Rilpivirine

Zoo Siab

• Ua ntej noj rilpivirine,
• Rilpivirine yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, lossis cov uas teev rau hauv TSHWJ XEEB PRECAUTIONS, hu rau koj tus kws kho mob tam sim ntawd:
• Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no ib txwm tsis noj rilpivirine thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

Rilpivirine yog siv nrog rau lwm cov tshuaj los kho tib neeg hom tshuaj tiv thaiv kab mob (HIV-1) hauv qee tus neeg laus thiab menyuam yaus hnub nyoog 12 xyoos thiab laus dua uas hnyav tsawg kawg yog 77 lb (35 kg) thiab tsis tau txais kev kho mob antiretroviral yav dhau los. Nws kuj tseem siv nrog cabotegravir (Vocabria) ua kev tiv thaiv luv luv-mob HIV-1 rau qee tus neeg laus. Rilpivirine nyob hauv chav kawm ntawm cov tshuaj hu ua non-nucleoside rov qab transcriptase inhibitors (NNRTIs). Nws ua haujlwm los ntawm kev txo qis hauv cov HIV hauv cov ntshav. Txawm hais tias rilpivirine tsis kho HIV, nws yuav txo koj txoj hmoo los ntawm kev tiv thaiv kab mob (AIDS) thiab mob ntsig txog HIV xws li kis mob hnyav lossis mob qog ntshav. Noj cov tshuaj no nrog rau kev xyaum sib deev kom nyab xeeb thiab hloov pauv lwm yam hauv lub neej yuav txo qhov kev pheej hmoo kis tus mob HIV mus rau lwm tus neeg.

Rilpivirine los ua ib ntsiav tshuaj noj ntawm qhov ncauj. Nws feem ntau yog noj nrog zaub mov (tsis yog haus dej haus kua protein) ib hnub ib zaug. Thaum rilpivirine noj nrog cabotegravir, feem ntau nws noj ib hnub ib zaug nrog pluas noj. Noj rilpivirine ib leeg lossis nrog cabotegravir nyob ib ncig ntawm tib lub sijhawm txhua hnub. Rilpivirine noj nrog cabotegravir rau kwv yees li ib hlis (ntev tsawg kawg 28 hnub) ua ntej pib kho nrog cov tshuaj siv ntev ntev ntawm cov tshuaj no lossis ntev txog 2 lub hlis yog tias lub sijhawm txhaj tshuaj tsis haum rau ntau tshaj 7 hnub. Ua raws li cov lus qhia ntawm koj daim ntawv sau tshuaj noj kom zoo, thiab nug koj tus kws kho mob lossis kws muag tshuaj kom piav qhia ib feem uas koj tsis nkag siab. Noj rilpivirine raws nraim li qhia. Tsis txhob noj ntau dua lossis tsawg dua lossis siv ntau dua li uas koj tus kws khomob tau qhia.

Rilpivirine tswj hwm HIV tab sis nws tsis kho nws. Txuas ntxiv noj rilpivirine txawm hais tias koj tus kheej yuav xis neej. Tsis txhob tsum noj rilpivirine yam tsis tau tham nrog koj tus kws kho mob. Thaum koj cov mov ntawm rilpivirine pib khiav qis, tau ntau los ntawm koj tus kws kho mob lossis kws muag tshuaj. Yog tias koj plam koob tshuaj lossis tso tseg tsis noj rilpivirine, koj tus mob yuav nyuaj kho tus mob.

Nug koj tus kws muag tshuaj lossis tus kws kho mob txog cov ntawv luam ntawm cov ntaub ntawv tsim tawm rau tus neeg mob.

Cov tshuaj no tuaj yeem tsim tawm rau lwm txoj kev siv; nug koj tus kws kho mob lossis kws muag tshuaj kom paub ntaub ntawv ntau ntxiv.

Ua ntej noj rilpivirine,

• qhia rau koj tus kws kho mob thiab tus kws muag tshuaj yog tias koj muaj kev fab tshuaj rau rilpivirine, lwm yam tshuaj, lossis ib qho twg hauv cov tshuaj rilpivirine. Nug koj tus kws muag tshuaj rau cov npe ntawm cov khoom xyaw.
• qhia rau koj tus kws kho mob yog tias koj noj cov dexamethasone (Decadron); cov tshuaj noj rau qaug dab peg xws li carbamazepine (Carbatrol, Epitol, Euetro, Tegretol, Teril), oxcarbazepine (Trileptal), phenobarbital (Luminal), lossis phenytoin (Dilantin, Phenytek); proton twj tso kua mis inhibitors suav nrog dexlansoprazole (Dexilant), esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), lossis rabeprazole (Aciphex); phom phom (Rifater, Rifamate, Rimactane, Rifadin); rab phom loj (Priftin); thiab St. John lub wort. Koj tus kws kho mob yuav qhia koj kom tsis txhob noj rilpivirine yog tias koj noj ib lossis ntau dua ntawm cov tshuaj no.
• qhia rau koj tus kws kho mob thiab kws muag tshuaj tias lwm yam tshuaj uas tsis yog kws kho mob thiab cov tshuaj uas tsis yog kws kho mob sau, tshuaj vitamins, khoom noj khoom haus zoo, thiab tshuaj ntsuab koj tau noj lossis npaj yuav noj. Nco ntsoov hais txog ib qho ntawm cov hauv qab no: cov tshuaj tua kab mob, suav nrog fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), thiab voriconazole (Vfend); amiodarone (Nexterone, Pacerone); anagrelide (Agrylin); chloroquine; chlorpromazine; cilostazol; ciprofloxacin (Cipro); citalopram (Celexa); clarithromycin (Biaxin); disopyramide (Norpace); dofetilide (Tikosyn); ua cov tshuaj tiav (Aricept); erythromycin (E-Mycin, Eryc, Ery-Tab, PCE, Pediazole); flecainide (Tambocor); haloperidol (Haldol); ibutilide (Hloov); levofloxacin; tshuaj txiav yeeb (Dolophine); moxifloxacin (Velox); nelfinavir (Viracept); ondansetron (Zuplenz, Zofran); lwm cov NNRTIs tshuaj kho mob HIV / AIDS; pentamidine (NebuPent, Pentam); pimozide (Orap); procainamide; quinidine (hauv Nuedexta); rifabutin (Mycobutin); sotalol (Betapace, Tshais, Sotylize); telithromycin (Ketek); thiab thioridazine. Koj tus kws kho mob tej zaum yuav tau hloov qhov tshuaj ntawm koj cov tshuaj lossis saib xyuas koj kom zoo rau kev phiv. Ntau lwm yam tshuaj muaj peev xwm kuj tseem cuam tshuam nrog rilpivirine, yog li nco ntsoov qhia koj tus kws kho mob txog txhua yam tshuaj uas koj siv, txawm tias tsis tshwm nyob hauv daim ntawv no.
• yog tias koj noj tshuaj antacids uas muaj calcium, magnesium, lossis txhuas (Maalox, Mylanta, Tums, lwm tus), coj lawv tsawg kawg 2 teev ua ntej lossis 4 teev tom qab rilpivirine.
• yog tias koj noj tshuaj rau kem plab, kub siab, lossis mob rau sab hauv xws li cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), lossis ranitidine (Zantac), noj nws tsawg kawg 12 teev ua ntej lossis tsawg kawg 4 teev tom qab rilpivirine Cov.
• yog tias koj noj didanosine (Videx), noj tsawg kawg 2 teev ua ntej lossis tsawg kawg 4 teev tom qab rilpivirine.
• qhia rau koj tus kws kho mob yog tias koj tau lossis muaj dua li muaj kev nyuaj siab lossis lwm yam kev mob hlwb, kab mob siab, nrog rau daim siab mob siab B lossis C, lossis mob raum.
• qhia rau koj tus kws kho mob yog tias koj cev xeeb tub los yog npaj yuav cev xeeb tub. Yog tias koj cev xeeb tub thaum noj rilpivirine, hu rau koj tus kws kho mob. Qhia rau koj tus kws kho mob yog tias koj pub mis niam rau menyuam. Koj yuav tsum tsis txhob noj niam mis yog tias koj kis nrog HIV lossis yog tias koj noj tshuaj rilpivirine.
• koj yuav tsum paub tias koj lub cev rog tuaj yeem nce lossis txav mus rau thaj chaw ntawm koj lub cev xws li koj lub mis, lub nraub qaum thiab caj dab, lossis ib puag ncig ntawm koj lub cev. Kev poob rog los ntawm txhais ceg, caj npab, thiab ntsej muag kuj tuaj yeem tshwm sim.
• koj yuav tsum paub tias rilpivirine tuaj yeem hloov pauv koj txoj kev xav, kev coj cwj pwm, lossis lub hlwb. Hu rau koj tus kws kho mob tam sim ntawd yog tias koj muaj ib qho ntawm cov tsos mob hauv qab no thaum koj noj rilpivirine: kev nyuaj siab tshiab lossis zuj zus; xav tu siab, tag kev cia siab, ntxhov siab, los sis nyob tsis tswm; lossis xav txog kev tua koj tus kheej lossis npaj lossis sim ua li ntawd. Nco ntsoov tias koj tsev neeg paub tias tus mob yuav mob dab tsi es lawv thiaj li hu tau koj tus kws kho mob yog tias koj tsis tuaj yeem nrhiav kev kho koj tus kheej.
• koj yuav tsum paub tias thaum koj tab tom noj tshuaj los kho kab mob HIV, koj lub cev tiv thaiv kab mob yuav muaj zog thiab pib tawm tsam lwm yam kev mob uas twb muaj hauv koj lub cev lossis ua rau lwm yam mob tshwm sim. Qhov no tuaj yeem ua rau koj tsim cov tsos mob ntawm cov mob lossis cov mob. Yog tias koj muaj cov tsos mob tshiab lossis mob hnyav tom qab pib kho nrog rilpivirine, nco ntsoov qhia koj tus kws kho mob.

Tshwj tsis yog koj tus kws kho mob hais rau koj lwm yam, txuas ntxiv koj li kev noj haus zoo.

Noj cov koob tshuaj uas ploj lawm sai li sai tau thaum koj nco txog nws, nrog noj mov. Txawm li cas los xij, yog tias nws tau ntau dua 12 teev txij li koj cov tshuaj kawg, hla cov koob tshuaj uas tsis nco qab thiab ua ntxiv rau koj cov caij nyoog noj tshuaj tas li. Tsis txhob noj tshuaj rau ob zaug kom ua rau qhov ploj lawm ib zaug.

Rilpivirine yuav ua rau muaj kev phiv tshuaj. Qhia rau koj tus kws kho mob yog tias ib qho ntawm cov tsos mob no hnyav lossis tsis ploj mus:

• teeb meem tsis tsaug zog los yog pw tsaug zog
• mob taub hau
• xeev siab
• ntuav
• kiv taub hau
• mob plab
• tsaug zog

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog tias koj muaj cov tsos mob no, lossis cov uas teev rau hauv TSHWJ XEEB PRECAUTIONS, hu rau koj tus kws kho mob tam sim ntawd:

• ua pob
• daj tawv nqaij lossis qhov muag, hnov ​​mob sab xis ntawm lub plab, xeev siab, ntuav, tso quav ua ke, tso zis dub

Qee qhov kev mob tshwm sim tuaj yeem loj heev. Yog koj muaj cov tsos mob no ib txwm tsis noj rilpivirine thiab hu rau koj tus kws kho mob tam sim ntawd lossis tau txais kev kho mob kub ceev:

• ua pob nrog kub taub hau, o ntawm lub ntsej muag, daim di ncauj, qhov ncauj, nplaig lossis lub caj pas, hlwv, muaj teeb meem ua pa lossis nqos, qhov ncauj tawm ntawm qhov muag, liab lossis o ntawm lub qhov muag (mob), mob nyob rau sab xis ntawm lub plab (tsam plab) thaj chaw, lossis cov zis dub zoo nkauj

Rilpivirine yuav ua rau muaj kev phiv ntxiv. Hu rau koj tus kws kho mob yog tias koj muaj teeb meem txawv txawv thaum noj cov tshuaj no.

Yog tias koj muaj kev mob tshwm sim loj, koj lossis koj tus kws kho mob tuaj yeem xa ntawv ceeb toom rau Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) lossis hauv xov tooj ( 1-800-332-1088).

Khaws cov tshuaj no rau hauv lub khob uas nws nkag los, kaw kom nruj, thiab ncav tsis cuag ntawm cov menyuam. Khaws nws ntawm chav sov thiab deb ntawm lub teeb, tshaj cua sov thiab noo noo (tsis nyob hauv chav dej).

Nws yog ib qho tseem ceeb kom tsis txhob muaj txhua yam tshuaj rau qhov tsis pom thiab ncav cuag ntawm cov menyuam yaus ntau li ntau ntim (xws li tshuaj ntsiav tshuaj txhua lub limtiam thiab cov tshuaj rau qhov muag, tshuaj pleev, pleev xim, thiab nqus tshuaj) tsis tiv thaiv menyuam yaus thiab cov menyuam yaus tuaj yeem qhib lawv tau yooj yim. Txhawm rau tiv thaiv cov menyuam yaus me los ntawm kev lom, ib txwm kaw lub kaus mom kev nyab xeeb thiab muab cov tshuaj tso rau qhov chaw nyab xeeb - ib qho chaw nyob thiab deb thiab tawm ntawm lawv pom thiab ncav cuag. http://www.upandaway.org

Cov tshuaj tsis siv tshuaj yuav tsum tau muab pov tseg hauv txoj kev tshwj xeeb kom ntseeg tau tias cov tsiaj, menyuam yaus, thiab lwm tus neeg tsis tuaj yeem haus lawv. Txawm li cas los xij, koj yuav tsum tsis txhob yaug cov tshuaj no hauv lub qhov viv. Hloov chaw, txoj hauv kev zoo tshaj plaws hauv kev muab koj cov tshuaj tshem tawm yog los ntawm kev siv tshuaj rov qab. Tham nrog koj tus kws muag tshuaj lossis tiv tauj koj lub chaw khaws khib nyiab / chaw khaws khoom ubno hauv ib cheeb tsam kom paub txog cov haujlwm thim rov qab hauv koj lub zej zog. Saib ntawm FDA's Kev Nyab Xeeb Kev Nyab Xeeb Kev Siv Tshuaj lub vev xaib (http://goo.gl/c4Rm4p) kom paub cov ntaub ntawv ntau ntxiv yog tias koj tsis muaj kev nkag mus saib rov qab.

Yog hais tias noj ntau dhau, hu rau kem tus xov tooj kev pab tswj kev lom ntawm 1-800-222-1222. Cov ntaub ntawv tseem muaj nyob online ntawm https://www.poisonhelp.org/help. Yog tus neeg raug tsim txom, tsaus muag, ua tsis taus pa, lossis sawv tsis taus, hu rau 911 tus neeg pab thaum muaj xwm ceev.

Khaws tag nrho cov kev teem caij mus ntsib koj tus kws kho mob thiab chav kuaj mob. Koj tus kws kho mob yuav xaj qee yam kev kuaj sim kuaj seb koj lub cev teb li cas rau rilpivirine.

Tsis txhob cia lwm tus noj koj cov tshuaj. Nug koj tus kws muag tshuaj cov lus nug uas koj muaj txog kev rov ntxiv tshuaj rau koj.

Muab khaws cia ntawm rilpivirine ntawm tes. Tsis txhob tos kom txog thaum koj khiav tawm ntawm cov tshuaj rau koj cov tshuaj noj.

Nws yog ib qho tseem ceeb rau koj kom koj muaj ib daim ntawv sau tag nrho cov tshuaj noj thiab cov tshuaj uas tsis yog kws kho mob sau ntawv (tsis yuav khoom) uas koj tab tom noj, nrog rau txhua yam khoom xws li cov vitamins, minerals, lossis lwm yam tshuaj noj rau lub cev. Koj yuav tsum nqa cov ntawv no nrog koj txhua zaus koj mus ntsib kws kho mob lossis yog tias koj tuaj nyob hauv tsev kho mob. Nws tseem yog cov ntaub ntawv tseem ceeb los nqa nrog koj thaum muaj xwm txheej ceev.

• Edurant^®
• Juluca^® (raws li cov khoom sib txuas ua ke uas muaj dolutegravir, rilpivirine)