Lopinavir thiab Ritonavir

Zoo Siab

• Ua ntej noj lopinavir thiab ritonavir,
• Lopinavir thiab ritonavir yuav ua rau muaj kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob hauv qab no, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

Lopinavir thiab ritonavir tam sim no tau kawm hauv ntau qhov kev tshawb fawb txog kev kho mob rau tus kabmob coronavirus 2019 (COVID-19) ib leeg lossis nrog lwm cov tshuaj noj. Kev siv lopinavir thiab ritonavir rau kev kho mob ntawm COVID-19 tseem tsis tau tsim. Qee cov kws tshawb fawb muaj kev cia siab vim tias cov tshuaj no tau siv los kho kho tus kab mob sib xws.

Lopinavir thiab ritonavir yuav tsum coj TSUAS mus raws li tus kws kho mob tau qhia rau kev kho mob ntawm COVID-19.

Kev sib xyaw ntawm lopinavir thiab ritonavir yog siv nrog lwm cov tshuaj los kho tib neeg cov tshuaj tiv thaiv tus kabmob HIV (HIV). Lopinavir thiab ritonavir yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua protease inhibitors. Lawv ua haujlwm los ntawm kev txo qis hauv cov HIV hauv cov ntshav. Thaum lopinavir thiab ritonavir noj ua ke, ritonavir kuj pab ua kom muaj qhov lopinavir ntau ntxiv hauv lub cev kom cov tshuaj muaj txiaj ntsig zoo dua. Txawm hais tias lopinavir thiab ritonavir yuav tsis kho HIV, cov tshuaj no yuav txo koj txoj hmoo los ntawm kev tiv thaiv kab mob (AIDS) thiab mob ntsig txog HIV xws li mob hnyav lossis mob qog ntshav. Siv cov tshuaj no nrog rau kev xyaum pw ua ke kom nyab xeeb thiab hloov ua lwm yam hauv lub neej yuav txo qhov kev pheej hmoo kis tus mob HIV mus rau lwm tus neeg.

Kev sib xyaw ntawm lopinavir thiab ritonavir los ua ib ntsiav tshuaj thiab ib qho tov (kua) los noj ntawm qhov ncauj. Nws feem ntau yog noj ob zaug ib hnub, tab sis tej zaum yuav noj ib zaug ib hnub los ntawm qee cov neeg laus. Kev daws yuav tsum tau noj nrog zaub mov. Cov ntsiav tshuaj tuaj yeem noj nrog lossis tsis noj mov. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj lopinavir thiab ritonavir raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Nqos cov ntsiav tshuaj tag nrho; tsis txhob sib faib, zom, lossis tsoo lawv.

Yog tias koj tab tom siv txoj kev daws teeb meem, co nws zoo ua ntej txhua qhov kev siv los tov tshuaj kom zoo ib yam. Siv rab koob-ntsuas diav lossis khob kom ntsuas qhov tseeb ntawm cov kua rau txhua koob, tsis yog ib rab diav hauv tsev ib txwm siv.

Txuas ntxiv noj cov lopinavir thiab ritonavir txawm tias koj xis neej. Tsis txhob tsum noj lopinavir thiab ritonavir tsis tas tham nrog koj tus kws kho mob. Yog tias koj tsis nco qab noj ntau dua, noj tsawg dua li cov tshuaj noj, lossis tsum tsis noj lopinavir thiab ritonavir, koj tus mob yuav nyuaj kho.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj lopinavir thiab ritonavir,

• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau lopinavir, ritonavir (Norvir), lwm yam tshuaj noj, lossis lwm yam tshuaj hauv lopinavir thiab ritonavir ntsiav tshuaj lossis tshuaj daws. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob yog tias koj noj ib qho tshuaj hauv qab no: alfuzosin (Uroxatral); apalutamide (Erleada); cisapride (Propulsid) (tsis muaj nyob hauv Asmeskas); colchicine (Colcrys, Mitigare) hauv cov neeg muaj lub raum lossis kab mob siab; dronedarone (Multaq); elbasvir thiab grazoprevir (Zepatier); cov tshuaj ergot xws li dihydroergotamine (D.H.E. 45, Migranal), ergotamine (Ergomar, hauv Cafergot, hauv Migergot), thiab methylergonovine (Methergine); lomitapide (Juxtapid); lovastatin (Altoprev); lurasidone (Latuda); midazolam noj los ntawm qhov ncauj (Versed); pimozide (Orap); ranolazine (Ranexa); phom phom (Rimactane, Rifadin, hauv Rifamate, hauv Rifater); sildenafil (tsuas yog Revatio hom siv rau mob ntsws); simvastatin (Zocor, hauv Vytorin); St. John lub wort; lossis triazolam (Halcion). Koj tus kws kho mob yuav qhia koj kom tsis txhob noj lopinavir thiab ritonavir yog tias koj noj ib lossis ntau dua ntawm cov tshuaj no.
• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj tias lwm yam tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj noj vitamins, thiab khoom noj muaj txiaj ntsig koj noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: anticoagulants ('ntshav thinners') xws li warfarin (Coumadin, Jantoven) thiab rivaroxaban (Xarelto); cov tshuaj tiv thaiv xws li itraconazole (Onmel, Sporanox), isavuconazonium (Cresemba), ketoconazole (Nizoral), thiab voriconazole (Vfend); atovaquone (Mepron, hauv Malarone); bedaquiline (Sirturo); beta-blockers; bosentan (Tracleer); bupropion (Wellbutrin, Zyban, lwm tus); calcium-channel blockers xws li felodipine, nicardipine (Cardene), thiab nifedipine (Adalat, Afeditab CR, Procardia); cov roj uas txhaws tej tshuaj xws li atorvastatin (Lipitor, hauv Caduet), thiab rosuvastatin (Crestor); clarithromycin (Biaxin, hauv Prevpac); digoxin (Lanoxin); elagolix (Orilissa); fentanyl (Actiq, Duragesic, Onsolis, lwm tus); fosamprenavir (Lexiva); qee yam tshuaj rau mob qog noj ntshav xws li abemaciclib (Verzenio), dasatinib (Sprycel), encorafenib (Braftovi), ibrutinib (Imbruvica), ivosidenib (Tibsovo), neratinib (Nerlynx), nilotinib (Tasigna), venetoclax (Venclexta), ; qee yam tshuaj rau lub plawv dhia tsis xwm yeem xws li amiodarone (Cordarone, Nexterone, Pacerone), bepridil (tsis muaj nyob hauv Asmeskas; Vascor), lidocaine (Lidoderm; hauv Xylocaine nrog Epinephrine), thiab quinidine (hauv Nuedexta); qee cov tshuaj rau kab mob siab hom C (HCV) xws li boceprevir (Victrelis; tsis muaj nyob hauv Asmeskas); glecaprevir thiab pibrentasvir (Mavyret); simeprevir (tsis muaj nyob hauv U.S.; Olysio); sofosbuvir, velpatasvir, thiab voxilaprevir (Sovaldi, Epclusa, Vosevi); thiab paritaprevir, ritonavir, ombitasvir, thiab / lossis dasabuvir (Viekira Pak); qee cov tshuaj rau qhov qaug dab peg xws li carbamazepine (Equetro, Tegretol, Teril, lwm tus), lamotrigine (Lamictal), phenobarbital, phenytoin (Dilantin, Phenytek), thiab valproate; cov tshuaj noj uas ua rau lub cev txo qis xws li cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), thiab tacrolimus (Astagraf, Prograf); tshuaj txiav yeeb (Dolophine, Methadose); qhov ncauj los yog nqus tshuaj steroids xws li betamethasone, budesonide (Pulmicort), ciclesonide (Alvesco, Omnaris), dexamethasone, fluticasone (Flonase, Flovent, hauv Advair), methylprednisolone (Medrol), mometasone (hauv Dulera). prednisone (Rayos), thiab triamcinolone; lwm cov tshuaj tiv thaiv kab mob xws li abacavir (Ziagen, hauv Epzicom, hauv Trizivir, lwm tus); atazanavir (Reyataz, nyob rau hauv Evotaz), delavirdine (Rescriptor), efavirenz (Sustiva, hauv Atripla), indinavir (Crixivan), maraviroc (Selzentry), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norv), (Viread, hauv Atripla, hauv Truvada), tipranavir (Aptivus), saquinavir (Invirase), thiab zidovudine (Retrovir, hauv Combivir, hauv Trizivir); quetiapine (Seroquel); rifabutin (Mycobutin); salmeterol (Serevent, hauv Advair); sildenafil (Viagra); tadalafil (Adcirca, Cialis); trazodone; thiab vardenafil (Levitra). Yog tias koj siv cov tshuaj hauv qhov ncauj, tseem qhia rau koj tus kws kho mob yog tias koj noj disulfiram (Antabuse) lossis metronidazole (Flagyl, hauv Nuvessa, hauv Vandazole). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• yog tias koj noj didanosine, noj nws 1 teev ua ntej lossis 2 teev tom qab koj noj lopinavir thiab ritonavir tov nrog zaub mov. Yog tias koj noj lopinavir thiab ritonavir ntsiav tshuaj, koj tuaj yeem coj lawv ntawm lub plab khoob thaum tib lub sijhawm koj noj didanosine.
• qhia rau koj tus kws kho mob yog tias koj muaj lossis puas tau muaj lub sijhawm QT ntev (qhov teeb meem tsis tshua muaj lub plawv uas yuav ua rau lub plawv dhia tsis xwm yeem, tsaus muag, lossis cia li tuag kiag), lub plawv dhia tsis xwm yeem, cov poov tshuaj muaj tsawg hauv koj cov ntshav, hemophilia, cov roj ntshav siab lossis triglycerides (rog) nyob rau hauv cov ntshav, pancreatitis (o ntawm tus txiav), lossis mob siab lossis mob siab.
• koj yuav tsum paub tias lopinavir thiab ritonavir tuaj yeem txo qhov kev ua haujlwm zoo tshaj plaws ntawm kev sib deev hormonal (tshuaj txwv, thaj ua rau thaj, nplhaib lossis txhaj tshuaj). Tham nrog koj tus kws kho mob txog kev siv lwm txoj kev tswj tsis pub muaj menyuam.
• qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj lopinavir thiab ritonavir, hu rau koj tus kws kho mob. Koj yuav tsum tsis txhob pub mis niam yog tias koj kis nrog HIV lossis yog tias koj noj lopinavir thiab ritonavir.
• koj yuav tsum paub tias qee cov khoom xyaw hauv cov tshuaj lopinavir thiab ritonavir yuav ua rau muaj kev phom sij txaus ntshai thiab cuam tshuam rau lub neej ntawm cov menyuam mos. Lopinavir thiab ritonavir tshuaj yuav tsum tsis txhob muab rau cov menyuam hnub nyoog qis dua 14 hnub lossis cov menyuam mos hnub nyoog qis dua 14 hnub dhau los lawv hnub tas sijhawm, tshwj tsis yog tus kws kho mob xav tias muaj qhov laj thawj zoo rau tus menyuam tau txais qhov tshuaj zoo. tom qab yug. Yog tias koj tus menyuam tus kws kho mob xaiv muab cov tshuaj lopinavir thiab ritonavir rau koj tus menyuam tomqab yug tas, koj tus menyuam yuav tau txais kev saib xyuas zoo zoo txog cov kev phiv loj. Hu rau koj tus menyuam tus kws kho mob sai li sai tau yog tias koj tus menyuam tsaug zog lossis hloov pa ntawm lub sijhawm nws siv tshuaj lopinavir thiab tshuaj ritonavir.
• koj yuav tsum paub tias koj lub cev rog tuaj yeem nce lossis txav mus rau thaj chaw ntawm koj lub cev, xws li koj sab nraub qaum, caj dab ('' twm hump ''), ob lub mis, thiab ib puag ncig koj lub plab. Koj tuaj yeem pom ib qho ploj ntawm lub cev rog ntawm koj lub ntsej muag, ceg thiab caj npab.
• koj yuav tsum paub tias koj tuaj yeem ntsib hyperglycemia (nce hauv koj cov piam thaj hauv ntshav) thaum koj tseem noj cov tshuaj no, txawm tias koj tsis tau muaj ntshav qab zib. Qhia rau koj tus kws kho mob tam sim ntawd yog tias koj muaj cov tsos mob hauv qab no thaum koj noj lopinavir thiab ritonavir: nqhis dej heev, tso zis heev, tshaib heev, plooj tsis pom kev, lossis tsis muaj zog. Nws yog ib qho tseem ceeb heev uas yuav tau hu rau koj tus kws kho mob sai li sai tau uas koj muaj cov tsos mob no, vim tias cov ntshav qab zib uas tsis tau kho nws tuaj yeem ua rau mob hnyav hu ua ketoacidosis. Ketoacidosis tuaj yeem dhau los ua neeg muaj sia nyob yog tias tsis kho thaum ntxov. Cov tsos mob ntawm ketoacidosis suav nrog: qhov ncauj qhuav, xeev siab thiab ntuav, ua pa luv, ua pa uas hnov ​​tsw thiab tsis nco qab.
• koj yuav tsum paub tias thaum koj tab tom noj tshuaj los kho kab mob HIV, koj lub cev tiv thaiv kab mob yuav muaj zog thiab pib tawm tsam lwm yam kev mob uas twb muaj hauv koj lub cev lawm. Qhov no tuaj yeem ua rau koj tsim cov tsos mob ntawm cov mob ntawd. Yog tias koj muaj cov tsos mob tshiab lossis mob hnyav dua tom qab pib kho mob lopinavir thiab ritonavir, nco ntsoov qhia koj tus kws kho mob.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Lopinavir thiab ritonavir yuav ua rau muaj kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• tsis muaj zog
• zawv plab
• roj
• Kev mob siab
• poob phaus
• mob taub hau
• teeb meem tsis tsaug zog los yog pw tsaug zog
• mob leeg
• loog loog, hlawv, lossis kov hauv tes lossis taw
• mob plab, xeev siab thiab ntuav

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob hauv qab no, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

• xeev siab
• ntuav
• mob plab
• nkees heev
• tsis qab los noj mov
• mob hauv sab saud hauv plab
• daj ntawm daim tawv nqaij lossis qhov muag
• khaus tawv
• kiv taub hau
• lub teeb ci ntsa iab
• tsaus muag
• lub plawv dhia tsis xwm yeem
• hlwv
• ua pob

Lopinavir thiab ritonavir yuav ua rau muaj kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws cov ntsiav tshuaj ntawm chav sov thiab tiv thaiv lawv los ntawm kev ya raws. Nws yog qhov zoo tshaj plaws khaws cov ntsiav tshuaj rau hauv lub khob uas lawv tau nkag rau; yog tias koj yuav tsum nqa tawm ntawm lub thawv, koj yuav tsum siv lawv li ntawm 2 lub lis piam. Koj tuaj yeem khaws cov tshuaj ntawm qhov ncauj tso rau hauv tub yees kom txog thaum hnub tas sij hawm luam tawm ntawm daim ntawv lo, lossis koj tuaj yeem khaws nws rau hauv chav tsev kub txog li 2 hlis.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Nws yog ib qho tseem ceeb kom tau txais kev pab kho mob sai li sai tau yog tias tus menyuam haus ntau tshaj li qhov ib txwm siv ntawm cov tshuaj. Txoj kev daws teeb meem muaj dej cawv thiab lwm yam khoom xyaw ntau uas yuav ua rau muaj kev phom sij rau me nyuam.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau lopinavir thiab ritonavir.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Kaletra^® (muaj Lopinavir, Ritonavir)