Tus mob Nifaisrotic

Tus mob Nifaisrotic yog ib cov kev mob tshwm sim xws li muaj protein nyob hauv cov zis, cov ntshav muaj protein tsawg nyob hauv cov ntshav, cov ntshav muaj roj ntau ntau, cov roj triglyceride siab, muaj feem yuav ua rau muaj ntshav txhaws, thiab o.

Cov mob siab ntsws yog los ntawm kev puas tsuaj sib txawv uas ua rau lub raum puas tsuaj. Qhov kev puas tsuaj no ua rau kev tso cov protein ntau hauv cov zis.

Yam tshwm sim feem ntau ntawm cov menyuam yaus yog qhov kev hloov pauv me me. Membranous glomerulonephritis yog hom mob rau cov neeg laus. Hauv ob qho kab mob, lub glomeruli hauv ob lub raum puas ntsoog. Glomeruli yog cov qauv uas pab ua haujlwm lim thiab kua dej.

Tus mob no tseem tuaj yeem tshwm sim los ntawm:

• Mob Cancer
• Cov kab mob xws li mob ntshav qab zib, kab mob lupus erythematosus, ntau yam mob myeloma, thiab amyloidosis
• Kev mob caj ces tsis sib xws
• Kev txhaj tshuaj tiv thaiv kab mob
• Cov kab mob (xws li mob caj pas, mob rau daim siab, lossis mononucleosis)
• Siv qee yam tshuaj

Nws tuaj yeem tshwm sim lub raum tsis zoo xws li:

• Ua ke thiab segmental glomerulosclerosis
• Glomerulonephritis
• Mesangiocapillary glomerulonephritis

Tus mob Nifaisrotic tuaj yeem cuam tshuam txhua pawg hnub nyoog. Hauv cov menyuam yaus, nws yog tshwm sim feem ntau ntawm cov hnub nyoog 2 thiab 6. Qhov kev tsis zoo no tshwm sim ntau dua hauv cov txivneej ntau dua li poj niam.

O o (edema) yog tus tsos mob feem ntau. Tej zaum nws yuav tshwm sim:

• Hauv ntsej muag thiab ncig lub qhov muag (ntsej muag o)
• Hauv caj npab thiab txhais ceg, tshwj xeeb tshaj yog nyob hauv tus taw thiab pob taws
• Hauv plab tsam (thaj tsam mob plab)

Lwm cov tsos mob muaj xws li:

• Cov tawv nqaij ua pob los yog ua paug
• Foamy tsos ntawm cov zis
• Tsis qab los noj mov
• Qhov hnyav nce (tsis xav txog) los ntawm kev tuav dej
• Qaug dab peg

Tus kws kho mob yuav kuaj xyuas lub cev. Kuaj ntshav yuav kuaj xyuas seb lub raum ua haujlwm li cas. Lawv suav nrog:

• Kev kuaj ntshav albumin
• Kev kuaj ntshav cov ntshav, xws li cov teeb meem metabolic lossis vaj huam sib luag metabolic vaj huam sib luag
• Ntshav urea nitrogen (BUN)
• Creatinine - kuaj ntshav
• Creatinine tshem tawm - kuaj zis
• Mob Lub Hlaus

Cov rog yog feem ntau kuj muaj nyob hauv cov zis. Ntshav hauv cov ntshav thiab triglyceride qib yuav siab.

Yuav siv ib lub raum mus kuaj xyuas seb yog vim li cas tus mob thiaj li muaj mob.

Kev ntsuam xyuas los txiav txim rau ntau qhov laj thawj yuav suav nrog cov hauv qab no:

• Antinuclear tiv thaiv
• Cryoglobulins
• Sib txuam sib luag
• Kuaj ntshav qab zib kuaj
• Cov tshuaj tiv thaiv kab mob siab B thiab C
• Kuaj HIV
• Qhov zoo tshaj yuav Rheumatoid
• Ntshav protein electrophoresis (SPEP)
• Syphilis serology
• Zis protein electrophoresis (UPEP)

Tus kab mob no kuj tseem tuaj yeem pauv cov txiaj ntsig ntawm kev sim hauv qab no:

• Qib Vitamin D
• Ntshav hlau
• Tso quav tso zis

Lub hom phiaj ntawm kev kho mob yog los daws cov tsos mob, tiv thaiv kom tsis txhob muaj teeb meem, thiab ncua raum. Txhawm rau tswj cov mob nephrotic, kev cuam tshuam uas tau ua rau nws yuav tsum tau kho. Tej zaum koj yuav xav tau kev kho mob rau lub neej.

Cov kev kho mob yuav suav nrog ib qho hauv qab no:

• Ua kom cov ntshav siab nyob qis lossis qis dua 130/80 hli Hg kom ncua sijhawm rau lub raum. Angiotensin-converting enzyme (ACE) inhibitors lossis angiotensin receptor blockers (ARBs) yog cov tshuaj uas feem ntau siv. ACE inhibitors thiab ARBs kuj tseem tuaj yeem pab txo cov protein tsawg hauv cov zis.
• Corticosteroids thiab lwm yam tshuaj uas tawm tsam lossis ua kom lub cev tsis muaj zog.
• Kev kho cov roj (cholesterol) tsawg los txo cov teeb meem kev mob plawv thiab cov ntshav hlab ntaws - Kev noj zaub mov muaj roj tsawg, cov rog muaj roj tsawg feem ntau tsis txaus rau cov neeg muaj nephrotic syndrome. Cov tshuaj los txo cov roj thiab triglycerides (feem ntau statins) kuj yuav xav tau.
• Kev noj zaub mov kom muaj ntsev ntau yuav pab kom o ntawm tes thiab ceg. Tshuaj ntsiav dej (tshuaj tua kab mob) kuj tseem yuav pab tau qhov teeb meem no.
• Kev noj zaub mov muaj protein tsawg yuav pab tau. Koj tus kws kho mob yuav hais tias kom noj cov protein kom txaus (noj 1 gram ntawm cov protein ib phaus ntawm lub cev hnyav hauv ib hnub).
• Noj tshuaj vitamin D pab ntxiv yog tias tus mob nephrotic siv tau ntev thiab tsis teb kho mob.
• Kev noj cov ntshav tshuaj dua los kho lossis tiv thaiv cov ntshav txhaws.

Qhov tshwm sim nws txawv. Muaj qee tus neeg rov zoo los ntawm tus mob. Lwm tus mob raum ntev lub raum thiab xav lim ntshav thiab thaum kawg hloov raum.

Cov teeb meem kev noj qab haus huv uas tuaj yeem yog los ntawm tus mob nephrotic muaj xws li:

• Mob raum tsis ua hauj lwm
• Ua kom nruj ntawm cov hlab ntsha thiab cov kab mob hauv lub plawv
• Mob raum
• Kev ua kua ntau dhau, lub plawv nres, ua kua hauv lub ntsws
• Cov kab mob sib kis, nrog rau kev mob ntsws
• Khoom noj khoom haus tsis muaj zog
• Hlab ntsha leeg ntshav hlab ntsha

Hu rau koj tus kws khomob yog:

• Koj lossis koj tus menyuam muaj tsos mob ntawm tus mob nephrotic, suav nrog rau ntsej muag, plab, lossis caj npab thiab ceg, lossis daim tawv nqaij ua paug
• Koj lossis koj tus menyuam raug kho rau tus mob nephrotic syndrome, tab sis cov tsos mob tsis zoo
• Cov tsos mob tshiab tshwm sim, suav nrog kev hnoos, tso zis tawm kom tsawg, tsis xis nyob nrog tso zis, kub taub hau, mob taub hau heev

Mus rau chav kho mob ceev lossis hu rau tus npawb xov tooj xwm ceev hauv nroog (xws li 911) yog tias koj muaj mob chua leeg.

Kho cov mob uas tuaj yeem ua rau tus mob nephrotic yuav pab tiv thaiv tus mob.

Nephrosis

• Raum anatomy

Erkan E. Nephrotic syndrome. Hauv: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Phau Ntawv ntawm PediatricsCov. 21st ed. Philadelphia, PA: Elsevier; 2020: chap 545.

Saha MK, Pendergraft WF, Jennette JC, Falk RJ. Thawj tus kab mob glomerular. Hauv: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner thiab Rector's RaumCov. 11th ed. Philadelphia, PA: Elsevier; 2020: chap 31.