Saquinavir

Zoo Siab

• Ua ntej noj saquinavir,
• Saquinavir yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:
• Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

Saquinavir yog siv ua ke nrog ritonavir (Norvir) thiab lwm yam tshuaj los kho tib neeg cov tshuaj tiv thaiv tus kabmob HIV (HIV). Saquinavir yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua protease inhibitors. Nws ua haujlwm los ntawm kev txo qis hauv cov HIV hauv cov ntshav. Txawm hais tias saquinavir tsis kho HIV, nws yuav txo koj txoj hmoo los ntawm kev tiv thaiv kab mob (AIDS) thiab mob ntsig txog HIV xws li muaj mob hnyav lossis mob qog ntshav. Siv cov tshuaj no nrog rau kev xyaum pw ua ke kom nyab xeeb thiab hloov pauv lwm yam hauv lub neej yuav txo qhov kev pheej hmoo kis tus mob HIV mus rau lwm tus neeg.

Saquinavir los ua tshuaj ntsiav thiab lub ntsiav tshuaj los noj ntawm qhov ncauj. Nws feem ntau noj tib lub sijhawm xws li ritonavir (Norvir) ob zaug hauv ib hnub hauv 2 teev tom qab noj mov tag. Nws yuav yooj yim dua kom nco qab noj saquinavir yog tias koj noj nrog zaub mov noj. Siv saquinavir nyob ib ncig ntawm tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj saquinavir raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Nqos cov ntsiav tshuaj tag nrho; tsis txhob zom, los yog zom lawv.

Yog tias koj tsis tuaj yeem nqos cov tshuaj ntsiav tag nrho, koj tuaj yeem noj saquinavir los ntawm kev qhib lub tshuaj ntsiav thiab sib xyaw cov ntsiab lus nrog cov kua qab zib, sorbitol, lossis jam. Txhawm rau npaj txhua koob tshuaj, ntxiv 3 me nyuam diav (15 mL) ntawm cov suab thaj, sorbitol, lossis jam rau hauv cov taub ntim. Qhib cov tshuaj tsaug saquinavir thiab ntxiv cov khoom rau hauv lub khob. Do cov sib tov rau 30 rau 60 vib nas this. Yog tias koj siv cov khaub thuas txias, sorbitol, lossis jam, tos kom muaj qhov sib tov tuaj hauv chav sov ua ntej noj. Nco ntsoov noj cov khoom sib tov kom koj tau txais cov tshuaj puv.

Txuas ntxiv noj saquinavir txawm hais tias koj xis neej. Tsis txhob tsum tsis txhob noj saquinavir yam tsis tau tham nrog koj tus kws kho mob. Yog tias koj tsis nco qab noj ntau dua, noj tsawg tshaj li qhov tau hais tseg lossis tsum tsis noj cov tshuaj saquinavir, koj tus mob yuav nyuaj kho.

Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia txog cov neeg mob rau koj (Kev Siv Tshuaj) thaum koj pib kho nrog saquinavir thiab txhua zaus koj rov ntim tshuaj rau koj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib tau Chaw Tswj Xyuas Khoom Noj thiab Tshuaj (FDA) lub vev xaib (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) lossis cov chaw tsim tshuaj paus lub vev xaib kom tau txais Kev Qhia Tshuaj.

Qee zaum Saquinavir siv nrog ritonavir (Norvir) thiab lwm yam tshuaj los pab tiv thaiv kev kis kab mob hauv cov neeg ua haujlwm kho mob lossis lwm tus neeg kis tus kabmob HIV. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev noj cov tshuaj no rau koj tus mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj saquinavir,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau saquinavir, lwm yam tshuaj, lactose, lossis lwm yam tshuaj hauv saquinavir tsiav tshuaj lossis ntsiav tshuaj. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj saquinavir. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob yog tias koj noj ib qho tshuaj hauv qab no: alfuzosin (Uroxatral); atazanavir (Reyataz, hauv Evotaz); clarithromycin (Biaxin, hauv Prevpac); clozapine (Clozaril, Fazaclo, Versacloz); dasatinib (Sprycel); cov tshuaj ergot xws li dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Ergomar, hauv Cafergot, hauv Migergot, lwm tus), thiab methylergonovine (Methergine); erythromycin (E.E.S., E-mycin, Erythrocin, lwm tus); halofantrine; haloperidol (Haldol); qee yam tshuaj rau lub plawv dhia tsis xwm yeem xws li amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), lidocaine (Xylocaine), propafenone (Rhythmol), thiab quinidine (hauv Nuedexta); lovastatin (Altoprev); lurasidone (Latuda); tshuaj rau kev mob hlwb thiab xeev siab xws li chlorpromazine, thiab thioridazine; midazolam los ntawm qhov ncauj; pentamidine (Nebupent, Pentam); pimozide (Orap); quinine (Qualaquin); phom phom (Rifadin, Rimactane, hauv Rifamate, Rifater); sildenafil (tsuas yog Revatio hom siv rau mob ntsws); simvastatin (Zocor, Flolopid, hauv Vytorin); sunatinib (Sutent); tacrolimus (Astagraf XL, Envarsus XR, Prograf); trazodone; triazolam (Halcion); lossis ziprasidone (Geodon). Kuj qhia koj tus kws kho mob lossis kws muag tshuaj yog tias koj noj rilpivirine (Edurant, hauv Juluca, Odefsey, Complera) lossis yog tias koj tau txiav tsis noj nws hauv ob lub lis piam dhau los. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj tshuaj saquinavir yog tias koj noj ib lossis ntau dua ntawm cov tshuaj no.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob sau tseg thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, thiab cov khoom noj zoo uas koj noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: anticoagulants ('ntshav thinners') xws li warfarin (Coumadin, Jantoven); cov tshuaj tiv thaiv xws li itraconazole (Onmel, Sporanox) thiab ketoconazole benzodiazepines xws li alprazolam (Xanax), clorazepate (Gen-Xene, Tranxene), diazepam (Diastat, Valium), thiab flurazepam; beta blockers xws li atenolol (Tenormin, hauv Tenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, hauv Dutoprol, hauv Loressor HCT), nadolol (Corgard, hauv Corzide), thiab propranolol (Hemangeol, Inderal, Innopran); bosentan (Tracleer); calcium channel blockers xws li amlodipine (Norvasc, hauv Caduet, Lotrel, lwm tus), diltiazem (Cardizem, Cartia, Tiazac, lwm tus), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), nimodipine (Nymalize) ), nisoldipine (Sular), thiab verapamil (Calan, Verelan, hauv Tarka); qee yam tshuaj ua kom ntshav roj (statins) xws li atorvastatin (Lipitor, hauv Caduet); cobicistat (Tybost, hauv Evotaz, Genvoya, Prezcobix, thiab Stribild); corticosteroids xws li betamethasone, budesonide (Entocort, Pulmicort, Uceris, hauv Symbicort), ciclesonide (Alvesco, Zetonna, Omnaris), dexamethasone, fluticasone (Arnuity Ellipta, Flonase, Flovent, hauv Advair, lwm tus), methylprednisone ), prednisone (Rayos), thiab triamcinolone (Kenalog); colchicine (Colcrys, Mitigare); digoxin (Lanoxin); fentanyl (Abstral, Actiq, Duragesic, lwm tus); qee yam tshuaj tiv thaiv kab mob xws li cyclosporine (Gengraf, Neoral, Sandimmune), thiab sirolimus (Rapamune); cov tshuaj los kho HIV lossis AIDS nrog rau indinavir (Crixivan), lopinavir nrog ritonavir (Kaletra), maraviroc (Selzentry), nelfinavir (Viracept), lossis tipranavir nrog ritonavir (Aptivus); qee cov tshuaj noj rau lub plawv dhia tsis xwm yeem xws li ibutilide (Kho), thiab sotalol (Betapace, Sorine, Sotylize); cov tshuaj los kho mob chua leeg xws li carbamazepine (Carbatrol, Epitol, Tegretol, lwm tus), phenytoin (Dilantin, Phenytek), thiab phenobarbital; tshuaj txiav yeeb (Dolophine, Methadose); nefazodone; omeprazole (Prilosec, hauv Yosprela, Zegerid); qee yam phosphodiesterase (PDE5) inhibitors xws li sildenafil (Viagra), tadalafil (Adcirca, Cialis), thiab vardenafil (Levitra, Staxyn); quetiapine (Seroquel); quinupristin thiab dalfopristin (Synercid); rifabutin (Mycobutin); salmeterol (Serevent, hauv Advair); thiab qee yam tricyclic tshuaj tua kab mob suav nrog amitriptyline, clomipramine (Anafranil), imipramine (Surmontil, Tofranil), thiab maprotiline. Lwm cov tshuaj yuav cuam tshuam nrog saquinavir, yog li nco ntsoov qhia koj tus kws kho mob thiab kws muag tshuaj txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia koj tus kws kho mob tias yam tshuaj ntsuab koj noj lossis npaj yuav noj dab tsi, tshwj xeeb tshaj yog St. John lub wort, thiab qej tsiav tshuaj.
• qhia rau koj tus kws kho mob yog tias koj haus dej lossis haus cawv ntau dhau, thiab yog tias koj lossis ib tus neeg hauv koj tsev neeg muaj lossis muaj mob ntshav qab zib. Kuj qhia koj tus kws kho mob yog tias koj tau lossis muaj lub plawv dhia tsis xwm yeem, cov roj (cholesterol) lossis triglycerides (rog hauv cov ntshav); hemophilia (ib qho kev los ntshav); tej yam mob uas lub cev tsis tuaj yeem tsim tau lactase txaus lossis tsis tuaj yeem tiv thaiv lactose, lossis mob plawv lossis raum.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Yog tias koj cev xeeb tub thaum noj cov tshuaj saquinavir, hu rau koj tus kws kho mob. Koj yuav tsum tsis txhob pub mis niam yog tias koj muaj tus kabmob HIV lossis noj tshuaj saquinavir.
• koj yuav tsum paub tias saquinavir tuaj yeem txo qhov kev muaj txiaj ntsig ntawm kev tswj kom tsis txhob muaj menyuam (kev tswj kom tsis txhob muaj menyuam, tshuaj pleev ib ce, ncig, lossis txhaj tshuaj). Tham nrog koj tus kws kho mob txog kev siv lwm txoj kev tswj tsis pub muaj menyuam.
• yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws khomob lossis kws kho hniav tias koj noj saquinavir.
• koj yuav tsum paub tias koj lub cev rog tuaj yeem nce lossis txav mus rau thaj chaw ntawm koj lub cev, xws li koj sab nraub qaum, caj dab ('' twm hump ''), ob lub mis, thiab ib puag ncig koj lub plab. Koj tuaj yeem pom ib qho ploj ntawm lub cev rog ntawm koj lub ntsej muag, ceg thiab caj npab.
• koj yuav tsum paub tias koj tuaj yeem ntsib hyperglycemia (nce hauv koj cov piam thaj hauv ntshav) thaum koj tseem noj cov tshuaj no, txawm tias koj tsis tau muaj ntshav qab zib. Qhia rau koj tus kws kho mob tam sim ntawd yog tias koj muaj cov tsos mob hauv qab no thaum koj noj saquinavir: nqhis dej heev, tso zis heev, tshaib plab heev, plooj tsis pom kev, lossis tsis muaj zog. Nws yog ib qho tseem ceeb heev uas yuav tau hu rau koj tus kws kho mob sai li sai tau uas koj muaj cov tsos mob no, vim tias cov ntshav qab zib uas tsis tau kho nws tuaj yeem ua rau mob hnyav hu ua ketoacidosis. Ketoacidosis tuaj yeem dhau los ua neeg muaj sia nyob yog tias tsis kho thaum ntxov. Cov tsos mob ntawm ketoacidosis suav nrog qhov ncauj qhuav, xeev siab thiab ntuav, ua pa luv, ua pa uas hnov ​​tsw thiab tsis nco qab.
• koj yuav tsum paub tias thaum koj tab tom noj tshuaj los kho kab mob HIV, koj lub cev tiv thaiv kab mob yuav muaj zog thiab pib tawm tsam lwm yam kev mob uas twb muaj hauv koj lub cev lossis ua rau lwm yam mob tshwm sim. Qhov no tuaj yeem ua rau koj tsim cov tsos mob ntawm cov mob lossis cov mob. Yog tias koj muaj cov tsos mob tshiab lossis mob hnyav tom qab pib kho nrog saquinavir, nco ntsoov qhia koj tus kws kho mob.

Tham nrog koj tus kws kho mob txog kev noj txiv kab ntxwv qaub thiab haus kua txiv thaum lub sijhawm noj cov tshuaj no.

Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Saquinavir yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• zawv plab
• mob plab
• xeev siab
• ntuav
• cem quav
• nkees nkees
• rov qab mob
• daim di ncauj los yog tawv nqaij qhuav
• ua npaws

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:

• xoo pob, khaus, o ntawm lub qhov muag, ntsej muag, qhov ncauj, caj pas, lossis daim di ncauj, ua pa nyuaj lossis nqos khoom
• blistering lossis tev tawv nqaij
• daj tawm ntawm daim tawv nqaij lossis qhov muag, tsis qab los noj mov, khaub thuas zoo li cov tsos mob, nkees dhau heev, tso zis dub, tso quav tso quav, mob rau sab xis sab xis ntawm lub plab.
• kiv taub hau, lub teeb taws me me, qeeb, ua ntu zus, lossis txhaws lub plawv dhia, tsaus muag

Saquinavir yuav ua rau muaj kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum koj tseem noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

• caj pas mob

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj sim ua ntej thiab thaum kho koj lub cev kom tshawb xyuas koj lub cev cov lus teb rau saquinavir. Koj tus kws kho mob kuj tuaj yeem xaj hluav taws xob (ECG; ntsuas ntsuas qhov ntsuas hluav taws xob hauv plawv) ua ntej thiab thaum kho koj.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Invirase^®