Hloov hlwb pob txha

Kev hloov hlwb pob txha yog txheej txheem los hloov cov hlwb pob txha puas los yog rhuav tshem nrog hlwb pob txha hlwb zoo.

Cov pob txha txha yog cov nqaij mos, rog hauv koj cov pob txha. Cov hlwb pob txha tsim cov qe ntshav. Qia hlwb yog cov qe ntshav tsis txaus nyob hauv cov hlwb pob txha uas ua rau muaj tag nrho koj cov ntshav txawv.

Ua ntej hloov ntshav, siv tshuaj tua hluav taws xob, kho hluav taws xob, lossis ob yam puav leej muab tau. Qhov no tuaj yeem ua ob qho:

• Kev kho mob tsis nco qab (myeloablative) - Kev siv tshuaj ntau dua, hluav taws xob, lossis ob qho tib si raug muab los tua txhua cov qog nqaij hlav cancer. Qhov no kuj tua tau tag nrho cov hlwb pob txha zoo uas tseem tshuav, thiab tso cai rau cov qia hlwb tshiab loj tuaj ntawm cov hlwb pob txha.
• Txo cov kev siv dag zog ntau, kuj hu ua kev hloov me me - Kev qis qis ntawm kev siv tshuaj thiab hluav taws xob tau muab ua ntej hloov ntshav. Qhov no pub rau cov neeg laus dua, thiab cov neeg muaj lwm yam mob tuaj yeem hloov pauv hloov tau.

Muaj peb yam kev hloov hlwb pob txha:

• Txoj kev hloov cov hlwb pob txha Autologous - Lo lus pib txhais tau tias yog tus kheej. Cov qia hlwb raug tshem tawm ntawm koj ua ntej koj tau txais kev siv tshuaj kho mob lossis kho hluav taws xob ntau. Cov kab mob hlwb yog khaws cia hauv lub tub yees. Tom qab kev siv tshuaj lossis tshuaj tua hluav taws xob ntau, koj lub qia hlwb muab rov qab rau hauv koj lub cev los ua cov qe ntshav li qub. Qhov no yog hu ua kev hloov pauv.
• Hloov pob txha hauv Allogeneic - Lub sij hawm allo txhais tau tias yog lwm yam. Cov qia hlwb raug tshem tawm los ntawm lwm tus neeg, hu ua tus neeg pub nyiaj. Feem ntau, cov pub khoom nruab nrog yuav tsum muaj tsawg kawg ib feem phim koj cov noob. Kev ntsuam xyuas tshwj xeeb yog ntsuas kom pom tias tus neeg pub nyiaj yog qhov txiaj ntsig zoo rau koj. Kwv tij los yog nkauj muam feem ntau yuav tau sib phim zoo. Qee zaum cov niam txiv, menyuam thiab lwm tus neeg txheeb ze yog cov khoom zoo. Cov neeg pub nyiaj uas tsis cuam tshuam nrog koj, tseem tseem phim koj, tej zaum yuav nrhiav pom los ntawm cov neeg muaj pob txha caj dab.
• Hloov hlab ntaws ntshav hlab ntaws - Qhov no yog ib hom kev hloov pauv allogeneic. Cov qia qia tawm ntawm tus me nyuam mos txoj hlab ntaws tam tom qab tau yug los. Lub hlwb qia khov thiab muab khaws cia kom txog thaum lawv xav tau rau qhov hloov ntshav. Umbilical qaum ntshav cov qe ntshav tsis txaus siv me me thiaj li muaj tsawg dua qhov xav tau kev sib txuam zoo meej. Vim tias cov qog hlwb me dua, cov ntshav suav tau siv sijhawm ntev dua los ua kom rov zoo dua.

Kev hloov qia ua qog feem ntau yog ua tiav tom qab kho cov tshuaj thiab hluav taws xob tiav. Cov qia hlwb xa mus rau hauv koj cov hlab ntshav, feem ntau yog los ntawm lub raj hu ua central venous catheter. Cov txheej txheem zoo ib yam li tau txais ntshav ntxiv. Cov qia ntshav mus los ntawm cov ntshav mus rau cov leeg pob txha. Feem ntau, tsis tas yuav muaj kev phais.

Pub cov qia hlwb yuav khaws tau ob txoj hauv kev:

• Kev ua qoob loo rau pob txha - Qhov kev phais me me no tau ua nyob hauv kev siv tshuaj loog. Qhov no txhais tau tias tus pub dawb yuav tsaug zog thiab tsis hnov ​​tshuaj thaum ua cov txheej txheem. Cov leeg mob pob txha raug tshem tawm los ntawm sab nraub qaum ntawm ob sab pob txha hip. Tus nqi ntawm cov marrow muab tshem tawm yog nyob ntawm qhov hnyav ntawm tus neeg uas tau txais nws.
• Leukapheresis - Ua ntej, cov neeg pub ntshav tau muab ob peb hnub txhaj tshuaj los pab cov qia hlwb txav los ntawm cov hlwb pob txha mus rau hauv cov ntshav. Thaum mob leukapheresis, ntshav raug tshem tawm ntawm tus neeg pub ntshav los ntawm txoj xov IV. Qhov txheej txheem ntawm cov qe ntshav dawb uas muaj cov qia hlwb raug cais tawm hauv lub tshuab thiab tshem tawm tom qab muab rau tus neeg txais. Cov ntshav liab ua rov qab muab rau tus pub.

Hloov hlwb pob txha los hloov hlwb pob txha uas tsis ua haujlwm zoo los yog raug rhuav tshem (txo qis) los ntawm kev siv tshuaj kho mob lossis hluav taws xob. Cov kws kho mob ntseeg tias rau ntau yam mob qog noj ntshav, cov neeg pub ntshav dawb tuaj yeem tua cov qe ntshav ntxiv, zoo ib yam li cov qe dawb tua cov kab mob lossis cov vais vais thaum sib ntaus sib kis mob.

Koj tus kws kho mob yuav qhia kom hloov hlwb pob txha yog tias koj muaj:

• Qee yam mob qog nqaij hlav, xws li mob rwj ntshav, mob qog nqaij hlav, mob myelodysplasia, lossis ntau yam mob myeloma.
• Ib tug kabmob uas cuam tshuam rau kev tsim cov pob txha hlwb, xws li mob ntshav tsis txaus, ntshav qog txha ntshav hlab plawv, mob tsis muaj zog tiv thaiv kab mob, mob ntshav rau lub cev ntshav, lossis ntshav thalassemia.

Hloov hlwb pob txha yuav ua rau cov tsos mob nram qab no:

• Kev mob hauv siab
• Ua ntshav siab
• Ua npaws, ua daus no, tawm los
• Lom zem funny hauv lub qhov ncauj
• Mob taub hau
• Khaus Khawb
• Xeev siab
• Mob
• Ua tsis taus pa

Muaj teeb meem rau kev hloov hlwb pob txha nyob ntawm ntau yam, suav nrog:

• Koj lub hnub nyoog
• Koj txoj kev noj qab haus huv tag nrho
• Zoo npaum li cas ntawm qhov phim koj tus pub
• Hom kev hloov hlwb pob txha uas koj tau txais (autologous, allogeneic, lossis hlab ntshav hlab ntaws)

Teeb meem yuav suav nrog:

• Mob Kev Plab
• Los ntshav hauv lub ntsws, txoj hnyuv, lub paj hlwb, thiab lwm qhov chaw ntawm lub cev
• Cataracts
• Clotting hauv cov leeg me me ntawm daim siab
• Kev puas tsuaj rau lub raum, mob siab, mob ntsws, thiab mob plawv
• Ncua kev loj hlob ntawm cov menyuam yaus uas tau hloov hlwb pob txha
• Ntxov ntxov lawm
• Kev sib tsoo tsis ua hauj lwm, uas txhais tau hais tias cov hlwb tshiab tsis mus rau hauv lub cev thiab pib tsim cov qia ua kua
• Graft-tiv tiag-party kab mob (GVHD), tus mob uas cov hlwb pub dawb tua koj lub cev
• Cov kab mob kis tau, uas tuaj yeem ua mob hnyav heev
• O thiab mob hauv lub qhov ncauj, caj pas, txoj hlab nqos mov, thiab lub plab, hu ua mucositis
• Mob
• Cov teeb meem hauv plab, suav nrog raws plab, xeev siab thiab ntuav

Koj tus kws khomob yuav nug txog koj li keeb kwm kev khomob thiab kuaj mob lub cev. Koj yuav muaj ntau yam kev sim ua ntej pib kho.

Ua ntej hloov ntshav, koj yuav muaj 1 lossis 2 leeg, hu ua central venous catheters, ntxig rau hauv cov hlab ntshav hauv koj lub caj dab lossis caj npab. Cov raj no tso cai rau koj kom tau txais kev kho mob, haus dej, thiab qee zaum kev noj haus. Nws kuj yog siv los kos ntshav.

Koj tus kws kho mob yuav tham txog qhov kev ntxhov siab zoo siab los ntawm kev hloov hlwb pob txha. Tej zaum koj yuav xav ntsib nrog ib tus kws sab laj. Nws yog ib qho tseem ceeb los tham nrog koj tsev neeg thiab menyuam kom pab lawv to taub dab tsi tshwm sim.

Koj yuav tsum tau npaj kev ua haujlwm los pab koj npaj cov txheej txheem thiab ua cov haujlwm tom qab koj hloov ntshav:

• Ua kom tiav daim ntawv qhia ua ntej txog kev saib xyuas
• Teem sijhawm rau kev kho mob tawm haujlwm
• Saib xyuas cov txhab nyiaj lossis cov lus qhia nyiaj txiag
• Npaj kev tu ntawm cov tsiaj
• Npaj ib tug neeg los pab nrog haujlwm hauv tsev
• Paub meej tias ntawv pov hwm kev pov hwm them nqi kho mob
• Them nuj nqis
• Npaj saib xyuas koj cov menyuam
• Nrhiav tsev nyob rau koj tus kheej lossis koj tsev neeg nyob ze tsev khomob, yog xav tau

Kev hloov cov pob txha hloov pob txha feem ntau yog ua hauv tsev kho mob lossis chaw kho mob uas tshwj xeeb hauv kev kho mob. Feem ntau, koj nyob hauv chav hloov pob txha tshwj xeeb hauv nruab nrab. Nov yog koj tsuas muaj feem ua kom kis tus mob.

Nyob ntawm kev kho mob thiab qhov twg nws ua tiav, txhua yam lossis ib feem ntawm kev hloov khoom siv ntshav lossis lub cev hloov pauv tuaj yeem kho tau sab nraud. Qhov no txhais tau tias koj tsis tas yuav pw hauv tsev kho mob thaum hmo ntuj.

Lub sijhawm koj nyob hauv tsev khomob ntev npaum li cas yog nyob ntawm:

• Txawm hais tias koj tau tsim ib qho teeb meem ntsig txog qhov hloov ntshav
• Hom kev hloov pauv
• Koj lub tsev kho mob cov txheej txheem

Thaum koj tseem nyob hauv tsev kho mob:

• Cov neeg saib xyuas kev noj qab haus huv yuav saib xyuas koj cov ntshav thiab cov paib tseem ceeb.
• Koj yuav tau txais tshuaj los tiv thaiv GVHD thiab tiv thaiv los yog kho kab mob, nrog rau tshuaj tua kab mob, tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob.
• Tej zaum koj yuav xav tau cov ntshav ntxiv rau ntau lub.
• Koj yuav raug pub noj ntawm txoj leeg (IV) kom txog thaum koj tuaj yeem noj ntawm qhov ncauj, thiab lub plab phiv thiab qhov ncauj tawm mus.

Tom qab koj tawm hauv lub tsev kho mob, nco ntsoov ua raws cov lus qhia yuav ua li cas saib xyuas koj tus kheej hauv tsev.

Koj ua tau zoo npaum li cas tom qab hloov ntshav yog nyob ntawm:

• Txoj kev hloov hlwb pob txha
• Ntev npaum li cas tus pub lub hlwb piv koj li
• Koj muaj hom mob cancer lossis mob dab tsi
• Koj lub hnub nyoog thiab kev noj qab haus huv tag nrho
• Hom thiab ntau npaum li cas ntawm kev kho mob lossis tshuaj tua hluav taws xob uas koj tau muaj ua ntej koj hloov ntshav
• Lwm yam teeb meem koj tuaj yeem muaj

Kev hloov hlwb pob txha tuaj yeem kho lossis kho qee yam kho koj tus mob. Yog tias qhov hloov ntshav tau ua tiav, koj tuaj yeem rov qab mus rau feem ntau ntawm koj cov kev ua ub no ib txwm sai li sai tau yog koj qhov koj noj qab nyob zoo. Feem ntau nws yuav siv sij hawm txog 1 xyoos kom rov zoo siab, nyob ntawm seb muaj teeb meem dab tsi tshwm sim.

Kev mob lwm yam los yog tsis tiav ntawm cov qog pob txha tuaj yeem ua rau tuag taus.

Kev Hloov Pauv - hlwb pob txha; Qia cell hloov; Hematopoietic qia cell hloov; Txo cov kev siv dag zog tsis siv neeg qhov kev hloov pauv tsis raug; Mini hloov pauv; Allogenic pob txha hloov; Autologous hlwb pob txha hloov pauv; Umbilical qaum ntshav hloov ntshav; Aplastic anemia - hloov hlwb pob txha; Kab mob hlwb - hloov hlwb pob txha; Lymphoma - hloov hlwb pob txha; Ntau lub myeloma - hloov hlwb pob txha

• Los ntshav thaum kho mob cancer
• Hloov cev pob txha - hloov ntshav tawm
• Central venous catheter - hloov pauv khaub ncaws
• Central venous catheter - yaug
• Dej haus kom nyab xeeb thaum kho cancer
• Lub qhov ncauj qhuav thaum kho mob cancer
• Noj zaub mov kom tshaj thaum mob - cov neeg laus
• Noj ntau calories thaum koj muaj mob - menyuam yaus
• Qhov ncauj mucositis - kev saib xyuas tus kheej
• Peripherally tso central catheter - yaug
• Muaj kev nyab xeeb noj thaum kho mob cancer

• Mob hlwb pob txha tsis muaj kev cia siab
• Tsim cov ntsiab ntawm cov ntshav
• Mob pob txha los ntawm ntsag
• Hloov pob txha-txha caj qaum - series

American Society of Clinical Oncology lub vev xaib. Hloov hlwb pob txha yog dab tsi (qia hloov ntshav ntawm tes)? www.cancer.net/navigating-cancer-care/how-cancer-treated/bone-marrowstem-cell-transplantation/what-bone-marrow-transplant-stem-cell-transplant. Hloov tshiab Lub Yim Hli 2018. Mus saib Lub Ob Hlis 13, 2020.

Heslop HE. Txheej txheem cej luam thiab xaiv cov neeg pub nyiaj ntawm hematopoietic qia cell hloov chaw. Hauv: Hoffman R, Benz EJ, Silberstein LE, li al, eds. Hematology: Qhov Ntsiab Cai thiab Kev Coj UaCov. 7 tus ed. Philadelphia, PA: Elsevier; 2018: chap 103.

Im A, Pavletic SZ. Hematopoietic qia cell hloov pauv. Hauv: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical OncologyCov. 6 tus ed. Philadelphia, PA: Elsevier; 2020: chap 28.