Ketamine puas tuaj yeem pab kho kev nyuaj siab?
Zoo Siab
Kev nyuaj siab ntau dua li koj xav. Nws cuam tshuam ntau dua 15 lab tus neeg Asmeskas, thiab Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv (World Health Organization) kwv yees tias tus lej loj hlob mus txog 300 lab thaum koj nthuav dav thoob ntiaj teb. Muaj ntau txoj kev kho mob sib txawv uas muaj los pab txo nws cov tsos mob-xav kev ntxhov siab, insomnia, qaug zog, thiab tsis qab los noj mov ntawm lwm tus-nrog cov kev kho mob feem ntau yog serotonin reuptake inhibitors (lossis SSRIs). Tab sis txij li xyoo 2000, cov kws kho mob thiab cov kws tshawb fawb tau sim nrog ketamine-thaum chiv keeb tshuaj tswj kev mob, tam sim no raug tsim txom los ntawm kev siv tshuaj vim tias nws cov teebmeem hallucinogenic-raws li lwm txoj hauv kev los kho tus mob, raws li Ruben Abagyan, Ph.D. , tus kws qhia tshuaj kho mob ntawm University of California San Diego (UCSD).
Tej zaum koj xav, "Tos! Dab tsi?" Yog tias koj tau hnov txog ketamine, tseem hu ua Special K, koj paub tias nws tsis muaj dab tsi los yog cov tshuaj OTC. Qhov tseeb, nws tau paub tias yog tshuaj loog tsis zoo (txhais tau tias yog tshuaj uas cuam tshuam kev nkag siab ntawm kev pom thiab lub suab, thaum tsim cov kev xav ntawm kev cais tawm ntawm tus kheej thiab ib puag ncig). Feem ntau yog siv los ntawm kws kho tsiaj los kho qhov mob hauv tsiaj, tab sis nws kuj tseem tuaj yeem hais qhia rau tib neeg rau kev tswj hwm qhov mob hnyav, tshwj xeeb yog cov uas muaj teeb meem neuropathic, ib hom mob hlab ntsha ntev, raws li kev tshawb fawb xyoo 2014 luam tawm hauv British Phau Ntawv Tshuaj Kho Mob.
"Nws tau paub tias qhov mob thiab kev nyuaj siab tau txuas nrog," hais tias Isaac Cohen, tus kws muag tshuaj uas ua haujlwm ntawm txoj kev tshawb no. Nws tau hais tias "Cov neeg muaj kev nyuaj siab feem ntau nyob ntawm qhov mob thiab cov neeg mob ntev yuav muaj kev nyuaj siab ntau vim tias tsis muaj kev txav mus los, tsis muaj peev xwm qoj ib ce, thiab lwm yam," Ketamine yog qhov tshwj xeeb vim tias nws tuaj yeem kho qhov mob thiab kev nyuaj siab ib txhij, ua rau muaj txiaj ntsig zoo dua rau ob qho xwm txheej. "Thiab tam sim no cov kws tshawb fawb tau sib cav tias tsis yog ib qho pov thawj tseeb xwb, tab sis kuj tseem muaj cov ntaub ntawv txheeb cais uas qhia tias ketamine tuaj yeem pab txo cov tsos mob ntawm kev nyuaj siab.
Nyob rau hauv thawj- puas tau loj-scale tsom xam ntawm nws hom, luam tawm nyob rau hauv Xwm, cov kws tshawb fawb pom tau tias cov neeg mob uas tau txais ketamine tau qhia txog qhov txo qis ntawm kev nyuaj siab. Qhov kev tshawb fawb no, ua los ntawm Lub Tsev Kawm Ntawv Kws Tshuaj thiab Kws Tshuaj Kho Mob ntawm UCSD, txhawb ntxiv cov ntaub ntawv keeb kwm thiab cov kev tshawb fawb pej xeem me me uas tseem tau qhia txog ketamine's antidepressive teebmeem.
Dab tsi teeb tsa ketamine sib nrug los ntawm lwm yam kev kho mob, tshwj xeeb, yog sai npaum li cas nws thiaj siv tau. Abaygan hais tias "Tam sim no kev kho mob pom zoo los ntawm FDA rau kev nyuaj siab poob rau ntau lab vim tias lawv tsis ua haujlwm nrawm txaus," Ketamine ua haujlwm tsis pub dhau teev. Qhov ntawd yog qhov tsawg dua li SSRIs, piv txwv li, uas tuaj yeem siv sijhawm rau mus rau kaum lub lis piam kom ncav cuag lawv lub peev xwm. Thiab qhov sib txawv ntawm lub sijhawm tuaj yeem yog qhov teeb meem ntawm lub neej lossis kev tuag, tshwj xeeb tshaj yog cov neeg uas muaj kev xav tua tus kheej.
Rau lawv cov kev tshawb fawb, Abaygan thiab nws pab neeg tau tshuaj xyuas cov ntaub ntawv los ntawm FDA's Adverse Event Report System, ib lub koom haum uas sau cov ntaub ntawv hais txog kev tsis zoo (lossis tsis txhob txwm ua phem rau txhua yam) ntawm cov tshuaj pom zoo uas tau tshaj tawm los ntawm cov kws muag tshuaj thiab kws kho mob. Tshwj xeeb, lawv pom 40,000 tus neeg mob uas tau muab tshuaj rau qhov mob thiab cais lawv ua ob pawg-cov neeg uas tau noj ketamine thiab cov tshuaj kho mob lwm yam (tsis suav nrog NSAIDs).
Cov txiaj ntsig tau pom qhov tseem ceeb "khoom plig," txawm tias tsis xav tau, cuam tshuam. Ib nrab ntawm cov neeg uas kho lawv qhov mob nrog ketamine tau tshaj tawm tias muaj kev nyuaj siab tsawg dua li cov uas tau siv lwm hom tshuaj txo qhov mob. Txawm hais tias peb tsis paub tias ib tus ntawm cov neeg mob no, tshwj xeeb tshaj yog cov neeg ntawm ketamine, tau ntsib cov tsos mob ntawm kev nyuaj siab ua ntej noj cov tshuaj, qhov txiaj ntsig zoo ntawm lub siab, nrog rau kev sib txuas ntawm qhov mob thiab kev nyuaj siab, tuaj yeem lav kev sib tham ntxiv txog kev siv ketamine. kho kev nyuaj siab ntau dua.
Raws li cov kws tshawb fawb, ketamine yog tus nqi pheej yig thiab yog tias koj twb tau sim tsawg kawg peb lwm yam tshuaj tiv thaiv kev nyuaj siab uas tsis ua tiav, feem ntau nws tau them los ntawm feem ntau cov phiaj xwm kev pov hwm kev noj qab haus huv. Point yog? Tsis txhob maj sau tawm ketamine ib yam li cov hallucinogen. Tej zaum nws yuav yog qhov tshwj xeeb tom qab tag nrho. (Thiab yog tias tsis muaj dab tsi ntxiv, hais mav, txheeb xyuas cov no los tswj kev ntxhov siab lossis kev nyuaj siab thaum twg los xij.)