav, lossis zawv plab ua ntej koj pib kho nrog kev txhaj tshuaj romidepsin. Kuj qhia koj tus kws kho mob yog tias koj tau lossis puas tau muaj lub sijhawm QT ntev (qhov teeb meem tsis tshua muaj lub plawv uas yuav ua rau lub plawv dhia tsis xwm yeem, tsaus muag, lossis cia li tuag kiag), lub plawv dhia tsis xwm yeem lossis nrawm, ntau dhau los yog tsawg dhau potassium lossis magnesium hauv koj cov ntshav. , kab mob siab B (HBV; tus kab mob kis rau lub siab thiab muaj peev xwm ua rau lub siab puas lossis mob rau daim siab), Epstein Barr virus (EBV; tus kab mob herpes uas ua rau mob mononucleosis thiab cuam tshuam nrog qee yam mob qog nqaij hlav), lossis mob siab, mob raum, lossis kab mob plawv.
• qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Koj tus kws kho mob yuav kuaj xyuas saib koj puas xeeb tub ua ntej koj pib kho koj. Koj yuav tsum siv kev tswj tsis pub muaj menyuam kom tiv thaiv kev xeeb tub thaum koj kho mob los ntawm kev txhaj tshuaj romidepsin thiab tsawg kawg ib hlis tom qab koj koob kawg. Txawm li cas los xij, koj yuav tsum tsis txhob siv cov tshuaj tiv thaiv cev xeeb tub (estrogen) (tshuaj txwv, tshuaj pleev ib ce, ib ncig, pleev lossis txhaj) vim tias kev txhaj tshuaj romidepsin tuaj yeem txwv cov tshuaj no tsis ua haujlwm raws li lawv yuav tsum tau ua. Yog tias koj yog tus txiv neej nrog tus poj niam tus poj niam uas tuaj yeem cev xeeb tub, nco ntsoov siv cov tshuaj tiv thaiv kom tsis txhob muaj menyuam thaum lub sijhawm kho nrog cov tshuaj vwm thiab tsawg kawg ib hlis tom qab koj koob kawg. Tham nrog koj tus kws kho mob txog kev tswj tsis pub muaj menyuam uas koj tuaj yeem siv. Yog tias koj xeeb tub thaum tau txais kev txhaj tshuaj romidepsin, hu rau koj tus kws kho mob. Txhaj tshuaj Romidepsin tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab. Koj yuav tsum tsis txhob pub niam mis rau lub sijhawm koj tau txais kev kho mob nrog kev txhaj tshuaj romidepsin thiab tsawg kawg 1 asthiv tom qab koj koob zaum kawg.
• yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav tias koj tau txais kev txhaj tshuaj romidepsin.

Nco ntsoov haus dej kom ntau li tsawg kawg 3 hnub tom qab txhaj txhua koob tshuaj romidepsin.

Tham nrog koj tus kws kho mob txog kev noj txiv kab ntxwv qaub thiab haus kua txiv txiv qaub thaum tau txais cov tshuaj no.

Romidepsin txhaj tshuaj tuaj yeem tsim cov kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• xeev siab
• ntuav
• zawv plab
• cem quav
• mob plab
• qhov ncauj tawm
• mob taub hau
• hloov kev nkag siab ntawm saj
• tsis qab los noj mov
• khaus

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no, hu rau koj tus kws kho mob:

• nkees lossis qaug zog
• daj ntseg tawv nqaij
• txog siav
• mob hauv siab
• lub plawv dhia tsis xwm yeem
• zoo li kiv tob hau lossis tsaus muag
• yooj yim bruising los yog los ntshav
• kub ib ce, hnoos, zoo li mob khaub thuas, mob ib ce, mob rau tso zis, mob tawv nqaij, thiab muaj lwm yam tsos mob ntawm kis (tej zaum yuav tshwm sim txog li 30 hnub tom qab koj tau txais kev kho mob)
• ua pob
• blistering lossis tev tawv nqaij
• o ntawm tes, taw, pob taws, lossis ceg qis

Romidepsin txhaj tshuaj tuaj yeem tsim teeb meem kev tsis tuaj yeem. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev tau txais cov tshuaj no yog tias koj xav tau menyuam.

Romidepsin txhaj tshuaj tuaj yeem tsim lwm cov kev phiv tshuaj. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum tau txais cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee qhov kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau kev txhaj tshuaj romidepsin.

Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev txhaj tshuaj romidepsin.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Istodax^®