Pheochromocytoma

Pheochromocytoma yog cov qog ua haujlwm rau cov qog ua qog ua ntshav. Nws ua rau tso tawm ntau dhau ntawm epinephrine thiab norepinephrine, cov tshuaj hormones uas tswj lub plawv dhia, cov metabolism, thiab ntshav siab.

Pheochromocytoma tej zaum yuav tshwm sim li ib leeg xwb lossis ntau tshaj ib qhov kev loj hlob tuaj. Feem ntau nws loj hlob hauv nruab nrab (medulla) ntawm ib lossis ob lub qog adrenal. Lub qog adrenal yog ob lub qog-ob daim qog. Ib lub qog nyob rau sab saum toj ntawm txhua lub raum. Muaj qee zaus, pheochromocytoma tshwm sim sab nraum lub qog adrenal. Thaum nws ua, nws feem ntau yog lwm qhov chaw hauv plab.

Cov pheochromocytomas tsawg tsawg yog cov qog nqaij hlav.

Cov qog yuav tshwm sim thaum muaj hnub nyoog li cas, tab sis feem ntau lawv txij li thaum ntxov mus txog thaum laus.

Hauv qee qhov xwm txheej, cov xwm txheej yuav pom ntawm cov neeg hauv tsev neeg (mob muaj keeb).

Cov neeg feem ntau uas muaj cov hlav no tau tawm tsam ntawm cov kev mob tshwm sim, uas tshwm sim thaum lub qog tawm cov qog. Kev tawm tsam feem ntau kav los ntawm ob peb feeb mus rau teev. Txheej cov tsos mob muaj xws li:

• Mob taub Hau
• Lub plawv palpitations
• Tawm hws
• Ntshav siab

Raws li cov qog loj tuaj, cov kev tawm tsam feem ntau ua rau ntau zaus, ntev, thiab mob hnyav.

Lwm cov tsos mob uas yuav tshwm sim suav nrog:

• Mob plab los yog mob hauv siab
• Kev npau taws, puas ntsoog
• Pallor
• Lub cev yuag
• Xeev siab thiab ntuav
• Ua tsis taus pa
• Qaug dab peg
• Teeb meem pw tsaug zog

Tus kws kho mob yuav kuaj xyuas lub cev. Luag yuav nug koj txog koj li kev mob thiab kev mob tshwm sim.

Kev ntsuam xyuas ua muaj xws li:

• Mob plab hauv TV
• Adrenal kuaj mob
• Catecholamines ntshav kuaj (ntshav tshuajateate)
• Kev kuaj qabzib
• Kev ntsuas cov ntshav ntawm Metanephrine (ntshiab metanephrine)
• Kev ntsuam xyuas cov duab hu ua MIBG scintiscan
• MRI ntawm lub plab mog
• Zis catecholamines
• Zis metanephrines
• TSIAJ scan ntawm lub plab mog

Kev kho mob cuam tshuam nrog tshem tawm cov qog nrog phais. Nws yog ib qho tseem ceeb los tswj koj cov ntshav siab thiab cov mem tes nrog qee yam tshuaj ua ntej kev phais mob. Tej zaum koj yuav xav tau nyob hauv tsev kho mob thiab tau txais koj cov phiajcim tseem ceeb los saib xyuas lub sijhawm phais mob. Tom qab phais tas, koj cov cim tseem ceeb yuav raug tshuaj xyuas nyob hauv chav saib xyuas mob hnyav.

Thaum cov hlav tawm tsis tuaj yeem raug phais, koj yuav tsum tau noj tshuaj los tswj hwm nws. Kev sib xyaw ua ke ntawm cov tshuaj feem ntau xav tau los tswj kev cuam tshuam ntawm cov tshuaj hormones ntxiv. Kev siv hluav taws xob thiab kev siv tshuaj kho mob tsis tau zoo los kho cov qog ntshav.

Cov neeg feem coob uas muaj hlav hlav tsis ua haujlwm tshem tawm nrog kev phais mob yog tseem muaj sia nyob tom qab 5 xyoos. Cov qog yuav rov los nyob hauv qee tus neeg. Qib ntawm cov tshuaj hormones norepinephrine thiab epinephrine rov zoo li qub tom qab kev phais mob.

Txuas ntxiv ntshav siab tuaj yeem tshwm sim tom qab kev phais mob. Cov kev kho mob ib txwm tuaj yeem tswj hwm tus mob ntshav siab.

Cov neeg uas tau txais kev kho tus mob pheochromocytoma zoo yuav tsum tau kuaj ib zaug dhau ib zaug kom paub tseeb tias cov qog tsis rov qab los. Cov neeg nyob ze tsev neeg kuj tseem tuaj yeem tau txais txiaj ntsig los ntawm kev sim, vim tias qee kis muaj peev xwm raug cai.

Hu rau koj tus kws khomob yog koj:

• Muaj cov tsos mob ntawm pheochromocytoma, xws li mob taub hau, tawm hws, thiab tawm hauv lub plab
• Muaj tus kab mob pheochromocytoma yav dhau los thiab koj cov tsos mob rov qab

Chromaffin hlav; Paraganglionoma

• Cov qog endocrine
• Adrenal metastases - CT scan
• Cov tshuaj qog Adrenal - CT
• Adrenal caj pas hormone tso pa tawm

Lub koom haum Cancer National website. Kev kho mob Pheochromocytoma thiab paraganglioma (PDQ) - cov kws kho mob kom zoo ntxiv. Cancer.gov. www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-nyuj-pdq#link/_38_toc. Hloov kho Cuaj hlis 23, 2020. Nkag mus siv Lub Kaum Hli 14, 2020.

Pacak K, Timmers HJLM, Eisenhofer G. Pheochromocytoma. Hauv: Jameson JL, De Groot LJ, de Kretser DM, li al, eds. Endocrinology: Cov Neeg Loj thiab Pediatric. 7 tus ed. Philadelphia, PA: Elsevier Saunders; 2016: cha 110.

Brigode WM, Miraflor EJ, Palmer BJA. Kev tswj hwm ntawm pheochromocytoma. Hauv: Cameron AM, Cameron JL, eds. Kev Kho Mob Tam Sim No. 13th ed. Philadelphia, PA: Elsevier; 2020: 750-756.