Malignant hyperthermia

Malignant hyperthermia (MH) yog ib yam kab mob uas ua rau lub cev kub ceev ceev thiab cov leeg mob nhyav heev thaum ib tus neeg nrog MH mob tshuaj loog. MH dhau los ntawm tsev neeg.

Hyperthermia txhais tau tias lub cev kub. Tus mob no tsis zoo li hyperthermia los ntawm kev kho mob maj nrawm xws li mob stroke tshav kub lossis kis kab mob.

MH yog pub muaj. Tsuas yog ib tug niam txiv muaj tus kabmob coj tus menyuam mus rau qhov muaj mob.

Nws yuav tshwm sim nrog qee lwm lwm yam kab mob muaj keeb, muaj ntau hom mob myopathy thiab cov kab mob tseem ceeb.

Cov tsos mob ntawm MH suav nrog:

• Ntshav
• Cov zis daj tsaus nti (vim yog cov leeg nqaij hu ua myoglobin hauv cov zis)
• Mob ib ce tsis hnov ​​tseeb, xws li ua kom tawm dag zog lossis raug mob
• Nqaij ua kom nruj thiab txhav
• Nce hauv lub cev kub txog 105 ° F (40.6 ° C) lossis siab dua

MH feem ntau pom tom qab ib tug neeg raug muab tshuaj loog thaum phais mob.

Tej zaum yuav muaj keeb kwm tsev neeg ntawm MH lossis qhia txog yam tuag thaum lub sij hawm ua tshuaj loog.

Tus neeg tej zaum yuav muaj lub siab ceev ceev thiab xwm yeem.

Kev ntsuam xyuas rau MH suav nrog:

• Kev tshawb fawb ntshav (PT, lossis lub sijhawm prothrombin; PTT, lossis lub sijhawm thromboplastin)
• Ntshav tshuaj lom neeg cov ntshav, nrog rau CK (creatinine kinase, uas ntau dua nyob rau hauv cov ntshav thaum cov leeg mob puas lawm thaum sib tw ntawm kev mob)
• Kev kuaj raws caj ces saib seb puas muaj raws li cov kab mob caj ceg muaj feem nrog tus kab mob
• Nqaij xyoob
• Zis myoglobin (cov leeg protein)

Thaum lub sijhawm kuaj mob MH, ib qho tshuaj hu ua dantrolene feem ntau muab. Qhwv tus neeg rau hauv daim pam txias yuav pab txo kev ua npaws thiab qhov muaj kev pheej hmoo loj heev.

Txhawm rau khaws cov raum ua haujlwm thaum lub sijhawm tsis sib haum xeeb, tus neeg yuav tau txais dej los ntawm txoj hlab ntshav.

Cov peev txheej no tuaj yeem muab cov ntaub ntawv qhia ntxiv txog MH:

• Malignant hyperthermia Koom Tes ntawm Tebchaws Asmeskas - www.mhaus.org
• Koom Haum Koom Tes rau Cov Kab Mob Tsis Txaus - rarediseases.org/rare-diseases/malignant-hyperthermia
• NIH Genetics Hauv Tsev Hais Txog - ghr.nlm.nih.gov/condition/malignant-hyperthermia

Rov ua dua los yog tsis kho dua qhov qub tuaj yeem ua rau lub raum tsis ua haujlwm. Yog tsis kho lub ntu nws tuaj yeem ua rau neeg tuag taus.

Cov teeb meem loj no tuaj yeem tshwm sim:

• Kev Sib Koom Siab
• Rhuav ntawm cov leeg mob
• O rau tes thiab taw thiab o teeb meem nrog ntshav ntws thiab lub paj hlwb kev ua haujlwm (qhov mob ua ke)
• Kev Tuag
• Txawv ntshav txhaws thiab los ntshav
• Lub plawv muaj teeb meem atherosclerosis
• Raum tsis ua haujlwm
• Buildup ntawm cov kua qaub hauv lub cev (kua hauv lub cev acid)
• Kev haus dej hauv lub ntsws
• Cov leeg tsis muaj zog lossis deformed (myopathy lossis cov leeg nqaij ua haujlwm)

Yog tias koj xav phais mob, qhia koj tus kws phais mob thiab kws kho mob tsaj tshuaj ua ntej kev phais mob yog tias:

• Koj paub tias koj lossis ib tus neeg hauv koj tsev neeg muaj teeb meem txog kev tso tshuaj kom tsaug zog
• Koj paub tias koj muaj keeb kwm ntawm tsev neeg MH

Siv qee yam tshuaj tuaj yeem tiv thaiv kev mob ntawm MH thaum phais mob.

Qhia koj tus kws kho mob ua ntej kev phais mob nrog tshuaj loog, yog tias koj lossis ib tus neeg hauv koj tsev neeg muaj MH.

Zam kev siv tshuaj yeeb tshuaj xws li yeeb dawb, tshuaj amphetamine (ceev), thiab ecstasy. Cov tshuaj no yuav tsim teeb meem zoo li MH hauv cov neeg uas ntxim rau tus mob no.

Kev tawm tswv yim rau caj ces tau raug pom zoo rau ib tus neeg uas muaj keeb kwm keeb kwm mob caj dab (myopathy), mob leeg nqaij, lossis MH.

Hyperthermia - malignant; Hyperpyrexia - malignant; MH

Asmeskas Koom Haum Saib Xyuas Kev Mob Hlwb Kev Mob. Malignant hyperthermia daws kev npaj thiab kev kho mob: lus qhia txoj hauj lwm. www.aana.com/docs/default-source/practice-aana-com-web-documents-(all)/malignant-hyperthermia-crisis-preparedness-and-treatment.pdf?sfvrsn=630049b1_8. Hloov kho thaum Lub Plaub Hlis 2018. Nkag mus rau Lub Tsib Hlis 6, 2019.

Kulaylat MN, Nruab Hnub MT. Kev phais mob ntxiv. Hauv: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Phau Ntawv Txog Kev Kho MobCov. 20 tus ed. Philadelphia, PA: Elsevier; 2017: chap 12.

Zhou J, Bose D, Allen PD, Pessah IN. Malignant hyperthermia thiab mob leeg-cuam tshuam. Hauv: Miller RD, ed. Miller lub tshuaj loogCov. 8 tus ed. Philadelphia, PA: Elsevier Saunders; Xyoo 2015: chap 43.