Kev kuaj ntshav TBG

Kev kuaj ntshav TBG ntsuas qib ntawm cov protein uas txav cov thyroid hormone thoob plaws hauv koj lub cev. Cov protein no hu ua thyroxine binding globulin (TBG).

Kev kuaj ntshav tawm thiab mam li xa mus rau qhov chaw kuaj ntshav kuaj.

Qee yam tshuaj thiab cov tshuaj muaj peev xwm cuam tshuam rau kev sim tshuaj. Koj tus kws kho mob yuav hais kom koj tsum tsis txhob noj qee yam tshuaj ua ntej luv luv. Tsis txhob tsum tsis noj cov tshuaj yam tsis tau tham ua ntej nrog koj tus kws kho mob.

Cov tshuaj thiab cov tshuaj no tuaj yeem nce TBG ntxiv:

• Estrogens, pom hauv cov tshuaj txwv thiab tshuaj kho estrogen
• Neeg Hus Npe
• Tshuaj txiav yeeb
• Phenothiazines (qee yam tshuaj tiv thaiv kev puas tsuaj)

Cov tshuaj hauv qab no tuaj yeem txo qis dua TBG:

• Depakote lossis depakene (tseem hu ua valproic acid)
• Dilantin (tseem hu ua phenytoin)
• Kev noj tshuaj salicylates siab ntau, suav nrog cov tshuaj aspirin
• Txiv neej cov tshuaj hormones, suav nrog androgens thiab testosterone
• Prednisone

Thaum cov koob tau tso rau hauv cov ntshav, qee cov neeg hnov ​​mob me ntsis. Lwm tus ho hnov ​​tus mob lossis ceg tawv xwb. Tom qab ntawd, tej zaum yuav muaj qee qhov duav lossis pob me me. Tsis ntev no ploj mus.

Qhov kev sim no yuav raug ua mus kuaj mob teeb meem nrog koj lub qog.

Qhov ntau thiab tsawg yog li 13 txog 39 micrograms per deciliter (mcg / dL), lossis 150 rau 360 nanomoles ib liter (nmol / L).

Cov kab ke tus nqi yuav txawv me ntsis ntawm ntau lub chaw soj nstuam. Qee qhov kuaj pom siv cov kev ntsuas sib txawv lossis sim cov qauv sib txawv. Tham nrog koj tus kws kho mob txog cov ntsiab lus ntawm koj cov kev kuaj sim.

Nce qib TBG ntau zog tuaj yeem yog vim:

• Mob sib quas ntus porphyria (muaj mob tsis txaus metabolic tsis txaus)
• Hypothyroidism (tsis zoo li lub qog)
• Mob siab
• Cev xeeb tub (TBG feem ntau nce ntxiv thaum cev xeeb tub)

Nco tseg: qib TBG feem ntau yog ib txwm muaj rau cov menyuam mos yug tshiab.

Cov qib TBG tsawg dua yuav yog vim:

• Mob mob
• Acromegaly (kev cuam tshuam los ntawm ntau dhau los kev loj hlob hormone)
• Hyperthyroidism (ua rau mob qog)
• Khoom noj khoom haus tsis muaj zog
• Tus mob Nifaisrotic (cov tsos mob qhia tias lub raum puas tam sim no)
• Kev ntxhov siab los ntawm kev phais mob

Cov qib TBG siab siab lossis qis qis cuam tshuam rau kev sib raug zoo ntawm tag nrho T4 thiab kuaj ntshav dawb T4. Hloov ntshav TBG ntau tuaj yeem hloov cov koob tshuaj levothyroxine hloov uas tsim nyog rau cov neeg mob hypothyroidism.

Txoj kev pheej hmoo me ntsis nrog kev coj koj cov ntshav mus. Cov leeg thiab cov hlab ntsha sib txawv raws li ib tug neeg mus rau lwm qhov thiab ntawm ib sab ntawm lub cev mus rau lwm qhov. Mus nqa cov ntshav los ntawm ib cov neeg tej zaum yuav nyuaj tshaj li los ntawm lwm tus.

Lwm yam kev pheej hmoo ntawm kev tso ntshav tawm me ntsis, tab sis yuav suav nrog:

• Los ntshav ntau
• Tsaus muag lossis hnov ​​nkaus lub teeb
• Ntau cov punctures los nrhiav cov leeg ntshav
• Hematoma (ntshav buildup hauv qab daim tawv nqaij)
• Kev kis tus kab mob (muaj kev pheej hmoo me me txhua lub sijhawm ntawm daim tawv tawg)

Ntshav dej thyroxine losis tswvyim dabtsi globulin; Qib TBG; Ntsig txog qib TBG; Hypothyroidism - TBG; Hyperthyroidism - TBG; Tsis txaus ntseeg cov thyroid - TBG; Tsaus cov thyroid - TBG

• Kuaj ntshav

Guber HA, Farag AF. Kev soj ntsuam ntawm endocrine muaj nuj nqi. Hauv: McPherson RA, Pincus MR, eds. Henry's Kev Kuaj Mob thiab Kev Tswj Xyuas los ntawm Laboratory Txoj KevCov. 23rd ed. St Louis, MO: Elsevier; 2017: chap 24.

Kruse JA. Lub qog ua kom mob siab. Hauv: Parrillo JE, Dellinger RP, eds. Cov Tshuaj Kho Mob Nkeeg: Cov hauv paus ntsiab lus ntawm kev kuaj mob thiab Kev Tswj Xyuas hauv Cov Neeg Loj. Thib 5 ed. Philadelphia, PA: Elsevier; 2019: chap 57.

Salvatore D, Cohen R, Kopp PA, Larsen PR. Cov thyroid pathophysiology thiab tshuaj ntsuam xyuas mob. Hauv: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Phau Ntawv ntawm EndocrinologyCov. Xab 14th. Philadelphia, PA: Elsevier; 2020: chap 11.