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Taking a Closer Look at Benefits and Risks of Rivaroxaban
Daim Duab: Taking a Closer Look at Benefits and Risks of Rivaroxaban

Zoo Siab

Yog tias koj muaj mob atrial fibrillation (ib qho mob uas lub plawv dhia tsis xwm yeem, ua rau muaj qhov txhaws ntau ntxiv hauv lub cev, thiab tej zaum ua rau mob stroke) thiab tab tom noj rivaroxaban los pab tiv thaiv mob ntshav txhaws lossis ntshav txhaws loj, koj muaj feem yuav muaj feem yuav muaj mob stroke tom qab koj tsum tsis noj yam tshuaj no. Tsis txhob tsum noj rivaroxaban tsis tas tham nrog koj tus kws kho mob. Txuas ntxiv rau noj rivaroxaban txawm hais tias koj xis neej. Nco ntsoov ntim cov tshuaj kom zoo ua ntej koj tawm ntawm cov tshuaj kom koj tsis txhob nco cov tshuaj ntawm rivaroxaban. Yog tias koj xav tsum tsis txhob noj rivaroxaban, koj tus kws kho mob tuaj yeem sau tshuaj rau lwm tus anticoagulant ('' thinner '') los pab tiv thaiv kom ntshav txhaws los ntawm kev tsim thiab ua rau koj mob stroke.

Yog tias koj muaj tus mob txha caj qaum los yog txha caj qaum txha nqaj qaum los yog txha caj qaum thaum noj ntshav "yuag ntshav dua tshiab" xws li rivaroxaban, koj yuav muaj feem yuav ua mob ntshav txhaws lossis nyob ib ncig ntawm koj tus txha nraub qaum uas tuaj yeem ua rau koj tuag tes tuag taw. Qhia rau koj tus kws kho mob yog tias koj muaj tus kab mob epidural catheter uas tseem tshuav nyob hauv koj lub cev lossis tau lossis muaj dua ib zaug mob txha caj qaum lossis txha caj qaum, mob txha caj qaum, lossis pob txha phais. Qhia rau koj tus kws kho mob thiab kws muag tshuaj yog tias koj noj tshuaj anagrelide (Agrylin); cov tshuaj aspirin thiab lwm cov tshuaj tiv thaiv nonsteroidal (NSAIDs) xws li ibuprofen (Advil, Motrin, lwm tus), indomethacin (Indocin, Tivorbex), ketoprofen, thiab naproxen (Aleve, Anaprox, lwm tus); cilostazol (Pletal); clopidogrel (Plavix); dipyridamole (Persantine); eptifibatide (Integrilin); heparin; prasugrel (Effient); xaiv serotonin-reuptake inhibitors xws li citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Selfemra), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), thiab sertraline (Zoloft); serotonin – norepinephrine reuptake inhibitors (SNRI) xws li desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), levomilnacipran (Fetzima), milnacipran (Savella), thiab venlafaxine (Effexor); ticagrelor (Brilinta); ticlopidine; tirofiban (Aggrastat), thiab warfarin (Coumadin, Jantoven). Yog tias koj muaj cov tsos mob nram qab no, hu rau koj tus kws kho mob tam sim ntawd: mob nraub qaum, mob leeg tsis muaj zog, loog lossis txhaws caj pas (tshwj xeeb hauv koj ob txhais ceg), plam tswj koj lub plab lossis zais zis, los yog tsis tuaj yeem txav koj ob txhais ceg.


Tham nrog koj tus kws kho mob txog kev pheej hmoo ntawm kev noj rivaroxaban.

Koj tus kws kho mob lossis kws muag tshuaj yuav muab daim ntawv qhia cov neeg mob rau koj (Siv Tshuaj Kho Mob) thaum koj pib kho rivaroxaban thiab txhua zaus koj rov ntim tshuaj. Nyeem cov ntaub ntawv kom zoo thiab nug koj tus kws kho mob lossis kws muag tshuaj yog tias koj muaj lus nug. Koj kuj tuaj yeem mus saib Food Food and Drug Administration (FDA) lub vev xaib (http://www.fda.gov/downloads/Drugs/DrugSafety/UCM280333.pdf) lossis lub chaw tsim tshuaj paus lub vev xaib kom tau txais Kev Qhia Tshuaj.

Rivaroxaban yog siv los kho cov leeg ntshav khov (DVT; mob ntshav khov, feem ntau mob ceg) thiab mob ntsws ntsig (PE; ntshav tawm hauv lub ntsws). Rivaroxaban tuaj yeem txuas ntxiv kom tiv thaiv DVT thiab / lossis PE los ntawm kev rov tshwm sim dua tom qab kev kho mob thawj zaug tau ua tiav. Nws kuj tseem siv los pab tiv thaiv cov hlab ntsha tawg lossis ntshav khov rau cov neeg uas muaj atrial fibrillation (ib qho mob uas lub plawv dhia tsis xwm yeem, ua rau muaj qhov txhaws ntau ntxiv hauv lub cev, thiab tej zaum ua rau mob stroke) yam tsis muaj mob plawv. Rivaroxaban tuaj yeem txo qhov kev pheej hmoo ntawm DVT, uas tuaj yeem ua rau PE rau cov neeg uas muaj lub duav hloov lossis lub hauv caug hloov phais. Nws kuj tseem siv nrog rau cov tshuaj aspirin kom txo qis kev pheej hmoo ntawm lub plawv nres, mob hlab ntsha tawg, lossis tuag rau cov neeg muaj mob hlab ntsha ntsig (ua kom txoj hlab ntshav me txaus los ntshav) uas muab ntshav rau caj npab thiab ceg). Rivaroxaban yog nyob rau hauv chav kawm ntawm cov tshuaj hu ua factor Xa inhibitors. Nws ua haujlwm los ntawm kev muaj peev xwm txo cov ntshav khov hauv cov ntshav.


Rivaroxaban los ua ib ntsiav tshuaj noj ntawm qhov ncauj. Thaum rivaroxaban yog siv los kho kev kho mob DVT lossis PE, feem ntau nws noj nrog zaub mov ob zaug rau 21 hnub, tom qab ntawd ib hnub nrog zaub mov. Thaum rivaroxaban siv los tiv thaiv DVT lossis PE, feem ntau yog noj ib hnub ib zaug nrog lossis tsis muaj zaub mov tom qab tsawg kawg 6 lub hlis ntawm kev siv tshuaj anticoagulation (ntshav thinner). Thaum rivaroxaban siv los tiv thaiv tus mob stroke nyob rau hauv cov neeg uas lub plawv dhia tsis xwm yeem, feem ntau yog noj ib hnub ib zaug nrog noj hmo. Thaum rivaroxaban raug coj los tiv thaiv DVT thiab PE tom qab lub duav lossis hauv caug hloov phais, feem ntau yog noj nrog lossis tsis muaj zaub mov noj ib hnub ib zaug. Thawj koob yuav tsum tau noj tsawg kawg 6 mus rau 10 teev tom qab phais mob. Rivaroxaban feem ntau yog noj rau 35 hnub tom qab kev hloov lub ntsag thiab rau 12 hnub tom qab phais mob lub hauv caug. Thaum rivaroxaban noj nrog rau cov tshuaj aspirin rau cov neeg muaj mob rau cov hlab ntshav lossis hlab ntsha txhaws, feem ntau yog noj ob zaug ib hnub nrog lossis tsis noj mov. Noj rivaroxaban nyob ib ncig ntawm tib lub sijhawm txhua hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj rivaroxaban raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.


Yog tias koj tsis tuaj yeem nqos cov ntsiav tshuaj, koj tuaj yeem tsoo lawv thiab sib tov nrog txiv applesauce. Nqos cov dej qab zib tom qab koj npaj. Rivaroxaban tseem tuaj yeem muab rau hauv qee hom kev pub noj raj. Nug koj tus kws kho mob yog tias koj yuav tsum noj cov tshuaj no hauv koj txoj kev pub mis. Ua raws nraim li koj tus kws kho mob cov lus qhia.

Txuas ntxiv rau noj rivaroxaban txawm hais tias koj xis neej. Tsis txhob tsum noj rivaroxaban tsis tas tham nrog koj tus kws kho mob. Yog tias koj tsum tsis txhob noj rivaroxaban, koj qhov kev pheej hmoo ntawm kev mob ntshav txhaws tuaj ntxiv.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj rivaroxaban,

  • qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau rivaroxaban, lwm yam tshuaj noj, lossis lwm yam tshuaj hauv rivaroxaban ntsiav tshuaj. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
  • qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob sau tseg thiab cov tshuaj uas tsis yog kws kho mob, cov vitamins, thiab cov khoom noj zoo uas koj noj lossis npaj yuav noj. Nco ntsoov hais txog cov tshuaj teev tseg rau hauv seem tseem ceeb ceebtoom thiab ib qho twg ntawm cov hauv qab no: amiodarone (Pacerone), azithromycin (Zithromax), carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Tegretol-XR, Teril), clarithromycin (Biaxin, in Prevpac), conivaptan (Vaprisol), diltiazem (Cardizem, Dilacor, Tiazac), dronedarone (Multaq), erythromycin (EES, E-Mycin, Erythrocin), felodipine (Plendil), fluconazole (Diflucan), indinavir (Crixiv) Onmel, Sporanox), ketoconazole (Nizoral), lopinavir (hauv Kaletra), phenobarbital, phenytoin (Dilantin, Phenytek), quinidine, ranolazine (Ranexa), rifampin (Rifadin, hauv Rifamate, hauv Rifaterit, Rimactane), Kaletra), thiab verapamil (Calan, Verelan, hauv Tarka). Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv.
  • qhia koj tus kws kho mob tias yam tshuaj ntsuab koj noj, tshwj xeeb tshaj yog St. John wort.
  • qhia rau koj tus kws kho mob yog tias koj los ntshav hnyav heev hauv koj lub cev uas tsis tuaj yeem nres. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj rivaroxaban.
  • qhia rau koj tus kws kho mob yog tias koj tau muaj lub valve nyob hauv koj lub siab hloov lossis muaj lossis puas tau muaj teeb meem nrog cov ntshav txawv, ntshav tsis meej, lossis lub raum lossis mob siab.
  • qhia koj tus kws kho mob yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub mis niam. Yog tias koj cev xeeb tub thaum noj rivaroxaban, hu rau koj tus kws kho mob.
  • tham nrog koj tus kws kho mob txog cov kev pheej hmoo thiab cov txiaj ntsig ntawm kev noj rivaroxaban yog tias koj muaj hnub nyoog 75 xyoos lossis laus dua.
  • yog tias koj muaj kev phais, suav nrog kev phais hniav, qhia tus kws kho mob lossis kws kho hniav tias koj noj rivaroxaban.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Yog tias koj noj rivaroxaban ib hnub ib zaug, noj cov koob tshuaj uas ploj lawm thaum koj nco qab nws nyob rau hnub ntawd. Rov qab ntsuas koj cov tshuaj noj tas li rau hnub tom qab.

Yog tias koj noj rivaroxaban ib hnub ob zaug rau kev kho mob ntawm DVT lossis PE, noj cov tshuaj uas ploj lawm sai li sai tau thaum koj nco qab nws nyob rau hnub ntawd. Koj tuaj yeem noj 2 lub tshuaj tib lub sijhawm kom ua qhov kev ncua tsis tau. Rov qab ntsuas koj cov sij hawm noj tshuaj tas li rau hnub tom qab

Yog tias koj muaj CAD lossis PAD thiab noj rivaroxaban ib hnub ob zaug txhawm rau txo qhov kev pheej hmoo ntawm DVT thiab PE thiab ncua ib zaug, tsuas yog txuas ntxiv koj cov sijhawm noj tshuaj tas li. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Rivaroxaban yuav ua rau muaj kev mob tshwm sim. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

  • mob leeg pob

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no lossis cov uas teev rau hauv seem ceeb toom ceeb toom, hu rau koj tus kws kho mob tam sim ntawd:

  • los ntshav, dub, lossis quav tawv tsiaj
  • paj yeeb, lossis zis daj
  • hnoos lossis ntuav ntshav lossis tej khoom uas zoo li thaj chaw kas fes
  • nquag los ntswg
  • los ntshav los ntawm koj cov pos hniav
  • hnyav ntshav tawm los ntshav
  • tsis muaj zog
  • nkees nkees
  • mob taub hau
  • kiv tob hau lossis tsaus muag
  • qhov muag plooj
  • mob mob nyob sab caj npab lossis txhais ceg
  • ua pob
  • khaus
  • ua pa nyuaj lossis nqos
  • khaus
  • mob lossis o ntawm qhov chaw mob

Rivaroxaban txwv tsis pub cov ntshav txhaws khov kho yog li nws yuav siv sijhawm ntev dua li niaj hnub rau koj kom tsis txhob los ntshav yog tias koj raug txiav lossis raug mob. Cov tshuaj no tseem tuaj yeem ua rau koj doog ntshav lossis los ntshav yooj yim dua. Hu rau koj tus kws kho mob tam sim ntawd yog tias los ntshav lossis doog ntshav yog qhov txawv.

Rivaroxaban yuav ua rau muaj lwm cov kev mob tshwm sim. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm qhov kub thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Cov tsos mob ntawm kev noj haus ntau heev yuav suav nrog cov hauv qab no:

  • ntshav txawv lossis doog ntshav
  • los ntshav, dub, lossis quav tawv tsiaj
  • ntshav hauv zis
  • hnoos lossis ntuav ntshav lossis tej khoom uas zoo li thaj chaw kas fes

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee qhov kev kuaj sim kuaj xyuas koj lub cev cov lus teb rau rivaroxaban.

Tsis txhob cia lwm tus noj koj cov tshuaj. Koj cov ntawv yuav yog tej zaum yuav tsis ntxiv lawm.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

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