Acalabrutinib

Zoo Siab

• Ua ntej noj acalabrutinib,
• Acalabrutinib yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no tsum tsis pub noj acalabrutinib thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

Acalabrutinib yog siv los kho cov neeg mob mantle cell lymphoma (MCL; tus mob qog nqaij hlav sai sai uas pib hauv cov kab mob hauv lub nruab nrog cev) uas twb tau kho nrog tsawg kawg ib yam tshuaj kho mob. Nws kuj tseem siv ib leeg lossis nrog obinutuzumab (Gazyva) los kho tus mob lymphocytic rau cov leeg ntshav (CLL; ib hom mob cancer uas pib hauv cov qe ntshav dawb) thiab lymphocytic lymphoma me me (SLL: ib hom mob cancer uas pib hauv cov qe ntshav dawb) Cov. Acalabrutinib nyob hauv chav kawm ntawm cov tshuaj hu ua kinase inhibitors. Nws ua haujlwm los ntawm kev thaiv qhov kev txiav txim ntawm cov protein tsis txaus ntseeg uas ua teeb liab rau cov cell mob qog hlav. Qhov no yuav pab kom tsis txhob kis mob hlwb.

Acalabrutinib los ua tshuaj ntsiav los noj ntawm qhov ncauj. Nws feem ntau noj nrog lossis tsis noj zaub nyob hauv txhua 12 teev (ob zaug hauv ib hnub) kom ntev li ntev tau yog koj tus kws kho mob pom zoo kom koj tau txais kev kho mob. Siv acalabrutinib nyob ib ncig ntawm tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj acalabrutinib raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Nqos cov tsiav tshuaj tag nrho nrog ib khob dej; tsis txhob qhib, chew, lossis ua txhaum lawv.

Koj tus kws kho mob tuaj yeem kho koj ib ntus lossis ib ntus lossis txo koj cov tshuaj acalabrutinib nyob ntawm cov kev mob tshwm sim uas koj ntsib. Nco ntsoov nrog koj tus kws kho mob tham txog koj lub siab xav li cas thaum kho koj tus mob. Tsis txhob tsum noj acalabrutinib yam tsis tham nrog koj tus kws kho mob.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj acalabrutinib,

• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau acalabrutinib, lwm yam tshuaj noj, lossis lwm yam tshuaj hauv acalabrutinib tsiav tshuaj. Nug koj tus kws muag tshuaj lossis tshawb xyuas Cov Ntawv Qhia Cov Neeg Mob rau cov npe ntawm cov khoom siv.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj uas siv tshuaj thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog kev siv tshuaj anticoagulant ('ntshav cov ntshav') xws li warfarin (Coumadin); tshuaj antiplatelet ('cov ntshav ua kom ntshav') xws li tshuaj aspirin, cilostazol, clopidogrel (Plavix), dipyridamole (Persantine, hauv Aggrenox), prasugrel (Effient), ticagrelor (Brilinta), thiab ticlodipine; diltiazem (Cardizem, Cartia, Diltzac, lwm tus); erythromycin (E.E.S., Eryc, Erythrocin, lwm tus); fluconazole (Diflucan); itraconazole (Onmel, Sporanox); proton twj tso kua mis inhibitors xws li dexlansoprazole (Dexilant), esomeprazole (Nexium, hauv Vimovo), lansoprazole (Prevacid, hauv Prevpac), omeprazole (Prilosec, hauv Yosprala, Zegerid), pantoprazole (Protonix), thiab rabeprazole (Aciphex); thiab rifampin (Rifadin, Rimactane, hauv Rifater, Rifamate). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm yam tshuaj kuj tseem tuaj yeem cuam tshuam nrog acalabrutinib, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no.
• yog tias koj noj cimetidine (Tagamet), famotidine (Pepcid, hauv Vimxis), nizatidine (Axid), lossis ranitidine (Zantac) noj acalabrutinib tsawg kawg 2 teev ua ntej noj cov tshuaj no.
• yog tias koj noj tshuaj antacids (Maalox, Mylanta, Tums, lwm tus) noj acalabrutinib tsawg kawg 2 teev ua ntej lossis tom qab noj cov tshuaj no.
• qhia rau koj tus kws kho mob yog tias koj muaj mob voos lossis tau phais mob tsis ntev los no, lossis yog tias koj muaj lossis koj muaj kab mob siab nrog rau kab mob siab B, muaj teeb meem nrog koj lub plawv dhia, lossis muaj teeb meem los ntshav.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Koj yuav tsum tsis txhob cev xeeb tub thaum koj noj tshuaj acalabrutinib. Koj yuav tsum tsis txhob pib noj acalabrutinib kom txog rau thaum kev kuaj cev xeeb tub tau qhia tias koj tsis tau xeeb tub thiab koj yuav tsum siv kev tswj kom tsis txhob muaj menyuam kom tiv thaiv kev xeeb tub lub sijhawm kho thiab tsawg kawg 1 lub lis piam tom qab koj cov tshuaj zaum kawg. Acalabrutinib tuaj yeem tsim kev puas tsuaj rau koj tus menyuam hauv plab. Yog tias koj cev xeeb tub thaum noj acalabrutinib, hu rau koj tus kws kho mob tam sim ntawd.
• qhia rau koj tus kws kho mob yog tias koj pub mis niam rau menyuam. Koj tus kws kho mob yuav qhia koj kom tsis txhob pub mis niam rau lub sijhawm kho thiab 2 lub lis piam tom qab koj zaum kawg.
• yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws khomob lossis kws kho hniav tias koj noj acalabrutinib. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj acalabrutinib lub sijhawm ua ntej thiab tom qab phais lossis cov txheej txheem.
• npaj ua kom tsis txhob muaj qhov phom sij lossis tsis haum rau lub hnub ci thiab hnav khaub ncaws tiv thaiv, tsom iav, thiab tshuaj pleev thaiv hnub. Acalabrutinib yuav ua rau koj cov tawv nqaij ua rau muaj kev phom sij los ntawm lub hnub ci, thiab yuav ua rau koj muaj kev pheej hmoo ntawm kev tsim mob qog nqaij tawv.

Tham nrog koj tus kws kho mob txog kev noj txiv kab ntxwv qaub thiab haus kua txiv thaum lub sijhawm noj cov tshuaj no.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias ntau dua peb teev tau dhau los txij li lub koob tshuaj uas tsis nco qab lawm, hla ncua koob tshuaj uas tsis nco qab thiab ua ntxiv rau koj cov caij nyoog noj tshuaj tas li. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Acalabrutinib yuav ua rau muaj kev phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• mob taub hau
• xeev siab
• ntuav
• cem quav
• zawv plab
• mob plab
• ua pob
• qhov tawv nqaij doog me lossis liab lossis xim liab rau ntawm daim tawv nqaij
• mob pob qij txha lossis mob leeg
• nkees heev

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no tsum tsis pub noj acalabrutinib thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

• kub taub hau, mob caj pas, ua daus no, los yog lwm yam cim ntawm tus kab mob
• hnoos, txog siav, mob hauv siab thaum koj nqus lossis hnoos, kub cev
• lub plawv dhia ceev lossis tsis meej, hais lus zoo nkauj, hnov ​​lub ntsej muag lossis kiv taub hau, tsaus muag, ua pa ceev, mob hauv siab
• muaj ntshav txawv lossis doog ntshav lossis doog ntshav
• cov ntshav hauv koj cov quav lossis dub, tarry tso quav; liab los yog daj tso zis; ntuav ntshav lossis kas fes ntuav hauv av; hnoos tau ntshav
• zoo li kiv taub hau, qaug zog, los yog tsis meej pem; hloov hais lus; mob taub hau uas kav ntev

Acalabrutinib tuaj yeem ua kom koj txoj kev pheej hmoo ntawm kev tsim lwm yam mob qog nqaij hlav. Tham nrog koj tus kws kho mob txog kev pheej hmoo ntawm kev noj cov tshuaj no.

Acalabrutinib tuaj yeem ua lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws khomob yuav xaj qee yam kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau acalabrutinib.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Kub siab^®