Progeria
Progeria yog ib yam muaj tshwm sim tsawg tsawg uas ua rau muaj hnub nyoog loj hauv cov menyuam yaus.
Progeria yog tus mob uas tsis tshua muaj heev. Nws yog qhov zoo tshaj plaws vim tias nws cov tsos mob zoo ib yam li tib neeg kev laus, tab sis nws tshwm sim hauv cov menyuam yaus. Feem ntau, nws tsis dhau los ntawm cov tsev neeg. Nws tsis tshua pom muaj ntau dua ib tus menyuam hauv tsev neeg.
Cov tsos mob muaj xws li:
- Kev loj hlob tsis ua haujlwm nyob rau thawj xyoo ntawm lub neej
- Nqaim, ntsej muag lossis ntsej muag ntsej muag
- Tshuav
- Poob lub pob muag thiab plaub muag
- Luv luv
- Lub taub hau loj rau qhov loj ntawm lub ntsej muag (macrocephaly)
- Qhib cov nqaij mos muag (fontanelle)
- Cov puab tsaig me me (micrognathia)
- Qhuav, nplai, daim tawv nyias
- Cov khoom lag luam tsawg tsawg
- Cov hniav - ncua lossis tsis tuaj
Tus kws kho mob yuav kuaj xyuas lub cev thiab kuaj lub tsev ntsuas. Qhov no yuav qhia:
- Insulin kuj
- Daim tawv hloov pauv zoo ib yam li pom nyob rau hauv scleroderma (cov nqaij sib txuas los ua tawv thiab tawv)
- Feem ntau cov roj (cholesterol) thiab triglyceride ntau ntau
Kev ntsuam xyuas mob plawv tuaj yeem qhia pom cov tsos mob thaum ntxov ntawm cov hlab ntshav txhaws.
Kev tshuaj ntsuam caj ces tuaj yeem tshawb pom cov kev hloov hauv noob (LMNA) uas ua rau muaj progeria.
Tsis muaj kev kho tshwj xeeb rau tus mob progeria. Cov tshuaj aspirin thiab statin tuaj yeem siv los tiv thaiv lub plawv lossis mob stroke.
Progeria Tshawb Fawb Foundation, Inc. - www.progeriaresearch.org
Progeria ua rau muaj kev tuag ntxov. Cov neeg muaj tus mob feem ntau tsuas yog ua neej nyob nrog lawv cov hluas (lub neej nruab nrab ntawm 14 xyoo). Txawm li cas los xij, qee qhov tuaj yeem nyob rau lawv lub 20s thaum ntxov. Cov ua rau ploj tuag feem ntau cuam tshuam rau lub plawv lossis cov hlab ntsha tawg.
Teeb meem yuav suav nrog:
- Plawv nres (myocardial infarction)
- Mob stroke
Hu rau koj tus kws kho mob yog koj tus menyuam tsis zoo li loj hlob lossis loj hlob tsis tu ncua.
Hutchinson-Gilford cov leeg mob siab ntsws; HGPS
- Cov hlab ntshav txhaws
Gordon LB. Hutchinson-Gilford cov leeg mob siab ntsws (progeria). Hauv: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Phau Ntawv ntawm PediatricsCov. 21st ed. Philadelphia, PA: Elsevier; 2020: cha 109.
Gordon LB, Brown WT, Collins FS. Hutchinson-Gilford kev mob tshwm sim. GeneReviewsCov. Xyoo 2015: 1. PMID: 20301300 www.ncbi.nlm.nih.gov/pubmed/20301300. Hloov kho Lub Ib Hlis 17, 2019. Nkag mus Lub Xya Hli 31, 2019.