Narcolepsy: nws yog dab tsi, cov tsos mob thiab kev kho mob

Zoo Siab

• Cov tsos mob ntawm narcolepsy
• Yuav kho tus mob li cas

Narcolepsy yog ib qho muaj mob uas ua rau muaj kev hloov pauv hauv kev pw tsaug zog, uas tus neeg lub sijhawm tsaug zog ntau dhau hnub thiab muaj peev xwm pw tsaug zog lub suab tau txhua lub sijhawm, suav nrog thaum sib tham lossis txawm nres nyob hauv nruab nrab ntawm cov tsheb.

Cov laj thawj ntawm narcolepsy cuam tshuam txog qhov poob ntawm cov neurons hauv ib cheeb tsam ntawm lub hlwb hu ua hypothalamus, uas tsim cov khoom hu ua hypocretin, uas yog neurotransmitter lub luag haujlwm rau kev tswj hwm arousal thiab wakeness, uas sib raug rau kev ceev faj, ua rau tib neeg pom zoo. Nrog kev tuag ntawm cov neurons no, muaj tsawg lossis tsis tau tsim cov tshuaj hypocretin thiab, yog li ntawd, tib neeg muaj peev xwm tsaug zog yooj yim.

Kev kho ntawm narcolepsy yuav tsum tau qhia los ntawm tus kws kho mob hlwb, thiab kev siv cov tshuaj uas ua rau ncaj qha ntawm cov tsos mob, tswj tus kab mob, feem ntau yog qhia.

Cov tsos mob ntawm narcolepsy

Thawj thiab lub cim tseem ceeb ntawm narcolepsy yog pw tsaug zog ntau dhau hnub. Txawm li cas los xij, raws li daim paib no tsis muaj tseeb, kev kuaj mob tsis tau, uas ua rau cov hypocretin tsawg dua thiab tsawg dua, ua rau muaj qhov tshwm sim ntawm lwm cov tsos mob thiab cov tsos mob, xws li:

• Lub sijhawm pheej pw tsaug zog thaum nruab hnub, thaum tus neeg muaj peev xwm tsaug zog yooj yim nyob txhua qhov chaw, tsis hais lawv yuav ua dab tsi;
• Cov leeg tsis muaj zog, tseem hu ua cataplexy, uas vim yog cov leeg ua kom tsis muaj zog, tus neeg yuav poob thiab tsis tuaj yeem hais lus lossis txav mus los, txawm hais tias nco qab. Cataplexy yog qhov kev mob tshwj xeeb ntawm narcolepsy, txawm li cas los xij tsis yog txhua tus muaj;
• Kev ua si, uas tuaj yeem hnov ​​suab lossis pom;
• Lub cev tuag tes tuag taw thaum sawv, uas tus neeg txav tsis taus mus li ob peb feeb. Feem ntau, pw tsaug zog tuag tes tuag taw ntu hauv narcolepsy kawg li ntawm 1 mus rau 10 feeb;
• Fragmented pw tsaug zog thaum hmo ntuj, uas tsis cuam tshuam nrog tus neeg lub sijhawm pw tsaug zog ib hnub.

Kev kuaj mob ntawm tus mob narcolepsy yog tsim los ntawm tus kws kho paj hlwb thiab tus kws kho mob pw tsaug zog raws li kev txheeb xyuas ntawm cov cim thiab cov tsos mob qhia los ntawm tus neeg. Tsis tas li ntawd, kev ntsuam xyuas xws li polysomnography thiab ntau qhov kev ntsuam xyuas latency tau ua los kawm cov haujlwm hauv lub hlwb thiab pw tsaug zog lub sijhawm ntev. Hypocretin ntau npaum li cas kuj qhia tau tias txhua yam kev sib raug zoo nrog cov tsos mob tau txheeb xyuas thiab, yog li, kev kuaj mob ntawm tus mob narcolepsy tuaj yeem lees paub.

Yuav kho tus mob li cas

Kev kho mob ntawm narcolepsy yuav tsum tau qhia los ntawm tus kws kho mob hlwb thiab tuaj yeem ua nrog cov tshuaj, xws li Provigil, Methylphenidate (Ritalin) lossis Dexedrine, uas muaj cov haujlwm ntawm kev txhawb cov neeg mob hlwb kom nyob twj ywm.

Qee qhov kev tawm tsam tshuaj tua kab mob, xws li Fluoxetine, Sertaline lossis Protriptyline, tuaj yeem pab txo qis ntu kev mob cataplexy lossis mob tso quav. Lub Xyrem tshuaj kuj tseem siv tau tshuaj rau qee cov neeg mob siv thaum hmo ntuj.

Kev kho mob ntuj rau narcolepsy yog hloov koj txoj kev ua neej thiab noj zaub mov zoo, kom tsis txhob noj zaub mov hnyav, npaj sijhawm pw tom qab noj mov, zam kev haus dej haus cawv lossis lwm yam tshuaj uas ua rau pw tsaug zog.