Tus Sau: Gregory Harris
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Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects
Daim Duab: Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects

Zoo Siab

Dofetilide tuaj yeem ua rau koj lub siab ntaus tsis xwm yeem. Koj yuav tsum tau nyob hauv tsev kho mob lossis lwm qhov chaw uas koj tus kws kho mob tuaj yeem saib xyuas koj li 3 hnub thaum koj tau pib lossis pib dua ntawm dofetilide. Nws yog ib qho tseem ceeb yuav tau nyeem tus neeg mob cov ntaub ntawv tau muab rau koj txhua zaus koj pib kho nrog dofetilide.

Dofetilide yog siv los kho lub plawv dhia tsis xwm yeem (suav nrog atrial fibrillation lossis atrial flutter). Nws yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua antiarrhythmics. Nws txhim kho koj lub plawv atherosclerosis los ntawm relaxing ib qho kev nyiam lub plawv.

Dofetilide los ua tshuaj ntsiav los noj ntawm qhov ncauj. Nws feem ntau yog noj ob zaug ib hnub, tab sis tej zaum yuav noj ib zaug ib hnub nyob rau hauv cov neeg uas muaj qee yam mob. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj tshuaj dofetilide raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Dofetilide tswj hwm lub plawv tsis xwm yeem tab sis tsis kho lawv. Txuas ntxiv noj cov tshuaj dofetilide txawm hais tias koj tus kheej yuav xis nyob. Tsis txhob tsum tsis txhob noj cov tshuaj dofetilide yam tsis tham nrog koj tus kws kho mob.


Cov tshuaj no qee zaum sau tseg rau lwm qhov kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj cov tshuaj dofetilide,

  • qhia koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau dofetilide, lwm yam tshuaj noj, lossis ib qho twg hauv dofetilide tsiav tshuaj. Nug koj tus kws muag tshuaj lossis tshawb xyuas cov ntaub ntawv ntawm tus neeg mob rau cov npe ntawm cov khoom sib xyaw.
  • qhia koj tus kws kho mob yog tias koj noj cimetidine (Tagamet), dolutegravir (Tivicay), hydrochlorothiazide (Microzide, Oretic), hydrochlorothiazide thiab triamterene (Dyazide, Maxzide), ketoconazole (Nizoral), megestrol (Megace), prochlorperazine (Compro,) trimethoprim (Primsol), trimethoprim thiab sulfamethoxazole (Bactrim, Septra, Sulfatrim), thiab verapamil (Calan, Covera, Verelan). Koj tus kws kho mob yuav qhia koj kom tsis txhob noj tshuaj dofetilide yog tias koj noj ib lossis ntau dua ntawm cov tshuaj no.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais qee yam ntawm cov hauv qab no: amiloride (Midamor); cov tshuaj tua kab mob xws li erythromycin (E.E.S., E-Mycin) thiab norfloxacin (Noroxin); qee yam tshuaj tua kab mob xws li fluconazole (Diflucan), itraconazole (Sporanox), thiab ketoconazole (Nizoral); bepridil (Vascor); cannabinoids xws li dronabinol (Marinol), nabilone (Cesamet) lossis tshuaj maj (cannabis); digoxin (Lanoxin); diltiazem (Cardizem, Cartia XT, Dilacor XR, Taxtia XT, Tiazac); diuretics ('dej tshuaj'); HIV protease inhibitors suav nrog atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, hauv Kaletra), saquinavir (Invirase) thiab tipranavir (Aptivus); tshuaj noj rau mob ntsws xws li zafirlukast (Ua txhaum cai); tshuaj rau kev nyuaj siab, mob hlwb, lossis xeev siab; cov tshuaj noj rau lub plawv tsis xwm yeem xws li amiodarone (Cordarone, Pacerone); metformin (Fortamet, Glucophage, Glumetza, Riomet); nefazodone; lossis quinine (Qualquin).
  • qhia rau koj tus kws kho mob yog tias koj tau lossis muaj tus mob QT ntev dua (qhov mob uas yuav ua rau muaj kev pheej hmoo lub plawv tsis zoo uas yuav ua rau tsaus muag lossis cia li tuag kiag), lossis mob raum.
  • qhia rau koj tus kws kho mob yog tias koj muaj mob raws plab ntau dhau, tawm hws, ntuav, tsis qab los, los sis nqhis dej tsawg los yog muaj cov poov tshuaj tsawg nyob hauv koj cov ntshav, thiab yog tias koj muaj lossis koj tau muaj dua lub plawv lossis mob siab.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj dofetilide, hu rau koj tus kws kho mob.

Tham nrog koj tus kws kho mob txog kev noj txiv kab ntxwv qaub lossis haus kua txiv txiv qaub thaum noj dofetilide.


Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav txog sijhawm rau koj cov tshuaj txuas ntxiv, hla cov koob tshuaj ploj thiab txuas ntxiv koj cov sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Dofetilide yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • mob taub hau
  • mob hauv siab
  • txog siav
  • xeev siab
  • cov tsos mob khaub thuas zoo li
  • mob plab
  • rov qab mob
  • teeb meem tsis tsaug zog los yog pw tsaug zog

Yog tias koj muaj cov tsos mob nram qab no, hu rau koj tus kws kho mob tam sim ntawd:

  • ceev, pounding, los yog lub plawv dhia tsis xwm yeem
  • ua pob
  • raws plab heev
  • kiv tob hau lossis tsaus muag
  • tawm hws txawv txawv
  • ntuav
  • tsis qab los noj mov
  • nce nqhis dej (haus ntau dua li ib txwm)

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).


Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj lub plawv atherosclerosis yuav tsum kuaj xyuas tsis tu ncua los txiav txim koj cov lus teb rau dofetilide. Koj tus kws kho mob kuj tseem yuav xav ua raws li koj lub raum ua haujlwm thiab ntshav cov poov tshuaj kom ze thaum koj noj dofetilide.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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Kawg Kho - 01/15/2016

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