Eosinophilic fasciitis

Eosinophilic fasciitis (EF) yog ib qho kev mob tshwm sim hauv cov nqaij uas nyob hauv qab daim tawv nqaij thiab dhau cov leeg nqaij, hu ua fascia, dhau mus o tuaj, kub thiab tuab. Daim tawv nqaij ntawm caj npab, ceg, caj dab, plab thiab taw tuaj yeem nrawm nrawm. Tus mob no muaj tsawg heev.

EF tuaj yeem saib zoo ib yam li scleroderma, tab sis tsis cuam tshuam. Tsis zoo li scleroderma, hauv EF, cov ntiv tes tsis koom nrog.

Qhov ua rau EF tseem tsis tau paub. Cov teeb meem tsis tshua muaj tshwm sim tau tshwm sim tom qab noj L-tryptophan tshuaj ntxiv. Hauv cov neeg muaj tus mob no, cov qe ntshav dawb, hu ua eosinophils, ua kom cov leeg thiab cov ntaub so ntswg. Eosinophils txuas nrog rau kev ua xua. Tus mob no tshwm sim ntau rau cov neeg hnub nyoog 30 txog 60 xyoo.

Cov tsos mob tuaj yeem suav nrog:

• Kev sib tw thiab o ntawm daim tawv nqaij ntawm caj npab, ceg, lossis qee zaum cov pob qij txha (feem ntau ntawm ob sab ntawm lub cev)
• Mob caj dab
• Tus mob carpal
• Mob leeg
• Thickened tawv uas zoo li puckered

Kev ntsuam xyuas uas yuav ua tau muaj xws li:

• CBC nrog qhov sib txawv
• Gamma globulins (ib hom protein tiv thaiv kab mob)
• Erythrocyte tus nqi txo qis (ESR)
• MRI
• Nqaij xyoob
• Daim tawv nqaij txiav (cov nqaij coj mus kuaj yuav tsum suav nrog cov nqaij mos ntawm cov fascia)

Corticosteroids thiab lwm yam tshuaj tiv thaiv kab mob hauv lub cev tau siv los daws cov tsos mob. Cov tshuaj no zoo dua qub thaum pib ua haujlwm ntxov. Cov tshuaj nonsteroidal anti-inflammatory (NSAIDs) kuj tseem yuav pab txo cov tsos mob.

Feem ntau, cov mob yuav ploj mus li ntawm 1 txog 3 xyoos. Txawm li cas los xij, cov tsos mob yuav mob ntev dua lossis rov qab los.

Mob pob txaws yog qhov tsis txaus ntseeg ntawm EF. Qee tus neeg yuav muaj feem ua mob ntshav hnyav lossis mob ntshav qog, xws li mob ntshav lossis ntshav liab lossis ntshav ntws. Qhov zeem muag yuav tshwm sim hnyav dua yog tias cov kabmob ntshav tshwm sim.

Hu koj tus kws kho mob yog tias koj muaj cov tsos mob ntawm qhov tsis zoo no.

Tsis muaj kev paub txog kev tiv thaiv.

Shulman syndrome

• Sab nqaij tawv ntawm xub ntiag

Aronson JK. Tryptophan. Hauv: Aronson JK, ed. Meyler Qhov tshwm sim los ntawm Cov TshuajCov. 16th ed. Waltham, MA: Elsevier B.V .; 2016: 220-221.

James WD, Elston DM, Kho JR, Rosenbach MA, Neuhaus IM. Kev tiv thaiv cov kab mob nqaij. Hauv: James WD, Elston DM, Kho JR, Rosenbach MA, Neuhaus IM, eds. Andrews 'Cov Kab Mob Ntawm Cov tawv nqaij: Soj Ntsuam Kev Siv Tshuaj LomCov. 13th ed. Philadelphia, PA: Elsevier; 2020: chap 8.

Lee LA, Werth VP. Daim tawv nqaij thiab mob rheumatic. Hauv: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley thiab Firestein Cov Ntawv Phau Ntawv ntawm RheumatologyCov. 10 tus ed. Philadelphia, PA: Elsevier; 2017: chaaj 43.

Pinal-Fernandez I, Selva-O 'Callaghan A, Grau JM. Kev kuaj mob thiab kev faib tawm ntawm eosinophilic fasciitis. Autoimmun RevCov. Xyoo 2014; 13 (4-5): 379-382. PMID: 24424187 www.ncbi.nlm.nih.gov/pubmed/24424187.

Koom Haum Hauv Lub Tebchaws rau Cov Tsis Txaus. Eosinophilic fasciitis. rarediseases.org/rare-diseases/eosinophilic-fasciitis/. Hloov tshiab 2016. Nkag mus rau Lub Peb Hlis 6, 2017.