Inotuzumab Ozogamicin Txhaj Tshuaj

Zoo Siab

• Ua ntej siv inotuzumab ozogamicin txhaj,
• Kev txhaj tshuaj Inotuzumab ozogamicin yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas tau teev tseg rau hauv cov CEEB TOOM TSEEM CEEB LOSSIS LI CAS, hu rau koj tus kws kho mob tam sis lossis tau txais kev kho mob kub ceev:

Kev txhaj tshuaj rau Inotuzumab ozogamicin tuaj yeem ua rau lub siab puas lossis ua rau lub siab puas, nrog rau cov kab mob hepatic veno-occlusive (VOD; thaiv cov hlab ntshav hauv lub siab). Qhia rau koj tus kws kho mob yog tias koj tau muaj lossis muaj kab mob siab lossis muaj mob qog nqaij hlav hauv lub cev (HSCT; cov txheej txheem uas qee cov ntshav tawm ntawm lub cev tawm thiab rov qab los rau hauv lub cev). Yog koj pom muaj cov tsos mob li hais hauv qab no, hu rau koj tus kws kho mob tam sim ntawd: ua rau lub cev hnyav sai, mob lossis o rau ntawm sab sauv sab hauv lub plab, qw nqaij tawv lossis qhov muag, xeev siab, ntuav, tso zis daj tsaus ntuj, lossis nkees heev.

Inotuzumab ozogamicin txhaj tshuaj tuaj yeem ua rau muaj kev pheej hmoo tuag, tsis yog vim rov qab mob leukemia, tom qab tau txais HSCT. Yog tias koj muaj cov tsos mob nram qab no tom qab HSCT thaum tau txhaj tshuaj inotuzumab ozogamicin, hu rau koj tus kws kho mob tam sim ntawd: kub taub hau, hnoos, mob caj pas, ua daus no, lossis lwm yam tsos mob; nce ceeb thawj sai, lossis mob lossis o rau ntawm sab sauv sab hauv lub plab.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj yam kev kuaj ua ntej, thaum, thiab tom qab koj txoj kev kho mob kuaj seb koj lub cev teb li cas rau inotuzumab ozogamicin.

Kev txhaj tshuaj Inotuzumab ozogamicin yog siv los kho qee tus mob lymphoblastic leukemia (TXHUA; ib hom mob cancer uas pib hauv cov qe ntshav dawb) hauv cov neeg laus uas tsis tau txais kev kho mob cancer yav dhau los. Inotuzumab ozogamicin txhaj tshuaj yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua monoclonal antibodies. Nws ua haujlwm los ntawm kev ua kom muaj zog tiv thaiv kab mob ua rau tua cov kab mob qog ntshav.

Tus kws kho mob lossis tus nais maum hauv tsev kho mob lossis chaw kho mob ua rau Inotuzumab ozogamicin txhaj los ua hmoov tuaj yeem sib xyaw nrog cov kua uas yuav txhaj tshuaj rau hauv ntshav (los ntshav). Feem ntau nws tau txhaj rau hnub 1, 8, thiab 15 ntawm 3- rau 4-lub hlis. Lub voj voog yuav rov ua dua txhua 4 asthiv raws li koj tus kws kho mob pom zoo. Lub sijhawm koj kho yog nyob ntawm seb koj lub cev teb li cas rau cov tshuaj thiab cov kev mob tshwm sim uas koj muaj.

Koj tus kws kho mob yuav xav cuam tshuam lossis tso tseg kev kho mob, txo qis koj cov tshuaj, lossis kho koj nrog cov tshuaj ntxiv, nyob ntawm koj cov lus teb rau inotuzumab ozogamicin thiab cov kev mob tshwm sim uas koj tau ntsib dua. Koj yuav tau txais qee yam tshuaj los pab tiv thaiv kev fab tshuaj ua ntej koj tau txais txhua koob tshuaj inotuzumab ozogamicin. Qhia rau koj tus kws kho mob lossis tus neeg saib xyuas neeg mob yog tias koj pom muaj cov tsos mob hauv qab no thaum thiab tsawg kawg ib teev tom qab kawg ntawm kev coj khaub ncaws: ua npaws, ua daus no, tawm pob, ua pa luv, lossis ua pa nyuaj. Tham nrog koj tus kws kho mob hais txog saib koj nyob li cas thaum kho thiab tom qab kho koj.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej siv inotuzumab ozogamicin txhaj,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau inotuzumab ozogamicin, lwm yam tshuaj, lossis lwm yam tshuaj hauv inotuzumab ozogamicin txhaj. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txhua yam ntawm cov hauv qab no: amiodarone (Pacerone, Nexterone); chloroquine (Aralen); clarithromycin (Biaxin, hauv Prevpac); disopyramide (Norpace); erythromycin (E.E.S., E-Mycin, P.C.E, lwm tus); haloperidol; tshuaj txiav yeeb (Dolophine, Methadose); nefazodone; pimozide (Orap); procainamide; quinidine (hauv Nuedexta); sotalol (Betapace, Betapace AF, Sorine); thiab thioridazine. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm yam tshuaj kuj tseem tuaj yeem cuam tshuam nrog inotuzumab ozogamicin, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias cov uas tsis tshwm hauv cov npe no.
• qhia rau koj tus kws kho mob yog tias koj lossis ib tus neeg hauv koj tsev neeg tau muaj lossis muaj lub sijhawm QT ntev (qhov teeb meem tsis tshua muaj lub plawv uas yuav ua rau lub plawv dhia tsis xwm yeem, tsaus muag, lossis cia li tuag kiag). Tsis tas li, qhia koj tus kws kho mob yog tias koj tau lossis muaj ib txwm muaj ntau yam potassium lossis magnesium nyob hauv koj cov ntshav lossis lub raum.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Yog tias koj yog poj niam, koj yuav tsum tsis txhob cev xeeb tub thaum koj tau txais tshuaj inotuzumab ozogamicin thiab tsawg kawg 8 lub hlis tom qab koj koob kawg. Tham nrog koj tus kws kho mob txog kev tiv thaiv kev xeeb tub uas yuav ua haujlwm rau koj. Yog tias koj yog txiv neej, koj thiab koj tus poj niam tus khub yuav tsum siv tshuaj tswj kom tsis txhob muaj menyuam thaum lub sijhawm kho thiab tseem siv tshuaj tiv thaiv me nyuam tsawg kawg yog 5 hlis tom qab koj qhov tshuaj kawg. Yog tias koj lossis koj tus khub ua cev xeeb tub thaum tau txais inotuzumab ozogamicin, hu rau koj tus kws kho mob. Inotuzumab ozogamicin tuaj yeem cuam tshuam cov menyuam hauv plab.
• qhia rau koj tus kws kho mob yog tias koj pub mis niam rau menyuam. Koj tus kws kho mob yuav qhia koj kom tsis txhob pub mis niam rau lub sijhawm kho nrog inotuzumab ozogamicin txhaj thiab tsawg kawg 2 hlis tom qab koj cov tshuaj zaum kawg.
• koj yuav tsum paub tias cov tshuaj no tuaj yeem txo qis kev muaj menyuam hauv txivneej thiab pojniam. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev tau txais inotuzumab ozogamicin.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Kev txhaj tshuaj Inotuzumab ozogamicin yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• kiv taub hau
• lub teeb ci ntsa iab

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas tau teev tseg rau hauv cov CEEB TOOM TSEEM CEEB LOSSIS LI CAS, hu rau koj tus kws kho mob tam sis lossis tau txais kev kho mob kub ceev:

• kub taub hau, ua daus no, hnoos, lossis lwm yam cim ntawm tus kab mob
• ntshav txawv lossis doog ntshav
• dub thiab tarry quav
• liab ntshav hauv cov quav
• daj ntseg tawv nqaij
• nkees

Kev txhaj tshuaj Inotuzumab ozogamicin tuaj yeem tsim kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum tau txais cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Nug koj tus kws muag tshuaj yog tias koj muaj lus dab tsi txog kev txhaj tshuaj inotuzumab ozogamicin.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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