Neurosyphilis

Neurosyphilis yog ib tug kab mob kis rau lub hlwb los yog tus txha caj qaum. Feem ntau nws tshwm sim rau cov neeg uas tsis kho tus mob syphilis tau ntau xyoo.

Neurosyphilis tshwm sim los ntawm Treponema pallidumCov. Nov yog cov kab mob uas ua rau mob syphilis. Neurosyphilis feem ntau tshwm sim li 10 rau 20 xyoo tom qab tus neeg raug mob syphilis. Tsis yog txhua tus neeg muaj mob syphilis los kho qhov kev mob no.

Muaj plaub yam sib txawv ntawm cov neurosyphilis:

• Asymptomatic (feem ntau daim ntawv)
• Paresis dav dav
• Kev mob ntshav siab
• Cov ntxhuav dorsalis

Asymptomatic neurosyphilis tshwm sim ua ntej tsos mob syphilis. Asymptomatic txhais tau tias tsis muaj tsos mob dab tsi.

Cov tsos mob feem ntau cuam tshuam rau ntawm cov leeg hlwb. Nyob ntawm daim ntawv ntawm neurosyphilis, cov tsos mob yuav suav nrog ib qho hauv qab no:

• Taug kev txawv txav (gait), lossis tsis tuaj yeem taug kev
• Loog ntawm cov ntiv taw, taw, lossis ceg
• Teeb meem nrog kev xav, xws li kev tsis meej pem lossis tsis meej
• Teeb meem hlwb, xws li kev nyuaj siab lossis kev txob txob
• Mob taub hau, nriaj tes, lossis caj dab txhav
• Poob zais zis tswj (kev tswj tus kheej)
• Kev quaj ntsuag, lossis tsis muaj zog
• Pom teeb meem, dig muag

Koj tus kws kho mob yuav kuaj xyuas lub cev thiab yuav pom cov hauv qab no:

• Kev rov ua haujlwm tsis zoo
• Nqaij mob atrophy
• Cov leeg nqaij
• Hlwb pauv

Kev kuaj ntshav tuaj yeem ua kom paub txog cov tshuaj tsim los ntawm cov kab mob uas ua rau mob syphilis, qhov no suav nrog:

• Treponema pallidum agglutination kev faib ua feem (TPPA)
• Kev sim ntsuas kab mob vwm (VDRL) kev kuaj mob
• Cov tshuaj fluorescent treponemal antibody absorption (FTA-ABS)
• Kev kho ntshav maim sai reagin (RPR)

Nrog neurosyphilis, nws yog ib qho tseem ceeb kom kuaj cov pob txha caj qaum rau cov cim qhia mob syphilis.

Kev ntsuam xyuas los saib teeb meem nrog lub paj hlwb yuav suav nrog:

• Cerebral angiogram
• Lub taub hau CT scan
• Lumbar puncture (txha caj qaum) thiab cerebrospinal kua (CSF) kev tshawb xyuas
• MRI scan ntawm lub paj hlwb, paj hlwb paj hlwb, lossis leeg nrob qaum

Cov tshuaj tua kab mob penicillin yog siv los kho cov tshuaj neurosyphilis. Nws tuaj yeem muab raws ntau txoj kev:

• Txhaj rau hauv cov hlab ntshav ob peb zaug hauv ib hnub rau 10 mus rau 14 hnub.
• Ntawm qhov ncauj 4 zaug hauv ib hnub, ua ke nrog txhua hnub ntawm cov leeg, ob leeg noj 10 mus rau 14 hnub.

Koj yuav tsum tau kuaj ntshav ntxiv tom qab 3, 6, 12, 24, thiab 36 lub hlis kom paub tseeb tias tus mob tau ploj mus. Koj yuav tsum tau soj qab lumbar punctures rau CSF kev txheeb xyuas txhua 6 lub hlis. Yog tias koj mob HIV / AIDS lossis lwm yam mob, koj cov sijhawm rov qab mus tshuaj yuav txawv.

Neurosyphilis yog ib yam mob uas yuav txo tau txoj sia ntawm tus mob syphilis. Koj yuav ua tau zoo npaum li cas nyob ntawm seb mob neurosyphilis hnyav npaum li cas ua ntej kev kho mob. Lub hom phiaj ntawm kev kho mob yog txhawm rau tiv thaiv kom txhob mob ntxiv lawm. Ntau yam ntawm cov kev hloov pauv no tsis thim rov qab.

Cov tsos mob tuaj yeem ua rau qeeb qeeb.

Hu rau koj tus kws kho mob yog tias koj tau mob syphilis yav dhau los thiab tam sim no muaj cov cim qhia teeb meem ntawm lub paj hlwb.

Kev kuaj mob sai thiab kho tus mob syphilis qub yuav tiv thaiv neurosyphilis.

Syphilis - neurosyphilis

• Nruab nrab hauv lub paj hlwb thiab lub paj hlwb peripheral
• Qib-theem syphilis

Euerle BD. Cov leeg txha caj qaum txhaws thiab cerebrospinal kua tshuaj. Hauv: Roberts JR, Custalow CB, Thomsen TW, eds. Roberts thiab Hedges 'Cov Txheej Txheem Chaw Kho Mob hauv Xwm Ceev Kho Mob thiab Mob Zoo MobCov. 7 tus ed. Philadelphia, PA: Elsevier; 2019: chap 60.

Lub koom haum National of Neurological Disorders thiab Stroke lub vev xaib. Neurosyphilis. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis- Xov Xwm-Page. Hloov kho thaum Lub Peb Hlis 27, 2019. Nkag mus rau Lub Ob Hlis 19, 2021.

Radolf JD, Tramont EC, Salazar JC. Mob ntsws Syphilis (Treponema pallidum). Hauv: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, thiab Bennett's Cov Ntsiab Cai thiab Kev Coj Ua ntawm Kab Mob KisCov. 9le ed. Philadelphia, PA: Elsevier; 2020: cha 237.