Acanthocytes Yog Dab Tsi?

Zoo Siab

• Hais txog acanthocytes: Lawv los qhov twg los thiab qhov chaw uas lawv pom
• Acanthocytes thiab echinocytes
• Yuav kuaj li cas thiaj paub tus mob acanthocytosis?
• Cov mob thiab cov tsos mob ntawm acanthocytosis
• Tshuaj tua kab mob acanthocytosis
• Neuroacanthocytosis
• Kev Cuam Tshuam Abetalipoproteinemia
• Txais acanthocytosis
• Nqa Nyiaj

Acanthocytes yog cov qe ntshav liab tsis zoo nrog cov kab mob sib txawv ntawm qhov ntev thiab qhov dav tsis txaus ntseeg ntawm lub ntsej muag ntawm tes. Lub npe los ntawm Greek lo lus "acantha" (uas txhais tau tias "pos") thiab "kytos" (uas txhais tau tias "cell").

Cov hlwb txawv txawv no cuam tshuam nrog ob qho tib si los ntawm cov kab mob thiab kev kis tau los. Tab sis feem ntau cov neeg laus muaj feem pua ​​me me ntawm cov acanthocytes hauv lawv cov ntshav.

Hauv tsab xov xwm no, peb yuav piav txog cov ntsiab lus hais txog acanthocytes, uas lawv txawv ntawm echinocytes, thiab cov xwm txheej hauv qab uas cuam tshuam nrog lawv.

Hais txog acanthocytes: Lawv los qhov twg los thiab qhov chaw uas lawv pom

Acanthocytes yog xav los ntawm kev hloov pauv hauv cov protein thiab lipids ntawm cov cell liab. Raws nraim li cas thiab vim li cas cov ntsia hlau loj tsis yog to taub tag nrho.

Acanthocytes pom nyob hauv cov neeg muaj qhov xwm txheej li no:

• mob rau daim siab hnyav
• tsawg kab mob neural, xws li chorea-acanthocytosis thiab McLeod syndrome
• khoom noj khoom haus tsis muaj zog
• hypothyroidism
• Abetalipoproteinemia (mob uas tsis tshua muaj tus kab mob uas tsis muaj peev xwm nqus tau qee cov rog rog)
• tom qab tshem tus po (splenectomy)
• anorexia nervosa

Qee cov tshuaj, xws li statins lossis misoprostol (Cytotec) muaj feem xyuam nrog acanthocytes.

Acanthocytes tseem pom nyob hauv cov zis ntawm cov neeg mob ntshav qab zib uas muaj tus mob glomerulonephritis, yog ib hom mob raum tsis zoo.

Vim tias lawv cov duab, nws tau xav tias acanthocytes tuaj yeem ua rau pob thiab puas rau hauv tus po, ua rau hemolytic tsis txaus.

Nov yog piv txwv txog tsib acanthocytes ntawm cov ntshav liab.

Getty Dluab

Acanthocytes thiab echinocytes

Qhov acanthocyte zoo ib yam li lwm qhov ntshav liab uas tsis txaus ntseeg hu ua echinocyte. Echinocytes tseem muaj cov ntsia hlau loj ntawm lub ntsej muag ntawm tes, txawm tias lawv tau me dua, zoo li niaj zaus, thiab muaj qhov sib luag ntawm lub ntsej muag ntawm tes.

Lub npe echinocyte los ntawm Greek lo lus "echinos" (uas txhais tau tias "urchin") thiab "kytos" (uas txhais tau tias "cell").

Echinocytes, tseem hu ua burr cell, cuam tshuam nrog kev mob raum, mob kab mob siab, thiab ua tsis tau cov leeg ntshav pimuvate kinase.

Yuav kuaj li cas thiaj paub tus mob acanthocytosis?

Acanthocytosis yog hais txog qhov muaj qhov txawv txav ntawm acanthocytes hauv cov ntshav. Cov ntshav tsis muaj ntshav liab no muaj peev xwm pom nyob ntawm saib cov ntshav muaj pes tsawg leeg.

Qhov no hais txog kev tso koj cov ntshav ntawm lub khob tsom, kom nws staining, thiab ntsia hauv lub tshuab tsom. Nws tseem ceeb heev uas yuav tau siv cov ntshav tshiab; txwv tsis pub, acanthocytes thiab echinocytes yuav zoo ib yam nkaus.

Txheeb xyuas qee yam mob uas cuam tshuam nrog acanthocytosis, koj tus kws kho mob yuav coj tag nrho cov keeb kwm kho mob thiab nug txog koj cov tsos mob. Lawv tseem yuav nug txog qhov ua tau los ntawm kev muaj cai thiab kuaj ib ce.

Ntxiv nrog rau kev tua ntshav, tus kws kho mob yuav xaj ib qho ntshav tiav thiab lwm yam kev kuaj mob. Yog tias lawv xav tias kev koom nrog neural, lawv tuaj yeem xaj kom lub hlwb MRI kuaj xyuas.

Cov mob thiab cov tsos mob ntawm acanthocytosis

Qee hom mob acanthocytosis yog cov qub txeeg qub teg, hos lwm cov neeg kis ntxiv.

Tshuaj tua kab mob acanthocytosis

Cov mob muaj keeb tshwj xeeb tau los ntawm kev hloov cov noob caj noob ces uas muaj raws noob caj noob ces. Tus gene yuav tau txais los ntawm niam thiab txiv lossis ob niam txiv tib si.

Ntawm no yog qee yam tshwj xeeb rau kev mob:

Neuroacanthocytosis

Neuroacanthocytosis yog hais txog acanthocytosis cuam tshuam nrog cov teeb meem hlwb. Cov no muaj tsawg kawg, nrog kwv yees li ntawm ib mus rau tsib kis rau 1,000,000 pejxeem.

Cov no yog ib yam kev hloov zuj zus, suav nrog:

• Chorea-acanthocytosis. Qhov no feem ntau tshwm sim hauv koj li 20s.
• McLeod mob. Qhov no tuaj yeem tshwm sim thaum muaj hnub nyoog 25 txog 60 xyoo.
• Cov kab mob Huntington's zoo li 2 (HDL2). Qhov no feem ntau tshwm sim thaum tseem hluas.
• Pantothenate kinase-txuam neurodegeneration (PKAN). Qhov no feem ntau pom tshwm hauv cov menyuam yaus hnub nyoog qis dua 10 thiab nce qib sai sai.

Cov tsos mob thiab tus mob kuj txawv ntawm ib tug neeg. Feem ntau, cov tsos mob suav nrog:

• kev ua tej yam txawv txav
• peev xwm poob
• qaug dab peg
• dystonia

Qee tus neeg kuj tseem yuav muaj cov kev puas siab puas ntsws.

Tseem tsis tau muaj kev kho tau tus mob neuroacanthocytosis. Tab sis cov tsos mob tuaj yeem kho tau. Cov chaw kuaj mob thiab txhawb nqa cov koom haum rau neuroacanthocytosis yog muaj.

Kev Cuam Tshuam Abetalipoproteinemia

Cov kab mob Abetalipoproteinemia, tseem hu ua Bassen-Kornzweig syndrome, tshwm sim los ntawm kev muab cov noob caj noob ib yam los ntawm ob leeg niam txiv. Nws suav nrog kev tsis tuaj yeem nqus cov zaub mov muaj rog, cov roj cholesterol, thiab cov vitamins-fat-soluble vitamins, xws li cov vitamin E.

Abetalipoproteinemia feem ntau tshwm sim thaum tseem yau, thiab tuaj yeem kho nrog cov vitamins thiab lwm yam tshuaj ntxiv.

Cov tsos mob tuaj yeem suav nrog:

• tsis ua haujlwm li menyuam yaus
• cov leeg nyuaj, xws li kev tswj cov leeg tsis zoo
• qeeb kev txawj ntse
• teeb meem plab zom mov, xws li zawv plab thiab tso quav ua pa tsw phem
• teeb meem qhov muag tau zuj zus zuj zus

Txais acanthocytosis

Ntau yam mob hauv tsev kho mob tau cuam tshuam nrog acanthocytosis. Lub tshuab kev koom tes tsis yog ib txwm to taub. Ntawm no yog qee qhov ntawm cov xwm txheej:

• Mob rau daim siab hnyav. Acanthocytosis yog xav tias yog los ntawm kev tsis txaus ntawm cov roj cholesterol thiab phospholipid ntawm cov qe ntshav ntawm lub hlwb. Nws tuaj yeem hloov rov qab nrog lub siab hloov chaw.
• Spleen tshem tawm. Splenectomy feem ntau cuam tshuam nrog acanthocytosis.
• Mob tsis nco qab. Acanthocytosis tshwm sim rau qee cov neeg muaj mob tsis nco qab. Nws tuaj yeem rov qab nrog kev kho mob rau tus mob anorexia.
• Kev Hypothyroidism. Kwv yees li ntawm 20 feem pua ​​ntawm cov neeg muaj tus mob hypothyroidism pib mob acanthocytosis. Acanthocytosis tseem tseem ua rau muaj kev mob siab ntsws hypothyroidism (myxedema).
• Myelodysplasia. Qee cov neeg uas muaj hom mob ntshav hauv ntshav pib mob acanthocytosis.
• Kab mob ntsws. Qee cov neeg uas muaj tus kab mob no cov ntshav yuav muaj tus mob acanthocytosis.

Lwm yam mob uas yuav cuam tshuam nrog acanthocytosis yog cystic fibrosis, tus mob celiac, thiab kev noj haus tsis zoo.

Nqa Nyiaj

Acanthocytes yog cov qe ntshav liab tsis zoo uas muaj cov roj ntsha tsis xwm yeem hauv lub ntsej muag ntawm tes. Lawv tau cuam tshuam nrog cov kev muaj mob uas tau muaj tsawg tsawg nrog rau kev ua kom muaj ntau yam.

Tus kws kho mob tuaj yeem ua qhov kev kuaj mob raws li cov tsos mob thiab mob ntxig cov ntshav pleev. Qee hom kev mob acanthocytosis muaj kev vam meej thiab kho tsis tau. Txais acanthocytosis feem ntau tuaj yeem kho thaum kho qhov mob hauv qab.