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Isavuconazole: primary anti-fungal prophylaxis in AML and MDS
Daim Duab: Isavuconazole: primary anti-fungal prophylaxis in AML and MDS

Zoo Siab

Isavuconazonium yog siv los kho cov muaj mob fungal ntau yam xws li tus kab mob sib kis tau zoo (ib tug kab mob fungal uas pib hauv lub ntsws thiab kis tau los ntawm cov hlab ntshav mus rau lwm yam hauv nrog cev) thiab ua rau cov leeg muaj hnoos qeev (mob fungal uas feem ntau pib ua mob rau lub ntsws, lub hlwb, lossis ntsws). Isavuconazonium nyob hauv chav kawm ntawm cov tshuaj hu ua azole antifungals. Nws ua haujlwm los ntawm kev ua kom qeeb ntawm kev loj hlob ntawm cov fungi uas ua rau kis kab mob.

Isavuconazonium los ua tshuaj ntsiav los noj ntawm qhov ncauj. Nws feem ntau yog noj nrog lossis tsis tau noj zaub mov txhua 8 teev rau thawj 6 koob thiab tom qab ntawd ib hnub. Siv isavuconazonium nyob ib ncig ntawm tib lub sijhawm (s) txhua txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj isavuconazonium raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Nqos cov tsiav tshuaj tag nrho; tsis txhob qhib, zom, yaj, lossis zuaj lawv.

Lub sijhawm koj kho yog nyob ntawm koj kev noj qab haus huv, hom kev kis koj muaj, thiab koj teb tau zoo npaum li cas rau cov tshuaj. Txuas mus noj isavuconazonium txawm hais tias koj tus kheej zoo. Tsis txhob tsum noj isavuconazonium yam tsis tham nrog koj tus kws kho mob.


Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj isavuconazonium,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau isavuconazonium, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, lwm yam tshuaj noj, lossis ib yam ntawm cov khoom xyaw hauv isavuconazonium tsiav tshuaj. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
  • qhia rau koj tus kws kho mob yog tias koj noj carbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, hauv Kaletra), lossis St. John's wort. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj isavuconazonium yog tias koj noj ib lossis ntau dua ntawm cov tshuaj no.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib yam ntawm cov hauv qab no: atorvastatin (Lipitor), bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban), cyclosporine (Gengraf, Neoral, Sandimmune), digoxin (Digitek, Lanoxicaps, Lanoxin), midazolam, mycophenolate mofetil (Cell ), sirolimus (Rapamune), lossis tacrolimus (Prograf). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm yam tshuaj kuj tuaj yeem cuam tshuam nrog isavuconazonium, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no.
  • qhia rau koj tus kws kho mob yog tias koj lossis ib tus neeg hauv koj tsev neeg muaj lossis muaj QT tas li sijhawm luv (mob uas ua rau lub plawv dhia tsis xwm yeem, kiv taub hau, tsaus muag, lossis cia li tuag kiag). Koj tus kws kho mob yuav qhia koj kom tsis txhob noj isavuconazonium.
  • qhia rau koj tus kws kho mob yog tias koj muaj lossis tau muaj teeb meem plawv lossis mob siab ua ntej.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj isavuconazonium, hu rau koj tus kws kho mob.

Tham nrog koj tus kws kho mob txog kev noj txiv kab ntxwv qaub thiab haus kua txiv thaum lub sijhawm noj cov tshuaj no.


Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws. Txawm li cas los xij, yog tias nws yuav luag txog rau koob tshuaj txuas ntxiv, hla cov koob tshuaj uas tsis nco qab noj thiab txuas ntxiv koj lub sijhawm noj tshuaj kom tsis tu ncua. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Isavuconazonium yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • zawv plab
  • cem quav
  • mob taub hau
  • rov qab mob
  • hnoos
  • teeb meem tsis tsaug zog los yog pw tsaug zog
  • ntxhov siab
  • ntxhov siab
  • tsis meej pem
  • tsis qab los

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, hu rau koj tus kws kho mob sai lossis tau txais kev kho mob kub ceev:

  • khaus
  • ua pob
  • khaus
  • tev lossis tawv nqaij ntawm daim tawv nqaij
  • xeev siab
  • ntuav
  • daj ntawm daim tawv nqaij lossis qhov muag
  • nkees heev
  • cov tsos mob khaub thuas zoo li
  • mob leeg, cramps, lossis qaug zog
  • lub plawv dhia tsis xwm yeem
  • o ntawm tes, taw, caj npab lossis ceg
  • ua pa nyuaj lossis nqos

Isavuconazonium tuaj yeem ua rau lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.


Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Isavuconazonium los hauv blister ntim thiab txhua qhov chaw hlwv muaj ob lub hnab ris. Cov hnab tshos sab laug muaj qhov desiccant (pob ntawv me me uas muaj cov khoom uas nqus cov dej noo kom ua rau cov tshuaj kom qhuav) thiab lub hnab tshos sab xis muaj cov tshuaj. Tsuas yog qhib lub isavuconazonium hnab tshos thiab tawm rau desiccant hauv lub ntim. Tsis txhob tshem tawm isavuconazonium los ntawm cov khoom ntim thawj zaug kom txog thaum koj npaj siab yuav noj koj cov tshuaj. Tsis txhob tso isavuconazonium hauv cov thawv tshuaj lossis cov koomhaum hauv ncoo. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

  • mob taub hau
  • kiv taub hau
  • mob, kub hnyiab, lossis mob nyhav rau ntawm txhais tes lossis taw
  • tsaug zog
  • teeb meem kev tsom mus
  • hloov nyob rau hauv kev nkag siab ntawm saj
  • qhov ncauj qhuav
  • loog hauv lub qhov ncauj
  • zawv plab
  • ntuav
  • dheev sai sai ntawm lub ntsej muag, caj dab, lossis hauv siab
  • ntxhov siab
  • nyob tsis tswm
  • npuag los yog lub plawv dhia ceev
  • rhiab ntawm lub qhov muag teeb
  • mob tej pob txha

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee qhov kuaj sim kuaj koj lub cev cov lus teb rau isavuconazonium.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

  • Cresemba®
Kawg Siv - 03/15/2017

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