Alpha-1 Antitrypsin Kev Xeem

Zoo Siab

• Qhov kev ntsuam xyuas alpha-1 antitrypsin (AAT) yog dab tsi?
• Nws siv rau dab tsi?
• Vim li cas kuv thiaj li yuav tsum tau kuaj AAT?
• Yuav ua li cas thaum lub sijhawm xeem AAT?
• Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?
• Puas muaj kev pheej hmoo rau kev kuaj?
• Cov txiaj ntsig li cas?
• Puas muaj lwm yam ntxiv uas kuv xav paub txog qhov kev xeem AAT?
• Ua tim khawv

Qhov kev ntsuam xyuas alpha-1 antitrypsin (AAT) yog dab tsi?

Kev ntsuam xyuas no ntsuas tus nqi alpha-1 antitrypsin (AAT) hauv cov ntshav. AAT yog cov protein ua hauv lub siab. Nws pab tiv thaiv koj lub ntsws los ntawm kev puas tsuaj thiab kab mob, xws li mob ntsws thiab mob ntsws ntsws (COPD).

AAT yog tsim los ntawm qee cov caj ces hauv koj lub cev. Cov noob yog qhov tseem ceeb ntawm caj ces dhau los ntawm koj niam koj txiv. Lawv nqa cov ntaub ntawv uas txiav txim siab koj cov xeeb ceem tshwj xeeb, xws li qhov siab thiab xim qhov muag. Txhua tus tau txais ob daim ntawv theej ntawm cov gene uas ua rau AAT, ib daim ntawv los ntawm lawv txiv thiab ib daim ntawv los ntawm lawv niam. Yog tias muaj kev hloov (hloov) hauv ib los yog ob daim ntawv theej ntawm cov gene, koj lub cev yuav ua kom tsawg AAT lossis AAT uas tsis ua haujlwm zoo li nws yuav tsum tau ua.

• Yog koj muaj ob daim hloov pauv ntawm cov gene, nws txhais tau tias koj muaj ib qho mob hu ua AAT deficiency. Cov neeg muaj tus mob no yuav muaj feem ntau yuav mob ntsws lossis daim siab ua ntej muaj hnub nyoog 45 xyoos.
• Yog tias koj muaj ib tug hloov tau AAT noob, tej zaum koj yuav muaj feem tsawg ntawm cov lej ntawm AAT, tab sis me me lossis tsis muaj tsos mob tshwm sim. Cov tib neeg muaj ib tus noob hloov tau yog cov xeeb ntawm AAT tsis muaj peev xwm. Qhov no txhais tau tias koj tsis muaj tus mob no, tab sis koj tuaj yeem faib cov noob hloov pauv rau koj cov menyuam.

Kev kuaj AAT tuaj yeem pab qhia tau yog tias koj muaj kev hloov caj ces uas ua rau koj muaj kev pheej hmoo rau tus kabmob.

Lwm lub npe: A1AT, AAT, alpha-1-antiprotease deficiency, α1-antitrypsin

Nws siv rau dab tsi?

Kev ntsuam xyuas AAT feem ntau yog siv los pab kuaj mob AAT tsis txaus rau cov neeg uas muaj mob ntsws thaum muaj hnub nyoog (45 xyoo lossis qis dua) thiab tsis muaj lwm yam kev pheej hmoo xws li haus luam yeeb.

Kuaj kuj tseem yuav raug siv coj mus kuaj pom ib qho tshwm sim muaj tsawg kawg ntawm daim siab ua mob rau cov menyuam mos.

Vim li cas kuv thiaj li yuav tsum tau kuaj AAT?

Koj yuav tsum tau kuaj AAT yog tias koj muaj hnub nyoog qis dua 45 xyoos, tsis yog haus luam yeeb, thiab muaj tsos mob ntsws, nrog rau:

• Hawb pob
• Ua tsis taus pa
• Mob khaub thuas hnoos
• Sai dua lub plawv nres thaum koj sawv
• Cov teeb meem tsis pom kev
• Hawb pob uas tsis teb tau zoo rau kev kho mob

Koj kuj tseem yuav tau txais qhov kev ntsuas no yog tias koj muaj keeb kwm tsev neeg tsis taus AAT.

AAT tsis muaj peev xwm ua rau menyuam yaus feem ntau cuam tshuam rau daim siab. Yog li koj tus menyuam yuav xav kuaj AAT yog tias nws tus kws saib xyuas kev noj qab haus huv pom pom cov tsos mob ntawm daim siab. Cov no suav nrog:

• Qhov muag daj tawv nqaij daj daj, muaj tawv nqaij daj thiab tawv muag uas ntev dua li ib asthiv lossis ob zaug
• Ib tus mob spleen
• Nquag khaus

Yuav ua li cas thaum lub sijhawm xeem AAT?

Tus kws kho mob yuav kuaj ntshav ntawm txoj hlab ntshav hauv koj txhais caj npab, siv rab koob me me. Tom qab cov koob raug tso nkag, cov ntshav me me yuav raug sau rau hauv lub khob kuaj lossis vial. Koj tuaj yeem hnov ​​me ntsis thaum cov koob nkag mus lossis tawm. Qhov no feem ntau yuav siv sijhawm tsawg dua tsib feeb.

Kuv puas yuav tau ua ib yam dab tsi txhawm rau npaj rau qhov kev xeem?

Koj tsis tas yuav npaj tshwj xeeb rau kev xeem AAT.

Puas muaj kev pheej hmoo rau kev kuaj?

Nws muaj feem yuav ua rau nws lub cev muaj feem ntau yam tsawg uas nws yuav kuaj ntshav. Koj yuav muaj mob me lossis doog ntshav ntawm qhov chaw tso rab koob, tab sis feem ntau cov tsos mob ploj mus sai.

Cov txiaj ntsig li cas?

Yog tias koj cov txiaj ntsig tau qhia qis dua li ntawm AAT ib txwm, nws yuav txhais tau tias koj muaj ib lossis ob lub cim hloov AAT. Qhov qis dua theem, qhov yuav muaj ntau yog koj muaj ob lub noob hloov pauv thiab AAT tsis muaj peev xwm.

Yog tias koj raug kuaj pom tias muaj AAT tsis muaj peev xwm, koj tuaj yeem ua cov kauj ruam los txo koj txoj kev pheej hmoo ntawm tus mob. Cov no suav nrog:

• Tsis haus luam yeeb. Yog tias koj yog neeg haus luam yeeb, txiav luam yeeb. Yog koj tsis haus luam yeeb, tsis txhob pib. Kev haus luam yeeb yog qhov uas yuav ua rau muaj kev phom sij rau lub ntsws muaj sia nyob rau cov neeg muaj AAT tsis txaus.
• Ua raws li kev noj qab haus huv zoo
• Ua kom ib ce muaj zog tas li
• Mus ntsib koj tus kws kho mob tsis tu ncua
• Noj tshuaj raws li koj tus kws kho mob hais

Yog koj muaj lus nug txog koj cov txiaj ntsig, nrog koj tus kws kho mob tham.

Kawm paub ntau ntxiv txog cov kev sim hauv chaw soj ntsuam, cov chaw siv ntsuas, thiab nkag siab cov txiaj ntsig tau.

Puas muaj lwm yam ntxiv uas kuv xav paub txog qhov kev xeem AAT?

Ua ntej pom zoo kom mus kuaj, nws yuav pab hais lus nrog tus kws sab laj tswv yim caj ces. Tus kws pab tswv yim txog caj ces yog tus kws tshaj lij kawm tiav los ntawm kev tshawb fawb caj ces thiab kev tshuaj ntsuam caj ces. Tus kws pab tswv yim tuaj yeem pab koj nkag siab txog cov kev pheej hmoo thiab cov txiaj ntsig ntawm kev xeem ntawv. Yog tias koj raug sim, ib tus kws pab tswv yim tuaj yeem pab koj nkag siab cov txiaj ntsig thiab muab cov ntaub ntawv qhia txog kev mob, nrog rau koj qhov kev pheej hmoo kis tus kabmob mus rau koj cov menyuam.

Ua tim khawv

1. Kev Tshuaj Ntsuam Xyuas online [Internet]. Washington D.C .: Koom Haum Asmeskas Rau Chaw Kuaj Mob; c2001–2019. Alpha-1 Antitrypsin; [hloov tshiab 2019 Jun 7; hais tawm 2019 Oct 1]; [txog 2 ntxaij]. Muaj los ntawm: https://labtestsonline.org/tests/alpha-1-antitrypsin
2. Kev Tshuaj Ntsuam Xyuas online [Internet]. Washington D.C .: Koom Haum Asmeskas Rau Chaw Kuaj Mob; c2001–2019. Cov kua muag daj; [kho tshiab 2018 Feb 2; hais tawm 2019 Oct 1]; [txog 3 ntxaij]. Muaj los ntawm: https://labtestsonline.org/conditions/jaundice
3. Merck Los Ntawm Cov Neeg Siv Khoom Siv [Internet]. Kenilworth (NJ): Merck & Co. Inc .; c2019. Alpha-1 Antitrypsin Qhov Tsis Txaus; [kho tshiab 2018 Nov; raug nplua 2019 Oct 1]; [txog 2 ntxaij]. Muaj los ntawm: https://www.merckmanuals.com/home/lung-and-airway-disorders/chronic-obstructive-pulmonary-disease-copd/alpha-1-antitrypsin-deficiency?query=alpha-1%20antitrypsin
4. Teb Chaws Lub Plawv, Lub Ntsws, thiab Koom Haum Ntshav [Internet]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Alpha-1 Antitrypsin Qhov Tsis Txaus; [hais tawm 2019 Oct 1]; [txog 2 ntxaij]. Muaj los ntawm: https://www.nhlbi.nih.gov/health-topics/alpha-1-antitrypsin-deficiency
5. Teb Chaws Lub Plawv, Lub Ntsws, thiab Koom Haum Ntshav [Internet]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Kuaj ntshav; [hais tawm 2019 Oct 1]; [txog 3 ntxaij]. Muaj los ntawm: https://www.nhlbi.nih.gov/health-topics/blood-tests
6. NIH Lub Tebchaws Asmeskas Cov Tsev Kuaj Tshuaj (Genetics) Hauv Tsev [Hauv Is Taws Nem]. Bethesda (MD): Asmeskas Lub Chaw Haujlwm Saib Xyuas Kev Noj Qab Haus Huv thiab Tib Neeg; Lub noob no yog dab tsi ?; 2019 Oct 1 [qhia tawm 2019 Oct 1]; [txog 3 ntxaij]. Muaj los ntawm: https://ghr.nlm.nih.gov/primer/basics/gene
7. Kev Noj Qab Haus Huv UF: University of Florida Health [Is Taws Nem]. Gainesville (IBCE): University of Florida Kev Noj Qab Haus Huv; c2019. Alpha-1 antitrypsin kev kuaj ntshav: Txheej txheem cej luam; [kho tshiab 2019 Oct 1; raug nplua 2019 Oct 1]; [txog 2 ntxaij]. Muaj los ntawm: https://ufhealth.org/alpha-1-antitrypsin-blood-test
8. University of Rochester Medical Center [Internet]. Rochester (NY): Tsev kawm qib siab Rochester Medical Center; c2019. Cov Kws Kho Mob Kev Noj Qab Haus Huv: Alpha-1 Antitrypsin; [hais tawm 2019 Oct 1]; [txog 2 ntxaij]. Muaj los ntawm: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=alpha_1_antitrypsin
9. UW Kev Noj Qab Haus Huv [Is Taws Nem]. Madison (WI): University of Wisconsin Cov Tsev Kho Mob thiab Chaw Kho Mob; c2019. Alpha-1 Antitrypsin Kev Tshawb Fawb Hauv Tshuaj Ntsuas: Alpha-1 Antitrypsin Qhov Tsis Txaus ?; [kho tshiab 2018 Sep 5; raug nplua 2019 Oct 1]; [txog 2 ntxaij]. Muaj los ntawm: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html
10. UW Kev Noj Qab Haus Huv [Is Taws Nem]. Madison (WI): University of Wisconsin Cov Tsev Kho Mob thiab Chaw Kho Mob; c2019. Alpha-1 Antitrypsin Kev Tshawb Fawb Hauv Tshuaj: Qhov kev qhuab ntuas caj ces yog dab tsi ?; [kho tshiab 2018 Sep 5; raug nplua 2019 Oct 1]; [txog 7 ntxaij]. Muaj los ntawm: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html#tv8548
11. UW Kev Noj Qab Haus Huv [Is Taws Nem]. Madison (WI): University of Wisconsin Cov Tsev Kho Mob thiab Chaw Kho Mob; c2019. Alpha-1 Antitrypsin Kev Tshawb Fawb Hauv Tshuaj Ntsuas: Vim Li Cas Kuv Thiaj Tsis Raug Kuaj Xyuas ?; [kho tshiab 2018 Sep 5; raug nplua 2019 Oct 1]; [txog 6 ntxaij]. Muaj los ntawm: https://www.uwhealth.org/health/topic/special/alpha-1-antitrypsin-deficiency-genetic-testing/uf6753.html#uf6790

Cov ntaub ntawv ntawm lub xaib no yuav tsum tsis txhob siv los hloov chaw kho mob lossis tswv yim kho mob. Hu rau kws kho mob yog tias koj muaj lus nug txog koj txoj kev noj qab haus huv.