Ribavirin: tshuaj rau tus mob muaj kab mob siab C

Zoo Siab

• Dab tsi yog nws rau
• Yuav noj li cas
• Muaj kev phiv ntau
• Leej twg yuav tsum tsis txhob coj

Ribavirin yog ib yam khoom uas, thaum cuam tshuam nrog lwm cov kev kho tshwj xeeb, xws li alpha interferon, yog qhia rau kev kho kab mob siab C.

Cov tshuaj no tsuas yog siv tau yog tias tus kws kho mob pom zoo thiab tuaj yeem yuav tau tsuas yog thaum tso tawm tshuaj.

Dab tsi yog nws rau

Ribavirin yog qhia rau kev kho mob siab hom hepatitis C hauv cov neeg laus thiab menyuam yaus hnub nyoog 3 xyoos, ua ke nrog lwm cov tshuaj rau tus kabmob, thiab yuav tsum tsis txhob siv ib leeg.

Kawm paub yuav teev cov tsos mob li cas ntawm tus kab mob siab C.

Yuav noj li cas

Cov koob tshuaj pom zoo sib txawv raws li lub hnub nyoog, tus neeg qhov hnyav thiab cov tshuaj siv ua ke nrog ribavirin. Yog li, lub koob tshuaj yuav tsum tau ib txwm coj los ntawm tus kws kho mob hepatologist.

Thaum tsis muaj qhov kev pom zoo tshwj xeeb, cov lus qhia dav dav qhia:

• Cov laus muaj hnub nyoog qis dua 75 kg: ib koob tshuaj txhua hnub ntawm 1000 mg (5 tsiav tshuaj 200 mg) ib hnub, muab faib ua 2 koob tshuaj;
• Cov laus tshaj 75 kg: ib koob tshuaj 1200 mg (6 tsiav tshuaj 200 mg) ib hnub, muab faib ua 2 koob tshuaj.

Hauv kev siv rau menyuam yaus, lub koob tshuaj yuav tsum nco ntsoov xam los ntawm tus kws kho menyuam yaus, thiab qhov kev pom zoo nruab nrab txhua hnub yog 10 mg / kg lub cev qhov hnyav.

Muaj kev phiv ntau

Qee qhov kev mob tshwm sim feem ntau uas yuav tshwm sim thaum kho mob ribavirin yog kuaj ntshav liab, tsis nco qab hau, muaj kev nyuaj siab, pw tsis tsaug zog, mob taub hau, kiv taub hau, qaug zog poob siab, ua pa nyuaj, hnoos, raws plab, xeev siab, mob plab, plaub hau, dermatitis, khaus, qhuav tawv nqaij, leeg thiab mob pob qij txha, kub taub hau, ua daus no, mob, nkees, ua tshwm sim ntawm qhov chaw txhaj tshuaj thiab kev tsis xis nyob.

Leej twg yuav tsum tsis txhob coj

Ribavirin yog contraindicated nyob rau hauv cov neeg muaj lub siab ntev mus rau ribavirin lossis rau ib qho ntawm kev zam, thaum pub niam mis, hauv cov neeg uas muaj keeb kwm yav dhau los ntawm cov kab mob plawv mob siab, suav nrog tsis khov lossis tswj tsis tau tus mob plawv, hauv rau lub hlis dhau los, cov neeg muaj mob qog mob hnyav lossis mob rau lub cev cirrhosis thiab hemoglobinopathies.

Kev pib ntawm interferon kev kho yog contraindicated nyob rau hauv cov neeg mob sib koom kis tus kab mob siab C thiab HIV, nrog mob qog ntshav thiab nrog Child-Pugh qhab nia ≥ 6.

Tsis tas li, cov tshuaj yuav tsum tsis txhob siv los ntawm cov poj niam cev xeeb tub thiab yuav tsum tsuas yog pib tom qab tau txais qhov tshwm sim tsis zoo ntawm kev ntsuas cev xeeb tub uas nqa tawm tam sim ua ntej pib kho.