Parathyroid mob cancer
Parathyroid cancer yog mob qog noj ntshav (qog nqaij hlav hlav) hauv cov roj ntsha parathyroid.
Parathyroid qog tswj cov calcium qib hauv lub cev. Muaj 4 parathyroid caj pas, 2 nyob rau sab saum toj ntawm txhua lobe ntawm cov thyroid caj pas, uas nyob ntawm lub hauv paus ntawm caj dab.
Parathyroid cancer yog hom mob qog nqaij hlav uas tsawg tsawg. Nws cuam tshuam rau txiv neej thiab poj niam sib npaug. Tus mob khees xaws feem ntau tshwm sim rau cov neeg laus dua 30 xyoo.
Vim li cas ho tsis paub txog mob hlwb parathyroid. Cov neeg muaj caj ces hu ua ntau yam keeb endocrine neoplasia hom I thiab hyperparathyroidism-puab tsaig nqaij hlav muaj ntau txoj kev pheej hmoo rau tus mob no. Cov neeg uas tau txais hluav taws xob taub hau lossis caj dab kuj yuav muaj feem ntau dua. Tab sis hom hluav taws xob no ntau dua yuav ua rau muaj mob qog nqaij hlav cancer.
Cov tsos mob ntawm tus mob qog noj ntshav parathyroid feem ntau yog los ntawm kev muaj calcium ntau nyob hauv cov ntshav (hypercalcemia), thiab yuav cuam tshuam rau ntau qhov chaw ntawm lub cev.
Cov tsos mob muaj xws li:
- Mob pob txha
- Cem quav
- Nkees
- Puas taus
- Nquag nqhis dej heev
- Nquag tso zis ntau zaus
- Raum pob zeb
- Nqaij tsis muaj zog
- Xeev siab thiab ntuav
- Tsis qab los noj mov
Parathyroid mob cancer yog qhov nyuaj rau kev txheeb xyuas.
Koj tus kws kho mob yuav kuaj lub cev thiab nug txog koj li keeb kwm kho mob.
Kwv yees li ib nrab ntawm lub sijhawm, tus kws kho mob pom tus mob parathyroid los ntawm kev mob siab caj dab nrog txhais tes (palpation).
Kev mob qog noj ntshav parathyroid feem ntau ua rau cov hlwb parathyroid ntau heev (PTH). Kev kuaj mob rau cov tshuaj hormones no suav nrog:
- Ntshav calcium
- Ntshav PTH
Ua ntej kev phais mob, koj yuav muaj qhov tshwj xeeb xoo hluav taws xob tsom ntawm cov qog ntshav parathyroid. Lub scan yog hu ua sestamibi scan. Koj kuj tseem yuav muaj caj dab ultrasound. Cov kev kuaj no tau ua tiav kom paub tseeb tias qhov twg parathyroid caj pas yog qhov txawv txav.
Cov kev kho mob hauv qab no yuav raug siv los kho hypercalcemia vim yog mob hlwb parathyroid:
- Cov kua dej los ntawm cov ntshav (IV dej)
- Lub ntuj lawm hu ua calcitonin uas pab tswj cov qib calcium
- Cov tshuaj uas nres kev tawg thiab rov thim pob txha hauv lub cev
Kev phais mob yog qhov pom zoo kev kho mob parathyroid mob cancer. Qee zaum, nws tsis yooj yim los tshawb pom yog tias tus kabmob hlwb parathyroid yog cov kabmob. Koj tus kws kho mob yuav pom zoo kom phais txawm tias tsis muaj kev kuaj mob paub tseeb. Txoj kev phais tsawg tsawg, siv kev txiav me me, ua rau muaj tus mob parathyroid.
Yog tias kev ntsuam xyuas ua ntej kev phais yuav pom lub caj pas muaj kev cuam tshuam, kev phais mob yuav ua rau ntawm ib sab ntawm lub caj dab. Yog tias nws nrhiav tsis tau teeb meem qog ua ntej kev phais mob, tus kws phais yuav saib ob sab ntawm koj lub caj dab.
Kws khomob thiab hluav taws xob tua tsis zoo yuav pab tiv thaiv kom txhob mob cancer rov qab los. Kev xoo hluav taws xob tuaj yeem pab txo qis kev mob qog nqaij hlav mus rau cov pob txha.
Rov ua dua phais mob rau cov qog noj ntshav uas rov qab tuaj yeem pab tau:
- Txhim kho tus nqi ntawm kev ua neej nyob
- Txo cov kev cuam tshuam loj heev los ntawm hypercalcemia
Parathyroid cancer yog qeeb hlob. Kev phais mob tuaj yeem pab txuas lub neej ntev txawm tias mob cancer kis.
Tus mob yuav kis tau (metastasize) rau lwm qhov hauv lub cev, feem ntau mob ntsws thiab pob txha.
Hypercalcemia yog qhov hnyav tshaj plaws. Feem ntau cov neeg tuag los ntawm parathyroid mob cancer tshwm sim vim yog mob nyhav, nyuaj-los tswj ntshav hypercalcemia, thiab tsis yog mob cancer nws tus kheej.
Tus kabmob kheev feem ntau rov qab los (rov ua dua). Tej zaum yuav raug phais ntxiv. Cov teeb meem los ntawm kev phais mob tuaj yeem suav nrog:
- Lub suab tsis zoo lossis lub suab hloov raws li kev puas tsuaj rau cov hlab ntsha uas tswj lub suab nrov
- Kev kis rau ntawm qhov chaw ntawm kev phais mob
- Qib calcium ntau nyob hauv cov ntshav (hypocalcemia), uas muaj feem ua rau tuag taus
- Caws pliav
Hu rau koj tus kws kho mob yog tias koj hnov mob qa ntawm koj lub caj dab lossis hnov mob hypercalcemia.
Parathyroid carcinoma
- Parathyroid qog
Asban A, Patel AJ, Reddy S, Wang T, Balentine CJ, Chen H. Cancer ntawm endocrine system. Hauv: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical OncologyCov. 6 tus ed. Philadelphia, PA: Elsevier; 2020: chap 68.
Fletcher CDM. Cov qog ntawm cov qog thiab parathyroid qog. Hauv: Fletcher CDM, ed. Kev kuaj mob keeb kwm ntawm lub pobCov. Thib 5 ed. Philadelphia, PA: Elsevier; 2021: chap 18.
Lub koom haum Cancer National website. Kev kho mob cancer Parathyroid (PDQ) - kev noj qab haus huv cov qauv. www.cancer.gov/types/parathyroid/hp/parathyroid-nyuj-pdq. Hloov kho thaum Lub Peb Hlis 17, 2017. Nkag mus rau Lub Ob Hlis 11, 2020.
Torresan F thiab J Iacobone M. Cov haujlwm sib txawv, kev kho mob thiab kev saib xyuas ntawm hyperparathyroidism-lub puab tsaig mob syndrome: Ib qho hloov tshiab thiab rov saib cov ntawv nyeem. Int J Endocrinol 2019Cov. Pub luam tawm online Dec 18, 2019. www.hindawi.com/journals/ije/2019/1761030/.