Tus Sau: Gregory Harris
Hnub Kev Tsim: 8 Lub Plaub Hlis Ntuj 2021
Hloov Hnub: 4 Lub Kaum Ib Hli Ntuj 2024
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Ntau qhov system atrophy - hom parkinsonian - Tshuaj Kho Mob
Ntau qhov system atrophy - hom parkinsonian - Tshuaj Kho Mob

Ntau hom kab mob atrophy-parkinsonian hom (MSA-P) yog ib yam mob uas tsis tshua pom muaj tshwm sim zoo li tus kab mob Parkinson. Txawm li cas los xij, cov neeg uas muaj MSA-P muaj kev puas tsuaj ntau dua rau cov ntu ntawm cov leeg hlwb uas tswj cov haujlwm tseem ceeb xws li lub plawv dhia, ntshav siab, thiab tawm hws.

Lwm qhov ploj ntawm MSA yog MSA-cerebellar. Nws feem ntau cuam tshuam rau thaj chaw sib sib zog nqus ntawm lub hlwb, tsuas yog siab dua tus txha nqaj qaum.

Qhov ua rau MSA-P tsis tau paub meej. Cov cheeb tsam uas cuam tshuam ntawm lub hlwb tau sib tshooj nrog thaj chaw cuam tshuam los ntawm tus kab mob Parkinson, nrog cov tsos mob zoo sib xws. Vim li no, subtype ntawm MSA no yog hu ua parkinsonian.

MSA-P feem ntau raug tshuaj rau cov txiv neej laus dua 60 xyoo.

MSA ua rau cov leeg hlwb puas tsuaj. Tus kab mob nyhav nyhav zuj zus. Li ntawm ib nrab ntawm cov neeg uas muaj MSA-P tau xiam feem ntau ntawm lawv cov kev siv lub cev muaj zog hauv thaj tsam 5 xyoos ntawm qhov pib ntawm tus kab mob.

Cov tsos mob tuaj yeem suav nrog:

  • Tus tsim hluav taws xob
  • Kev txav nyuaj, xws li qeeb qeeb, poob ntawm kev tshuav, tshee thaum taug kev
  • Nquag poob
  • Mob leeg thiab mob (myalgia), thiab txhav
  • Cov ntsej muag pauv hloov, xws li kev tiv thaiv zoo li lub ntsej muag thiab lub ntsej muag
  • Nyuaj dhau los zom lossis nqos (qee zaus), tsis tuaj yeem kaw lub qhov ncauj
  • Kev cuam tshuam cov qauv pw tsaug zog (feem ntau thaum lub qhov muag ceev nrawm [REM] pw lig thaum hmo ntuj)
  • Kiv taub hau lossis tsaus muag thaum sawv ntsug lossis tom qab sawv ntsug
  • Teeb meem Erection
  • Plam ntawm kev tswj kom tso quav lossis tso zis
  • Cov teeb meem ntawm kev ua si uas yuav tsum tau txav me me (poob zoo ntawm lub cev muaj zog zoo), xws li sau ntawv uas yog qhov me me thiab nyeem nyuaj
  • Poob tawm hws nyob rau txhua qhov ntawm lub cev
  • Txiav hauv lub siab
  • Xeev siab thiab teeb meem nrog kev zom zaub mov
  • Cov teeb meem hwj tau lub cev, xws li tsis khov kho, dawm taw, los yog dhau mus
  • Lub zeem muag hloov, txo qis lossis qhov muag plooj
  • Lub suab thiab hais lus hloov

Lwm tus tsos mob uas yuav tshwm sim nrog tus kab mob no:


  • Tsis meej pem
  • Kev nyuaj siab
  • Kev Nyuaj Siab
  • Kev pw tsaug zog uas cuam tshuam txog kev ua pa, nrog rau kev pw tsaug zog apnea lossis thaiv ntawm cov pa cua uas ua rau lub suab nrov hnyav tshee

Koj tus kws kho mob yuav tshuaj xyuas koj, thiab kuaj koj ob lub qhov muag, leeg ntshav, thiab leeg.

Koj cov ntshav siab yuav noj thaum koj pw thiab sawv ntsug.

Kuj tsis muaj ib qho kev kuaj mob twg kom pom tseeb tus mob no. Tus kws kho mob uas paub tshwj xeeb hauv cov hlab hlwb (tus neurologist) tuaj yeem ua tus mob raws li:

  • Keeb kwm ntawm cov tsos mob
  • Cov mus kuaj lub cev
  • Kev txiav tawm lwm yam ua rau cov tsos mob tshwm sim

Kev sim tshuaj kom pab tshawb nrhiav qhov tseeb tuaj yeem suav nrog:

  • MRI ntawm lub taub hau
  • Plasma norepinephrine ntau ntau
  • Kuaj tshuaj rau cov khoom noj tsis zoo norepinephrine (tso zis tso kua txiv)

Tsis muaj ib txoj kev kho tau tus mob MSA-P. Tsis muaj ib txoj kev paub tiv thaiv tus kab mob kom txhob mob ntau ntxiv. Lub hom phiaj ntawm kev kho mob yog tswj hwm tus mob.


Dopaminergic cov tshuaj, xws li levodopa thiab carbidopa, tuaj yeem siv txo qis tshee thaum ntxov lossis tshee.

Tab sis, rau ntau tus neeg uas muaj MSA-P, cov tshuaj no tsis ua haujlwm zoo.

Cov tshuaj kho mob yuav raug siv los kho ntshav siab.

Qhov ntsuas ntshav dhia uas yog tsim los txhawb lub plawv dhia ceev ceev (nrawm dua 100 rab koob ib feeb) yuav nce ntshav siab rau qee cov neeg.

Cem quav yuav kho tau nrog kev noj haus muaj txiaj ntsig zoo thiab kev noj kom tsaug zog. Muaj tshuaj kho tau teeb meem erection.

Xav paub cov ntaub ntawv ntau ntxiv thiab txhawb nqa rau cov neeg uas muaj MSA-P thiab lawv tsev neeg tuaj yeem nrhiav tau ntawm:

  • Koom Haum Koom Tes rau Cov Kab Mob Tsis Txaus - rarediseases.org/rare-diseases/multiple-system-atrophy
  • MSA Pab Koom Tes - www.multiplesystematrophy.org/msa-resources/

Qhov tshwm sim rau MSA yog pluag. Plam ntawm lub hlwb thiab lub cev kom qeeb zuj zus. Ntxov kev tuag ntxov yuav muaj feem ntau. Cov neeg feem ntau nyob 7 rau 9 xyoo tom qab kuaj pom.

Hu rau koj tus kws kho mob yog tias koj muaj cov tsos mob ntawm qhov kev tsis zoo no.


Hu rau koj tus kws kho mob yog tias koj tau pom tias muaj mob MSA thiab koj cov kev mob tshwm sim rov qab los lossis hnyav dua. Hu rau yog tias muaj cov tsos mob tshiab tshwm sim, suav nrog kev siv tshuaj tsis haum, xws li:

  • Hloov pauv ntawm kev ras txog / tus cwj pwm / kev xav
  • Tus cwj pwm tsis zoo
  • Kiv taub hau
  • Kev Ua Si
  • Kev txav tsis ua haujlwm
  • Poob ntawm lub hlwb kev ua haujlwm
  • Xeev siab los ntuav
  • Kev kub ntxhov loj lossis tsis meej pem

Yog tias koj muaj ib tus neeg hauv koj tsev neeg nrog MSA thiab lawv tus mob poob qis txog qhov uas koj tsis tuaj yeem saib xyuas tus neeg nyob hauv tsev, nrhiav tswv yim los ntawm koj tsev neeg cov kws khomob.

Cov tsos mob txaj muag; Neurologic orthostatic hypotension; Cov tsos mob txaj muag-McGee-Drager; Parkinson plus syndrome; MSA-P; MSA-C

  • Nruab nrab hauv lub paj hlwb thiab lub paj hlwb peripheral

Fanciulli A, Wenning GK. Ntau-system atrophy. N Engl J MedCov. Xyoo 2015; 372 (3): 249-263. PMID: 25587949 pubmed.ncbi.nlm.nih.gov/25587949/.

Jankovic J. Kab Mob Parkinson thiab lwm yam kev txawv txav. Hauv: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology nyob rau hauv Kev Soj NtsuamCov. 7 tus ed. Philadelphia, PA: Elsevier; 2016: tshooj 96.

Romero-Ortuno R, Wilson KJ, Hampton JL. Kev ua tsis taus ntawm autonomic lub paj hlwb. Hauv: Sau HM, Rockwood K, Young J, eds. Brocklehurst's Cov Ntawv Phau Ntawv Txog Tshuaj Geriatric thiab GerontologyCov. 8 tus ed. Philadelphia, PA: Elsevier; 2017: cha 63.

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