Evolocumab Txhaj Tshuaj

Zoo Siab

• Ua ntej siv cov tshuaj txhaj tshuaj evolocumab,
• Evolocumab txhaj tshuaj tuaj yeem ua rau phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, tsum tsis txhob siv tshuaj hno thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

Kev txhaj tshuaj Evolocumab yog siv los txo qis kev pheej hmoo ntawm mob hlab ntsha tawg lossis plawv nres lossis xav tau kev phais mob ntawm cov hlab ntsha o bypass (CABG) rau cov neeg muaj mob plawv. Evolocumab txhaj tshuaj kuj tseem siv nrog rau kev noj zaub mov noj ib leeg los yog sib xyaw nrog lwm cov tshuaj roj ntshav qis xws li HMG-CoA reductase inhibitors (statins) lossis ezetimbe (Zetia) kom txo qis cov roj lipoprotein (LDL) roj (cov cholesterol) ') nyob rau hauv cov ntshav, suav nrog cov neeg uas muaj kev mob ntshav siab (heFozygous hypercholesterolemia (HeFH; qhov mob uas muaj los ntawm cov roj (cholesterol) tsis tuaj yeem tawm ntawm lub cev ib txwm)). Nws kuj tseem siv nrog rau kev hloov kev noj zaub mov noj thiab lwm yam kev kho mob los txo qis cov lipoprotein (LDL) cov roj (cholesterol) tsis zoo hauv cov ntshav hauv cov neeg uas muaj homozygous tsev neeg hypercholesterolemia (HoFH; cov mob uas muaj roj ntsha uas tsis tuaj yeem muaj tshem tawm ntawm lub cev ib txwm). Evolocumab txhaj tshuaj yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua proprotein convertase subtilisin kexin hom 9 (PCSK9) inhibitor monoclonal antibody. Nws ua haujlwm los ntawm kev thaiv cov khoom tsim cov roj cholesterol LDL hauv lub cev kom txo qis cov roj cholesterol uas tuaj yeem ua rau cov phab ntsa ntawm cov hlab ntsha thiab thaiv cov ntshav txaus rau lub plawv, hlwb, thiab lwm qhov hauv lub cev.

Kev txuam nrog cov roj (cholesterol) nyob rau phab ntsa ntawm koj cov hlab ntsha (cov txheej txheem hu ua atherosclerosis) txo cov ntshav txaus thiab vim li no, cov pa oxygen rau koj lub plawv, lub hlwb, thiab lwm qhov hauv koj lub cev.

Evolocumab txhaj tshuaj tuaj ua kev daws teeb meem (ua kua) hauv cov tshuaj tiv thaiv kab mob ua ntej, tus kws kho mob ua ntej, thiab hauv lub cev tiv thaiv kab mob nrog lub ntsej muag ua kom txhaj tshuaj subcutaneously (tsuas yog hauv qab daim tawv nqaij). Thaum hno tshuaj evolocumab yog siv kho HeFH lossis kab mob plawv lossis txo qis kev pheej hmoo ntawm mob hlab ntsha tawg, mob plawv, thiab mob hlab ntshav hla kev phais, feem ntau nws tau txhaj rau txhua 2 asthiv lossis ib hlis ib zaug. Thaum hno tshuaj evolocumab yog siv los kho HoFH, feem ntau nws txhaj ib hlis ib zaug. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Siv evolocumab txhaj tshuaj raws nraim li qhia. Tsis txhob siv ntau dua lossis tsawg dua ntawm cov tshuaj no lossis siv ntau dua lossis siv sijhawm ntev dua li koj tus kws khomob tau qhia.

Yog tias koj tab tom siv cov tshuaj evolocumab ib hlis ib zaug (420 mg koob tshuaj), hno nws ib zaug dhau 9 feeb nrog lub cev ntawm sab hauv thiab lub taub ntim tshuaj ua ntej rau txhua txoj kev txhaj tshuaj lossis hno 3 cais ib zaug ntxiv tom qab sib nrug hauv 30 feeb, siv ib qho tshuaj ntxiv koob txhaj tshuaj los yog npaj muab tshuaj rau ib qho tshuaj txhaj.

Kev txhaj tshuaj Evolocumab pab tswj cov qib roj cholesterol thiab txo kev pheej hmoo ntawm mob hlab ntsha tawg, mob plawv, lossis mob hlab ntsha o hla kev phais, tab sis nws tsis kho cov kev mob no lossis tshem tawm cov kev pheej hmoo no. Siv cov kev txhaj tshuaj evolocumab txuas ntxiv txawm tias koj xis nyob. Tsis txhob tsum tsis txhob siv cov tshuaj hnoos qhuav tsis tas tham nrog koj tus kws kho mob.

Evolocumab txhaj tshuaj tuaj nrog ib tus kws kho mob ua ntej, siv tshuaj txhaj, thiab hauv ib qho tshuaj txau nrog cov roj ntim tshuaj uas muaj tshuaj txaus rau ib koob. Ib txwm hno cov tshuaj evolocumab hauv nws tus kheej tshwj xeeb autoinjector, koob txhaj tshuaj, lossis infusor nrog lub taub hau ntim hauv thawv; tsis txhob sib tov nrog lwm cov tshuaj. Cuam tshuam ntawm cov koob uas siv, koob txhaj tshuaj, thiab cov cuab yeej hauv lub thawv uas muaj tshuaj tiv thaiv. Tham nrog koj tus kws kho mob lossis kws muag tshuaj txog yuav ua li cas pov tseg cov thawv ntim tshuaj tiv thaiv.

Koj tuaj yeem siv cov tshuaj evolocumab txhaj tshuaj nyob hauv qab daim tawv nqaij ntawm koj sab ncej puab lossis thaj tsam hauv plab, tshwj tsis yog 2-nti thaj tsam ib ncig koj lub pij ntaws (lub plab hauv plab). Yog tias lwm tus yuav txhaj cov tshuaj rau koj, tus neeg ntawd tuaj yeem txhaj nws rau hauv koj sab caj npab. Siv qhov chaw sib txawv rau txhua qhov kev txhaj tshuaj. Tsis txhob txhaj cov tshuaj evolocumab mus rau hauv qhov chaw uas yog kev sib tw, nqaij tawv, liab, lossis tawv. Tsis tas li, tsis txhob txhaj rau thaj chaw uas muaj nti lossis ncab.

Ua tib zoo nyeem cov chaw tsim tshuaj cov lus qhia rau kev siv uas tuaj nrog cov tshuaj. Cov lus qhia no piav qhia txog yuav ua li cas txhaj tshuaj hnoos qhuav ntawm kev txhaj tshuaj evolocumab. Nco ntsoov nug koj tus kws muag tshuaj lossis kws kho mob yog tias koj lossis tus neeg uas yuav tau txhaj tshuaj muaj lus nug txog yuav siv cov tshuaj no li cas. Saib Cov lus qhia rau Siv los ntawm cov chaw tsim khoom ntawm https://bit.ly/3jTG7cx.

Tshem cov koob txhaj tshuaj los yog tshuaj pleev rau hauv lub tub yees thiab muab nws rau hauv chav sov li 30 feeb ua ntej siv. Tshem lub khaub zig nrog lub thawv ntawv ua los ntawm tub yees ntawm lub tub yees thiab cia nws kom sov rau chav sov li 45 feeb ua ntej siv nws. Tsis txhob sov txoj kev txhaj tshuaj rau cov dej kub, microwave, lossis muab tso rau hauv tshav ntuj.

Ua ntej koj siv kev txhaj tshuaj evolocumab, saib txoj kev daws teeb meem kom zoo. Cov tshuaj yuav tsum ua kom pom tseeb kom daj ntseg daj thiab dawb ntawm ntab tawm. Tsis txhob co cov tshuaj txhaj uas twb npaj lawm, ua ntej muab tshuaj rau hauv lub cev, lossis lub taub txau nrog lub taub hau uas ntim cov tshuaj ua kom tawg.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej siv cov tshuaj txhaj tshuaj evolocumab,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau kev txhaj tshuaj tiv thaiv kab mob, lwm yam tshuaj noj, hnab looj, roj hmab, lossis ib qho twg hauv cov tshuaj txhaj evolocumab. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia rau koj tus kws kho mob yog tias koj tau lossis muaj ib yam muaj mob dab tsi.
• qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj xeeb tub thaum siv cov tshuaj hnoos qhuav, hu koj tus kws kho mob.

Noj zaub mov tsis muaj roj thiab roj tsawg. Nco ntsoov ua raws li tag nrho cov kev tawm dag zog thiab kev noj haus pom zoo ua los ntawm koj tus kws kho mob lossis tus kws qhia noj zaub mov. Koj tseem tuaj yeem mus saib tau Lub Txheej Txheem Kev Kawm Cholesterol (NCEP) lub vev xaib kom paub cov ntaub ntawv qhia txog zaub mov ntxiv ntawm: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Yog tias koj siv cov tshuaj evolocumab txhaj tshuaj txhua 2 lub lis piam thiab yog tias nws tsis dhau 7 hnub txij li hnub koj tsis nco qab teem sijhawm, hno nws sai li sai tau thaum koj nco qab nws thiab rov qab noj tshuaj ntxiv. Txawm li cas los xij, yog tias muaj ntau dua 7 hnub los ntawm koj cov tshuaj tsis nco qab, hla nws thiab txuas ntxiv koj cov caij nyoog noj tshuaj tas li. Tsis txhob txhaj ob koob tshuaj ntxiv los ua qhov koob tshuaj uas ploj lawm. Hu rau koj tus kws kho mob yog tias koj tsis nco qab noj tshuaj thiab muaj lus nug txog yuav ua li cas.

Yog tias koj siv cov tshuaj hnoos qhuav zuj zus ib hlis ib zaug thiab yog tias nws tsis dhau 7 hnub txij li hnub koj tsis nco qab noj lawm, hno nws sai li sai tau thaum koj nco qab nws thiab rov qab noj tshuaj ntxiv. Txawm li cas los xij, yog tias koj tswj cov tshuaj evolocumab txhaj ib hlis ib zaug thiab muaj ntau dua 7 hnub los ntawm koj cov koob tshuaj uas koj tsis nco qab, hno nws tam sim ntawd thiab pib lub sijhawm noj tshuaj tshiab raws li hnub no. Tsis txhob txhaj ob koob tshuaj ntxiv los ua qhov koob tshuaj uas ploj lawm. Hu rau koj tus kws kho mob yog tias koj tsis nco qab noj tshuaj thiab muaj lus nug txog yuav ua li cas.

Evolocumab txhaj tshuaj tuaj yeem ua rau phiv. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• liab, khaus, o, mob, lossis mob rau ntawm qhov chaw txhaj tshuaj
• Cov tsos mob khaub thuas zoo li mob khaub thuas, los ntswg, mob caj pas, ua npaws, lossis ua daus no
• mob los sis kub thaum tso zis
• leeg los yog mob nraub qaum
• kiv taub hau
• mob plab

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, tsum tsis txhob siv tshuaj hno thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

• khaus
• ua pob
• khaus
• ua pa nyuaj lossis nqos
• o ntawm lub ntsej muag, lub caj pas, tus nplaig, daim di ncauj, thiab qhov muag

Evolocumab txhaj tshuaj tuaj yeem ua lwm cov phiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum siv cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Muab cia rau hauv tub yees, tab sis tsis txhob muab cia kom khov. Tsis txhob tso cov tshuaj evolocumab sab nraum lub tub yees rau ntau tshaj 30 hnub. Kev txhaj tshuaj Evolocumab tuaj yeem khaws cia rau ntawm chav tsev qhov kub li qub hauv cov thawv thawj zaug txog 30 hnub. Khaws cov tshuaj evolocumab txav deb ntawm lub teeb ncaj qha.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau txoj kev txhaj tshuaj evolocumab.

Nug koj tus kws muag tshuaj yog tias koj muaj lus dab tsi txog kev txhaj tshuaj evolocumab.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Ntsuas Rov^®