Brentuximab Vedotin Txhaj Tshuaj

Zoo Siab

• Kev txhaj tshuaj Brentuximab vedotin yog siv
• Ua ntej tau txais kev txhaj tshuaj brentuximab vedotin,
• Kev txhaj tshuaj Brentuximab vedotin yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:
• Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

Tau txais kev txhaj tshuaj brentuximab vedotin tuaj yeem ua rau muaj kev pheej hmoo ntau ntxiv uas koj yuav tsim kho ntau yam mob hlwb (PML; ib qho kev kis mob hlwb tsawg kawg uas tsis tuaj yeem kho, tiv thaiv lossis kho thiab uas feem ntau ua rau tuag lossis mob xiam oob qhab loj). Qhia rau koj tus kws kho mob yog tias koj tau lossis muaj ib yam mob uas cuam tshuam rau koj lub cev. Qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj noj tshuaj uas siv tshuaj tiv thaiv kab mob. Yog tias koj muaj cov tsos mob nram qab no, tsum tsis txhob txhaj tshuaj brentuximab vedotin thiab hu rau koj tus kws kho mob tam sim ntawd: tsis muaj zog lossis tsis muaj zog ntawm ib sab ntawm lub cev; taug kev nyuaj; kev koom ua ke tsis tau; mob taub hau; tsis meej pem; nyuaj xav kom meej meej; nco ploj; kev hloov pauv hauv kev xav lossis ib txwm coj tus cwj pwm; nyuaj hais lus; lossis kev pom kev hloov.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj kom kuaj xyuas koj lub cev cov lus teb rau txhaj tshuaj brentuximab vedotin.

Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev txhaj tshuaj brentuximab vedotin.

Kev txhaj tshuaj Brentuximab vedotin yog siv

• ua ke nrog lwm cov tshuaj kho mob los kho Hodgkin's lymphoma (Hodgkin's disease) hauv cov uas tsis tau txais kev kho mob yav tas los,
• los kho Hodgkin's lymphoma hauv cov neeg muaj kev pheej hmoo rau lawv tus kab mob tsis zoo los yog rov qab los tom qab hloov qia ua pob (hloov txheej txheem uas hloov cov hlwb pob txha uas muaj mob hlwb pob txha zoo),
• los kho Hodgkin's lymphoma rau cov uas tsis teb rau qog cell hloov (tus txheej txheem los hloov cov hlwb pob txha uas muaj mob nrog lub hlwb pob txha zoo) lossis tsawg kawg ob lub sijhawm kev kho mob,
• ua ke nrog lwm txoj kev siv tshuaj kho mob los kho tus mob qog nqaij hlav loj hauv lub cev (sALCL; ib hom tsis yog Hodgkin lymphoma) thiab lwm yam mob uas tsis tseem ceeb rau T-cell lymphomas (PTCL; ib hom tsis yog Hodgkin lymphoma) hauv cov uas tsis tau muaj dua los tau txais kev kho mob,
• txhawm rau kho cov kab mob sALCL hauv cov neeg uas tsis teb rau lwm lub sijhawm kev kho mob tshuaj,
• los kho qee yam ntawm thawj qhov kev txiav txov txiav pob zeb loj loj ua qog nqaij hlav loj (pcALCL; ib hom tsis yog Hodgkin's lymphoma) hauv cov neeg uas tau txais lwm yam kev kho mob.

Kev txhaj tshuaj Brentuximab vedotin yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua tshuaj tiv thaiv kabmob-tshuaj sib txuas. Nws ua haujlwm los ntawm kev tua cov qog nqaij hlav cancer.

Tus kws kho mob lossis tus nais maum hauv chaw kho mob lossis tsev kho mob tau txhaj nrog Brentuximab vedotin txhaj tshuaj ua cov hmoov ua kom sib xyaw nrog cov kua thiab txhaj tshuaj li 30 feeb plhaw (rau hauv txoj leeg ntshav) los ntawm kws kho mob lossis kws kho mob hauv chaw kho mob lossis tsev kho mob. Thaum brentuximab vedotin tau txais los kho Hodgkin's lymphoma, sALCL, lossis PTCL, feem ntau yog txhaj ib zaug nyob rau txhua 3 asthiv ntev npaum li koj tus kws kho mob pom zoo kom koj tau txais kev kho mob. Thaum brentuximab vedotin siv nrog kev kho mob tshuaj los kho Hodgkin lymphoma ua thawj txoj kev kho mob, feem ntau yog txhaj ib zaug txhua 2 lub lis piam ntev npaum li koj tus kws kho mob pom zoo kom koj tau txais kev kho mob.

Kev txhaj tshuaj Brentuximab vedotin tuaj yeem ua rau muaj kev tsis haum tshuaj, uas feem ntau tshwm sim thaum lub sijhawm infusion ntawm kev noj tshuaj lossis hauv 24 teev tom qab tau txais koob tshuaj. Koj tuaj yeem tau txais qee yam tshuaj ua ntej koj qhov infusion los tiv thaiv kev ua xua yog tias koj muaj qhov tsis haum nrog kev kho yav dhau los. Koj tus kws kho mob yuav saib xyuas koj kom zoo thaum koj tau txais brentuximab vedotin. Yog koj muaj cov tsos mob li hais no, qhia rau koj tus kws kho mob tam sim ntawd: ua npaws, ua daus no, tawm pob, khaus, khaus, lossis ua pa nyuaj.

Koj tus kws kho mob yuav tsum ncua koj txoj kev kho mob, kho koj qhov kev noj tshuaj, lossis txiav koj txoj kev kho mob yog tias koj muaj tej kev mob tshwm sim. Nco ntsoov qhia koj tus kws kho mob seb koj xav li cas thaum kho nrog brentuximab vedotin txhaj.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej tau txais kev txhaj tshuaj brentuximab vedotin,

• qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj muaj kev fab tshuaj rau brentuximab vedotin, lwm yam tshuaj, lossis lwm yam tshuaj hauv brentuximab vedotin txhaj. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob yog tias koj tau txais bleomycin. Koj tus kws kho mob yuav qhia koj kom tsis txhob siv tshuaj brentuximab vedotin yog tias koj tau txais cov tshuaj no.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: clarithromycin (Biaxin, hauv PrevPac), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole, nefazodone, nelfinavir (Viracept), rifampin (Rifadin, Rimactane, hauv Rifamate, thiab hauv Rater) ritonavir (Norvir, hauv Kaletra). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
• qhia rau koj tus kws kho mob yog tias koj muaj lossis tau muaj mob siab lossis mob raum.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Yog tias koj yog tus poj niam uas tuaj yeem cev xeeb tub, koj yuav tsum kuaj cev xeeb tub ua ntej pib kev kho mob thiab siv tshuaj tiv thaiv kom tsis muaj menyuam thaum lub sijhawm kho thiab 6 lub hlis tom qab koj qhov tshuaj kawg. Yog tias koj yog txiv neej nrog tus poj niam koom tes uas cev xeeb tub los yog cev xeeb tub, koj yuav tsum siv tshuaj tiv thaiv kom zoo thaum lub sijhawm kho thiab 6 lub hlis tom qab koj qhov tshuaj kawg. Tham nrog koj tus kws kho mob txog kev tswj tsis pub muaj menyuam uas koj tuaj yeem siv. Yog tias koj lossis koj tus khub xeeb tub thaum tau txais kev txhaj tshuaj brentuximab vedotin, hu rau koj tus kws kho mob tam sim ntawd. Kev txhaj tshuaj Brentuximab vedotin tuaj yeem tsim kev puas tsuaj rau tus menyuam hauv plab.
• qhia rau koj tus kws kho mob yog tias koj pub mis niam rau menyuam. Koj yuav tsum tsis txhob noj niam mis thaum koj tseem tab tom txhaj tshuaj brentuximab vedotin.
• koj yuav tsum paub tias cov tshuaj no tuaj yeem txo qis kev muaj menyuam hauv cov txiv neej. Tham nrog koj tus kws kho mob txog cov kev pheej hmoo ntawm kev txhaj tshuaj brentuximab vedotin.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Kev txhaj tshuaj Brentuximab vedotin yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• cem quav
• qhov ncauj tawm
• tsis qab los
• poob phaus
• nkees nkees
• kiv taub hau
• tsis muaj zog
• teeb meem tsis tsaug zog los yog pw tsaug zog
• ntxhov siab
• daim tawv nqaij qhuav
• plaub hau poob
• tsaus ntuj tawm hws
• txha, pob txha, leeg, nraub qaum, caj npab, lossis mob ceg
• mob leeg pob txha

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

• ntshav txawv lossis doog ntshav
• loog, mob, lossis tingling hauv tes, caj npab, txhais ceg, lossis ceg
• leeg tsis muaj zog
• tev lossis tawv nqaij ntawm daim tawv nqaij
• khaus
• ua pob
• khaus
• xeev siab
• ntuav
• zawv plab
• hnoos lossis txog siav
• tsis tso zis tsawg
• o ntawm tes, taw, pob taws, lossis ceg qis
• nyuaj, mob, lossis tso zis heev
• kub taub hau, ua daus no, hnoos, lossis lwm yam cim ntawm tus kab mob
• kev mob tsis tu ncua uas pib hauv plab thaj chaw tab sis tuaj yeem kis rau sab nraub qaum
• daj ntseg tawv nqaij
• daj ntawm daim tawv nqaij lossis qhov muag
• mob los yog tsis xis nyob sab xis lub plab
• tsaus zis
• av nplaum-xim tso quav
• mob plab
• ntshav txawv lossis doog ntshav
• dub thiab tarry quav
• liab ntshav hauv cov quav

Kev txhaj tshuaj Brentuximab vedotin tuaj yeem ua rau lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum tau txais cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

• kub taub hau, ua daus no, hnoos, lossis lwm yam cim ntawm tus kab mob

Nug koj tus kws muag tshuaj yog tias koj muaj lus dab tsi txog kev txhaj tshuaj brentuximab vedotin.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Xauj Lauj^®