Nkag Siab Thib Ob-Txhim Kho Ntau Tus Kab Mob Sclerosis

Zoo Siab

• SPMS yog dab tsi?
• Yuav ua li cas cov relapsing-remitting MS dhau los ua SPMS
• Kev kuaj mob SPMS
• Kho SPMS
• Cov chaw kuaj mob
• Kev vam meej
• Modifiers
• Lub neej tos
• Outlook rau SPMS

SPMS yog dab tsi?

Secondary-progressive ntau yam sclerosis (SPMS) yog ib hom kev mob ntau yam sclerosis. Nws tau pom tias theem tom qab yog rov qab rov huam dua MS (RRMS).

Nrog rau SPMS, tsis muaj ib qho cim ntawm qhov kev zam txim ntxiv lawm. Qhov no txhais tau hais tias tus mob hnyav zuj zus txawm tias yuav kho li cas los xij. Txawm li cas los xij, kev kho mob tseem raug pom zoo nyob rau qee lub sijhawm los pab txo kev tawm tsam thiab cia siab qeeb qhov kev vam meej ntawm kev tsis taus.

Theem no yog tshwm sim. Qhov tseeb, feem ntau cov neeg nrog MS yuav tsim kho SPMS ntawm qee kis yog tias tsis kho tshuaj kho kab mob (DMT) zoo. Paub txog cov cim ntawm SPMS tuaj yeem pab koj paub ntxov. Thaum koj pib kho sai, koj tus kws kho mob yuav pab tau koj txo cov tsos mob tshiab ntau zuj zus thiab mob koj tus mob.

Yuav ua li cas cov relapsing-remitting MS dhau los ua SPMS

MS yog tus kab mob autoimmune mob uas los ntawm ntau hom thiab cuam tshuam rau tib neeg sib txawv. Raws li Johns Hopkins Tshuaj Kho Mob, kwv yees li 90 feem pua ​​ntawm cov neeg nrog MS pib kuaj mob RRMS.

Hauv theem RRMS, thawj cov tsos mob tshwm sim muaj xws li:

• loog lossis tingling
• kev tswj tsis tau (teeb meem tswj zais zis)
• kev hloov pauv ntawm lub zeem muag
• taug kev nyuaj
• qaug zog ntau dhau

Cov tsos mob RRMS tuaj yeem mus thiab mus. Qee tus neeg yuav tsis muaj cov tsos mob rau ntau lub lis piam lossis ntau lub hlis, qhov tshwm sim hu ua kev zam txim. MS cov tsos mob tuaj yeem rov qab los, ib yam nkaus, txawm tias qhov no hu ua flare-up. Tib neeg kuj tuaj yeem tsim cov tsos mob tshiab. Qhov no hu ua kev tawm tsam, lossis rov huam mob.

Ib qho kev rov huam mob dua li ob peb hnub mus rau ntau lub lis piam. Cov tsos mob tuaj yeem hloov zuj zus mus zuj zus thaum pib thiab tom qab ntawd hloov zuj zus mus ib ntus yam tsis tau kho lossis ntxov nrog cov tshuaj steroids. RRMS yog yam ua tsis tau.

Ntawm qee kis, ntau tus neeg uas RRMS tsis muaj lub sijhawm ntawm kev tshem tawm lossis cia li rov huam mob dua. Hloov chaw, lawv cov tsos mob MS tseem mob zuj zus thiab tsis muaj hnub so.

Txuas ntxiv, cov tsos mob phem zuj zus tuaj qhia tias RRMS tau nce mus rau SPMS. Qhov no feem ntau tshwm sim 10 rau 15 xyoos tom qab thawj cov tsos mob MS. Txawm li cas los xij, SPMS tuaj yeem ncua sijhawm lossis txawm tias muaj kev tiv thaiv yog tias pib siv MS DMTs thaum ntxov nyob rau hauv chav kis mob.

Cov tsos mob zoo sib xws muaj nyob hauv txhua hom MS. Tab sis SPMS cov tsos mob tshwm sim thiab tsis txhim kho thaum lub sijhawm.

Thaum nyuam qhuav pib RRMS, cov tsos mob tshwm sim tau pom, tab sis lawv tsis tas yuav cuam tshuam nrog cov haujlwm txhua hnub. Thaum MS hloov zuj zus mus rau theem ob-theem zuj zus, cov tsos mob ua rau nyuaj.

Kev kuaj mob SPMS

SPMS muaj kev txhim kho raws li cov neuronal poob thiab atrophy. Yog tias koj pom koj cov tsos mob hnyav zuj zus yam tsis muaj kev kho dua los yog rov tshwm sim dua, kev thaij MRI yuav pab tau rau kev kuaj mob.

MRI scans tuaj yeem qhia txog qib kev tuag ntawm tes thiab lub paj hlwb atrophy. Ib qho MRI yuav qhia qhov sib txawv ntau ntxiv thaum muaj kev tawm tsam vim tias to ntawm cov hlab ntsha thaum lub sij hawm nres yuav ua rau muaj kev cuam tshuam ntau dua ntawm cov gadolinium zas uas siv hauv MRI scans.

Kho SPMS

SPMS tau cim los ntawm qhov tsis muaj kev rov huam mob tuaj, tab sis nws tseem muaj peev xwm ua rau muaj mob ntawm cov tsos mob, tseem hu ua flare-up. Flare-ups feem ntau ua rau kub thiab thaum lub sijhawm muaj kev ntxhov siab.

Tam sim no, muaj 14 DMTs siv rau cov ntawv xa tawm ntawm MS, suav nrog SPMS uas txuas ntxiv mus rov huam mob. Yog tias koj tau noj ib qho ntawm cov tshuaj no los kho RRMS, koj tus kws kho mob tej zaum yuav muaj koj nyob rau ntawd kom txog thaum nws tso tseg tswj kev ua mob.

Lwm hom kev kho mob tuaj yeem pab txhim kho cov tsos mob thiab lub neej zoo. Cov no suav nrog:

• kev pab kho lub cev
• kev kho kom lub cev
• kev tawm dag zog ib txwm muaj
• kev nkag ua kom txawj ntse

Cov chaw kuaj mob

Cov chaw kho mob sim cov hom tshuaj tshiab thiab kev kho mob rau cov neeg tuaj yeem pab txhawm rau txhim kho kev kho mob rau SPMS. Tus txheej txheem no ua rau cov kws tshawb nrhiav pom meej meej tias dab tsi ua tau zoo thiab nyab xeeb.

Cov neeg ua haujlwm pab dawb rau hauv kev sim kho mob kuj yuav yog thawj cov tau txais cov kev kho mob tshiab, tab sis qee qhov kev pheej hmoo yog koom nrog. Cov kev kho mob yuav pab tsis tau SPMS, thiab hauv qee kis, lawv tuaj yeem muaj kev phiv loj heev.

Qhov tseem ceeb tshaj plaws, kev ceev faj yuav tsum nyob rau hauv chaw ceev cov neeg ua haujlwm pab dawb, nrog rau kev tiv thaiv lawv cov ntaub ntawv ntiag tug.

Cov neeg koom nrog kev sim kho mob feem ntau yuav tsum tau ua raws li qee cov lus qhia. Thaum txiav txim siab txiav txim siab koom nrog, nws yog ib qho tseem ceeb yuav tsum nug cov lus nug xws li lub sijhawm mus sib hais ntev li cas, cov kev mob tshwm sim tuaj yeem suav nrog, thiab vim li cas cov kws tshawb nrhiav xav tias nws yuav pab tau.

Lub National Ntau Yam Sclerosis Society lub vev xaib teev cov kev sim hauv tsev kawm ntawv hauv Tebchaws Meskas, txawm hais tias COVID-19 kev muaj thoob qhov yuav ua rau kev kawm qeeb.

Cov chaw kho mob sim tam sim no tau teev tseg rau kev nrhiav neeg ua haujlwm suav nrog ib qho rau simvastatin, uas tej zaum yuav ua rau qeeb qeeb ntawm SPMS, ntxiv rau kev tshawb fawb seb puas muaj ntau txoj kev kho tuaj yeem pab tib neeg nrog MS tswj kev mob.

Lwm qhov kev txiav txim siab txhawm rau sim seb puas muaj lipoic acid tuaj yeem pab cov tib neeg muaj kev nce qib MS nyob txawb thiab tiv thaiv lub hlwb.

Thiab kev sim tshuaj mob tau npaj tau tiav tom qab xyoo NurOwn cell no. Nws lub hom phiaj yog txhawm rau ntsuas kev nyab xeeb thiab ua tau ntawm kev kho mob qia neeg hauv cov neeg uas muaj MS.

Kev vam meej

Kev vam meej yog hais txog cov tsos mob uas tshwm sim los tsis zoo raws sijhawm. Ntawm qee kis, SPMS tuaj yeem piav tau tias yog "tsis muaj kev nce qib," txhais tau tias nws tsis zoo li qhov cuam tshuam loj dua.

Kev nce qib sib txawv nyob ntawm cov neeg SPMS. Hauv lub sijhawm, qee tus yuav tsum siv lub laub siv log, tab sis ntau tus neeg tseem muaj peev xwm taug kev, muaj peev xwm siv tus pas nrig lossis cov neeg mus kev.

Modifiers

Modifiers yog cov lus uas qhia seb koj SPMS ua haujlwm tsis tau nyob lossis tsis nyob hauv.Qhov no pab qhia cov lus sib tham nrog koj tus kws kho mob txog kev kho tau thiab qhov koj tuaj yeem xav tias yuav ua mus tom ntej.

Piv txwv, nyob rau hauv SPMS uas tseem ua haujlwm, koj yuav tsum tham txog cov kev kho tshiab. Hauv kev tsis sib thooj, nrog kev qoj ib ce, koj thiab koj tus kws kho mob yuav sib tham txog kev siv kho kom rov zoo thiab txoj hauv kev los tswj koj cov tsos mob nrog tej zaum DMT uas tsis muaj kev pheej hmoo tsawg.

Lub neej tos

Qhov nruab nrab lub neej nyob rau cov neeg nrog MS nyhav txog li 7 xyoo luv dua li cov pej xeem. Nws tseem tsis tau meej vim li cas.

Sib nrug los ntawm cov neeg mob hnyav MS, uas muaj tsawg tsawg, qhov tseem ceeb ua rau muaj lwm yam mob uas tseem cuam tshuam rau tib neeg, xws li mob qog noj ntshav thiab mob plawv thiab mob ntsws.

Qhov tseem ceeb, lub neej muaj kev cia siab rau cov neeg nrog MS tau nce ntau xyoo hauv xyoo tsis ntev los no.

Outlook rau SPMS

Nws yog ib qho tseem ceeb uas yuav tau siv los kho MS txhawm rau tswj hwm cov tsos mob thiab txo qhov ua tsis taus kom tsawg. Tshawb nrhiav thiab kho RRMS thaum ntxov yuav pab tiv thaiv qhov pib ntawm SPMS, tab sis tseem tsis muaj txoj kev kho tau.

Txawm hais tias tus mob yuav vam meej, nws yog ib qho tseem ceeb los kho SPMS kom ntxov li ntxov tau. Tsis muaj tshuaj kho tau, tab sis MS tsis tuag taus, thiab kev kho mob tuaj yeem txhim kho lub neej kom zoo. Yog tias koj muaj RRMS thiab tsis pom cov kev mob tshwm sim hnyav, nws yog lub sijhawm los tham nrog koj tus kws kho mob.